• Korean Journal of Poultry Science
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• v.35 no.1
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• pp.15-20
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• 2008

This study aimed at evaluating the effects of a molting diet method in molt induction and post-molt performance of laying hens. Eighty-one ISA Brown hens at 62 wk of age were randomly divided into three groups. After a 4-wk preliminary period, a control group was fed a corn-soybean-based layer diet, and for the other groups, molting was induced by starvation (MS) or feeding a molting diet (MD). For the MS group, feed was withdrawn for 2 wk; this was followed by feeding a layer diet every other day for 1 wk and then the control diet. The MD group was fed a molting diet containing low-protein and low-energy diet based for 4 wk; this was followed by feeding a layer diet. They had a free access to their diet and water. Egg production, egg quality, feed intake, and ovary and oviduct weights were measured throughout the experimental period. During molting, the feed intake in the MD group was lower than that of the control. Body weight of the molted groups was significantly reduced. The MS group feeding totally ceased egg production within 4d; after the initiation of feeding and decreased; in the MD group, egg production to 9.3% by d 10. On d 14, the ovaries and oviducts of the molted groups were distinctly lighter than those of the control. Throughout the post-molt period, egg production and egg shell thickness of the molted group improved; but there were no significant differences. Eggs from the MD-fed or control group were heavier than those of the MS-fed or control group. Finally, feeding of a low-protein and low-energy diet effectively induces molting and increase post-molt production, but further research will be conducted to determine the effects of the molt diet with other ingredients and to reduce the energy level of the molt diet for maximizing molt induction and post-molt egg quality.

• Korean Journal of Poultry Science
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• v.34 no.1
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• pp.37-42
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• 2007

This study was conducted to investigate the effects of graded levels of a herbal recipe(Herb Mix $Gold^{(R)}$, Herb BIO Co.) supplemented to a commercial layer diet. The Herb Mix $Gold^{(R)}$ is an improved recipe of Herb $Mix^{(R)}$, fortified with Angelica gigas, Discorea japonica and Ligusticum jeholense. A total of 720 layers (Hy-Line Brown) of 45 wks old were assigned to one of six treatments; control, 0.2% Herb $Mix^{(R)}$, 0.1%, 0.2%, and 0.3% Herb Mix $Gold^{(R)}$, and 6 ppm Avilamycin. Each treatment had 6 replicates of 20 birds each housed in 2 birds cages. Birds were fed diets and water ad libitum for 5 weeks. Hen-day egg production was significantly (P<0.05) different among treatments. Herb Mix $Gold^{(R)}$ 0.2% treatment showed the highest egg production followed by Herb Mix $Gold^{(R)}$ 0.3%, Herb $Mix^{(R)}$ 0.2%, Herb Mix $Gold^{(R)}$ 0.1%, Avilamycin 6 ppm and the control. Hen-housed egg production, egg weight, soft and broken egg ration, feed intake, feed conversion ratio, shell strength, shell thickness, shell color index, Haugh unit and yolk color index were not significantly different among treatments. Nor was cfu of Cl. perfringens and E. coli and Lactobacilli in the small intestinal content significantly different among treatments. The number of white and red blood cells, hemoglobin, heterophil, lymphocyte, thus heterophil to lymphocyte ratio were not significantly modified. It was concluded that Herb Mix $Gold^{(R)}$ at the level of 0.2% in the layer diet improves laying performance.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.23 no.2
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• pp.27-40
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• 2010

Background and Objective : Increasing interest in anti-aging and anti-wrinkling agents for the skin has triggered the recent outflow of researches and studies in this field. This study was designed to investigate the effects of bee venom on skin wrinkling and skin aging by testing the skin wrinkling, skin elasticity, trans-epidermal water loss (TEWL), free radical level, anti-oxidative agent level, and skin tissue after infusion of bee venom on hairless mouse. Materials and Methods : Fifteen hairless mice aged between 36~40 weeks were divided randomly into 3 Group; the Bee Venom Syringe Group, the Bee Venom Needle Group, and the control group. The Bee Venom Syringe Group were injected subcutaneously with bee venom (0.1cc in total) using an insulin syringe on three spots in the lumbar spine (one spot on the center and two spots 1~2cm to the side bilaterally). The Bee Venom Needle Group were pricked with bee venom-smeared acupuncture needles on three longitudinal spots in the lumbar spine each 1cm apart, after which the needles were removed 10 minutes later. The Control Group did not receive any form of intervention. All procedures took place thrice a week for four weeks, during which the mice were allowed free access to water and fodder. The mice were measured and compared in the weight, skin wrinkling scale, skin elasticity, and TEWL before and after the experiment. After the experiment, blood samples were taken to measure the free radical and anti-oxidative agent level, and the skin tissue was sliced for examination. Data was analyzed using the SPSS program (ver 12.0). The ANOVA analysis was used to compare and contrast the three groups, and t-test for paired samples was used to evaluate skin-wrinkling before and after experiment. The cut-off p-value of significance was set at p<0.05. Results : 1. Administration of bee venom did not cause serious weight loss or gain. 2. Compared to the control group, the Bee Venom Syringe Group and the Bee Venom Needle Group both showed a decrease in skin wrinkling scale after intervention. Especially, the Bee Venom Syringe Group showed a significant decrease (p<0.05). 3. Compared to the control group, the Bee Venom Syringe Group and the Bee Venom Needle Group both showed an increase in skin elasticity. Especially, the Bee Venom Syringe Group showed a significant increase (p<0.05). 4. No significant change in TEWL was found in the mice in all the three groups before and after experiment. 5. Free radical level was normal in all 15 mice in all the three groups, and anti-oxidative agent was not significantly different across the three groups. 6. The Bee Venom Syringe Group, the Bee Venom Needle Group, and the control group did not show any significant difference in the thickness of epidermis and dermis, infiltration of inflammatory cells, and skin wrinkling. The epidermis layer was relatively better preserved in the Bee Venom Syringe Group as compared to the Bee Venom Needle Group and the control group. Conclusion : Direct injection of bee venom on the hairless mouse using a syringe was found to improve wrinkling of the skin and increase skin elasticity but did not show effectiveness on skin dryness due to water loss. The bee venom appears to have suppressive effects on skin wrinkling, one of the symptoms of skin aging, through a process independent of suppression of free radicals or increase of anti-oxidative agent.

• The Journal of Engineering Geology
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• v.17 no.4
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• pp.601-613
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• 2007

It is reported that factors affecting the behavior of reinforced earth retaining walls built on soft ground are not only basic physical properties but also the increase of load by the reinforced earth retaining walls, consolidation period, pore water pressure, etc. This study analyzed the behavior of reinforced earth retaining walls and soft ground using SAGE CRISP, a ground analysis program. First, we examined the effect of the replacement method, which was to prevent the excessive displacement of reinforced earth retaining walls, in improving the behavior of the walls. Second, we compared and analyzed how the behavior of ground is affected by the vertical interval of stiffeners on the back of reinforced earth retaining walls after the application of the replacement method. Lastly, we proposed the optimal replacement width and depth in the application of the replacement method. The results of this study proved that the replacement method is considerably effective in improving the behavior of reinforced earth retaining walls. In addition, the vertical interval of stiffeners on the back of reinforced earth retaining walls appeared effective in improving the horizontal displacement of the top of retaining walls but not much effective in improving the vertical displacement of the back of retaining walls. In addition, improvement in horizontal-vertical displacement resulting from the increase in replacement width was not significant and this suggests that the increase of replacement width is not necessary. With regard to an adequate replacement depth, we proposed the ratio of replacement depth to the height of retaining walls(D/H) according to the ratio of the thickness of the soft layer to the height of retaining walls(H/T).

• Proceedings of the Korea Technical Association of the Pulp and Paper Industry Conference
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• 2007.04a
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• pp.380-390
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• 2007

The purpose of this study is to make a functional Hanji treated with an oriental lacquer which has various functionalities. The raw oriental lacquer produced in China was used in this study This lacquer was diluted with ethanol and terpene in different solvent ratios. The diluted lacquer in the solvents had two layers. The upper layer was solvent soluble and the lower contained precipitates. Hanji was treated with the solvent solubles and the mixture containing precipitates, and then properties of the Hanji were evaluated. The oriental lacquer consisted of 25.04% of water, 60% of urushiol, 3.13% of nitrogen-containing compounds, and 5.66% of gum. The pH of oriental lacquer was 5.3 and the viscosity was 1680 cP. The average weight, thickness, and density of Hanji treated with oriental lacquer tended to gradually decreased as the lower concentration of lacquer was used and as the solvent soluble was treated. Tensile strength of the treated Hanji decreased when the diluted lacquer was used and Hanji treated with terpene dilutes at the ratio of lacquer to solvent of 1:5 (v/v) showed higher tensile strength than ones treated with ethanol dilutes. The folding endurance decreased as the less concentrated lacquer was used and the highest value was obtained when 1:40 (v/v) of lacquer to solvent ratio in both ethanol and terpene mixture. Absorption ratio was higher in the Hanji treated with ethanol mixture, treated with the lacquer in higher concentration, and treated with ethanol mixture. Hanji treated with ethanol dilutes at 1:20 (v/v) and the lower ratio of lacquer to solvent showed a hydrophobic property. Amount of the bound dye materials tended to be decreasing as the concentration of lacquer becomes lower and it was higher in Hanji treated with ethanol mixture than with terpene mixture. Color of Hanji treated with the solvent diluted mixture was Y to YR-type, whereas that of Hanji treated with raw oriental lacquer was Y-type, terpene

• Journal of Dental Rehabilitation and Applied Science
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• v.23 no.4
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• pp.283-292
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• 2007

Two-step or one-step bonding systems generally inhibit curing process of dual-cured core build-up resin composite for their adhesive acidity. In addition this dual-cured core build-up resin composite can be applied to dentin of pulp chamber and root at the time that complete the endodontic treatment. The purpose of this investigation was to determine the influence of sodium hypochlorite on rnicrotensile bond strength of dual-cured core build-up resin composite. Extracted human molars were horizontally sectioned with 1mm thickness using low speed diamond saw. After the sectioned specimens were divided into 8 groups, adhesive systems (Clearfil SE-Bond, Prime&Bond NT[2-step, 1-step], Adper Prompt L-Pop) were then applied with or without sodium hypochlorite pretreatment. The treated specimen was filled with dual-cured core build-up resin composite (Luxacore, DMG corp., German). Then light cured for 40 seconds and soaked in $37^{\circ}C$ water bath for 24 hours. After the treated specimen was grinded with 1mm width and measured rnicrotensile bond strength by testing machine. Additionally 8 teeth were prepared for SEM evaluation. The results were as follows. : NaOCl treated groups generally had lower rnicrotensile bond strength but did not show any difference statistically except Adper Prompt L-Pop. When the teeth were treated by NaOCl, though the difference of applied adhesive system, it had no statistically significant difference within the NaOCl treated groups except the relation of between ClearFil SE-Bond adhesive system and Adper Prompt L-Pop adhesive system. In the SEM evaluation, NaOCl treated groups presented relatively long resin tags and incomplete hybrid layer formation generally.

• Membrane Journal
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• v.28 no.1
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• pp.21-30
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• 2018

In this study, homogeneous and defect-free ceramic ultrafiltration membranes were fabricated by using the sol-gel method. A boehmite sol was synthesized and coated onto the surface of alumina hollow fiber microfiltration membranes. The effect of sol viscosity and surface tension on the coating layer homogeneity and thickness was investigated. The optimum coating repetition using pristine sol was determined to be 3 times, as the samples coated more than 4 times showed delamination. Fixing the coating repetition to 3 times, the effect of sintering temperature was also studied in this work. The samples sintered at $1000^{\circ}C$ exhibited the highest pure water permeability with the molecular weight cut-off (MWCO) of approximately 51 kDa (10 nm dextran), and the samples sintered at 600, $800^{\circ}C$ displayed the MWCO of 12 kDa (5 nm dextran). The ultrafiltration membranes prepared in this work showed competitive performance compared to the reported ceramic ultrafiltration membranes.

• Journal of Pharmaceutical Investigation
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• v.35 no.6
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• pp.417-422
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• 2005

This study was aimed to design and formulate the moisture-activated patches containing ofloxacin and lidocaine for antibacterial and local anesthetic action. The solubility of lidocaine at $32^{\circ}C$ in various vehicles decreased in the rank order of PG $759.5{\pm}44.5\;mg/mL$ > PGL > IPM > PEG 300 > PEG 400 > Ethanol > PGMC > DGME > PGML > OA > $Captex^{\circledR}\;300$ > $Captex^{\circledR}\;200$ > water $(4.0{\pm}0.1\;mg/mL)$. Ofloxacin revealed very low solubility, which the highest solubility was obtained from PEG 400 $(18.7{\pm}6.3\;mg/mL)$ among the vehicles used. The addition of lactic acid increased the solubility of ofloxacin dramatically; the solubility at 5% lactic acid was $133.7{\pm}9.7\;mg/mL$. As $2-hydroxypropyl-{\beta}-cyclodextrin$ was added at the concentrations of 40, 80, 120, 160 and 200 mM, the solubilities of lidocaine and ofloxacin were enhanced up to three and two times, respectively, with concentration-dependent pattern. Gel intermediates for filmtype patches were prepared with mucoadhesive polymer, viscosity builders, lidocaine or ofloxacin at pH values from 5 to 7. Gels were cast onto a release liner and dried at room temperature. Dried patch was attached onto an adhesive backing layer, thus forming a patch system. Patches containing a single drug component were characterized by in vitro measurement of drug release rates through a cellulose barrier membrane. The release study was carried out at $37^{\circ}C$ using a Franz-type cell. Receptor solutions were isotonic phosphate buffers (pH 7.4). Samples $(100\;{\mu}L)$ were taken over 24 hours and quantitated by a verified HPLC method. The releases from all tested were proportional to the square root of time. The release rates were 0.9, 157.3 and $281.7\;{\mu}g/cm^{2}/min^{1/2}$ for the lidocaine patches and 19.8,37.2 and $50.7\;{\mu}g/cm^{2}/min^{1/2}$ for the ofloxacin patches at the concentrations of 0.3, 0.5 and 1 %, respectively. The release rates were dose dependent in both drug patches $(R^{2}\;=\;0.9077\;for\;lidocaine;\;R^{2}\;=\;0.9949\;for\;ofloxacin)$ and those were also thickness-dependent $(R^{2}\;=\;0.9246\;for\;lidocaine;\;R^{2}\;=\;0.9512\;for\;ofloxacin)$.

• The Journal of Engineering Geology
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• v.11 no.2
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• pp.175-190
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• 2001

This study investigates the existing theoretical backgrounds in order to examine the behavior of lateral flow according to the plasticity of soils when unsymmetrical surcharge is worked on polluted soft soils by comparing and analyzing the results measured through model tests. Model tests are canied out as follows soil tank, bearing frame and bearing plate are made. By increasing unsymmetrical surcharge to the ground soils with the consistent water content and with gradually increased polluted materials at intervals, the amounts of settlement, lateral displacement and upheaval were respectively observed. In conclusion, the value of critical surcharge was expressed as q$_{cr}$=2.78$_{cu}$ which was similar to those Tschebotarioff(q$_{cr}$=3.0$_{cu}$) and Meyerhof(q$_{cr}$=(B/2H+$\pi$/2)$_{cu}$) had been proposed. The value of ultimate capacity was expressed as q$_{ult}$=4.84$_{cu}$ which was similar to that of Prandtl. The lateral flow pressure is adeQuately calculated by the eQuation(P$_{max}$=K$_o$ r H) and the maximum value of lateral flow pressure is found near O.3H of layer thickness(H) and is higher to ground surface than the ones in composition pattern, Poulos distribution pattern and softclay soils (CL, CH) which is not polluted. The stability control method used in this research followed the management diagram of Tominaga.Hashimoto, Shibata.Sekiguchi, Matsuo.Kawamura who use the amounts of plasticity displacement by lateral flow. As a result, the ultimate capacity values in the diagram {S$_v$-(Y$_m$/S$_v$)} of Matsuo.Kawamura and in the diagram {(q/Y$_m$)-q} of Shibata. Sekiguchi were smaller than in the ones of load-settlement curve (q-S$_v$).

• Geophysics and Geophysical Exploration
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• v.10 no.1
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• pp.50-59
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• 2007

The advent of towed geo-electrical array surveying on water and land has resulted in datasets of magnitude approaching that of airborne electromagnetic surveying and most suited to 1D inversion. Robustness and complete automation is essential if processing and reliable interpretation of such data is to be viable. Sharp boundaries such as river beds and the top of saline aquifers must be resolved so use of smoothness constraints must be minimised. Suitable inversion algorithms must intelligently handle low signal-to-noise ratio data if conductive basement, that attenuates signal, is not to be misrepresented. A noise-level aware inversion algorithm that operates with one elastic thickness layer per electrode configuration has been coded. The noise-level aware inversion identifies if conductive basement has attenuated signal levels so that they are below noise level, and models conductive basement where appropriate. Layers in the initial models are distributed to span the effective depths of each of the geo-electric array quadrupoles. The algorithm works optimally on data collected using geo-electric arrays with an approximately exponential distribution of quadrupole effective depths. Inversion of data from arrays with linear electrodes, used to reduce contact resistance, and capacitive-line antennae is plausible. This paper demonstrates the effectiveness of the algorithm using theoretical examples and an example from a salt interception scheme on the Murray River, Australia.