Neonatal Medicine

The Korean Society of Neonatology (대한신생아학회)
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Macrophage Activation Syndrome Presented in a Case of Neonatal Lupus

  • Kang, Chang Min (Department of Pediatrics, Korea University Guro Hospital, Korea University College of Medicine) ;
  • Choi, Jinwha (Department of Pediatrics, Korea University Guro Hospital, Korea University College of Medicine) ;
  • Lee, JungHwa (Department of Pediatrics, Korea University Guro Hospital, Korea University College of Medicine)
  • Received : 2021.06.28
  • Accepted : 2021.08.10
  • Published : 2021.08.31
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Abstract

Macrophage activation syndrome (MAS) is a potentially life-threatening complication in many autoimmune diseases. Early recognition and intervention are essential for a favorable outcome. Neonatal lupus, an acquired autoimmune disease in neonates caused by the transplacental passage of maternal autoantibodies, is rare and usually self-limited. Herein, we report a case of MAS in a patient with neonatal lupus, which improved with intravenous immunoglobulin.

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References

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