• Korean journal of applied entomology
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• v.55 no.2
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• pp.149-160
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• 2016

Temperature-dependent development and fecundity of apterious Rhopalosiphum padi (L.) (Hemiptera: Aphididae) were examined at six constant temperatures (10, 15, 20, 25, 30 and $35{\pm}1.0^{\circ}C$, RH 50-70%, 16L:8D). Development time of nymphs decreased with increasing temperature and ranged from 42.9 days at $10^{\circ}C$ to 4.7 days at $30^{\circ}C$. The nymphs did not develop until adult at $35^{\circ}C$ because the nymphs died during the 2nd instar. The lower threshold temperature and thermal constant of nymph were estimated as $8.3^{\circ}C$ and 101.6 degree days, respectively. The relationships between development rates of nymph and temperatures were well described by the nonlinear model of Lactin 2. The distribution of development times of each stage was successfully fitted to the Weibull function. The longevity of apterious adults decreased with increasing temperature ranging from 24.0 days at $15^{\circ}C$ to 4.3 days at $30^{\circ}C$, with abnormally short longevity of 11.1 days at $10^{\circ}C$. R. padi showed the highest fecundity at $20^{\circ}C$ (38.2) and the lowest fecundity at $10^{\circ}C$ (3.9). In this study, we provided component sub-models for the oviposition model of R. padi: total fecundity, age-specific cumulative oviposition rate, and age-specific survival rate as well as adult aging rate based on the adult physiological age.

• Korea journal of population studies
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• v.14 no.1
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• pp.35-46
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• 1991

Improvements in various health indices have been ushered in, along with soaring economic growth in the last few decades in Korea. Life span of Koreans at present stands at somewhere around age of seventies. It seems of worth to elucidate some facets of health profile of historic Koreans during Yi dynasty encompassing about five hundreds years between the 14th and 19th century. Datas on health of historic Koreans are meager with exception for sovereigns for whom royal archives have been preserved intact through centuries. Though the health environments for monarchs are, no doubt, incomparable to that of the grassroot levels during the same period, health profile of monarchs would facilitate to assess health indices for historic Koreans during Yi dynasty. Arithmetic average of life span of 25 consecutive Kings(omitted the last two Kings under Japanese control) is 44.6 years of age 81 year old for King Yongjo and 16 year old for King Danjong, representing two extremes. The principal causes of death are septicemia, subsequent to infections of soft tissue and ether organs(8 in number, one-thirds of all). Secondly, both epidemic disease and vascular accidents caused deaths of three Kings each. Two kings succumbed to diabets and one suicide. The causes for the remainder, eight kings are hardly ciarified. The monarchs who contributed in establishment of new Yi dynasty with highspirited and disciplined survied beyond their fifties and sixties. In contrast, those who reigned during mid - era of the dynasty at its culmination succumbed to death in their young adulthood, most likely due to their indulgence in court life.

• BMB Reports
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• v.52 no.1
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• pp.24-34
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• 2019

Sirtuin is an essential factor that delays cellular senescence and extends the organismal lifespan through the regulation of diverse cellular processes. Suppression of cellular senescence by Sirtuin is mainly mediated through delaying the age-related telomere attrition, sustaining genome integrity and promotion of DNA damage repair. In addition, Sirtuin modulates the organismal lifespan by interacting with several lifespan regulating signaling pathways including insulin/IGF-1 signaling pathway, AMP-activated protein kinase, and forkhead box O. Although still controversial, it is suggested that the prolongevity effect of Sirtuin is dependent with the level of and with the tissue expression of Sirtuin. Since Sirtuin is also believed to mediate the prolongevity effect of calorie restriction, activators of Sirtuin have attracted the attention of researchers to develop therapeutics for age-related diseases. Resveratrol, a phytochemical rich in the skin of red grapes and wine, has been actively investigated to activate Sirtuin activity with consequent beneficial effects on aging. This article reviews the evidences and controversies regarding the roles of Sirtuin on cellular senescence and lifespan extension, and summarizes the activators of Sirtuin including Sirtuin-activating compounds and compounds that increase the cellular level of nicotinamide dinucleotide.

• Journal of Ginseng Research
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• v.41 no.3
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• pp.277-283
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• 2017

Background: The ginseng berry has various bioactivities, including antidiabetic, anticancer, antiinflammatory, and antioxidative properties. Moreover, we have revealed that the active antiaging component of the ginseng berry, syringaresinol, has the ability to stimulate longevity via gene activation. Despite the many known beneficial effects of ginseng, its effects on skin aging are poorly understood. In this study, we investigated the effects of ginseng and the ginseng berry on one of the skin aging processes, melanogenesis, and age-related pigment lipofuscin accumulation, to elucidate the mechanism of action with respect to antiaging. Methods: The human melanoma MNT1 cell line was treated with ginseng root extract, ginseng berry extract, or syringaresinol. Then, the cells were analyzed using a melanin assay, and the tyrosinase activity was estimated. The Caenorhabditis elegans wild type N2 strain was used for the life span assay to analyze the antiaging effects of the samples. A lipofuscin fluorescence assay was performed during 10 passages with the syringaresinol treatment. Results: A 7-d treatment with ginseng berry extract reduced melanin accumulation and tyrosinase activity more than ginseng root extract. These results may be due to the active compound of the ginseng berry, syringaresinol. The antimelanogenic activity was strongly coordinated with the activation of the longevity gene foxo3a. Moreover, the ginseng berry extract had more potent antiaging effects, caused a life span extension, and reduced lipofuscin accumulation. Conclusion: Taken together, our results suggest that these antimelanogenic effects and antiaging effects of ginseng berry mediate the activation of antioxidation-FoxO3a signaling.

• The Journal of Korean Academic Society of Nursing Education
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• v.15 no.2
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• pp.241-250
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• 2009

Purpose: The purpose of this study was to investigate the relationship of stress, perceived health status and Yangsaeng in Korean part-time college students. Yangsaeng is a traditional health care regimen that incorporates specific principles and methods to promote health and prevent illness, with the aim of improving the health and longevity of life. Method: The subjects of this study were 158 part-time college students in Korea. Data were collected by using a self-reported questionnaire on-line. Analysis of data included descriptive statistics, Pearson's correlation coefficient, t-test, ANOVA and Cronbach's $\alpha$. Result: Statistically significant differences were evident in stress according to age, spouse, job, and income. Statistically significant differences were evident in perceived health status according to gender and job. Statistically significant differences were evident in Yangsaeng according to age, job, and income. Yangsaeng positively related to perceived health status and negatively related to stress. Conclusion: The Yangsaeng oriental health care regimen could lower stress levels and maintain a good health perception. Therefore, Yangsaeng could be recommended as a means of health promotion in Korean part-time college students.

• Journal of Korean Medical classics
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• v.26 no.1
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• pp.1-15
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• 2013

Objective : We tried to seek for conflicts of views among the contents in Sasang Constitutional Medicine and Traditional Medicine based on Huangdi's Internal Classic, and to study about the Range of Lee Je-Ma's Works, therefore finding out the limit of Sasang Constitutional Medicine in view of learning contents and practice of theory. Method : Through the texts of Longevity and Life Preservation in Eastern Medicine, such subjects will be investigated as Lee Je-Ma(李濟馬)'s comments on Huangdi's Internal Classic and views on the herbal medicine, the relations among five viscera(五臟), taeguk(太極), four-constitution(四象), etc. Result : Lee Je-Ma's Sasang Constitutional Medicine does not goes well in harmony with the traditional physiology which is based on the functional five zang system developed in Huangdi's Internal Classic, and is hard to understand because of its four division method rooted in confucius academy. Conclusion : Lee Je-Ma's view of medicine is one of the practical and valuable parts of Korean Medicine, however, its extreme four-division structure theory could be difficult to be accepted as its whole form. This is because he studied himself as a confucian, so that his work might rather be confucian than medical. When he fully devoted himself to Sasang Constitutional Medicine, he already took his age much.

• Natural Product Sciences
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• v.22 no.3
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• pp.201-208
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• 2016

Here in this study, we investigated the lifespan-extending effect and underlying mechanism of methanolic extract of Moringa olelifa leaves (MML) using Caenorhabditis elegans (C. elegans) model system. To define the longevity properties of MML we conducted lifespan assay and MML showed significant increase in lifespan under normal culture condition. In addition, MML elevated stress tolerance of C. elegans to endure against thermal, oxidative and osmotic stress conditions. Our data also revealed that increased activities of antioxidant enzymes and expressions of stress resistance proteins were attributed to MML-mediated enhanced stress resistance. We further investigated the involvement of MML on the aging-related factors such as growth, food intake, fertility, and motility. Interestingly, MML significantly reduced growth and egg-laying, suggesting these factors were closely linked with MML-mediated longevity. We also observed the movement of aged worms to estimate the effects of MML on the health span. Herein, MML efficiently elevated motility of aged worms, indicating MML may affect health span as well as lifespan. Our genetic analysis using knockout mutants showed that lifespan-extension activity of MML was interconnected with several genes such as skn-1, sir-2.1, daf-2, age-1 and daf-16. Based on these results, we could conclude that MML prolongs the lifespan of worms via activation of SKN-1 and SIR-2.1 and inhibition of insulin/IGF pathway, followed by DAF-16 activation.

• Journal of the Korean Professional Engineers Association
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• v.39 no.1
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• pp.70-73
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• 2006

New human sense of value in Knowledge Society of 21th Century is reestablished by that it demanded new thinking for changed today's stage. Reestablishment of new human sense of value is considered by tradition and custom, and now then today's social standard due to focus. Productive human sense of value do to recreate for all round human relations and fertility human life demand it. Korea National Statistical Office(http://www.nso.go.kr-Dec 20. 2005) was officially announced it. that Korean Life Table(2003) presented the reminder of human life and roughly equation model of 'the reminder of human life' is 'Korean average longevity of human life-Present Korean age=About the reminder of human life' on the basic 2003 year. And then we will live a life worth living for our remaining day

• Journal of Korean Academy of Fundamentals of Nursing
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• v.18 no.1
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• pp.79-86
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• 2011

Purpose: The purpose of this study was to investigate the relationship of fatigue and Yangsaeng in Korea. Yangsaeng as a traditional health care regimen for the promotion of health and prevention of illness by means specific principles and methods, whose purpose was to improve longevity and healthy life. Method: The subjects of this study were 196 male adults in Korea. Data were collected by using a self-reported questionnaire and analyzed through descriptive statistics, Pearson's correlation coefficient, t-test, ANOVA and multiple linear regression. Results: There was statistically significant difference in Yangsaeng and fatigue according to age and education. The relationship between Yangsaeng and fatigue had a significant negative correlation. Exercise, sleep, mind Yangsaeng were found to be significant predictors (28%) of fatigue. Conclusion: To prevent fatigue of adults, nurse should focus on the factors identified in this study when she develop nursing intervention programs for health promotion.

• Journal of East-West Nursing Research
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• v.14 no.2
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• pp.8-15
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• 2008

Purpose: Yangsaeng is a traditional health care regimen that incorporates specific principles and methods to promote health and prevent illness, with the aim of improving the health and longevity of life. The present study assessed Yangsaeng and quality of life (QOL-BREF) in Korea. Methods: Data from 346 adults and elderly Koreans was collected by using a self-reported questionnaire. Analysis of the data included descriptive statistics, Pearson's correlation, t-test, ANOVA and Cronbach's ${\alpha}$. Results: Statistically significant differences in QOL-BREF were evident according to the age, job, religion, education level, economic status and positive thinking. Statistically significant differences were evident in Yangsaeng according to religion, education, economic status and positive thinking. Total QOL-BREF positively related to total Yangsaeng. Morality Yangsaeng, exercise Yangsaeng and sleep Yangsaeng were positively related to all QOL-BREF sub-domains. Conclusions: The Yangsaeng oriental health care regimen can improve QOL, and should be recommended as a means of health promotion and QOL in the Korean culture.