• Title/Summary/Keyword: the key quantity method

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Liposome Immunoassay for Bioactive Substances (리포좀을 이용한 생리활성물질의 면역학적 분석법)

  • Kim, Chong-Kook;Park, Kyung-Mi
    • Journal of Pharmaceutical Investigation
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    • v.24 no.4
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    • pp.201-215
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    • 1994
  • Recent development in the immunochemical technique has resulted in a new ultrasensitive analytical method known as liposome immunoassay (LIA). Liposome is a key element in performing liposome immunoassays, specifically designed to participate in immune reactions. A variety of markers can be encapsulated in liposomes and used as quantitative indicators of reactions. Liposome immunoassay based on agglutination, complement-mediated Iysis, cytolysin-mediated Iysis, detergent-mediated Iysis or destabilization of the liposomal membrane have been reviewed. The quantity of markers released from liposomes should be proportional to the concentration of the analytes. Therefore, liposomal agglutination and Iysis which are essential to liposomal Iysis are critically reviewed to provide a better understanding of liposome immunoassay. Based on the literature review of recent advances in liposome immunoassay for bioactive substances, this assay method may provide a convenient, specific and highly sensitive method for detecting and measuring trace amount of clinically relevant substances in the future.

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A Study on developing WBS based QDBS(Quantity Database System) for the schedule and the cost data integration for road construction project (도로공사의 공정 및 공사비 연계활용을 위한 디지털 수량산출정보시스템(QDBS) 개발 연구)

  • Yun, Seok-Heon;Kim, Seong-Sig
    • Korean Journal of Construction Engineering and Management
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    • v.8 no.4
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    • pp.119-127
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    • 2007
  • Cost and Schedule is the most important information, and how efficiently manage this information is the key issue for Construction Project Management. Domestically, systematic scheduling method such as CPM network is not only used widely but integration of time and cost information also is. In order to effectively integrate and use the time and cost information, it is suggested that WBS(Work Breakdown Structure) based QDB(Quantity Database) should be generated from the design phase and, WBS and QDB related system tool should be supported. It could be helpful to relate and integrate other construction project information.

A Study on the Quantatitive Evaluation of Voltage Stability Improvement Effect By the T/L-Loss System Identification Method (송전손실 상태식별법을 이용한 전압안정성 개선효과의 정량적 평가에 관한 연구)

  • Choi, Jong-Key;Lee, Bong-Yong;Kim, Jung-Hoon
    • Proceedings of the KIEE Conference
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    • 1994.11a
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    • pp.45-47
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    • 1994
  • The simulation of reactive power compensation in 5-bus and 25-bus system was conducted using transmission-line loss system identification method. Sensitivities of maximum load-power with respect to reactive power compensation was identified by the simulation. With sufficient reactive power compensation at the first voltage-collapsing load-bus, the first voltage collapse could be prevented until the next voltage-collapsing load-bus lost its voltage stability. And the total compensated reactive power at the first voltage-collapsing bus means reactive power margin of voltage collapse or distance to voltage collapse. This quantity can be useful for determining the size of compensating devices or the site to compensate.

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Development of a Method for Reliability Evaluation of Transmission System under the Deregulated Electricity Market (규제완화된 전력시장 하에서의 송전계통 신뢰도 평가방법의 개발)

  • Cha, Jun-Min;Kim, Hong-Sik;Choi, Jae-Seok;Oh, Kwang-Hae
    • Proceedings of the KIEE Conference
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    • 2000.07a
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    • pp.397-399
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    • 2000
  • This paper presents a method for assessing reliability indices of transmission system. Because successful operation of electric power under the deregulated electricity market depends on transmission system reliability management, quantity evaluation of transmission system reliability is very important. The key point idea is based on that the reliability level of transmission system is equal to reliability level difference of between composite power system(HLII) and generation system(HLI). It is sure that risk indices of reliability of composite power system are larger than those of generation system. It is the reason that composite power system includes uncertainties and capacity limit of transmission lines. The characteristics and effectiveness of this methodology are illustrated by the case study using MRBTS.

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An Experimental Study on the Bond Split Mechanism of High Strength Concrete (고강도 콘크리트의 부착할렬기구에 관한 실험적 연구)

  • 장일영
    • Journal of the Korea Concrete Institute
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    • v.11 no.4
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    • pp.129-136
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    • 1999
  • For the prediction of concrete-steel bond ability in reinforced concrete, many countries establish specifications for the pullout test. But these methods hardly to consider many parameters such as strength, shape, diameter and location of steel, concrete restrict condition by loading plate, strength of concrete and cover depth etc, and it is difficult to solve concentration and disturbance of stress. The purpose of this study is to propose a New Ring Test method which can be rational quantity evaluations of bond splitting mechanism. For this purpose, pullout test was carried out to assess the effect of several variables on bond splitting properties between reinforcing bar and concrete. Key variables are concrete compressive strength, concrete cover, bar diameter and rib spacing. Failure mode was examined and maximum bond stress-slip relationships were presented to show the effect of above variables. As the result, it appropriately expressed general characteristics of bond splitting mechanism, and it proved capability for standard test method.

A Study on Predicting Presidential Election Results by Analyzing Twitter Message Contents: A Focus on the 18th Presidential Election in Korea (트위터 메시지 분석을 통한 선거 결과 예측 고찰: 18대 대선을 중심으로)

  • Lee, SeoYoung;Kwon, SangJib
    • The Journal of the Korea Contents Association
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    • v.19 no.4
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    • pp.174-186
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    • 2019
  • Twitter is very popluar with users who desire social interaction as it is a highly effective method of communicating compared to traditional communication platforms; and thus has garnered considerable interest from the academic community. This research reveals how election results can be predicted by the factors of total volume of messages, positive messages and negative messages tweeted about a candidate. Social matrix analysis revealed that the quantity of twitter messages was a strong predictor of election results in the 18th presidential election in Korea. In addition, more positive messages than negative messages about a candidate from twitter users recorded better results in the election. This research found that the total quantity of messages, positive messages, and negative messages as key factors for predicting election result. Future studies should investigate other SNS platforms to discover what is the most effective communication strategy on each platform.

Decision-Making based on Uncertain Information in a Beer Distribution Game U sing the Taguchi Method (맥주매송게임에서 다구찌 방법에 의한 불확실 정보 기반 의사결정 연구)

  • Lee, Ki-Kwang
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.33 no.3
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    • pp.162-168
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    • 2010
  • Information is known to be a key element for the successful operation of a supply chain, which is required of the efficient ordering strategies and accurate predictions of demands. This study proposes a method to effectively utilize the meteorological forecast information in order to make decisions about ordering and prediction of demands by using the Taguchi experimental design. It is supposed that each echelon in a supply chain determines the order quantity with the prediction of precipitation in the next day based on probability forecast information. The precipitation event is predicted when the probability of the precipitation exceeds a chosen threshold. Accordingly, the choice of the threshold affect the performances of a supply chain. The Taguchi method is adopted to deduce a set of thresholds for echelons which is least sensitive to changes in environmental conditions, such as variability of demand distributions and production periods. A simulation of the beer distribution game was conducted to show that the set of thresholds found by the Taguchi method can reduce the cumulative chain cost, which consists of inventory and backlog costs.

An analytical approach of behavior change for concrete dam by panel data model

  • Gu, Hao;Yang, Meng;Gu, Chongshi;Cao, Wenhan;Huang, Xiaofei;Su, Huaizhi
    • Steel and Composite Structures
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    • v.36 no.5
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    • pp.521-531
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    • 2020
  • The behavior variation of concrete dam is investigated, based on a new method for analyzing the data model of concrete dam in service process for the limitation of wavelet transform for solving concrete dam service process model. The study takes into account the time and position of behavior change during the process of concrete dam service. There is no dependence on the effect quantity for overcoming the shortcomings of the traditional identification method. The panel data model is firstly proposed for analyzing the behavior change of composite concrete dam. The change-point theory is used to identify whether the behavior of concrete dams changes during service. The phase space reconstruction technique is used to reconstruct the phase plane of the trend effect component. The time dimension method is used to solve the construction of multi-transformation model of composite panel data. An existing 76.3-m-high dam is used to investigate some key issues on the behavior change. Emphasis is placed on conversion time and location for three time periods consistent with the practical analysis report for evaluating the validity of the analysis method of the behavior variation of concrete dams presented in this paper.

Folic acid supplementation regulates key immunity-associated genes and pathways during the periparturient period in dairy cows

  • Khan, Muhammad Zahoor;Zhang, Zhichao;Liu, Lei;Wang, Di;Mi, Siyuan;Liu, Xueqin;Liu, Gang;Guo, Gang;Li, Xizhi;Wang, Yachun;Yu, Ying
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.9
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    • pp.1507-1519
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    • 2020
  • Objective: The current research was aimed to profile the transcriptomic picture of the peripheral blood lymphocytes (PBLs) associated with immunity in Chinese Holsteins supplemented orally with coated folic acid during the periparturient period. Methods: The total of 123 perinatal cows were selected for this study and divided into three groups; group A (n = 41, 240 mg/500 kg cow/d), group B (n = 40, 120 mg/500 kg cow/d) and group C (n = 42, 0 mg/cow/d) based on the quantity of folic acid fed. Three samples of PBLs were selected from each folic acid treated group (high, low, and control) and RNA sequencing method was carried out for transcriptomic analysis. Results: The analysis revealed that a higher number of genes and pathways were regulated in response to high and low folic acid supplementation compared to the controls. We reported the novel pathways tumor necrosis factor (TNF) signaling, antigen processing and presentation, Staphylococcus aureus infection and nuclear factor (NF)-kappa B signaling pathways) and the key genes (e.g. C-X-C motif chemokine ligand 10, TNF receptor superfamily member 1A, cluster difference 4, major histocompatibility complex, class II, DQ beta, NF-kappa-B inhibitor alpha, and TNF superfamily 13) having great importance in immunity and anti-inflammation in the periparturient cows in response to coated folic acid treatment. Conclusion: Collectively, our study profiled first-time transcriptomic analysis of bovine lymphocytes and compared the involved cytokines, genes, and pathways between high vs control and low vs control. Our data suggest that the low folic acid supplementation (120 mg/500 kg) could be a good choice to boost appropriate immunity and anti-inflammation as well as might being applied to the health improvement of perinatal dairy cows.

A Study on Demand Forecasting Model of Domestic Rare Metal Using VECM model (VECM모형을 이용한 국내 희유금속의 수요예측모형)

  • Kim, Hong-Min;Chung, Byung-Hee
    • Journal of Korean Society for Quality Management
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    • v.36 no.4
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    • pp.93-101
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    • 2008
  • The rare metals, used for semiconductors, PDP-LCS and other specialized metal areas necessarily, has been playing a key role for the Korean economic development. Rare metals are influenced by exogenous variables, such as production quantity, price and supplied areas. Nowadays the supply base of rare metals is threatened by the sudden increase in price. For the stable supply of rare metals, a rational demand outlook is needed. In this study, focusing on the domestic demand for chromium, the uncertainty and probability materializing from demand and price is analyzed, further, a demand forecast model, which takes into account various exogenous variables, is suggested, differing from the previously static model. Also, through the OOS(out-of-sampling) method, comparing to the preexistence ARIMA model, ARMAX model, multiple regression analysis model and ECM(Error Correction Mode) model, we will verify the superiority of suggested model in this study.