• The Korea Journal of Herbology
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• v.27 no.4
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• pp.33-44
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• 2012

Objectives : There is a pressing need to determine the clinical and scientific validity of herbal therapies for animal model with atopic dermatitis since some differences in systemic cytokine polarization between in animal model and in patients with atopic dermatitis has been reported. New studies for tang, medicinal herb itself or effective ingradients of medicinal herb showing anti-atopic dermatitis effectiveness are reviewed in terms of cytokine regulation. Methods : Those herbal therapies used to treat atopic dermatitis in animal model were introduced and the expression pattern of cytokine and the activity of mast cell were compared in both animal model and patients with atopic dermatitis. Results : In case of atopic dermatitis in human, there is a biphasic pattern of cytokine expression in atopic dermatitis, with acute skin inflammation associated with a predominance of IL-4 and IL-13 expression from Th2 cells, and chronic inflammation associated with increased IL-5 from Th2-cells and IFN-${\gamma}$ from Th1-cells. However, a pattern of cytokine expression in animal model with atopic dermatitis is not matched well to the biphasic pattern of cytokine expression in patients with atopic dermatitis. In addition, a kind of cytokine is different by animal model with atopic dermatitis. These differences would make herbal medicines, showing their effectiveness on atopic dermatitis, difficult to apply to patients with atopic dermatitis. Conclusion : The pattern of local cytokine expression plays an important role in modulating tissue inflammation, and in atopic dermatitis this pattern depends on the acuity or duration of the skin lesion. Thus, in order to develop medicinal herb itself or effective ingradients of medicinal herb showing anti-atopic dermatitis effectiveness, biphasic pattern of cytokine expression should be considered in animal model with atopic dermatitis.

• The International Journal of Costume Culture
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• v.4 no.2
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• pp.115-123
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• 2001

The crossover in fashion refers to the coordination of different items, each with a different atmosphere. In a broad sense, it is the mutual exchange across the existing areas, that is, the creation of a new style by disparate and opposite elements coexisting in a look. This paper studies typical features of the crossover shown in modern fashion based on sub-culture by examining the concept and formation factors of the crossover through social aspects rather than particular art modes to predict the current fashion and suggest a new direction. Crossover fashion appeared in social and cultural environments, has four characteristics : the visual discordance of sexes, the appearance of the lingerie look, the mixture of folk style, and the appearance of the reactionary mode. The crossover, appeared in sub-cultures and diffused into the public, may be considered the creation of a new sense of beauty and a possibility for the future. It is expected to keep expanding ifs range in fashion, since it is an expression of human will to restore liberal sensibility not confined to formality.

• Journal of Fashion Business
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• v.4 no.1
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• pp.113-123
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• 2000

The purpose of this study is firstly to have the grasp of the tendency of animality represented in modern fashion. The second purpose is to analyze the form modeling of animality represented in modern fashion and the third one is to examine into an aesthetic character of animality represented in modern fashion. The method we adopt for this study is to analyze the designers' work which shows the fashion animality. The result of this study is follows. The tendency of animality represented in modern fashion presented in a printed form which patterned the animals' cuticle, a shape of animals, a symbolic image, and a future suggestive expression. The form modeling of animality is a reality and the aesthetic character is the vigorous beauty and the gorgeousness of original colors. So, animality represented in modern fashion is to offer the various ideas as well as to lead the curiosity about the fashion in the future and the coexistence into the fashion.

• Journal of the Korean housing association
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• v.5 no.2
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• pp.77-86
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• 1994

The attempts in pursuit of humanity in contemporary architecture brought about meaning to the 'Locality as a main conception which opens new potentiality at this confused period. Contemporary housing design should meet the indigenous ‘Locality’ of the building sites environment. An adequate adaptation to the ‘Locality’ will bring more efficient use, lower running-costs, and longer durability of original beauty of the houses. Our contemporary houses should admit general requirements at this time and they should be expressed through not only space but also form and design. Finally, we must find the direction of elevation planning of Korean contemporary houses, inquiring into design elements of ‘Locality’ in the view point of transformation and analyzing how the elements are represented in contemporary houses. This research was aimed to find how to optimize an elevation design of houses in adapting to the Korean indigenous ‘Locality’ in order to create a domestic housing design suitable for Korean life style, however, one cannot ignored elements of the Korean traditional mode of living.

• Journal of the Korea Furniture Society
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• v.12 no.1
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• pp.69-79
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• 2001

The purpose of this study is to examine the characteristics of Arne Jacobsen's chair design. He was one of the few creators who inscribed his name in both the history of architecture and furniture design. His works reflected a form of "Regional Modernism" in which traditional techniques collide with functionalist beliefs. This grafting of ideas generated a person aesthetics which he used to establish a suitability of scale, detail an program for each design. In the material aspect, he had enjoyed using the plasticity of the plywood, polyurethane, tubular steel and in the formative aspect, organic form is combined with minimalization of material and simplicity. To sum up what is unique about Arne Jacobsen's chair design, it is that it is distinguished by a clear understanding and expression of beauty from nature, a complete understanding of the material used and the melding of traditional and functional techniques to generate organic form.anic form.

• Journal of Korea Society of Digital Industry and Information Management
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• v.8 no.2
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• pp.105-116
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• 2012

Minimalism combines the adjective 'minimal' and the suffix 'ism', and was first coined in the 1960s. Minimalism draws on the belief that when the use of artistic skills and adaptation is minimized and only the essentials or core is expressed, the discrepancy or distance between reality and art can be kept to a minimum; and thus, true reality can be achieved. To realize minimalism, artists creating paintings, sculptures and other forms of visual art eliminate unnecessary elements and strip objects to its essentials. And hence, most minimalist artwork used minimum amount of color and focused on expressing the geometric essence of objects. Such simplistic styles of minimalism can be seen today in various designs. Apple's iPod design and other product designs as well as graphic designs are just few of the examples. Drawing on the spirit of minimalism, Icongraphics pursues beauty and pleasure in the minimal use of color and form. And what lies beneath Icongraphics' artistic style is its pursuit of simplistic essentials, sending a strong message to the digitalized and complex lives of modern people.

• International journal of advanced smart convergence
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• v.10 no.4
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• pp.225-232
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• 2021

Obesity is caused by the accumulation of triglycerides in adipocytes by the differentiation and lipid synthesis process of pre-adipocytes, and excessive accumulation of adipocytes by the activated Adipogenesis process within the differentiated cells. Therefore, inhibiting the differentiation of adipocyte cells or controlling the adipogenesis process is known as an effective treatment method for obesity. This study evaluates the inhibition of Red beet root extract on pancreatic lipase and pre-adipocyte cell differentiation. Also it evaluates the Red beet root extract activities on C/EBP-𝛼,𝛽, and PPAR-𝛄. The experiments proved that the Red beet root extract inhibits pancreatic lipase by concentration dependency. Further, in 3T3-L1 inhabitation experiment, it was found Red beet root extract inhibited adipocyte formation. Red beet root extract also inhibits the expression of C/EBP-𝛼, C/EBP-𝛽, and PPAR-𝛾 which effect the process of adipocytic differentiation. We therefore concluded that RBE has a high potential to further studies on anti-obesity effect.

• Journal of the Korea Furniture Society
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• v.21 no.4
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• pp.293-303
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• 2010

With changing systems of wealth creation around the 21st century, crafts(traditional and industrial crafts) are affected by the trend of changes or lead the trend, that is to say, a turning point of paradigm has come. Values of crafts give the value of users, and the tradition and modern coexists in the trend of times changing from the tradition to the modern so crafts artists’ works are diversified and used in design industries. Based on a place of expression showing various beauty of crafts, identity of design is established through ‘Craft Consilience’ of intangible cultural assets, master craftsman, crafts artists, crafts industries, and crafts departments. As master craftsman and furniture designers meet together to mix master craftsman’s idea with designers’ idea, the new Korean crafts furniture is suggested.

• Journal of the Korean Applied Science and Technology
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• v.34 no.4
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• pp.769-777
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• 2017

To research the effects of marigold extract, which is used mixed with calendula extract, on collagen growth and MMP-1 expression in human fibroblast, we measured cytotoxicity, collagen growth and MMP-1 expression by using HDF cells. The result of measurement showed over 80% cell survival rate in $5{\sim}100{\mu}g/mL$ concentration of marigold extract and calendula extract for HDF cells, which indicates there is no cytotoxicity. The result of measuring collagen synthetic abilities showed both types of extract had collagen synthetic ability increase dose dependently, by 25% in $100{\mu}g/mL$ concentration of marigold extract, and by 7% in $100{\mu}g/mL$ concentration of calendula extract. The result of experimenting the effect on MMP-1 expression showed that both types of extract suppress MMP-1 expression. The result of observing phosphorylation of p-JNK and p-ERK, which are known to be involved with MMP-1 expression, revealed that marigold extract effectively suppresses MMP-1 expression through signaling pathway of p-JNK and p-ERK. The above results confirm the wrinkle improvement effect of marigold extract, and furthermore, it can be used as a cosmetic ingredient for anti-aging.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2003.05a
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• pp.160-165
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• 2003

Art of today is expressed in various images incorporated in industrial development and visible in industrial parks, modern cities. Avant garde art and modernism brought abstract and conceptual art into conflict in the early 20th century and they absorbed elements of each other and grew into post modernism, which emerged in the 1960s and is still current. The avant garde challenged what was lofty and sometimes opposed modernism and sometimes fed it in cycles until post modernism was established. 'Trans avant garde', which, unlike modernism asserted individual expression, also appeared in the 1970s. Trans avant garde is spiritual art in which the artist's conversation with his soul returns. This study examines the readjustments the trans avant garde is making in its relationship with the dominant ethos of different values and offers the world art with important spiritual beauty. Trans avant garde art takes many forms, from thing to huge, which are manifested every where in architecture, interior design and everyday life.