• Journal of Nutrition and Health
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• v.40 no.7
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• pp.593-600
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• 2007

Recent studies described the ${\varepsilon}4$ allele of apoE confers a two-to fourfold increased risk for late-onset Alzheimer#s disease (LOAD), but LOAD pathology does not all fit neatly around apo E. Therefore, the goal of this study was to find the association between Alzheimer and apo E4 genotype in the 107 elderly between 50 to 64 years old who visited to FHWC of Sungshin Women#s University. We conducted the questionnaire survey (general & 24 hr dietary recall), anthropometerics (BP, waist & BMI) and blood biochemistry (FBS & lipid profiles). LDL-c and HOMA-IR were calculated by Friedwald#s and Matthew#s formulas. The apo E genotyping was performed by PCR-RFLP method and subjects were divided into three allele groups (${\varepsilon}3$; wild, ${\varepsilon}2$ & ${\varepsilon}4;$ mutants). The apo E allele frequencies were 7.0% for the ${\varepsilon}2$, 83.6% for the ${\varepsilon}3$ and 9.3% for the ${\varepsilon}4$. In comparison with biochemistry characteristics by apo E genotype, FBS was significantly higher in ${\varepsilon}4(129.2{\pm}6.8)$ than that in the others (${\varepsilon}2$: $117{\pm}7.4$, ${\varepsilon}3$: $107.3{\pm}2.2)$ (p<0.01). More than forty percents of ${\varepsilon}4$ group shown the dyslipidemia [high TG (>150mg/dl) & low HDL (<40 mg/dl:male or <50 mg/dl: female)]. The cytokines levels such as IL-1 ${\beta}$, IL-6 and $TNF-{\alpha}$ were not different among three apoE alleles. After the adjusting sex, age & dietary fiber, LDL-c level was siginificantly higher in ${\varepsilon}4$ ($108.3{\pm}7.7$) than that in ${\varepsilon}2$ ($100.4{\pm}8.4$) (p<0.05). According to food intake and the recipe on the basis of 24 hr dietary recall, the elder]y with ${\varepsilon}4$ allele took higher intake frequency of the light -colored vegetable (radish, onion & cabbage) and pan-fried foods (sauteed beef and vegetables, stir-fried vienna with vegetables) than the others. We knew that the elderly with ${\varepsilon}4$ allele had been restricted the calories intakes with high dietary fiber (33.6+2.5 g/d) to maintain the normal level of FBS and LDL-c. On next study, the prevalence of Alzheimer#s disease in this population who has ${\varepsilon}4$ allele on the condition of calories restriction will be continually follow-up.

• Research in Community and Public Health Nursing
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• v.12 no.1
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• pp.32-38
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• 2001

This study focused on the understanding the life of the elderly in the institution by phenomenological method. The participants were seven. who were 4 men and 3 women living in the elderly institution in Taegu. The data were collected through the indepth interviews and participant observation from June 20. 1999 to January 10. 2000 and analyzed by phenomenological analytic method by Giorgi. The structure of the meaning were as follows: Unhappy life: irresponsibility. self-centered thought. hardness. Irresistible life: misfortune. unhealthiness. Reading their son's intention. Bitter life: unfair treatment from their sons and daughters, betrayed feeling for their being thrown away. Outside oriented life: a fear of others' attention, wrong information about institutionalized life, maladjustment. Self-consolation life: comfortableness, convenience, economic merit of low cost. Dissatisfied life: discomfort from communal living. unkindness of the institution staffs, depreciated tendency to the elder people, irrational social security system. economic distress, physical pain, restrained feeling. Tenacity to their sons and daughters longingness for their sons and daughters, regretableness, waiting, Regretable life: remorse for their past life. agony, guilty, loneliness, grief, self-abandonment, self-depreciation, other residents' death in common. Inharmonious life with other residents complaint, conflict, ignorance, selfishness. Yearning life for opposite sex: sexual interest. Preparing for their life: control over their body and mind, consideration for others. A life with hope: blessing death, forever healthfulness, affiliation to their family. From the results of this study an education and consultation should be done as soon as possible to remove the negative recognition of the institutional life to the facility residents. the family and the future consumers of elderly institution. To minimize the maladjustment to facility life of residents, a new program and interventions for the new comer's are needed. The thesis with above results will widen the understandings of institutional residents and an important guidance for a better nursing care in elderly institutions of korea.

• Journal of Animal Science and Technology
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• v.53 no.3
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• pp.195-202
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• 2011

Maintenance of adequate telomere length in developing cells is the most important concern to preserve the integrity of the genome. The length of telomere is strictly regulated by numerous telomere-binding proteins and/or interacting factors. Even though the expression of telomerase in the male reproductive tract has been characterized, developmental expressional profiling of telomerase and other telomere-associated proteins has not been determined in detail. The present study was attempted to examine expression patterns of catalytic subunit (Tert) and RNA component (Terc) of telomerase and two telomerase associated factors, telomerase associated protein 1 (Tep1) and TERF1 (TRF1) interacting nuclear factor 2 (Tinf2) in the testis and seminal vesicle of male rat during postnatal development. The real-time PCR analysis was utilized to quantify mRNA expression of molecules. The abundance of Tep1 mRNA in the testis and seminal vesicle was the highest at 5 months of age. Expressional fluctuation of Tinf2 during postnatal development was found in the testis, while expression of Tinf2 in the seminal vesicle was gradually increased until 5 months of age and then significantly decreased later. mRNA level of Tert gene in the testis was significantly increased at the adult and the elder, while the highest expression of Tert gene in the seminal vesicle was found at 5 months of age. Expression of Terc transcript in the testis and seminal vesicle was the highest at 5 months of age, followed by significant reduction at 1 and 2 years of ages. Such differential gene expression of telomere-associated factors and telomerase components in different male reproductive tissues during postnatal development indicates that maintenance of telomere length would be regulated in tissue- and/or age-specific manners.

• Research in Community and Public Health Nursing
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• v.15 no.2
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• pp.289-297
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• 2004

Purpose: This study was conducted to determine factors affecting workers' physiological somatic complain using the Job Stress Model proposed by the National Institute for Occupational Safety and Health (NIOSH). Method: Data were collected from the 1st to the 30th of December 1999. The subjects were 2.123 workers employed at 155 work sites. Collected date were analyzed through SAS/PC program. Result: According to individual characteristics, younger and women groups showed significantly higher physiological somatic complaint than elder men groups. By work condition, groups with higher physiological somatic complaint included workers of irregular shift work. Dark lighting, improper temperature in winter, improper ventilation, inappropriate humidity, unpleasant work environment and crowded work place were significantly related with physiological somatic complaint. By work-related factor, physiological somatic complaint was high in those with higher variance in work load, quantitative work load, role conflict, job burden, role ambiguity and future ambiguity. On the other hand, physiological somatic complaint was low in those with little underutilization of ability. As for the relationships between physiological somatic complaint and non-work related factors, physiological somatic complaint was high in workers who had a side job, were bringing up infants alone, cleaned the house alone, cared for the elderly and disabled persons, were studying, were volunteering at another organization, and were spending 5-10 hours in religious activities per week. Physiological somatic complain was in significantly negative correlations with overall social support, supervisory support and family support, but in significantly positive correlations with co-worker support. Conclusion: The main predictors of physiological somatic complain were gender, shift work pattern, overtime work, ventilation, role ambiguity, role conflict, future ambiguity, job control, variance in work load, overall social support, worker with side job, worker who cleans the house alone, worker who is studying. These predictors explained 19.10% of the total variance of physiological somatic complain.

• The Journal of the Korea Contents Association
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• v.15 no.9
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• pp.195-209
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• 2015

The purpose of this study is to conduct a meta-analysis of the research studies between the year 2000 and 2013 on the gender difference of the subjective-welling of Korean older adults. 74 research studies that meet the criteria are analyzed with SPSS and Meta-analysis macros. Results indicated that Korean elder men are better off in terms of subjective well-being (es = .1157, CI95% .0528-.1787) than women. No moderating effects are found. Few studies examined the interaction between the gender difference effect and main factors such as health and social relationship that affect subjective well-being. Based on the results some implications for future research are discussed.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.2D
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• pp.225-231
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• 2006

On-line shopping allows consumers to order goods via internet and receive them at homes or workplaces. Emergence of online shopping industry has brought the changes in the structure of freight industry, in the location selection pattern of industrial clusters and in the consumer's travel pattern. This trend is likely to continue, especially in Korea, as the society sees increases in women's participation in workforce, in population of the elder and in production pattern of manufacturing individually customized goods. Despite on-line shopping's heavy influence on travel demand, no study on this particular topic has been done yet, and thus the effect of on-line shopping on travel demand has not been properly reflected on policy making process. This paper suggests the transportation strategy to cope with this change based on the analysis of the effect of on-line shopping on personal travel demand.

• Journal of Korean Medical Science
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• v.33 no.52
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• pp.339.1-339.11
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• 2018

Background: Hip pain is a common musculoskeletal complaint in general practice. Although comprehensive diagnostic approach on hip pain is mandatory for adequate treatment, un- or mis-diagnosis is not rare in primary care. The aim of this study was to analyze descriptively un- or mis-diagnosed hip pain cases referred from primary care to a tertiary hospital, especially in young adults ${\leq}50years\;old$. Methods: We retrospectively analyzed a consecutive cohort of 150 patients (${\leq}50years\;old$) with chronic hip pain (${\geq}6weeks$), which was not diagnosed or misdiagnosed based on the information provided on the referral form. Results: Overall an average 32 cases/month were referred due to hip pain without a diagnosis or with an incorrect diagnosis. Among them, 150 patients were enrolled in this study and 146 (97.3%) could be allocated to a specific disease by using data from routine clinical practice. Four common final diagnoses were femoroacetabular impingement (FAI) syndrome (55.3%), hip dysplasia (HD, 13.3%), referred pain from the lumbar spine (9.3%), and spondyloarthritis (SpA, 7.3%). In patients with FAI syndrome, 37 (44.0%) had pincer-type FAI and 33 (39.8%) had combined-type. Although the pain site or gender was not tightly clustered, the distribution of final diagnosis was significantly different according to hip pain location or gender. Especially, SpA or HD was not observed in younger women subgroup or elder men subgroup, respectively, when stratified by the mean age of participants. Conclusion: Most (> 80%) young patients with hip pain, a difficult issue to diagnosis for many primary physicians, had FAI syndrome, HD, spine lesions, and SpA. This study could give a chance to feedback information about cases with un- or mis-diagnosed hip pain, and it suggests that primary physicians need to be familiar with the diagnostic approach for these 4 diseases.

• Journal of Korean Society of Transportation
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• v.18 no.4
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• pp.19-30
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• 2000

The purpose of the Paper is to estimate values of transfer related variables on route choices of subway users in Seoul. Four attributes were estimated affecting route choices, i.e. in-vehicle time, transfer time, number of transfers and existence of escalators. Stated preference and revealed preference techniques were used to estimate these values. The values of transfer related variables can be shown by in-vehicle time equivalents. One minute of transfer is 1.5∼2 times one minute of in vehicle times one time of transfer is 10∼15 times, and the existence of escalator is 2∼8 times. Women generally show stronger impedance than men and the elder does than the younger. Working, commuting and educational trips show stronger impedance than others too.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2006.11a
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• pp.123-130
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• 2006

This is a basic study to investigate possibility to application of cohousing model into Korea. Purpose of this study is to grasp respondents' housing value, and its influence on intention to live in cohousing. Research method used for this study was a social survey. Respondents were 214 married people residing in Seoul and its outskirts by accidential sampling. The collected data were analyzed by SPSS 12.0 program using frequency, mean, average, factor analysis, t-test, one-way ANOVA, Duncan's multiple range test, multiple regression and logit analysis. Result of this study was as follows. Housing values were classified into three categories named as individualism oriented housing value, tradition oriented housing value, and economy oriented housing value. Housing values were different by respondents groups. For example, individualism oriented housing value showed difference according to age and housing area. Tradition oriented housing value showed difference according to sex, occupation, and period of residence, while economy oriented housing value showed difference according to number of family members, housing type, and home ownership. In detail, men than women, single-income family than double-income family, and detached house resident than flat resident had higher tradition oriented housing value. The younger than the elder, and Seoul resident than outskirts resident had higher economy oriented housing value. Also home owner than tenant, and the higher tradition oriented group had stronger intention to live in cohousing than others.

• Journal of Korea Entertainment Industry Association
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• v.13 no.2
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• pp.279-287
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• 2019

This study is a descriptive study to dentify gerotranscendence, family support, social support, self-esteem, and degree of fear of death and the relationship between old age. Through this study, it provide basic data that can help target elderly people do better in their later years. From June 2018 to October 2018, residents' self-governing centers, senior citizens' centers, and life-long education centers were visited to explain the purpose of the research, and those who voluntarily agreed to the research were selected. The following results were obtained by surveying 50 adults aged 60 or older in Seoul using structured questionnaire. The difference in the level of gerotranscendence, family support, social support, self-esteem, and fear of death according to the general characteristics of the target was analyzed as t-test and ANOVA. The correlation of gerotranscendence, family support, social support, self-esteem, and fear of death in early years of life was analyzed as Pearson correlation coefficient. Among the common traits, age was related to social support and death anxiety, marital status was related to family support, and life satisfaction was related to family support. There was a correlation between old age and fear of death, a correlation between family support and self-esteem, and social support related to self-esteem and fear of death. In conclusion, this study found that early retirement in the old age was associated with fear of death, and it was found that family support in the old age affected self-esteem and satisfaction in life. Future studies need to be conducted on groups of adults in the later years, including the degree of elderly age, satisfaction with living, and relationship between the elderly and the elderly.