• KSBB Journal
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• v.22 no.3
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• pp.123-128
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• 2007

One drawback of conventional kinetic resolution of racemic epoxides by epoxide hydrolase (EH) is that the theoretical yield can never exceed 50%. This 50% limitation can be overcome by using enantioconvergent process, in which both enantiomers of the racemic epoxide are transformed via stereochemically matching pathways into a single enantiopure diol as the sole product in 100% theoretical yield. In order to make a single enantiopure vicinal diol, the two enantiomers of the racemic epoxide must be hydrolyzed with retention and inversion of configuration each other. The EHs should be enantio- and regiospecific at the same time. The enantioconvergent hydrolysis with EHs and relevant biotransformation for preparing enantiopure epoxides and vicinal diols with a high yield are reviewed.

• Journal of Microbiology and Biotechnology
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• v.18 no.11
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• pp.1773-1784
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• 2008

Effects of various industrially important carbon sources (glucose, sucrose, xylose, gluconate, and glycerol) on shikimic acid (SA) biosynthesis in Escherichia coli were investigated to gain new insight into the metabolic capability for overproducing SA. At the outset, constraints-based flux analysis using the genome-scale in silico model of E. coli was conducted to quantify the theoretical maximum SA yield. The corresponding flux distributions fueled by different carbon sources under investigation were compared with respect to theoretical yield and energy utilization, thereby identifying the indispensable pathways for achieving optimal SA production on each carbon source. Subsequently, a shikimate-kinase-deficient E. coli mutant was developed by blocking the aromatic amino acid pathway, and the production of SA on various carbon sources was experimentally examined during 51 batch culture. As a result, the highest production rate, 1.92 mmol SA/h, was obtained when glucose was utilized as a carbon source, whereas the efficient SA production from glycerol was obtained with the highest yield, 0.21 mol SA formed per mol carbon atom of carbon source consumed. The current strain can be further improved to satisfy the theoretically achievable SA production that was predicted by in silico analysis.

• Journal of the Korean Geotechnical Society
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• v.20 no.3
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• pp.13-22
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• 2004

In case of the lateral movement accurring at soft ground where a row of piles are installed, the crown failure at external arch zone of soil arching is firstly developed, and the cap failure at wedge zone in front of piles is lastly developed. Therefore, the lateral earth pressure acting on a row of piles due to soil movement should be calculated in each condition of crown and cap failures around piles. A theoretical equation of crown failure can be proposed using a cylindrical cavity expansion theory. The theoretical equation of crown failure is mainly affected by two factors. One is related to soil properties such as internal friction angle, cohesion and horizontal pressure, and the other is related to pile factors such as diameter, installation interval. Meanwhile, the yield range of lateral earth pressure is established in the estimation of theoretical equation based on crown and cap failures around piles. The theoretical values based on crown and cap failures are compared with the experimental values. The experimental values are located in the range proposed by theoretical values. Thus, it is confirmed that the theoretical values proposed in the study are very reasonable.

• Transactions of the Korean Society of Automotive Engineers
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• v.6 no.2
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• pp.228-234
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• 1998

The buckling is one of the major two nonlinear problems. One is the material non-linearity and other is the geometrical nonlinear. Material non-linearity has occurred when the buckling stress of material exceeded the yield stress of material. The material non-linearity must be taken into account when the buckling analysis of thick plate is performed. In this study, inelastic modulus that is used to calculate the buckling strength is taken to account for the material non-linearity. The results from experiments are used to formulate the semi-theoretical formula. The analysis results generated by the use of semi-theoretical formula are close to the experimental data.

• Proceedings of the KSRS Conference
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• 1999.11a
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• pp.154-157
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• 1999

Microwave polarimetric backscattering from a wet soil surface had been measured using a Ku-band polarimetric scatterometer at the incidence angles ranging from 10$^{\circ}$ to 70$^{\circ}$ Since the accurate target parameters as well as the radar parameters are necessary for radar scattering modeling, a complete and accurate set of ground truth data were also collected, from which accurate measurements were made of the rms height, correlation length, and dielectric constant. The measured polarimetric backscattering coefficients (vv-, hh-, vh-, hv-polarizations) were compared with theoretical models and empirical models. A new semi-empirical model for microwave polarimetric radar backscattering from bare soil surfaces was developed using polarimetric radar measurements and the knowledge based on the theoretical and numerical solutions. The model was found to yield very good agreement with the backscattering measurements of this study.

• Journal of the Korean Chemical Society
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• v.4 no.1
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• pp.67-69
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• 1957

The synthetic method of tetramethyl-4,4'-diaminobenzophenone accomplished by W. Michler is to pass gaseous carbonyl chloride in dimethylaniline until theoretical value of weight increases at room temperature and synthesize the ketone by heating it at above 120$^{\circ}C. In the result of the experiment to synthesize the ketone by Michler's method, it was observed that if gaseous phosgen was to be used at room temperature according to the method, the gas inhaling tube would be closed up by reaction products (gruel-like crystals) before the theoretical amount of gases passed in and causing difficulty for gas to be produce or inhaled With a view to remove the difficulty, the author examined an article published by W. Michler entitled. "The synthesis of organic acid with phosgen" and guessing that the use of liquid phosgen could overcome the difficulty, succeeded in synthesizing the substance in good yield easily by reacting dimethylaniline with phosgen that was condensed into liquid state.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1988.10a
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• pp.18-23
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• 1988

This study on the elasto-plastic analysis of spherical shell by rigia element method is classified into two parts : (1) theoretical consideration on elasto-plastic analysis of spherical shell, (2) elastic and elasto-plastic analysis of spherical shell with the open stiff ring. In 1982, Y. Tsuboi proposed the new analytical method which is called the rigid element method, for analyzing the elasto-plastic behavior of wall-type precast concrete structures by applying the concepts of rigid bodies-sprins model (i．e., when structures reach their ultimate state of leading, they may be yield, collapsed ana crushed into pieces, and each part or piece of structures mar move like a rigid body.). In this paper, for improvement and expansion this rigid element method, it is proposed the adaptation equation of rectangular-shaped spherical element and rectangular-shaped spherical bending element developed by present authors, and the analytical procedure for the elastic and the elasto-plastic increment method of structures.

• Tunnel and Underground Space
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• v.1 no.2
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• pp.218-228
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• 1991

Natural stress measurements have been made at two sites at the depth of 280m from surface by means of stress relief overcoring methods using three directonal deformation gage. Attempts have been made to determine the state of natural stress in the rock and provide useful basic data to investigate the stress distribution and the determination of yield zone around powerhouse cavern. The magnitude and the direction of the miximum principal stress obstained from in-situ stress measurements is -96.1kgf/$\textrm{cm}^2$ and N38$^{\circ}$W, N35$^{\circ}$W respectively. Vertical stresses are in approximately agreement with the theoretical value. The ratio of measured to theoretical stresses are 85% at two sites. The ratio of average horizontal to vertical stresses(k=($\sigma$h)ave/$\sigma$v is 1.07.

• Journal of KSNVE
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• v.7 no.2
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• pp.331-345
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• 1997

A theoretical formulation for the analysis of free vibration of clamped-free cylindrical shells with plates attached at arbitrary axial position(s) was completed and it was programed to get the numerical results which yield natural frequencies and mode shape of the combined system of the plate and the shells. The frequencies and mode shapes from theoretical calculation were compared with those of commercial finite element code, ANSYS. In order to validate the theory, modal test was also performed by impact test and FFT analysis. The results shows good agreement with those of ANSYS and test results in frequencies and mode shapes. The method developed herein is likely to be used for the analysis of the free vibration of the clamped-free circular cylindrical shells with any kinds of lids such as hollow circular plates, conical shells, spherical shells, or semi-spherical shells.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2009.05a
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• pp.172-175
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• 2009

The purpose of this study is to predict the forming limit diagram (FLD) of strain-rate sensitive materials on the basis of the Marciniak and Kuczynski (M-K) theory. The strain-rate effect is taken into consideration in such a way that the stress-strain curves for various strain-rates are inputted into the formulation as point data, not as curve-fitted models such as power function. To solve the nonlinear system of equations derived from the equilibrium and constraints in the groove region and the safe zone, the Newton-Raphson method is used. The theoretical FLDs using four different yield criteria, that are von Mises, Hill (1948), Hill (1979), Logan and Hosford, are compared with the experimental, numerical (FEA) and other theoretical results. A new trial is made where a modified M-K model having n-step grooves is introduced to describe a real localized neck.