• 복식문화연구
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• 제19권5호
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• pp.957-969
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• 2011

This study intended to analyze the grunge look as a mode of expression and as a characteristic of the fashion of the 21st century, arguing that the look expressed not only an outward appearance or sub-culture but also a change in our attitude and spirit about contemporary fashion. In the study, I carried out an empirical analysis focused on the collection from 2001S/S to 2010F/W and a literature review. In my results, I classified the grunge look into the following categories: 1. mix and match layering; 2. patchwork, collages, and assemblage using all objects as well as clothing materials; and 3. distressing techniques, such as bleaching and dyeing, unweaving, and tears and holes. I also classified the characteristics of grunge into the following categories: 1. conspicuous destitution, which is intentionally expressed by skillful techniques and craftsmanship, indicating that modern people want to attract attention and be distinguished from others, which reflects an attitude of superiority through ironic fashion choices; 2. high lighting the dissolution of decoration, where destruction, poverty and recombination shown in the grunge look emerged as an artificial and intentional ugly aesthetic in contrast to the existing elegant and sophisticated image; and 3. satire and playfulness, as grunge expresses alienation and conflict in modern society through satire and sarcasm, not attacking or avoiding, but through playful and sarcastic engagement so as to decrease poverty and give temporary freedom.

• 한국의류산업학회지
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• 제9권6호
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• pp.663-670
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• 2007

Arts is the expression of reasoning and conscious life of human and arouse human the concept of existence, utmost emotion and excellent thoughts. Also it makes humans life very abundant. I make it come first to get rid of the art thirst on the opposite sight of technical one for hair as on part of humans body. Next purpose is that to confirm the esthetic value of 'hair arts' by solidify the academic ground of beauty arts through creating 'hair arts' works and learning and make the direction for the beauty industry and education of the next generation. In this study I investigated the Greek myth and the hair styles of ancient Greek Goddesses. On the basis of that symbols I elaborated hair formative works made of metal and studied, analyzed and displayed that. Work No.1 'aphne' pictures the second of changing into a laurel tree avoiding the love. Secondly 'Muse Erato' was exhibited the peaceful figure that have enough the fine melodies. 'Leda' brings out the feature of Leda resembling a swan and the fourth piece, 'Eos' conveys the brilliant and mystery of dawn. So this study conducted based on the concept of practical hair and have made efforts to be close to theoretical manufacturing research needed at making hair arts works and academic one needed at organic design composition for pioneering new field, 'art hair.' I hope these 'hair arts' works make creativity of the practise hair alive. It will be very thankful to me if this study can help even though slightly for splendid beauty arts to make its status firm as a one part of arts, and there are following studies.

• Biomolecules & Therapeutics
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• 제24권5호
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• pp.552-558
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• 2016

Severe complications associated with EV71 infections are a common cause of neonatal death. Lack of effective therapeutic agents for these infections underlines the importance of research for the development of new antiviral compounds. In the present study, the anti-EV71 activity of norwogonin, oroxylin A, and mosloflavone from Scutellaria baicalensis Georgi was evaluated using a cytopathic effect (CPE) reduction method, which demonstrated that all three compounds possessed strong anti-EV71 activity and decreased the formation of visible CPEs. Norwogonin, oroxylin A, and mosloflavone also inhibited virus replication during the initial stage of virus infection, and they inhibited viral VP2 protein expression, thereby inhibiting viral capsid protein synthesis. However, ribavirin has a relatively weaker efficacy compared to the other drugs. Therefore, these findings provide important information that will aid in the utilization of norwogonin, oroxylin A, and mosloflavone for EV71 treatment.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2009년도 춘계 종합학술대회 논문집
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• pp.229-234
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• 2009

현대사회는 산업의 다양화로 디자인 영역은 다각화로 확장되어 가고 있으며 여러 학문들과 통합과 통섭 등 을 통하여 여러 가지 새로운 기능성을 제시하고 있다. 사람들의 사고방식, 감성의 변화, 그리고 행동양식에도 큰 변화가 일어나 새로운 표현방식과 미적 가치를 추구하다. 그러함 속에서 전통에 대한 새로운 인식 혹은 새로운 소재로서 수묵화 표현이 늘어나고 있다. 본 고 에서는 수묵이 나타나게 된 역사적, 사회적 배경을 기초하여 그 표현방식과 분석을 중심으로 고찰하였고 동양적 전통미와 정서적 감성에 부합되는 미적 가치로서 수묵화적 표현을 제시하였다. TV-CM디자인에 나타난 수묵표현의 활용에 대해 연구하는 것으로 수묵의 개념, 특징, 분류, 표현방식을 분석하고 새로운 수묵기법 혹은 동양적 표현을 통하여 디자인 영역을 확대하고자 한다.

• 디지털융복합연구
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• 제16권1호
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• pp.337-342
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• 2018

금속공예 분야에서 점차 쇠퇴되는 대공작품의 예술적 미적 가치를 연구하기 위해 시작된 본 연구는 디자인 요소인 점, 선, 면, 형을 중심으로 한 조형 표현방법으로 선과 면을 선정하고 이를 금속조형으로 시각화 하였다. 선행연구를 통해 알아본 선과 면의 미적 해석은 생명력 있는 반복적 아름다움으로 정의 되었는데 연구자는 여기에서 더 나아가 반복적이면서도 변화를 느낄 수 있는 조형 작품을 나타내고자 했다. 그 결과 선과 면이 규칙적 반복이 아닌 자연스럽게 점진되는 변화를 통해 어려운 기법이나 고도 기술의 제작 방법 없이도 선과 면의 단순한 변화 속에서 느껴지는 미적 아름다움을 표현할 수 있는 탐구의 대상이 가능함을 알 수 있었다. 또한 쇠퇴해가는 금속조형의 고부가가치 산업으로서의 성장을 예측할 수 있었다. 본 연구를 시작으로 향후 선과 면의 활용이 조형요소로서 매우 다양한 미적표현 방법으로 응용될 수 있는 연구가 계속 되기를 바란다.

• 한방안이비인후피부과학회지
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• 제34권4호
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• pp.12-23
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• 2021

Objectives : This study is to investigate the anti-aging and antioxidant effects of Naesohwangryeon-tang(NSHRT) extract in Hs68 fibroblasts. Methods : The fibroblast cell line Hs68 cells were used and MTT analysis was performed to measure the cell viability of Naesohwangryeon-tang, and then MMP-1 was induced with the cytokine TNF-𝛼 to confirm the anti-aging effect through real-time PCR and ELISA. In addition, ROS was induced with the TNF-𝛼 to confirm the anti-oxidant effect through DCF-DA. The signaling pathway according to the antioxidant effect was performed by western blot. Results : Naesohwangryeon-tang did not show cytotoxicity at all concentrations(100-800㎍/㎖) treated on Hs68 cells, and the inhibitory effect of MMP-1 was also confirmed. In addition, it was confirmed that the intracellular ROS increased by TNF-α was decreased by Naesohwangryeon-tang, and it was confirmed that the expression of NQO1 was increased in a concentration-dependent manner of Naesohwangryeon-tang. Conclusions : These results suggest that Naesohwangryeon-tang can be used as an anti-aging material by demonstrating the anti-aging and antioxidant effects of Naesohwangryeon-tang.

• Toxicological Research
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• 제33권2호
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• pp.125-134
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• 2017

The effects that ultraviolet rays elicit on collagen synthesis and degradation are the most common causes of wrinkle formation and photo-aging in skin. The objectives of this study were to evaluate the effects of Angelica acutiloba root ethanol extract (AAEE) to promote collagen synthesis and inhibit collagen degradation in human dermal fibroblasts. By examining total polyphenol and flavonoid contents, electron donating ability, radical scavenging activity, and superoxide dismutase-like activity, we found that AAEE exhibited fairly good antioxidant activity. Treatment with AAEE significantly increased type I procollagen production by cultured fibroblasts, as well as reduced ultraviolet-induced matrix metalloproteinase-1 (MMP-1) expression and MMP-2 activity in a dose-dependent manner (p < 0.05). In addition, AAEE significantly increased TIMP-1 mRNA expression (p < 0.05), although without an associated dose-dependent increase in TIMP-1 protein expression. In summary, we suggest that AAEE may be a potentially effective agent for the prevention or alleviation of skin-wrinkle formation induced by ultraviolet rays.

• 한국패션뷰티학회지
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• 제3권2호
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• pp.31-38
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• 2005

Make-up changes facial images. In particular, eyebrow make-up is a part of changing expression most easily and effectively. While color make-up is helpful to produce women's desired image with their favorite colors, eyebrow make-up is hidden actor to give a clear impression to others. Therefore, this study connected facial type which is an important factor deciding facial image with eyebrow, examined image of eyebrow make-up and that changed by facial types and aimed to be helpful in producing more effective facial image with eyebrow make-up considering one's facial type. Consequently, it was found that eyebrow make-up was a great factor in making better facial impression and image and complementing the weakness of facial type. h strong impression of facial type can be changed into soft shape or foolish shape in worse case depending on the types of eyebrow make-up. Eyebrow make-up shows charming image as angle of eyebrow is steep, heavy image as eyebrow is horizontal, cold image as eyebrow tail rises and simple and dull image as it lowers. Therefore, it is known that image of eyebrow make-up can be governed by several factors including angle and direction of eyebrow. Consequently, it is thought that most effective eyebrow make-up considers individual facial types, images of their eyes, noses and mouths and factors deciding angle, direction and colors of eyebrow.

• 한국융합학회논문지
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• 제9권9호
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• pp.299-307
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• 2018

본 연구에서는 천경자 그림에 표현된 색채를 응용하여 추상적 네일디자인을 작품제작으로 표현하고자 한다. 이를 통해 네일 디자인의 창의적인 아이디어 발상에 대한 기본 토대를 마련하고 네일디자인의 표현영역을 확대하는데 목적을 가진다. 실증적 연구로서 천경자의 미술적 특징이 잘 표현된 작품 5가지를 선정하여 NCS 자연색체계를 활용하여 색채 데이터 분석을 하였으며, 색채 활용과 더불어 네일디자인을 표현하기 위해 천경자의 작품 속 대표되는 5가지의 모티프를 선정하여 각 작품에 표현하였다. 본 연구의 작품 제작에 나타난 디자인은 네일디자인과 현대 한국회화의 융 복합이며, 이를 통하여 뷰티디자인의 예술성을 다양한 시각으로 재창조하여 네일 디자인을 개발하였다.

• Journal of Applied Biological Chemistry
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• 제65권2호
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• pp.93-99
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• 2022

Lysosome organelle extract (LOE) was derived from egg whites. The lysosome is an intracellular organelle that contains several hydrolysis enzymes. Previous studies have reported that LOE performs important functions, such as melanin de-colorization and anti-melanin production in B16F10 melanoma cells. However, its principal molecular and cellular mechanisms have not been elucidated till date. In non-cytotoxic conditions, LOE significantly inhibited α-MSH induced melanin synthesis of murine B16F10 cells. The anti-melanogenic activity of LOE was mediated by suppressing the mRNA expression of tyrosinase enzyme, tyrosinase related protein-1/2 (TRP-1/2), and microphthalmia-associated transcription factor (MITF) genes. By performing western blot analysis, we found that LOE significantly attenuated melanogenesis. In this case, LOE helped in increasing extracellular receptor kinase (ERK) phosphorylation in α-MSH induced B16F10 cells. Furthermore, MITF is found to be a key regulatory transcription factor in melanin synthesis; it was down-regulated by LOE through ERK phosphorylation. In this experiment, PD98059 (MEK inhibitor) was used to check whether LOE directly regulated the activity of ERK. Although LOE exerted inhibitory effect on melanin synthesis, we could not observe this effect in PD98059-treated α-MSH induced B16F10. These results strongly indicate that LOE is related to ERK activation and MITF degradation in anti-skin pigmentation. Hence, LOE should be utilized as a whitening agent of skin in the near future.