• 한국콘텐츠학회논문지
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• 제10권6호
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• pp.27-34
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• 2010

본 논문은 가중 퍼지소속함수 기반 신경망(neural network with weighted fuzzy membership functions, NEWFM)과 웨이블릿 기반의 특징 추출기법을 사용하여 왼쪽 또는 오른쪽의 운동 형상을 분류하는 방안을 제안하고 있다. 초기 특징을 추출하기 위해서 첫 번째 단계에서 웨이블릿 변환(wavelet transforms)을 이용하여 뇌파(electroencephalogram, EEG) 신호로부터 웨이블릿 계수들을 추출하였다. 두 번째 단계에서는 첫 번째 단계에서 추출한 웨이블릿 계수들을 통계적인 방법인 주파수 분포와 주파수 변동량을 이용하여 60개의 초기 특징을 추출하였다. 이들 60개의 초기 특징은 NEWFM에서 제공하는 비중복면적 분산 측정법에 의해 중요도가 가장 낮은 특징을 하나씩 제거되면서 정확도가 가장 높은 6개의 최소 특징을 선택되었다. 이들 6개의 최소 특징을 NEWFM의 입력으로 사용하여 86.43%의 정확도를 구하였다.

• 감성과학
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• 제16권4호
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• pp.527-534
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• 2013

본 연구에서는 코히어런스 분석을 통하여 시각집중 기간 동안 시간 변화에 대한 뇌기능과 관련된 공간-주파수간 연관관계를 해석하였다. 집중관련 시각자극 실험 데이터를 통해 ${\theta}$와 ${\alpha}$ 대역에서 서로 다른 두피 위치간 위상연관변화를 확인하였다. 좌우 전두엽, 전두엽과 두정엽 간 뇌유발전위는 P100, N200지점에서 위상동조를 보였으며, 전두엽과 후두엽 간 뇌유발전위는 시각 처리 정보가 반영되는 P300지점에서 위상동조를 보였다. 고정된 길이의 창을 이용하는 단구간 푸리에 변환에 비하여 연속 웨이블릿 변환은 모 웨이블릿의 파라미터 조정을 통한 다중해상도 분석이 가능하였다. 따라서 연속 웨이블릿 변환을 이용한 코히어런스 결과가 시간변화에 대한 뇌유발전위의 공간-주파수간 연관관계의 변화를 확인하는데 유효함을 확인하였다. 비 집중 자극수행에 대해서는 위상동조 현상이 나타나지 않았다.

• Pediatric Infection and Vaccine
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• 제5권2호
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• pp.289-295
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• 1998

Group B Streptococcal sepsis and/or meningitis is one of the most serious and common diseases in the neonatal period with high mortality and frequent complications. We have experienced a case of late onset type group B streptococcal sepsis and meningitis with a complication of subclavian vein catheterization catheterization. This 29-day-old male neonate was admitted to intensive care unit with the presentation of fever and septic shock. He was born with Cesarean delivery at 36 weeks and 3 days of gestational age. He showed multiple episodes of seizure after admission and group B streptococcus was isolated from blood. CSF profiles 10 days after admission showed the features of bacterial meningitis without organism isolated. Diffuse cerebral infarction was detected on brain CT 24 days after admission. In the 13th hospital day, the complication of subclavian vein catheterization occurred; Guide wire was cut during insertion and the distal portion of it(2.5cm) was retained in the left subclavian vein. We removed the retained guide wire with goose-neck snare catheter via right femoral vein. This case was presented with a brief review of the literatures.

• The Journal of Korean Physical Therapy
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• 제19권3호
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• pp.1-9
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• 2007

Purpose: Previous studies have suggested that BDNF has a role in plasticity and survival following spinal cord injury and treadmill exercise increases BDNF levels in the normal brain and spinal cord. We attempted to determine whether swimming exercise improve motor function following experimental contusive spinal cord injury and whether motor outcome is associated with BDNF expression. Methods: Thirty six Sprague-Dawley rats (weight, 250 to 300 g) were divided into control (n=18) and experimental swimming group (n=18). Spinal cord injury was produced using NYU-spinal impactor at the eleven thoracic levels in both groups. Swimming exercise started $7^{th}$ day from SCI operation, lasted 5 min per day, 5 days a week for 4 weeks and then exercise times a day were increased in one number to each week. Motor functional recovery was determined by the Basso-Beattie-Bresnahan (BBB) locomotor rating scale, modified inclined board plane test, histological findings, H&E and BDNF expression observed at $1^{th}$, $3^{rd}$, $7^{th}$, $14^{th}$, $21^{st}$ and $28^{th}$day after injury. Results: 1. The BBB scores were higher in experimental group than control group at $14^{th}$, $21^{st}$ day (left hind limb) and at $21^{th}$ day (right hind limb) (p<0.05) after injury. 2. The inclined board plane test were significantly greater in experimental group than control group at $7^{th}$ day (p<0.05), $14^{th}$ and $28^{th}$ day (p<0.01) after injury. 3. The BDNF expression was severe revealed in experimental group than control group at $7^{th}$, $14^{th}$ and $28^{th}$ day after injury. Conclusion: This study suggests that swimming applied from the early phase after spinal cord injury be beneficial effects in motor functional recovery.

• 한국융합학회논문지
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• 제8권9호
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• pp.211-216
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• 2017

중증외상 환자 CT(Computed Tomography)검사 시 검사 보조자의 방사선 피폭경감을 위하여 새로운 융합적 모델의 망토 차폐체를 제작하여 그 유용성을 평가하고자 한다. 실험 방법으로 뇌혈관 CT 검사와 동일한 조건에서 두부 팬텀과 인체 팬텀을 이용하여 기존 차폐체와 새롭게 개발된 망토 차폐체를 이용하여 심장, 양쪽 액와부 그리고 갑상샘 부위를 유리선량계로 피폭선량을 측정하였다. 새롭게 개발된 차폐체가 기존의 차폐체 보다 방사선 차폐율이 심장 61.9 %, 좌측액와부 46.2 %, 우측액와부 69.8 %, 그리고 갑상샘 71.1 % 로 각각 높게 측정되었다. 새롭게 개발된 망토 차폐체가 방사선 피폭을 감소시키는데 매우 유용하며 향후 새롭게 개발된 융합적 모델의 망토 차폐차가 방사선 피폭을 감소시키는데 있어 큰 기여를 할 것으로 판단된다.

• 한국융합학회논문지
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• 제10권5호
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• pp.103-110
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• 2019

알츠하이머형 치매(Alzheimer's disease, AD)가 입체시 지각에 영향을 미치는지를 규명하고자 정상노인, AD환자, 경도인지장애(mild cognitive impairment, MCI)환자 각각 20명을 대상으로 입체시 지각능력을 검사했다. 화면 좌우에 두 개의 정육면체가 제시되었으며, 참가자들은 둘 중 자신에게 더 가까운 물체를 지적하였다. 이 때 물체들 간의 상대적 거리를 절대부등과 상대부등으로 분리하여 조작하였으며, 각 부등 유형에서 교차부등과 비교차부등으로 부등의 방향도 함께 변화시켰다. 그 결과 MCI환자들과 AD환자들이 정상노인 못지않게 정확하게 수행한 것으로 나타났다. 이런 결과는 입체시 지각과정이 AD의 영향을 거의 받지 않는 증거로 볼 수 있다. 이런 결과를 AD로 인해 영향을 받는 고차원 시각 과정과 비교하면서 논의하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7277-7281
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• 2013

Background: Globally, there have been important changes in trends amongst gender, histology and smoking patterns of lung cancer cases. Materials and Methods: This retrospective study was conducted on 466 patients with lung cancer who were registered in Regional Cancer Center, Regional Institute of Medical Sciences, Manipur from January 2008 to December 2012. Results: Most were more than 60 years of age (67.8%) with a male: female ratio of 1.09:1. Some 78.8% of patients were chronic smokers with male smoker to female smoker ratio of 1.43:1. Consumption of alcohol was found in 29.4%, both smoking and alcohol in 27.5%, betel nut chewing in 37.9% and tobacco chewing in 25.3%. A history of tuberculosis was present in 16.3% of patients. The most frequent symptom was coughing (36.6%) and most common radiological presentation was a mass lesion (70%). Most of the patients had primary lung cancer in the right lung (60.3%). The most common histological subtype was squamous cell carcinoma (49.1%), also in the 40-60 year age group (45.9%), more than 60 year age group (51.6%), males (58.1%) and females (41.8%). As many as 91.9% of squamous cell carcinoma patients had a history of smoking. About 32.5% of patients had distant metastasis at presentation with brain (23.8%) and positive malignant cells in pleural effusions (23.1%) as common sites. The majority of patients were in stage III (34.4%), stage IV (32.5%) and stage II (30.2%). Conclusions: Our analysis suggests that the gender gap has been narrowed such that about half of the patients diagnosed with lung cancer are women in this part of India. This alarming rise in female incidence is mainly attributed to an increased smoking pattern. Squamous cell carcinoma still remains the commonest histological subtype. Most of the patients were elderly aged and presented at locally or distantly advanced stages.

• Journal of Chest Surgery
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• 제25권11호
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• pp.1362-1368
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• 1992

Between March 1986 and November 1992, thirty-one patients with left main coronary artery stenosis[LMCAS, over 50% of cross sectional area] were revascularized at Seoul National University Hospital. The incidence of LMCAS was 20.8%[31/149]. The male:female ratio was 15:16. Age ranged from 39 to 70 years, with a mean age of 51 years. The anginal syndrome was composed of 23 unstable, 6 stable and 2 post-infarction angina preoperatively. There were sixteen isolated LMCAS, four ostial stenosis and eleven combined distal and /or right coronary artery stenosis. The degree of LMCAS was 50-74% in 21 patients[67.7%], 75-89% in one[3.6%] and 90-99% in 9[29.1%]. There was no case with 100% obstruction. Of the total patients with LMCAS, 11 patients received 4 distal anastomoses, another 11 patients had 3 distal anastomoses, and 8 patients needed 2 distal anastomoses. The overall operative mortality was 12.9%[4 /31], and the incidence of which was higher than the remaing group [6.8%, 8/118]. The causes of death were myocardial infarction[2 patients], ventricular arrhythmia[1 patient] and brain damage[1 patient]. All patients have been followed-up for average 28.9 months[1-76 months]. There was no late death. But one patients experinced anginal recurrence. In conclusion, making allowance for its notorious clinical results and relatively higher incidence in Korea, aggressive surgical techniques such as retrograce myocardial perfusion may be mandatory while we are in a learning phase.

• 한국안전학회지
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• 제24권3호
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• pp.71-78
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• 2009

During a learning process, a human being is assumed to experience knowledge-based behaviors, rule-based behaviors, and skill-based behaviors sequentially if Rasmussen was right. If any psycho-physiological symptom to those different levels can be obtained, it can be useful as a measure whether a human being is fully trained and has gotten a skill in his work. Therefore, this study aimed to draw relationships between human performance measures and psycho-physiological measures while committing a computer-simulated pointing task by utilizing the power spectrum technique of EEG data, especially with the ratio of relative beta-to-alpha band power. The result showed that, during correct responses, the ratio came to stabilize as all the performance data went stable. However, response time was not a simple linear function of task difficulty level only, but a joint function of task characteristics as well as behavior levels. Comparing relative band power ratios from errors and correct responses, activated states of one's brain could be explained, and characteristics of the task could understood. To tell that of pointing task, correlations around C3, C4, P3, P4 and 01, 02 area were significant and high in correct response cases whereas most correlation coefficients went down in error cases standing for imbalance of psycho-motor functions. Though task difficulty was the only one factor that could influence on relative band power ratio with statistical significance, it should be comprehended to mean a different way of expression indicating task characteristics since at least error-some situation could be explained with the help of relative band power ratio that absolute band power failed.

• Tuberculosis and Respiratory Diseases
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• 제54권6호
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• pp.645-650
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• 2003

저자들은 우측 흉부 불편감을 주소로 내원한 25세 여자 환자를 개흉 조직 검사를 시행하여 원발성 횡격막 기원 악성 섬유성 조직구종을 진단하였고 ifosfamide, doxorubicin으로 항암 화학 요법 시행 후 부분 관해가 있었으나 진단 후 12개월째 외래 추적 검사 중 뇌전이로 사망한 젊은 여성 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.