• 제목/요약/키워드: threshold discharge

검색결과 69건 처리시간 0.027초

Comparative Study on the Nociceptive Responses Induced by Whole Bee Venom and Melittin

  • Shin, Hong-Kee;Lee, Kyung-Hee;Lee, Seo-Eun
    • The Korean Journal of Physiology and Pharmacology
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    • 제8권5호
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    • pp.281-288
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    • 2004
  • The present study was undertaken to confirm whether melittin, a major constituent of whole bee venom (WBV), had the ability to produce the same nociceptive responses as those induced by WBV. In the behavioral experiment, changes in mechanical threshold, flinching behaviors and paw thickness (edema) were measured after intraplantar (i.pl.) injection of WBV (0.1 mg & 0.3 mg/paw) and melittin (0.05 mg & 0.15 mg/paw), and intrathecal (i.t.) injection of melittin $(6{\mu}g)$. Also studied were the effects of i.p. (2 mg & 4 mg/kg), i.t. $(0.2{\mu}g\;&\;0.4{\mu}g)$ or i.pl. (0.3 mg) administration of morphine on melittin-induced pain responses. I.pl. injection of melittin at half the dosage of WBV strongly reduced mechanical threshold, and increased flinchings and paw thickness to a similar extent as those induced by WBV. Melittin- and WBV-induced flinchings and changes in mechanical threshold were dose- dependent and had a rapid onset. Paw thickness increased maximally about 1 hr after melittin and WBV treatment. Time-courses of nociceptive responses induced by melittin and WBV were very similar. Melittin-induced decreases in mechanical threshold and flinchings were suppressed by i.p., i.t. or i.pl. injection of morphine. I.t. administration of melittin $(6{\mu}g)$ reduced mechanical threshold of peripheral receptive field and induced flinching behaviors, but did not cause any increase in paw thickness. In the electrophysiological study, i.pl. injection of melittin increased discharge rates of dorsal horn neurons only with C fiber inputs from the peripheral receptive field, which were almost completely blocked by topical application of lidocaine to the sciatic nerve. These findings suggest that pain behaviors induced by WBV are mediated by melittin-induced activation of C afferent fiber, that the melittin-induced pain model is a very useful model for the study of pain, and that melittin-induced nociceptive responses are sensitive to the widely used analgesics, morphine.

국지홍수 심도예측을 위한 새로운 홍수지수의 개발 (Development of a New Flood Index for Local Flood Severity Predictions)

  • 조덕준;손인욱;최현일
    • 한국수자원학회논문집
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    • 제46권1호
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    • pp.47-58
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    • 2013
  • 최근 들어 전 세계적인 기후변화 양상에 따라 짧은 시간에 큰 유출양상을 보이는 국지적 돌발성 홍수의 발생이 증가하는 추세이며 이로 인한 인명 및 재산의 피해가 국내뿐만 아니라 전 세계적으로 발생하고 있다. 이와 같이 소규모 지역의 집중된 강우로 발생하는 국지적 돌발성 홍수는 빠른 수문반응으로 인하여 홍수피해를 예방하기 위한 예 경보 시간이 부족한 것이 특징이다. 국지 홍수로 인한 피해를 막기 위해서는 한계유량을 초과하여 제내지의 피해발생 가능성이 있는 홍수사상에 대한 심도예측이 중요하다. 본 논문의 목적은 소규모 유역에서 발생하는 홍수사상의 심각성 정도를 정량화할 수 있는 새로운 홍수지수(New Flood Index)를 개발하고 새로운 홍수지수와 강우특성과의 회귀분석을 통하여 국지 돌발홍수예측에 적용하고자 하였다. 2개의 시범유역들에 대한 홍수유출수문곡선은 장기간 관측된 연최대치계열 실측 강우자료를 이용하여 강우-유출 모형을 통하여 산정하였다. 새로운 홍수지수 NFI는 2년 빈도 홍수량으로 가정된 한계유량을 초과하는 홍수사상에 대하여, 첨두홍수량비, 상승부경사, 초과홍수지속시간 등 홍수 유출수문곡선의 특성을 이용한 3가지 상대심도계수의 기하학적 평균값으로산정하였다. 분석결과 3시간최대강우가 새로운 홍수지수NFI와 가장높은 상관관계가 있음을 확인하였다. 새로운 홍수지수와 강우특성과의 회귀분석을 통해 얻어진 최적 관계식은 소규모 미계측 유역에서의 국지적 홍수 심도예측을 위한 예비정보의 기초자료로 활용될 수 있을 것으로 기대된다.

음향기술을 이용한 전력용 변압기 예방진단 (Diagonoses of Power Transformer Using Acoustic Emission Techniques)

  • 황선주;곽희로;전희종;김재철;박재완;최수안
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1992년도 하계학술대회 논문집 B
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    • pp.938-941
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    • 1992
  • This paper presents an acoustic emission(AE) technique using ultrasonic sensors to diagonize power transformers. Conventional methods detect and measure the electrical signal of the partial discharge(PD) of transformers in operation. The proposed techniques measures the acoustic signal generated by the partial discharge, and counts the number of the waveforms above a threshold to diagonize transformers. Experiments showed that the proposed method improved diagonosis capability over the conventional PD method.

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Uncertainty Analysis of Flash-flood Prediction using Remote Sensing and a Geographic Information System based on GcIUH in the Yeongdeok Basin, Korea

  • Choi, Hyun;Chung, Yong-Hyun;Yoon, Hong-Joo
    • 대한원격탐사학회:학술대회논문집
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    • 대한원격탐사학회 2006년도 Proceedings of ISRS 2006 PORSEC Volume II
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    • pp.884-887
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    • 2006
  • This paper focuses on minimizing flood damage in the Yeongdeok basin of South Korea by establishing a flood prediction model based on a geographic information system (GIS), remote sensing, and geomorphoclimatic instantaneous unit hydrograph (GcIUH) techniques. The GIS database for flash flood prediction was created using data from digital elevation models (DEMs), soil maps, and Landsat satellite imagery. Flood prediction was based on the peak discharge calculated at the sub-basin scale using hydrogeomorphologic techniques and the threshold runoff value. Using the developed flash flood prediction model, rainfall conditions with the potential to cause flooding were determined based on the cumulative rainfall for 20 minutes, considering rainfall duration, peak discharge, and flooding in the Yeongdeok basin.

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운전중 부분방전 진단시스템을 위한 복합 잡음제거 기법 (A Complex Noise Suppression Algorithm for On-line Partial Discharge Diagnosis Systems)

  • 이상화;윤영우;추영배;강동식
    • 전기학회논문지
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    • 제58권2호
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    • pp.342-348
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    • 2009
  • This paper introduces a novel denoising algorithm for the partial-discharge(PD) signals from power apparatuses. The developed algorithm includes three kinds of specific denoising sub-algorithms. The first sub-algorithm uses the fuzzy logic which classifies the noise types in the magnitude versus phase PD pattern. This sub-algorithm is especially effective in the rejection of the noise with high and constant magnitude. The second one is the method simply removing the pulses in the phase sections below the threshold count in the count versus phase pattern. This method is effective in removing the occasional high level noise pulses. The last denoising sub-algorithm uses the grouping characteristics of PD pulses in the 3D plot of the magnitude versus phase versus cycle. This special technique can remove the periodical noise pulses with varying magnitudes, which are very difficult to be removed by other denoising methods. Each of the sub-algorithm has different characteristic and shows different quality of the noise rejection. On that account, a parameter which numerically expresses the noise possessing degree of signal, is defined and evaluated. Using the parameter and above three sub-algorithms, an adaptive complex noise rejection algorithm for the on-line PD diagnosis system is developed. Proposed algorithm shows good performances in the various real PD signals measured from the power apparatuses in the Korean plants.

Stream flow estimation in small to large size streams using Sentinel-1 Synthetic Aperture Radar (SAR) data in Han River Basin, Korea

  • Ahmad, Waqas;Kim, Dongkyun
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2019년도 학술발표회
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    • pp.152-152
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    • 2019
  • This study demonstrates a novel approach of remotely sensed estimates of stream flow at fifteen hydrological station in the Han River Basin, Korea. Multi-temporal data of the European Space Agency's Sentinel-1 SAR satellite from 19 January, 2015 to 25 August, 2018 is used to develop and validate the flow estimation model for each station. The flow estimation model is based on a power law relationship established between the remotely sensed surface area of water at a selected reach of the stream and the observed discharge. The satellite images were pre-processed for thermal noise, radiometric, speckle and terrain correction. The difference in SAR image brightness caused by the differences in SAR satellite look angle and atmospheric condition are corrected using the histogram matching technique. Selective area filtering is applied to identify the extent of the selected stream reach where the change in water surface area is highly sensitive to the change in stream discharge. Following this, an iterative procedure called the Optimum Threshold Classification Algorithm (OTC) is applied to the multi-temporal selective areas to extract a series of water surface areas. It is observed that the extracted water surface area and the stream discharge are related by the power law equation. A strong correlation coefficient ranging from 0.68 to 0.98 (mean=0.89) was observed for thirteen hydrological stations, while at two stations the relationship was highly affected by the hydraulic structures such as dam. It is further identified that the availability of remotely sensed data for a range of discharge conditions and the geometric properties of the selected stream reach such as the stream width and side slope influence the accuracy of the flow estimation model.

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Functional Characteristics of Lumbar Spinal Neurons Projecting to Midbrain Area in Rats

  • Park, Sah-Hoon;Kim, Geon
    • The Korean Journal of Physiology
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    • 제28권2호
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    • pp.113-122
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    • 1994
  • The present study was carried out to characterize the functional properties of spinomesencephalic tract (SMT) neurons in the lumbar spinal cord of urethane anesthetized rats. Extracellular single unit recordings were made from neurons antidromically activated by stimulation of the midbrain area, including the deep layers of superior colliculus, periaqueductal gray and midbrain reticular formation. Recording sites were located in laminae I-VII of spinal cord segments of L2-L5. Receptive field properties and responses to calibrated mechanical stimulation were studied in 78 SMT cells. Mean conduction velocity of SMT neurons was $19.1{\pm}1.04\;m/sec$. SMT units were classified according to their response profiles into four groups: wide dynamic range (58%), deep/tap (23%), high threshold (9%) and low threshold (3%). A simple excitatory receptive field was found for most SMT neurons recorded in superficial dorsal horn (SDH). Large complex inhibitory and/or excitatory receptive fields were found for cells in lateral reticulated area which usually showed long after-discharge. Most of SMT cells received inputs from $A{\delta}$ and C afferent fiber types. These results suggest that sensory neurons in the rat SMT may have different functional roles according to their location in the spinal cord in integrating and processing sensory inputs including noxious mechanical stimuli.

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Flyback 방식을 이용한 on-wafer용 HBM ESD 테스터 구현 (HBM ESD Tester for On-wafer Test using Flyback Method)

  • 박창근;염기수
    • 한국정보통신학회논문지
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    • 제6권7호
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    • pp.1079-1083
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    • 2002
  • 반도체 소자의 정전기 내성을 알아보기 위해 필요한 HBM ESD 테스터를 작자하였다 .HBM ESD 테스트는 MMIC의 정전기 내성을 측정하는 데 가장 많이 사용하는 방식이다. 고전압의 ESD 신호론 얻기 위하여 DC-DC converter의 일종인 flyback 방식온 도입하였다. Flyback 방식으로 제자된 HBM ESD 테스터는 고전압 부분과 저전압 부분을 서로 격리시킬 수 있는 장점이 있다 스위치로 사용된 relay의 air gap을 이용하여 정전기의 rise time이 국제 규격에 맡도록 설계하였다. 결과적으로, flyback 방식과 relay의 air gap을 이용하여 기생 성분이 최소화된 ESD 테스터를 제작하였다.

Flyback방식을 이용한 on-wafer용 HBM ESD 테스터 구현 (HBM ESD Tester for On-wafer Test using Flyback Method)

  • 박창근;염기수
    • 한국정보통신학회:학술대회논문집
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    • 한국해양정보통신학회 2002년도 추계종합학술대회
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    • pp.469-472
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    • 2002
  • 반도체 소자의 정전기 내성을 알아보기 위해 필요한 HBM ESD 테스터를 제작하였다. HBM ESD 테스트는 MMIC의 정전기 내성을 측정하는데 가장 많이 사용하는 방식이다. 고전압의 ESD 신호를 얻기 위하여 DC-DC converter의 일종인 flyback 방식을 도입하였다. Flyback 방식으로 제작된 HBM ESD 테스터는 고전압 부분과 저전압 부분을 서로 격리시킬 수 있는 장점이 있다. 스위치로 사용된 relay의 air gap을 이용하여 정전기의 rise time이 국제 규격에 맞도록 설계하였다. 결과적으로, flyback 방식과 relay의 air gap을 이용하여 기생 성분이 최소화된 ESD 테스터를 제작하였다.

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Anneal Temperature Effects on Hydrogenated Thin Film Silicon for TFT Applications

  • Ahn, Byeong-Jae;Kim, Do-Young;Yoo, Jin-Su;Junsin Yi
    • Transactions on Electrical and Electronic Materials
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    • 제1권2호
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    • pp.7-11
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    • 2000
  • a-Si:H and poly-Si TFT(thin film transistor) characteristics were investigated using an inverted staggered type TFT. The TFT an as-grown a-Si:H exhibited a low field effect mobility, transconductance, and high gate threshold voltage. The poly-Si films were achieved by using an isothermal and RTA treatment for glow discharge deposited a-Si:H films. The a-Si:H films were cystallized at the various temperature from 600$^{\circ}C$ to 1000$^{\circ}C$. As anneal temperature was elevated, the TFT exhibited increased g$\sub$m/ and reduced V$\sub$ds/. V$\sub$T/. The poly-Si grain boundary passivation with grain boundary trap types and activation energies as a function of anneal temperature. The poly-si TFT showed an improved I$\sub$nm//I$\sub$off/ ratio of 10$\^$6/, reduced gate threshold voltage, and increased field effect mobility by three orders.

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