• Clinical and Experimental Pediatrics
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• 제56권12호
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• pp.505-513
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• 2013

Because the prevalence of allergic diseases has significantly increased in recent years, understanding the causes and mechanisms of these disorders is of high importance, and intense investigations are ongoing. Current knowledge pinpoints immune tolerance mechanisms as indispensable for healthy immune response to allergens in daily life. It is evident that development and maintenance of allergen-specific T cell tolerance is of vital importance for a healthy immune response to allergens. Such tolerance can be gained spontaneously by dose-dependent exposures to allergens in nature or by allergen-specific immunotherapy. Allergen-specific immunotherapy induces regulatory T cells with the capacity to secrete interleukin-10 and transforming growth factor-${\beta}$, limits activation of effector cells of allergic inflammation (such as mast cells and basophils), and switches antibody isotype from IgE to the noninflammatory type IgG4. Although allergen-specific immunotherapy is the only method of tolerance induction in allergic individuals, several factors, such as long duration of treatment, compliance problems, and life-threatening side effects, have limited widespread applicability of this immunomodulatory treatment. To overcome these limitations, current research focuses on the introduction of allergens in more efficient and safer ways. Defining the endotypes and phenotypes of allergic diseases might provide the ability to select ideal patients, and novel biomarkers might ensure new custom-tailored therapy modalities.

• Journal of the East Asian Society of Dietary Life
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• 제7권2호
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• pp.153-158
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• 1997

This study was designed to find out the effects of soybean protein and milk protein between nondiabetic and diabetic rats. The experimental results are summarized as follows. 1. Total food intake was higher in diabetic soybean protein group than other groups but it was not significant. 2. The change of body weight was lower in diabetic soybean protein group than other groups and the soybean protein was effective to maintain the ideal body weight. 3. The effects of lowering total cholesterol and glucose in serum was higher in soybean protein groups than the milk protein groups.

• Journal of Marine Bioscience and Biotechnology
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• 제12권1호
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• pp.50-58
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• 2020

Sphacelaria is a filamentous brown algal genus that can be epibiotic on macroalgae, marine plants, and sea turtles. Its important role in benthic ecosystems, exposure to different stressors (e.g., grazing), and use as a model organism make Sphacelaria ideal for assessing physiological responses of organisms to environmental inputs. Single-cell RNA sequencing is a powerful new probe for understanding environmental responses of organisms at the molecular (transcriptome) level, capable of delineating gene regulation in different cell types. In the case of plants, this technique requires protoplasts ("naked" plant cells). The existing protoplast isolation protocols for Sphacelaria use non-commercial enzymes and are low-yielding. This study is the first to report the production of protoplasts from Sphacelaria fusca (Hudson) S.F. Gray, using a combination of commercial enzymes, chelation, and osmolarity treatment. A simple combination of commercial enzymes (cellulase Onozuka RS, alginate lyase, and driselase) with chelation pretreatment and an increased osmolarity (2512 mOsm/L H₂O) gave a protoplast yield of 15.08 ± 5.31 × 10⁴ protoplasts/g fresh weight, with all the Sphacelaria cell types represented. Driselase had no crucial effect on the protoplast isolation. However, the increased osmolarity had a highly significant and positive effect on the protoplast isolation, and chelation pretreatment was essential for optimal protoplast yield. The protocol represents a significant step forward for studies on Sphacelaria by efficiently generating protoplasts suitable for cellular studies, including single-cell RNA sequencing and expression profiling.

• Journal of Hospice and Palliative Care
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• 제2권2호
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• pp.138-143
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• 1999

Accurately estimating survival times in terminal cancer patients is very difficult for palliative care clinicians. But a reasonably accurate estimate of survival would permit the medical team to : Plan the ideal therapeutic strategy between overtreatment and too early discontinuation of specific therapy. Answer any questions asked by the patient or family. Organize adequate assistance for the patient concerned. Decide on the eligibility of the patient for clinical trials and whether to begin a treatment, the effects of which will not be immediate. This case was a 79 year-old male patient with colon cancer. He complained of dry mouth, anorexia, weight loss and showed KPS $40{\sim}50$ on admission day. 40 days later he died. To improve patient/family quality of life, it is necessary to improve the ability to estimate accurately a patient's length of survival.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• 제37권3호
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• pp.22-36
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• 2019

This research identified landscape characteristics of Chilitan(칠리탄) area, which had been managed by Son Giyang(1559~1617, p. Ohhan), in order to understand the political viewpoint and ideal landscapes, sought after by Confucian scholars in the 16~17th century. As the research method for the interpretation of each scene's spatial strucutres and meanings, paintings and poems in Chiltanjungsipyukgyeongdo(the Paintings of the 16 Scenes of Chiltanjung Area) were analyzed, which were followed by the on-site survey. Son lived hermit life with the nature after he decided to retire into the country for the chaotic political environment in the 4^th year of Gwanghaegun's reign. Admiring Eum Jareung(B.C. 39-41, p. Eumgwang)'s hermit life, he named a headstream to Chilitan, erected pavilion and made place for angling by the stream, as Eum did in the hermitage. However he worried the king and royal politics in spite of his hermit life, which showed his political viewpoint of Confucianism. In addition, every column of buildings in the garden was named in order to imply both thoughts of Neo-Confucianism and Idleness Naturalism, which highlight a moral training and being comfortable amid poverty and taking pleasure in and honest life style. The present landscape of wonlim could be back to 1936, where Unganru, Byeokripjae and Chiltanjung are surrounding Eupcheondang. Chines character, such as Jimamsuseok, Giam, Ohhansonsunseongjanggujiso and Jogi, are inscribed on the rocks in the landscape garden, from which placeness could be inferred. According to the record of the construction, pine, fir, paulownia, ginkgo, peach trees, bamboo and lotus were planted, and ginkgo, bamboo, crape myrtle, pine and chestnut tress are still living in the garden, which mean plants had been planted in the light of their practical values as well as symbolic meanings. The method for describing 16 scenes of Chiltanjung could be characterized to the structure of 「Place+Scene(a particural activity, event, or action), and these placeness could be analyzed by categorizing the scene to near, middle and far views. Each scene symbolically presents a hermit, noble man, Taoist ideology, homeland, or peacetime, which were adpoted to depict landscapes of Chiltanjung area as the Confucian utopia.

• Journal of the East Asian Society of Dietary Life
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• 제12권4호
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• pp.299-306
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• 2002

This study was undertaken to compare the obesity related dietary factors among rural middle school students living in the Daegu.Kyungbuk area. Anthropometric data showed that mean height and weight were 162.7$\pm$8.6cm and 53.9$\pm$9.8kg in 220 male students and 158.4$\pm$6.2cm and 51.0$\pm$7.6kg in 210 female student. Mean BMIs for boys and girls were 19.00$\pm$2.35 and 19.30$\pm$2.45, respectively. 71.36% of male students and 71.9% of female students were underweight by the BMI index. Students who skipped the breakfast were up to 66.8%. The reasons for skipping a meal for both sexes were significantly different. Compared to males, more female respondents felt guilty and depressed related to eating. Furthermore, females were more significantly concerned about body image, diet and body weight (p<0.001), and they were not satisfied with their weight. The sources of information on obesity and diet were radio and TV in males, while females gathered information from magazines and friends. The ideal body weight of male students was heavier than the actual body weight while female students desired a thinner body shape. In conclusion, a different approach for nutrition education based on sex should be developed, and implemented fur adolescents.

• Journal of agriculture & life science
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• 제44권3호
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• pp.7-14
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• 2010

Alternative subirrigation way, capillary wick system (CWS) was tested to reduce labor cost, waste water, contamination of ground water, and use of fungicide compared to overhead irrigation system (OIS). CWS helped reduce remarkably the working hours for watering from 4 hours in OSI to just 5 minutes. Labor cost was saved 98% in CWS compared to OIS. By the physical characteristics of various growing media, 1 coconut coir+2 perlite (v/v) mixture was selected because it had an ideal distribution of three phase, e.g. 1 solid: 1 liquid: 2 gas phase. Medium mixture containing scoria had so high bulk and particle density to hurt root. In bark-containing medium, the liquid phase and the percent saturation of liquid phase with time elapsed was lower than that of other mixture. It meant that the mixture contained very low level of water. Application of CWS for cyclamen pot production played an important role in reducing the incident of fusarium wilt symptom from 18% in conventional over watering system to 4%. Cyclamen pot irrigated by capillary wick had shorter petiole and more leaves than those by overhead watering. As a result, this system was highly beneficial to get uniform pot products with high quality. It improved water and nutrient solution efficiency relative to conventional overhead irrigation system (OIS).

• Journal of Korean Academy of Nursing
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• 제26권1호
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• pp.107-126
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• 1996

The Purpose of this study was to build a substantive theory about the experience of postpartum depression. The qualitative research method used was rounded theory. The interviewees were eight others who had experienced postpartum depression. The data were collected through in-depth interviews with audiotape recording done by the investigator over a period of twelve months. he data were analyzed simultaneously by a constant comparative method in which new data were continuously coded into categories and properties according to Strauss and Corbin's methodology. Analysis the grounded data resulted in 28 concepts being identified. Eight categories emerged from the analysis. The categories were regret, loss of freedom, isolation of oneself, heartache, loss, emotional upset, avoidance, recovery. These substantive categories are consistent with precious research results. Causal conditions included : regret, loss of freedom. Phenomena : heartache, loss, emotional upset. Context : isolation oneself. Intervention condition : avoidance. Action/interaction strategies : desire for recovery. Consequences : recovery. These categories were synthesized into the core concept-The process of filling the empty loss of self. The process of the experienced postpartum depression was ① change after delivery, ② searching for a reason for depression, ③ effort to recover from postpartum depression, ④ recovery from postpartum depression and return to previous life. The process of recovery from postpartum depression was proceeded by ① support from others, especially husband, ② resolution of stressful life events, ③ reconstructing of life goals and resolution strategies, ④ acceptance of depression and seeking psychiatric treatment. Seven hypotheses were derived from the analysis. ① Mothers who experienced stressful life event and economic problem are more depressive. ② Mothers who have conflict with parents are more depressive. ③ The more somatic symptoms, the more depression. ④ Social support facilitates recovery from postpartum depression. ⑤ Mothers who have lower self-esteem are more depressive. ⑥ Mother's role overload disturbs recovery from postpartum depression. ⑦ Ideal maternal identity facilitates recovery from postpartum depression. Through this substantive theory, nurses can understand the importance of postpartum depression management.

• Journal of Biosystems Engineering
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• 제29권6호
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• pp.521-530
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• 2004

The solar powered water pump is very ideal equipment because solar power is more intensive when the water is more needed in summer and it is very helpful in the rural area, in which electrical power is not available. The average solar radiation power is $3.488\;kWh/(m^2{\cdot}day)$ in Korea. In this study, the experimental system of the water pump driven by the radiation energy were designed, assembled, tested and analyzed fur realizing the solar powered water pump. Energy conversion ken radiation energy to mechanical energy by using n-pentane as operating material was done and the water pumping cycles were able to be continued. The quantity of the water pumped per cycle ranged from 2 L to 10 L depending on the level of the valve open area far the vapour supply. The average quantity was about 4,366 cc. The thermal efficiency was about $0.018\%$. The pressure level of the n-pentane vapour in flash tank was about $110\~150\;kPa$ and that in the water tank was $93\~130\;kPa$. The pressure in the condenser during cycles was maintained as about 70 kPa. The condensation of the n-pentane vapour in the water tank was increased with the cycles even though the internal and external insulation were done. Air tank performance was better with increasing of the water piston displacement and the water could be pumped with the water piston displacement becoming higher than 6,500 cc.

• Journal of Family Resource Management and Policy Review
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• 제8권2호
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• pp.61-84
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• 2004

This thesis attempted to generate ideal tea culture space that connects environment and culture. Therefore, this examines: First, history of tea and the characteristics of tea culture space from Gochosun to modern times was reviewed Second, psychological factors (spirit of tea) of Korea tea culture space were reviewed. Third, the connection between the concept of tea culture space and Human Ecosystem Model by was analyzed. Also, this thesis examined how the culture of ecosystem and why tea culture space is needed. because tea includes varieties of ingredients for protecting environmental pollution. Finally, tea culture spaces were reviewed each region during Chosun dynasty, and tea culture space of recent tea users. In order to study tea culture space, complex residential area and single residential areas were compared. The useful of tea culture space as a ecological space was also examined. To achieve the purpose of this study, related literatures were reviewed, and investigations of museums and a survey on modern living space were also conducted. The results show that the space of our tea culture were affected by nature worshipping of Gochosun, Buddhism of Koryo, and Confusianism of Chosun with 'Pungryu', the idea that enjoys nature, thereby applying environment-friendly ecological beauty to their living space and life. The cultyral space in Korea is composed of natural environment such as mountain, sea, rock, or trees and artificial environment such as pond or pavilion. In the future, oriental culture with metaphysical value will lead the world culture, and especially, tea culture would play an important role regardless of nationality, race, religion, and ideology. Therefore, establishing a tea culture space in a living space would be the fundamental methods that would be able to settle down such tea life into our daily life. Our attempts to create ecological tea culture space as a integrated cultural space of natural, artificial, and human behavioral environment will contribute to enhance our quality of life.