Journal of the Korea Convergence Society (한국융합학회논문지)

Korea Convergence Society (한국융합학회)
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A Convergent Approach to Gain a Better Understanding of Alzheimer's Disease: Stereoscopic Vision

융복합적 접근을 통한 알츠하이머형 치매의 이해 증진 : 양안 지각

  • Kim, Nam-Gyoon (Department of Psychology, Keimyung University) ;
  • Lee, Ho-Won (Department of Neurology, School of Medicine, Kyungpook National University)
  • 김남균 (계명대학교 심리학과) ;
  • 이호원 (경북대학교 의과전문대학원 신경과)
  • Received : 2019.04.02
  • Accepted : 2019.05.20
  • Published : 2019.05.28
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Abstract

The present study investigated the effects of AD on stereoscopic vision. Sixty participants (20 AD patients, 20 mild cognitive impairment patients, 20 healthy elderly controls) participated in the study. Two cubes, one on the left and the other on the right of the center of the monitor, appeared at varying distances from the observer with their relative distances controlled in two disparity conditions (absolute vs relative disparity) combined with two disparity directions (crossed vs uncrossed disparity). Participants identified the object that appeared closer to them. Results demonstrated comparable performance with all three groups performing accurately, suggesting that the effect of AD on stereopsis is negligible. Discussion focused on brain pathology affected by AD involving high level visual processing.

알츠하이머형 치매(Alzheimer's disease, AD)가 입체시 지각에 영향을 미치는지를 규명하고자 정상노인, AD환자, 경도인지장애(mild cognitive impairment, MCI)환자 각각 20명을 대상으로 입체시 지각능력을 검사했다. 화면 좌우에 두 개의 정육면체가 제시되었으며, 참가자들은 둘 중 자신에게 더 가까운 물체를 지적하였다. 이 때 물체들 간의 상대적 거리를 절대부등과 상대부등으로 분리하여 조작하였으며, 각 부등 유형에서 교차부등과 비교차부등으로 부등의 방향도 함께 변화시켰다. 그 결과 MCI환자들과 AD환자들이 정상노인 못지않게 정확하게 수행한 것으로 나타났다. 이런 결과는 입체시 지각과정이 AD의 영향을 거의 받지 않는 증거로 볼 수 있다. 이런 결과를 AD로 인해 영향을 받는 고차원 시각 과정과 비교하면서 논의하였다.

Keywords

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Fig. 1. A stereogram used in the present study. Two cubes are rendered in cross-disparity such that, when viewed with a pair of anaglyph glasses, both appear floating in front of the monitor. The cube on the right is smaller than that on the left but appears closer to the observer.

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Fig. 2. Percent correct (with standard error bars) plotted against distance for each condition of disparity direction in the absolute disparity condition (top panel) and in the relative disparity condition (bottom panel). Here, d1 and d4 correspond, respectively, to the smallest and largest distance pairs.

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Fig. 3. Mean percent correct plotted against distance for each condition of disparity direction.

Table 1. Clinical and demographic data of the participants (Standard Deviation)

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