• 제목/요약/키워드: the J-integral

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Cloning and Characterization of Porcine Uroplakin II Gene

  • D. N. Kwon;H. K. Shin;C. K. Hwang;D. W. Ok;Kim, J. H.
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2001년도 춘계학술발표대회
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    • pp.19-19
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    • 2001
  • Mammalian urothelium undergoes unique membrane specialization by making the asymmetric unit membrane (AUM) that is covered with the apical cell surface during terminal differentiation. The AUM contains several major integral membrane proteins including uroplakin Ia, Ib, II and III. The genes for uroplakins have been cloned from humans and mice, but not from porcine. In this study, we report the cloning of the UPII genomic DNA, which codes for the full length open reading frame for the uroplakin II protein. The deduced amino acid sequence encodes of a hydrophobic NH$_2$-terminal peptide, a prosequence, and a mature protein. The prosequence contains three potential N-glycosylation sites and a RGRR cleavage site that may be involved in uroplakin II processing and maturation. Northern and immunohistochemistry analyses showed that the porcine UPII gene is only expressed in urothelium and that the protein was specifically localized in urothelial superficial cells. A 2kb of upstream in the promoter sequence contains multiple transcription factor binding sites, including GC-box, SPI, AP2, and GATA-box sites, but not for TATA or CAAT-box sequences. Comparison of the porcine UPII promoter sequence with that of the murine by MEME system presented two conserved motifs, suggesting a cis-acting regulatory role for the conserved sequences. Sequence homology between two species in motif A and B was 79% and 80% respectively, although their relative locations were different. During the gestation, mouse bladder at estrus stages and day 10 after parturition showed higher UPII expression, while showed lower expression at peri-implantation stage. Taken together, our results showed that the porcine UPII gene was expressed highly and specifically in the bladder urothelium and that steroid hormones for implantation changed the expression of UPII in the bladder, although the biological significance of UPII remains to be not determined.

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Preliminary design of control software for SDSS-V Local Volume Mapper Instrument

  • Kim, Changgon;Ji, Tae-geun;Ahn, Hojae;Yang, Mingyeong;Lee, Sumin;Kim, Taeeun;Pak, Soojong;Konidaris, Nicholas P.;Drory, Niv;Froning, Cynthia S.;Hebert, Anthony;Bilgi, Pavan;Blanc, Guillermo A.;Lanz, Alicia E.;Hull, Charles L;Kollmeier, Juna A.;Ramirez, Solange;Wachter, Stefanie;Kreckel, Kathryn;Pellegrini, Eric;Almeida, Andr'es;Case, Scott;Zhelem, Ross;Feger, Tobias;Lawrence, Jon;Lesser, Michael;Herbst, Tom;Sanchez-Gallego, Jose;Bershady, Matthew A;Chattopadhyay, Sabyasachi;Hauser, Andrew;Smith, Michael;Wolf, Marsha J;Yan, Renbin
    • 천문학회보
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    • 제46권1호
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    • pp.39.1-39.1
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    • 2021
  • The Local Volume Mapper(LVM) project in the fifth iteration of the Sloan Digital Sky Survey (SDSS-V) will produce large integral-field spectroscopic survey data to understand the physical conditions of the interstellar medium in the Milky Way, the Magellanic Clouds, and other local-volume galaxies. We are developing the LVM Instrument control software. The architecture design of the software follows a hierarchical structure in which the high-level software packages interact with the low-level and mid-level software and hardware components. We adopt the spiral software development model in which the software evolves by iteration of sequential processes, i.e., software requirement analysis, design, code generation, and testing. This spiral model ensures that even after being commissioned, the software can be revised according to new operational requirements. We designed the software by using the Unified Modeling Language, which can visualize functional interactions in structure diagrams. We plan to use the SDSS software framework CLU for the interaction between components, based on the RabbitMQ that implemented the Advanced Message Queuing Protocol (AMQP).

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매트릭스 컨버터로 구동되는 유도전동기의 직접토크제어를 위한 모델예측제어 기반의 SVM 기법 (Model Predictive Control for Induction Motor Drives Fed by a Matrix Converter)

  • 최우진;이은실;송중호;이영일;이교범
    • 제어로봇시스템학회논문지
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    • 제20권9호
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    • pp.900-907
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    • 2014
  • This paper proposes a MPC (Model Predictive Control) method for the torque and flux controls of induction motor. The proposed MPC method selects the optimized voltage vector for the matrix converter control using the predictive modeling equation of the induction motor and cost function. Hence, the reference voltage vector that minimizes the cost function of the torque and flux error within the control period is selected and applied to the actual system. As a result, it is possible to perform the torque and flux control of induction motor using only the MPC controller without a PI (Proportional-Integral) or hysteresis controller. Even though the proposed control algorithm is more complicated and has lots of computations compared with the conventional MPC, it can perform torque ripple reduction by synthesizing voltage vectors of various magnitude. This feature provides the reduction of amount of calculations and the improvement of the control performance through the adjustment of the number of the unit vectors n. The proposed control method is validated through the PSIM simulation.

치위생과 학생의 전문직 자아개념과 임상실습 만족도와의 관계 연구 (A study on the professional self-concept of dental hygiene students and their satisfaction level with clinical practice)

  • 강용주
    • 한국치위생학회지
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    • 제9권1호
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    • pp.73-84
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    • 2009
  • The purpose of this study was to examine the professional self-concept of dental hygiene students, their satisfaction level with clinical practice and the correlation of the two factors. The subjects in this study were 129 dental hygiene seniors at a college located in the city of J. The selected students had been engaged in a 16-week clinical practice. The findings of the study were as follows: 1. The dental hygiene students investigated got a mean of 3.34 out of possible five points on professional self-concept. As for the subfactors of professional self-concept, they got 3.75, 3.38 and 2.87 respectively on communication, professional work handling and satisfaction level. 2. They got a mean of 3.29 out of possible five points on satisfaction level with clinical practice. As to the subfactors of the satisfaction level, they gave 3.60, 3.50, 3.46, 3.04 and 2.83 to environments for practice, the content of practice, supervision, the length of practice and evaluation respectively. 3. In regard to the relationship of general characteristics to professional self-concept, satisfaction level with the major and social perception of dental hygienist made significant differences to professional self-concept. 4. As for connections between the general characteristics and satisfaction level with clinical practice, satisfaction with clinical practice was significantly different according to satisfaction with the major, satisfaction with the amount of practice and satisfaction with social perception of dental hygienist. 5. There was a significantly positive correlation between professional self-concept and satisfaction level with clinical practice(r=.383, p=.001). In conclusion, how much dental hygienists who are trained to be a dental hygienist are gratified with clinical practice is one of integral factors to affect their development of professional self-concept. Therefore prolonged research efforts should be directed into determining in which way clinical practice should be implemented to develop the professional self-concept of would-be dental hygienists and how to raise their satisfaction with clinical practice.

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이축하중을 받는 십자형 시편의 파괴인성 및 구속효과 평가 (Evaluation of Fracture Toughness and Constraint Effect of Cruciform Specimen under Biaxial Loading)

  • 김종민;김민철;이봉상
    • 한국압력기기공학회 논문집
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    • 제12권1호
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    • pp.62-69
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    • 2016
  • Current guidance considers that uniaxially loaded specimen with a deep crack is used for the determination of the ductile-to-brittle transition temperature. However, reactor pressure vessel is under biaxial loading in real and the existence of deep crack is not probable through periodic in-service-inspection. The elastic stress intensity factor and the elastic-plastic J-integral which were used for crack-tip stress field and fracture mechanics assessment parameters. The difference of the loading condition and crack geometry can significantly influence on these parameters. Thus, a constraint effect caused by differences between standard specimens and a real structure can over/underestimate the fracture toughness, and it affects the results of the structural integrity assessment, consequentially. The present paper investigates the constraint effects by evaluating the master curve $T_0$ reference temperature of PCVN (Pre-cracked Charpy V-Notch) and small scale cruciform specimens which was designed to simulate biaxial loading condition with shallow crack through the fracture toughness tests and 3-dimensional elastic-plastic finite element analyses. Based on the finite element analysis results, the fracture toughness values of a small scale cruciform specimen were estimated, and the geometry-dependent factors of the cruciform specimen considered in the present study were determined. Finally, the transferability of the test results of these specimens was discussed.

THE IMPACT OF POWER COEFFICIENT OF REACTIVITY ON CANDU 6 REACTORS

  • Kastanya, D.;Boyle, S.;Hopwood, J.;Park, Joo Hwan
    • Nuclear Engineering and Technology
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    • 제45권5호
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    • pp.573-580
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    • 2013
  • The combined effects of reactivity coefficients, along with other core nuclear characteristics, determine reactor core behavior in normal operation and accident conditions. The Power Coefficient of Reactivity (PCR) is an aggregate indicator representing the change in reactor core reactivity per unit change in reactor power. It is an integral quantity which captures the contributions of the fuel temperature, coolant void, and coolant temperature reactivity feedbacks. All nuclear reactor designs provide a balance between their inherent nuclear characteristics and the engineered reactivity control features, to ensure that changes in reactivity under all operating conditions are maintained within a safe range. The $CANDU^{(R)}$ reactor design takes advantage of its inherent nuclear characteristics, namely a small magnitude of reactivity coefficients, minimal excess reactivity, and very long prompt neutron lifetime, to mitigate the demand on the engineered systems for controlling reactivity and responding to accidents. In particular, CANDU reactors have always taken advantage of the small value of the PCR associated with their design characteristics, such that the overall design and safety characteristics of the reactor are not sensitive to the value of the PCR. For other reactor design concepts a PCR which is both large and negative is an important aspect in the design of their engineered systems for controlling reactivity. It will be demonstrated that during Loss of Regulation Control (LORC) and Large Break Loss of Coolant Accident (LBLOCA) events, the impact of variations in power coefficient, including a hypothesized larger than estimated PCR, has no safety-significance for CANDU reactor design. Since the CANDU 6 PCR is small, variations in the range of values for PCR on the performance or safety of the reactor are not significant.

High Mass X-ray Binary and IGOS with IGRINS

  • Chun, Moo-Young;Moon, Dae-Sik;Jeong, Ueejeong;Yu, Young Sam
    • 천문학회보
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    • 제39권2호
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    • pp.95-95
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    • 2014
  • The mass measurement of neutron stars or black holes is of fundamental importance in our understanding of the evolution of massive stars and core-collapse supernova explosions as well as some exotic physics of the extreme conditions. Despite the importance, however, it's very difficult to measure mass of these objects directly. One way to do this, if they are in binary systems, to measure their binary motions (i.e., Doppler shifts) which can give us direct information on their mass. Recently many new highly-obscured massive X-ray binaries have been discovered by new hard X-ray satellites such as INTEGRAL and NuSTAR. The new highly-obscured massive X-ray binaries are faint in the optical, but bright in the infrared with many emission lines. Based on the near-infrared spectroscopy, one can first understand the nature of stellar companions to the compact objects, determining its spectral types and luminosity classes as well as mass losses and conditions of (potential) circumstellar material. Next, spectroscopic monitoring of these objects can be used to estimate the mass of compact objects via measuring the Doppler shifts of the lines. For the former, broad-band spectroscopy is essential; for the latter, high-resolution spectroscopy is critical. Therefore, IGRINS appears to be an ideal instrument to study them. An IGRINS survey of these new highly-obscured massive X-ray binaries can give us a rare opportunity to carry out population analyses for understanding the evolution of massive binary systems and formation of compact objects and their mass ranges. In this talk, we will present a sample near-infrared high resolution spectra of HMXB, IGR J19140+0951 and discuss about its spectral feature. These spectra are obtained on 13th July, 2014 from IGRINS commissioning run at McDonald 2.7m telescope. And at final, we will introduce the upgrade plan of IGRINS Operation Software (IGOS), to gather the input from IGRINS observer.

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동적 특성을 고려한 6축 로봇의 서보 파라미터 튜닝에 관한 연구 (The Study of Servo-Parameter Tuning Technique for 6-Axes Articulated Robot Manipulator in Consideration of Dynamic Characteristics)

  • 정원지;김효곤;이춘만;홍대선;박승규;서영교;이기상
    • 한국공작기계학회논문집
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    • 제16권5호
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    • pp.1-6
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    • 2007
  • This paper presents a new experimental Servo-Parameter tuning technique for a 6-axes articulated robot manipulator, especially considering robot's dynamics. First of all, investigation for proportional gain of velocity control loop by using a Dynamic Signal Analyzer(DSA) is performed. Using the FUNCTION characteristic of DSA based on the Bode plot, the Bode plot of open loop transfer function can be obtained. In turn, the integral gain of a servo controller can be found out by using the integration time constant extracted from the Bode plot of open loop transfer function. In the meanwhile, the positional gain of the servo controller can be obtained by using the Bode plot of the closed loop transfer function. Using the experimental gain tuning technique proposed in this paper, the testing linear motion of DR6-II robot has been shown to be more accurate rather than the motion with a conventional(empirical) gain tuning technique in Doosan Mecatec Co., Ltd., by improving the dynamic response of the robot as well as synchronizing each joint velocity according to the positional command of an end-effector.

광결상계의 초분해능 (Superresolution of Optical Imaging System)

  • 조영민;김종태;이상수
    • 한국광학회지
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    • 제5권3호
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    • pp.349-355
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    • 1994
  • Rayleigh의 분해능 한계 $\epsilon_R$보다 작은 선폭 $\epsilon_0$을 분해할 수 있는 광결상계사 이론적으로 취급되었고, 이어서 초분해능을 지니는 광학계가 제시되었다. 먼저 초분해능을 역변환 문제로 취급하여 초분해능 회절상의 진폭 임펄스 함수를 주는 적분방정식을 도입하고 매개변수 $\beta$(양정수)에 따라서 진폭 임펄스 함수의 반치폭이 조사되었다. 이 초분해능 광학계의 구경함수의 진폭 분포가 변조되었고 또 구경에서 나가는 Huygens 파동의 위상도 Holography로 변조되었다. 이들의 변조를 위하여 이용된 광변조 소자가 제시되었다. 초미세 광리소그라피에 유용한 결론을 얻었다.

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Comparison of Image Uniformity with Photon Counting and Conventional Scintillation Single-Photon Emission Computed Tomography System: A Monte Carlo Simulation Study

  • Kim, Ho Chul;Kim, Hee-Joung;Kim, Kyuseok;Lee, Min-Hee;Lee, Youngjin
    • Nuclear Engineering and Technology
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    • 제49권4호
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    • pp.776-780
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    • 2017
  • To avoid imaging artifacts and interpretation mistakes, an improvement of the uniformity in gamma camera systems is a very important point. We can expect excellent uniformity using cadmium zinc telluride (CZT) photon counting detector (PCD) because of the direct conversion of the gamma rays energy into electrons. In addition, the uniformity performance such as integral uniformity (IU), differential uniformity (DU), scatter fraction (SF), and contrast-to-noise ratio (CNR) varies according to the energy window setting. In this study, we compared a PCD and conventional scintillation detector with respect to the energy windows (5%, 10%, 15%, and 20%) using a $^{99m}Tc$ gamma source with a Geant4 Application for Tomography Emission simulation tool. The gamma camera systems used in this work are a CZT PCD and NaI(Tl) conventional scintillation detector with a 1-mm thickness. According to the results, although the IU and DU results were improved with the energy window, the SF and CNR results deteriorated with the energy window. In particular, the uniformity for the PCD was higher than that of the conventional scintillation detector in all cases. In conclusion, our results demonstrated that the uniformity of the CZT PCD was higher than that of the conventional scintillation detector.