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Torsade de Pointes Associated with Hypomagnesemia after Open Heart Surgery - A Report of 2 Cases - (개심술후 저마그네슘증에 동반된 Torsade de Pointes;치험 2례 보고)

  • 노환규
    • Journal of Chest Surgery
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    • v.25 no.2
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    • pp.188-193
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    • 1992
  • Life-threatening cardiac arrhythmia is a frequent complication of open heart surgery. There are many causes of postoperative cardiac arrhythmias. Electrolyte imbalance such as hypokalemia and acidemia are major causes of ventricular arrhythmias. Infrequently, however, antiarrhythmic agents and /or hypomagnesemia induce[s] a ventricular arrhythmia such as "torsade de pointes" by increasing the repolarization time of myocardium, Recently, we have experienced two cases of "Torsade de pointes" associated with hyp-omagnesemia after replacement of mitral valve and one of whom after use of procainamide. Intravenous infusion of magnesium immediately and successfully abolished the torsade de pointes in both cases.intes in both cases.

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Re-expansion Pulmonary Edema -2 Cases Report- (재팽창 폐부종 치험 2례 보고)

  • 강경민
    • Journal of Chest Surgery
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    • v.28 no.1
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    • pp.81-84
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    • 1995
  • Re-expansion pulmonary edema following pneumothorax or hemothorax is clinically uncommon but occasionally life threatening. Clinical details are given of two patients.Ipsilateral pulmonary edema were developed after chest tube insertion due to spontaneous pneumothorax in case I and after evacuation of postoperative hemothorax in case II. The patients were treated with frequent bronchial toilet.The administration of colloid solution and diuretics was effective. The possible mechanisms underlying the edema are discussed.Both increased time of collapse and suction tended to correlate with reexpansion edema.The present two cases provided evidence for longstanding lung collapse and immediate application of suction.

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Acute Postpneumonectomy Empyema with Bronchopleural Fistula Treated with Vacuum-assisted Closure Device

  • Han, Woo-Sik;Kim, Kwhan-Mien
    • Journal of Chest Surgery
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    • v.45 no.4
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    • pp.260-262
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    • 2012
  • Postpneumonectomy empyema is a life-threatening complication, which is often related with a bronchopleural fistula. After surgical repair of fistula, sterilization of infected pleural cavity is important and usually carried out by long-term cyclic irrigation. We report a case in which vacuum-assisted closure device was successfully applied to sterilize the pleural cavity and obliterate bronchopleural fistula.

An infant with a palatal fistula secondary to Candida infection

  • Sharma, Sarwpriya;Chauhan, Jaideep Singh
    • Archives of Craniofacial Surgery
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    • v.21 no.3
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    • pp.206-209
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    • 2020
  • Candida osteomyelitis affecting maxillofacial bones has been scantly documented in the literature. Infantile osteomyelitis is an uncommon and life-threatening disease. Candida osteomyelitis causes significant morbidity. The present report describes a case of a 9-month-old infant with infantile osteomyelitis secondary to candida infection. This report describes its presentation and the management of palatal fistula in an infant.

Management of Otogenic Brain Abscess Using the Transmastoid Approach

  • Choi, June;Choi, Jong Il;Kim, Sang-Dae
    • Journal of Korean Neurosurgical Society
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    • v.55 no.3
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    • pp.178-180
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    • 2014
  • Despite significant advances in the treatment of all forms of chronic otitis media (COM), complications still can and do occur, with intracranial complications representing the most life-threatening cases, often requiring immediate therapeutic intervention. Herein, we present a rare case of rapidly progressing facial paralysis with concomitant severe headache and ipsilateral hearing loss secondary to an otogenic brain abscess, treated with the transmastoid approach, drainage, and facial nerve decompression.

Macrophage Activation Syndrome Presented in a Case of Neonatal Lupus

  • Kang, Chang Min;Choi, Jinwha;Lee, JungHwa
    • Neonatal Medicine
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    • v.28 no.3
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    • pp.139-142
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    • 2021
  • Macrophage activation syndrome (MAS) is a potentially life-threatening complication in many autoimmune diseases. Early recognition and intervention are essential for a favorable outcome. Neonatal lupus, an acquired autoimmune disease in neonates caused by the transplacental passage of maternal autoantibodies, is rare and usually self-limited. Herein, we report a case of MAS in a patient with neonatal lupus, which improved with intravenous immunoglobulin.

Two Cases of Gastric Volvulus in Neonates

  • Kim, Min Yeong;Park, Moon Sung;Lee, Jang Hoon
    • Neonatal Medicine
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    • v.28 no.1
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    • pp.36-40
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    • 2021
  • Gastric volvulus in neonates is an extremely uncommon disorder, which is challenging to diagnose because of its non-specific clinical manifestations. Early diagnosis of gastric volvulus is important to avoid life-threatening complications, such as gastric ischemia, necrosis, and perforation. A definitive diagnosis could be made with radiological upper gastrointestinal series. In this report, we present two cases of neonate gastric volvulus, which were confirmed by radiological upper gastrointestinal series, and the patients underwent surgical treatment.

A Review of HLA Genes in Pharmacogenetics: Risk Assessment of Adverse Drug Reactions

  • Yu, Shinae
    • Journal of Interdisciplinary Genomics
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    • v.3 no.1
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    • pp.7-12
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    • 2021
  • Adverse drug reactions (ADRs) is a hypersensitivity reactions to specific medications, and remain a common and major problem in healthcare. ADRs suchc as drug-induced liver injury and life-threatening severe cutaneous adverse drug reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug rash with eosinophilia and systemic symptoms can be occurred by uncontrolled expansion of oligoclonal T cells according to genetically predisposing HLA. In this review, I summarized the alleles of HLA genes which have been proposed to have association with ADRs caused by different drugs.

Inductive Effects of Vibrio vulnificus Infections on Cytotoxic Activity and Expression of Inflammatory Cytokine Genes in Human Intestinal Epithelial Cells

  • Lee, Byung-Cheol;Kim, Tae-Sung
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.132.2-132.2
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    • 2003
  • Vibrio vulnificus, a Gram-negative estuarine bacterium, is the causative agent of food-borne diseases, such as life-threatening septicemia. V. vulnificus penetrating into the intestinal epithelial barrier stimulates an inflammatory response in the adjacent intestinal mucosa. Therefore, interaction between V. vulnificus and intestinal cells is important for understanding of both the immunology of mucosal surfaces and V. vulnificus. In this study we investigated the effects of V. vulnificus infection on cytokine gene expression of human intestinal epithelial cells, Caco-2 and INT-407 cells. (omitted)

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