• Title/Summary/Keyword: threatening

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Comparison of Moxifloxacin Monotherapy versus Cephalosporin-Azithromycin Combination Therapies for the Treatment of Community Acquired Pneumonia (원외획득폐렴 환자 치료에서 Moxifloxacin 단독요법과 Cephalosporin-Azithromycin 병용요법의 비교)

  • Cheong, Eun-Jin;Lee, Suk-Hyang
    • Korean Journal of Clinical Pharmacy
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    • v.15 no.2
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    • pp.75-81
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    • 2005
  • Community acquired pneumonia (CAP) remains a prevalent and potentially life threatening illness. American Thoracic Society and Infectious Disease Society America recommend combination therapies with ${\beta}-lactam$ plus a macrolide or a fluoroquinolone monotherapy for the empirical treatment of CAP. The aim of this study was to compare moxifloxacin monotherapy with cephalosporin plus azithromycin combination therapies. From January 2004 to March 2005, 18 patients in the moxifloxacin group(MG) and 21 patients in the cefuroxime or ceftriaxone plus azithromycin group(CAG) with CAP were retrospectively reviewed with regard to clinical, laboratory and microbiological data. Each patient was stratified into mild (risk class I-II), moderate (risk class III) and severe (risk class VI, V) group according to and PSI (Pneumonia Severity Index) score. Each group was compared for microbiological eradication, clinical assessment, the length of hospital stay. As results, Total 39 patients with CAP were reviewed. The appropriateness of admission was 83.3% in MC vs. 76.2% in CAC. The mean length of the hospital day was for 8.31 days vs. 7.39 days, days switching parenteral to oral antibiotics in 5.19 days vs. 5.28 days, clinical improvement in 2.43 days vs. 2.61 days in MG vs. CAC. Radiological improvement required 3.75 days vs 3.63 days in MG vs. CAG and bacteriological eradication rate at discharge was the same in the both groups. Mortality rate was 11.1% (2 of 18) vs 14.3% (3 of 21) in MG vs. CAG (p=0.77). Drug cost of the mean 5 hospital days requiring parenteral antibiotics was the most inexpensive in moxifloxacin group for the 147,045 won, and ceftriaxone 1g-azithromycin group for the 170,285 won, cefuroxime bid-azithromycin group for the 207,800 won, ceftriaxone 2g-azithromycin group far the 220,570 won, cefuroxime tid-azithromycin group for the 251,700 won. There was no significant statistical difference in clinical, bacterial, radiological cure and hospital days, and switch to oral days. In conclusion, that i.v. moxifloxacin monotherapy was as effective as azithromycin plus cefuroxime or ceftriaxone combination therapies fur the treatment of CAP. In drug cost analysis, moxifloxacin is less expensive than CAG.

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The relationship between the major market-based media and the government in Korea (한국의 민주화와 미디어 : 정부와 시장 주류 미디어의 관계)

  • Jo, Hang-Je
    • Korean journal of communication and information
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    • v.16
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    • pp.168-206
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    • 2001
  • This study attempts to examine the relationships between the major market-based media and the government after closing military regime era, 1961-1987. After the military regime was collapsed, while the mass media in Korea obtained independence and autonomy from government, they have been confronted with the terrible competition not so much comparatively as before. The watchdog role in the traditional liberalism, which is regarded as normative relationship between the media and the government would be transformed in accordance with the market condition and the maturity of democracy. Thus, the watchdog metaphor has been variously deviated in rower-centered society; lap dog, guard dog, attack dog. liberalists argue that the primary democratic role of the media is to art as a public watchdog overseeing the state. Social democrats, however, criticize them as simplistic conception which could be only applied to the government. They argue that the media should be seen as a source of redress against the abuse of all forms of power over others; the home, the economy, and the civil society. The lap dog view is that the media is overwhelmingly dependent on the established power structure contrary to the watchdog. While the guard dog perspective is a means to preserve the power structure alarming with playing 'conflict role', the attack do8 aims to the private interest of the media in intruding into the politics. The attack dog perspective by T. Patterson could be composed of the interpretive style of report, the game schema report over the policy schema in the election, and the negativism against politics and government. The market-dominant press has been likely to transform from lap-guard dog into attack-guard dog. In Roh Tae Woo government(1988-1992), while the press was a lessened lap-guard dog before three parties merger in 1990, after merger the press had been transformed as the reinforced lap-guard dog because this merger entailed joint, party-to-party negotiations, and the formation of the new party preceded by dissolution of the ruling blot. In the early stage of Kim Young Sam government(1993-1997), the press has kept in pace with the reform movement drive-forced by the government. However, the press withdrew the support of Kim's reform in reaching the level of threat to ruling bloc. The press coalesced only circumstantially with government and was interested in preserving some margin of independence. The failure of Kim's reform proved the political muscle of the press in post-autho-ritarianism. In the middle stage of Kim Dae Jung government (1998-) that resulted in the shift of power structure as once-opposition party leader, the stress has been a manifested attack-guard dog owing to the anti-cold war policy, the realignment policy of power, and the minority-base of Kim's government. The press has endeavored to hold political communication within limits relatively less threatening to the established order.

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Type of Subjective Perception on the Fear Message - Q-methodological analysis on the latest Report of Korean Peninsula Situation - (위협적 메시지에 대한 주관적 인식 유형 - 최근 한반도 정세 관련 보도의 Q방법론적 분석 -)

  • Lee, Soonmo
    • Journal of Information Technology and Architecture
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    • v.10 no.2
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    • pp.223-236
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    • 2013
  • Related to the situation on the Korean Peninsula, by North Korea's threat of war the tension escalates and serious crisis continues. The purpose of this study is to evaluate the subjective perception which the residents of South Korea feel about North Korea's threat of war through a Q methodological analysis framework. In the result of the study, for the North Korea's threat of war the South Korean's recognition type is analyzed into four type such as 'non-reactive', 'fearreactive', 'psychological anxiety' and 'cynical ignorance type'. First, the No. 1 type 'non-reactive' does not empathize with North Korea's threat of war itself, and second type 'fear-reactive' have uneasy feeling like that 'What would happen as things go' and feel a sense of crisis about the North Korea's threat of war. The third type 'psychological anxiety' is type which feels that due to North Korea's threat of war inter-Korean relations is in the crisis. Finally the fourth type 'cynical ignorance' think that North Korea's threat of war is bluffing and also North Korea is like a shepherd boy. The reason to apply Q-methodology in this study is to make it possible to a more in-depth approach to subjective perception and threat of psychological meaning for the threatening message of study participants.

Filed Applicability Evaluations of Restoration Material for Underground Cavities Formed by Ground Subsidence (지반침하로 인한 지하공동 복구재료의 현장적용성 평가)

  • Bang, Seongtaek;Baek, Seungju
    • Journal of the Korean GEO-environmental Society
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    • v.21 no.3
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    • pp.5-11
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    • 2020
  • Recently, ground pits that have been occurring frequently in urban areas are hindering traffic flow and causing property damages and loss of human life, acting as factors that are threatening the safety of citizens. Therefore, sunken ground must be quickly restored and provisions must be made for additional damage but current domestic detailed standards regarding ground pits and accurate definitions regarding causes and measures to be taken for reoccurrences are lacking. Restoration methods of sunken ground include backfilling by reusing sunken soil or other fill material and paving the road and while this is the most often used method, this only prevents ground from sinking temporarily and can not serve as a fundamental solution. Also, additional ground pits can occur on ground that is reinforced using this method due to faulty backfill material or faulty hardening. This study used Eco-friendly High-Strength Material (EHSM) as restoration material that can be used in the restoration of underground cavities that have occurred due to ground subsidence to analyze the engineered characteristics of modified dredging clay and test pieces made from changed ratios of EHSM and weathered granite soil were uniaxial compression tests were conducted and freezing-thawing tests were conducted to study strength properties according to environmental changes of restoration material, and after tests were concluded by each level, uniaxial compression tests and dynamic elasticity tests were conducted for intensity analysis. Also, to evaluate strength characteristics of the restored ground, dynamic plate load tests were conducted to verify the improvement effectiveness of the restored ground.

Two Cases of Tension Pneumopericardium in Mechanically Ventilated Preterm Infants (미숙아에서 인공호흡기 치료 중 발생한 긴장성공기심장막증 2예)

  • Maeng, Se-Hyun;Seo, Hyun-Joo;Shin, Jeong-Hee;Jung, Ji-Mi;Kim, Jin-Kyu;Yoo, Hye-Soo;Ahn, So-Yoon;Kim, Eun-Sun;Chang, Yun-Sil;Park, Won-Soon
    • Neonatal Medicine
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    • v.18 no.1
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    • pp.153-157
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    • 2011
  • Pneumopericardium is a rare form of neonatal air leakage. Tension pneumopericardium is much more infrequent, but can cause a cardiovascular deterioration with high mortality up to 80% and neurodevelopmental morbidity in half of the cases. We report two cases of preterm infants who successfully recovered from tension pneumopericardium that developed during mechanical ventilator assistance. The patients displayed a sudden increase in oxygen demand and subsequent cardiovascular deterioration. Immediate needle aspiration of the pneumopericardium performed after checking X-ray images rescued each of patient. Since the clinical symptoms are non-specific, clinicians' suspicion is most important when patients show sudden refractory cardiovascular collapse, especially in ventilator-assisted neonates. This life threatening complication demands instant diagnosis and intervention.

Dispersion Pattern Simulation of Tungsten Impactors According to Mass and Shape of Explosives (폭약 질량과 형상에 따른 텅스텐 충격자의 분산 패턴 시뮬레이션)

  • Sakong, Jae;Woo, Sung-Choong;Bae, Yong-Woon;Choi, Yeoun-Jin;Cha, Jung-Phil;Ga, In-Han;Kim, Tae-Won
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.38 no.12
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    • pp.1325-1333
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    • 2014
  • The dispersion pattern of a near miss neutralizer has a great effect on the disablement of a threatening projectile. This study numerically investigated the dispersion pattern of cylindrical tungsten impactors by an explosion in the near miss neutralizer. The mass and shape of the explosive were considered as influencing factors on the dispersion pattern. The explosives were set using two shape models: a parallel shape with the same upper and lower thicknesses and a tapered shape with different upper and lower thicknesses. In the simulation results, the dispersed impactors formed a ring-shaped pattern on a two-dimensional plane in an arbitrary space. In addition, the fire net area increased with the explosive mass when the explosive shapes were identical. In particular, the tapered shape explosive formed a larger fire net area than the parallel shape explosive. Based on the analysis of the fire net area along with the dispersion density, both the explosive mass and shape representing the physical characteristics should be considered for controlling the dispersion pattern of impactors in a near miss neutralizer.

A Study on the Customers' Awareness for Modernizing the Facilities of Traditional Market (재래시장 시설현대화에 따른 소비자 인식도에 관한 연구 - 목포지역 소비자들을 대상으로 -)

  • Kim, Pan-Jin;Kim, Kyeong-Cho;NamKoong, Seok;Youn, Myoung-Kil
    • Journal of Distribution Science
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    • v.7 no.1
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    • pp.55-70
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    • 2009
  • There is under restructuring of whole distribution market in Mokpo recently. Large-Scale Discount Stores such as E-mart, Lotte Mart, Homeplus and Nonghyup Hanaro Mart entered successfully in the distribution environment in Mokpo. However, the small and medium distributors are falling rapidly, and traditional market is depressed. This status gives some positive effects to make one-stop, good price, good quality and great variety of shopping for saving the time and effort through changing the customers' life-style. This change, however, made the traditional market worse that played as the core channel for trading the local special products and an important role for local economic in retailing market. It is a threatening factor for that traditional market to recover the recession. The decline of traditional market and the bankruptcy of small retailing dealers accelerate the stagnation of local economic and commercial power. Therefore, it need a systematic and synthetical study to solve the negative factors for improving life of the local resident. This paper looked into the concept, issues and development strategy of traditional market that affect local economic development directly. It studied the customers' awareness for traditional market that was recently modernized the facilities in Mokpo. Particularly, based on the research material that was published last academic symposium, it looked about the issues and development strategy that could happen in traditional market not the market of a specific region but all over the country. Therefore, the purpose of this paper is that the central and local government and retailers get a help to make the efficient and useful development strategy through analyzing the effects of customers for modernizing the facilities of traditional market.

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Overcoming the Discourse of Foreignness: A Study on Class Positionality and Dual Identity of Korean Housemaids and Korean-Chinese Domestic Workers (외국인 담론 극복하기: 식모와 조선족 입주 가사노동자의 계급적 위치성과 이중적 정체성에 관한 연구)

  • Park, Soyoung
    • Journal of the Korean Geographical Society
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    • v.50 no.2
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    • pp.185-201
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    • 2015
  • This paper suggests how Korean housemaids, called Sikmo, and Korean-Chinese migrant domestic workers have similar class positions and therefore form a dual identity in their interactions with female employers. rough spoken stories of the experiences of 27 females from Seoul, including Korean-Chinese domestic workers, Korean housemaids, and their employers, this research effectively overcomes the dichotomous discourse of natives versus foreigners. Instead it suggests the new interpretation that it is not foreignness but class inferiority of the domestic workers that plays a key role in establishing relationships with employers. Korean housemaids and Korean-Chinese domestic workers, both groups of whom are migrant workers, have developed coping strategies to enhance their labor value by spatially relocating themselves from their home society to a new society. They possess a similar labor status in women's history, being of low income, low education, and rural births. Consequently, these women experience 'translocal anchoring,' meaning their identities are intertwined with that of their home societies, and employers perceive them based on the characteristics of these places. The Korean employers perceive that the domestic workers' morality and intellectuality are inferior based on their class differences. This stigmatizing process leads employers to regard domestic workers as ambivalent people, not only threatening outsiders but also objects of pity, needing love and protection of their employers. The employers educate them culturally, teaching them skills to survive in the urban environment. These skills include cooking and language, in addition to advice on long-term plans to blend into society.

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Comparative Genomic Analysis of Staphylococcus aureus FORC_001 and S. aureus MRSA252 Reveals the Characteristics of Antibiotic Resistance and Virulence Factors for Human Infection

  • Lim, Sooyeon;Lee, Dong-Hoon;Kwak, Woori;Shin, Hakdong;Ku, Hye-Jin;Lee, Jong-eun;Lee, Gun Eui;Kim, Heebal;Choi, Sang-Ho;Ryu, Sangryeol;Lee, Ju-Hoon
    • Journal of Microbiology and Biotechnology
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    • v.25 no.1
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    • pp.98-108
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    • 2015
  • Staphylococcus aureus is an important foodborne pathogen that causes diverse diseases ranging from minor infections to life-threatening conditions in humans and animals. To further understand its pathogenesis, the genome of the strain S. aureus FORC_001 was isolated from a contaminated food. Its genome consists of 2,886,017 bp double-stranded DNA with a GC content of 32.8%. It is predicted to contain 2,728 open reading frames, 57 tRNAs, and 6 rRNA operons, including 1 additional 5S rRNA gene. Comparative phylogenetic tree analysis of 40 complete S. aureus genome sequences using average nucleotide identity (ANI) revealed that strain FORC_001 belonged to Group I. The closest phylogenetic match was S. aureus MRSA252, according to a whole-genome ANI (99.87%), suggesting that they might share a common ancestor. Comparative genome analysis of FORC_001 and MRSA252 revealed two non-homologous regions: Regions I and II. The presence of various antibiotic resistance genes, including the SCCmec cluster in Region I of MRSA252, suggests that this strain might have acquired the SCCmec cluster to adapt to specific environments containing methicillin. Region II of both genomes contains prophage regions but their DNA sequence identity is very low, suggesting that the prophages might differ. This is the first report of the complete genome sequence of S. aureus isolated from a real foodborne outbreak in South Korea. This report would be helpful to extend our understanding about the genome, general characteristics, and virulence factors of S. aureus for further studies of pathogenesis, rapid detection, and epidemiological investigation in foodborne outbreak.

A case of imipramine induced toxicity with Brugada electrocardiographic pattern in a toddler (Brugada 심전도 양상을 포함한 이미프라민에 의한 독성 부작용 1예)

  • Choi, Woo-Yeon;Park, Soo-Min;Han, Ui-Jeong;Kim, Young-Nam;Cho, Young-Kuk;Ma, Jae-Sook
    • Clinical and Experimental Pediatrics
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    • v.51 no.11
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    • pp.1232-1235
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    • 2008
  • Imipramine, a tricyclic antidepressant (TCA), is used for the treatment of non-polar depression and nocturnal enuresis in children in whom an organic pathology has been excluded, anxiety disorders, and neuropathic pain. Clinical toxicity following the treatment of TCAs, including imipramine, is well known. The anticholinergic effects initially present include a dry mouth, ileus, dilated pupils, urinary retention, and mild sinus tachycardia. The central nervous system toxicity includes delirium, agitation, restlessness, hallucinations, convulsions, and CNS depression or coma. However, the most life-threatening toxicity remains the development of cardiac dysrhythmias. Conduction delays such as QRS and corrected QT prolongation, wide QRS complex tachycardia, and the Brugada electrocardiographic pattern have been reported. Sodium bicarbonate decreases QRS widening and suppresses dysrhythmias by providing excess sodium to reverse the TCA-induced sodium-channel blockade and possibly by binding directly to the myocardium. There are no pediatric case reports on imipramine or other TCA associated toxicity in Korea. Here, we describe a patient who presented with convulsions, tachycardia with a wide QRS complex, a Brugada electrocardiographic pattern, and anuresis associated with an accidental overdose of imipramine and the outcome of treatment with sodium bicarbonate.