• Nutrition Research and Practice
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• v.8 no.5
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• pp.526-532
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• 2014

BACKGROUND/OBJECTIVES: Acanthopanax sessiliflorus is a native Korean plant and used as a traditional medicine or an ingredient in many Korean foods. The free radical theory of aging suggests that cellular oxidative stress caused by free radicals is the main cause of aging. Free radicals can be removed by cellular anti-oxidants. MATERIALS/METHODS: Here, we examined the anti-oxidant activity of Acanthopanax sessiliflorus extract both in vitro and in vivo. Survival of nematode C. elegans under stress conditions was also compared between control and Acanthopanax sessiliflorus extract-treated groups. Then, anti-aging effect of Acanthopanax sessiliflorus extract was monitored in C. elegans. RESULTS: Stem extract significantly reduced oxidative DNA damage in lymphocyte, which was not observed by leaves or root extract. Survival of C. elegans under oxidative-stress conditions was significantly enhanced by Acanthopanax sessiliflorus stem extract. In addition, Acanthopanax sessiliflorus stem increased resistance to other environmental stresses, including heat shock and ultraviolet irradiation. Treatment with Acanthopanax sessiliflorus stem extract significantly extended both mean and maximum lifespan in C. elegans. However, fertility was not affected by Acanthopanax sessiliflorus stem. CONCLUSION: Different parts of Acanthopanax sessiliflorus have different bioactivities and stem extract have strong anti-oxidant activity in both rat lymphocytes and C. elegans, and conferred a longevity phenotype without reduced reproduction in C. elegans, which provides conclusive evidence to support the free radical theory of aging.

• Journal of Korean Medical classics
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• v.34 no.3
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• pp.101-123
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• 2021

Objectives : To examine the six positions correlation[六部定位] principle that is the basis of the wrist pulse diagnosis in the Neijing. Methods : The basis for argument was established by correcting an interpretation error of the theory of chi (尺) skin diagnosis. In order to accomplish this, the annotations of Yang Shangshan and Wangbing were investigated first, after which the specific meaning and methodology of the chi diagnostic method as written in many chapters of the Neijing were examined. The evidence and reasoning for the six positions correlation[六部定位] was looked into, in relation to Wangbing's annotation of the chapter, Maiyaojingweilun. The theoretical basis of the six positions correlation was searched throughout the entire Neijing, based on the correlation between Liuhe and the six positions, the five elements inter-supporting theory embedded in the six positions correlation as a diagnosis model that integrates zhangfu and meridians/channels, and the meaning of the spacial concepts used when describing the tactile technique within the chapter. Lastly, contents related to the five zhang channels within the Neijing were reviewed, to determine whether the six positions correlation was applied in wrist pulse taking Results & Conclusions : Some interpretations of the verse on matching the positions in the Maiyaojingweilun chapter of the Neijing are erroneous, while the argument that the three positions[cun-guan-chi] cannot be found in the Neijing is false as well. The wrist pulse taking in the Neijing is precisely based on the three positions correlation that divides the cun-guan-chi positions into three, and the correlation verse in the Maiyaojingweilun chapter clearly suggests the principle of matching the zhangfu and meridian/channels to the six positions of the cun-guan-chi of both left and right.

• The Journal of Korean Medicine
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• v.45 no.1
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• pp.1-16
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• 2024

Introduction: The importance of clinical skills training in traditional Korean medicine education is increasingly emphasized. Since the clinical skills tests are high-stakes tests that determine success in national licensing exams, it is essential to develop reliable multifaceted analysis methods for clinical skills tests in actual education settings. In this study, we applied the multifaceted validity evaluation methods to the evaluation results of the cardiopulmonary resuscitation module to confirm the applicability and effectiveness of the methods. Methods: In this study, we used internal consistency, factor analysis, generalizability theory G-study and D-study, ANOVA, Kendall's tau, descriptive statistics, and other statistical methods to analyze the multidimensional validity of a cardiopulmonary resuscitation test in clinical education settings over the past three years. Results: The factor analysis and internal consistency analysis showed that the evaluation rubric had an unstable structure and low concordance. The G-study showed that the error of the clinical skills assessment was large due to the evaluator and unexpected errors. The D-study showed that the variance error of the evaluator should be significantly reduced to validate the evaluation. The ANOVA and Kendall's tau confirmed that evaluator heterogeneity was a problem. Discussion and Conclusion: Clinical skills tests should be continuously evaluated and managed for validity in two steps of pre-production and actual implementation. This study has presented specific methods for analyzing the validity of clinical skills training and testing in actual education settings. This study would contribute to the foundation for competency-based evidence-based education in practical clinical training.

• Journal of Electrical Engineering and Technology
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• v.10 no.4
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• pp.1540-1551
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• 2015

The detection of position and speed in BLDC motors without using position sensors has meant many efforts for the last decades. The aim of this paper is to develop a sensorless technique for detecting the position and speed of BLDC motors, and to overcome the drawbacks of position sensor-based methods by improving the performance of traditional approaches oriented to motor phase voltage sensing. The position and speed information is obtained by computing the derivative of the terminal phase voltages regarding to a virtual neutral point. For starting-up the motor and implementing the algorithms of the detection technique, a FPGA board with a real-time processor is used. Also, a versatile hardware has been developed for driving BLDC motors through pulse width modulation (PWM) signals. Delta and wye winding motors have been considered for evaluating the performance of the designed hardware and software, and tests with and without load are performed. Experimental results for validating the detection technique were attained in the range 5-1500 rpm and 5-150 rpm under no-load and full-load conditions, respectively. Specifically, speed and position square errors lower than 3 rpm and between 10º-30º were obtained without load. In addition, the speed and position errors after full-load tests were around 1 rpm and between 10º-15º, respectively. These results provide the evidence that the developed technique allows to detect the position and speed of BLDC motors with low accuracy errors at starting-up and over a wide speed range, and reduce the influence of noise in position sensing, which suggest that it can be satisfactorily used as a reliable alternative to position sensors in precision applications.

• Journal of Korea Society of Industrial Information Systems
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• v.22 no.6
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• pp.71-84
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• 2017

Over the past decade, we have witnessed Serious Debates in MISQ and Other Journals Between Two Camps that have Differing Views on the use of Causal Indicators to Measure Constructs. There is the Camp that advocates Causal Indicators (ADVOCATE) and the Camp that opposes Their Usage (OPPONENT). The Debates have been primarily centered on the OPPONENT's Argument that the Meaning of a Latent Variable is determined by its Outcome Variables. However, Little Effort has been made to Validate the ADVOCATE's Dispute (Against the OPPONENT's Arguments) that the Meaning of a Latent Variable is decided by its Causal Indicators if there is no Misspecification. Our Study precisely examines the Integrity of the Argument. For this, we empirically examine how the two Primary Psychometric Properties-Comprehensiveness and Interrelationship-of Causal Indicators Influence Theory Testing between Latent Variables through Three Different Tests (i.e., Comprehensive Test, Interrelationship Test, and Mixed Test). Conducted on Two Different Datasets, Our Analysis Consistently Reveals that Structural Path Coefficients are Hardly Sensitive to the Changes (i.e., Misspecification) in the Properties of Causal Indicators. The Discovery offers Important Evidence that the Sound Theoretical Logic of a Causal Model is not in Sync with the Empirical Mechanism of Parameter Estimation. This Underscores that a Latent Variable Formed by Causal Indicators is empirically an elusive notion that is Difficult to Operationalize. As Our Results have Significant Implications on the Integrity of Numerous IS studies which have conducted Theory or Hypothesis Testing Using Causal Indicators, we strongly advocate Open Discussions among Methodologists regarding Our Findings and Their Implications for Both Published IS Research and Future Practices.

• Herbal Formula Science
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• v.23 no.2
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• pp.225-233
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• 2015

Objectives : The purpose of this study was to investigate the interpretation of the Pyeongwi-san(PWS) prescription in order to obtain the evidence for clinical applications. Methods and Result : We interpreted on the PWS-related contents based on 15 classic books, analyzed it according to followed categories ; origin, indication and precaution, usage, meaning of name, physiological and pathological situation of PWS, explain about each herbs. Conclusion : 1. PWS was first mentioned in the Bakjebang, its application was enhancing appetite. Application of PWS not only expanded digestive disease, infectious disease, and pain in articular, but also used to toniyfing drug. 2. Generous application method of PWS was ‘Sujunbok(水煎服)’. Pill preparation(丸劑) and decoction with salt(鹽湯劑) were also used 3. "Pyeongwi(平胃)“ in PWS means "flatten the stomach". There are some theory about methodology to "Pyeongwi (平胃)“, one is "drain the pathogen in stomach(敦阜說)”, other is "tonifying stomach's healthy qi(卑監說)“, the other is compromise theory. 4. Most medical literature related application situation of PWS to dampness(濕邪) in stomach. In Gangsulwongobangsunju, there are more detailed explain focused on metal qi(金氣), and fire qi(火氣) 5. Atractylodes japonica Koidz(蒼朮) drys dampness and fortifys the spleen, Magnolia officinalis Rehder(厚朴) eliminates dampness and treats fullness, Citrus reticulata Blanco(陳皮) moves and drains qi, Glycyrrhiza uralensis Fisch(甘草) tonify and harmonize in herbal formula

• Journal of Oriental Neuropsychiatry
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• v.22 no.3
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• pp.87-100
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• 2011

Objectives : Neurosis, psychosomatic disease from which most of out-patients suffer originated marital problem in clinical setting, In Oriental medicine, concept and clinical cases of the couple therapy is insufficient. So we suggest the theoretical background and evidence of oriental medical approach. Methods : We searched the theoretical perspectives of recent couple therapy and suggested the psychotherapy with couples in oriental medicine and its clinical utilization. Results : 1. Advantages of the couple therapy in oriental medicine were easy to relationship and emotional communication. because oriental medicine were available to approach of symptom pattern about somatic symptom due to marital problem. 2. Oriental medical therapy, for example, acupuncture, moxibustion, cupping, herbal medicine, etc. connects doctors and the patients easily, unlike dialogue-centered western psychotherapy. 3. The Ii-Gyeung-Byun-Qi Therapy(移精變氣療法) resolve the marital suppressed feeling easily, Gi-Un-Go-Roen Therapy (至言高論療法) is useful in four principle-marital role, communication, sex life, theory of Hwa-Byung. 4. The principle of 'sorrow restraints anger(悲勝怒)' and 'pleasure restraints sorrow(喜勝悲)' in Oh-Ji-Sang-Seung Therapy(五志相勝療法) accords with forgiveness and recovery that is ultimate goal of the couple therapy. Conclusions : Except existing therapy for recovery of marital relation, We suggest the somatic symptom centered approach based on mind and body unification in oriental medicine. This principle would bring the benefit from the marital to familial relation. From now on, we should correct the theory, need the theorical systematization. Then we should develop the program for recovery of marital relation and examine the hypothesis.

• International Area Studies Review
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• v.14 no.3
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• pp.157-177
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• 2010

This study analyzes the effect of fiscal decentralization on economic growth by using each province city's panel data of China from 1985 to 2008. By using Recently developed fiscal decentralization index and autonomy of local government quantified this study finds the following conclusions. The increase of inflation rate affects positive effect on Chinese economy. This is the trade-off relationship with the growth of Chinese economy by the Phillips Curve theory. So this suggests the instability of Chinese economy. The affiliation of WTO of China shows positive effect on Chinese economy. This can be translated as the real evidence about free trade theory of Classical School. Expenditure decentralization in China led to economic growth and revenue decentralization also affected positively although it was not as much as expenditure decentralization's effect. Central tax and local tax negatively influenced economic growth; and differently from our expectation, local government autonomy quantified was not relevant to economic growth.

• Analyses & Alternatives
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• v.5 no.2
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• pp.39-76
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• 2021

This article examines the effect of CEO's political connections on firm performance in Chinese private firms. Following the upper echelon theory and human capital theory, CEO's personal characteristics affect the strategic decision-making of the firm, and it is also firm-specific advantages that work as the human capital for the sustainable growth of the firm. In this regard, this article tries to empirically confirm whether CEO's political connections have positive effects on firm performance as the firm's human capital by dividing the Chinese local governments, which is a direct subject of political connections hierarchically. In addition, this research examines the mediating effects of government subsidies between political connections and firm performance. To verify these questions, we use a sample of 9,849 observations of 1,451 private firms listed on the Shanghai and Shenzhen stock exchanges from 2008 to 2016, the results show that the CEO's political connections are positively related to firm performance. Moreover, we find that only political connections with the provincial local government had a positive effect on firm performance. It indicates that values and influences of human capital held by CEOs only affect when they are related to the highest local government. Finally, when CEOs have political connections with city-level, it shows complete mediating effect. It provides empirical evidence to find that CEO's political connections affect firm performance as the results of non-market strategic of firms.

• Geotechnical Engineering
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• v.1 no.1
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• pp.5-12
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• 1985

Ocassionally it is used for simple extensions of Terzahgi's theory to account for time-depend- tint loading but there is little evidence of application in more complicated consolidation theories that take into account such effects as nonlinear stress.strain, layered systems or large strains. The purpose of this paper provides an efficient computer algorthm based on numerical analysis using finite difference method which account for multi-layered soils to determine the degree of consolidation and excess pore pressures relative to time and positions more realistically. The explicitly scheme of solving the consolidation equations has been investigated from the point of view of the stability conditions and the convergence with variance of the operator as well as to obtain an optimal divided depth ratios of total depth. A comparison of the settlement predictions with both the classical analysis and the algorithm based on numerical analysis indicates that the new algorithm scheme is found to be superior to the classical theory in the layered soils.