• Clinical and Experimental Reproductive Medicine
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• 제48권3호
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• pp.221-228
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• 2021

Objective: This study investigated the effect of crocin in methylglyoxal (MGO)-induced diabetic male mice. Methods: Seventy 1-month-old male NMRI mice weighing 20-25 g were divided into seven groups (n=10): sham, MGO (600 mg/kg/day), MGO+crocin (15, 30, and 60 mg/kg/day), MGO+metformin (150 mg/kg/day), and crocin (60 mg/kg/day). MGO was administered orally for 30 days. Starting on day 14, after confirming hyperglycemia, metformin and crocin were administered orally. On day 31, plasma and tissue samples were prepared for experimental assessments. Results: Blood glucose and insulin levels in the MGO group were higher than those in the sham group (p<0.001), and decreased in response to metformin (p<0.001) and crocin treatment (not at all doses). Testis width and volume decreased in the MGO mice and improved in the crocin-treated mice (p<0.05), but not in the metformin group. Superoxide dismutase levels decreased in diabetic mice (p<0.05) and malondialdehyde levels increased (p<0.001). Crocin and metformin improved malondialdehyde and superoxide dismutase. Testosterone (p<0.001) and sperm count (p<0.05) decreased in the diabetic mice, and treatment with metformin and crocin recovered these variables. Luteinizing hormone levels increased in diabetic mice (p<0.001) and crocin treatment (but not metformin) attenuated this increase. Seminiferous diameter and height decreased in the diabetic mice and increased in the treatment groups. Vacuoles and ruptures were seen in diabetic testicular tissue, and crocin improved testicular morphology (p<0.01). Conclusion: MGO increased oxidative stress, reduced sex hormones, and induced histological problems in male reproductive organs. Crocin and metformin improved the reproductive damage caused by MGO-induced diabetes.

• Imaging Science in Dentistry
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• 제49권1호
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• pp.45-51
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• 2019

Purpose: To determine the prevalence of concha bullosa (CB) and nasal septal deviation (NSD) and their impact on maxillary sinus volume (MSV). Materials and Methods: Cone-beam computed tomographic (CBCT) images of 106 Emirati people were used in this study. The direction and angle of septal deviation were calculated. The presence of CB, which could be unilateral, contralateral, or bilateral in relation to the direction of NSD, was also recorded. MSV was measured using reconstructed Digital Imaging and Communication in Medicine images on Dolphin 3D imaging software version 11.8 premium (Dolphin Imaging, Chatsworth, CA, USA). P values<0.05 were considered to indicate statistical significance. Results: CB was detected in 37.7% of the sample; 20.7% of the sample showed single unilateral CB and 16.6% had single bilateral CB. NSD was seen in 74.5% of the sample. In the participants with CB, 45.5% showed mild deviation, 34.4% showed moderate deviation, and only 12.5% showed severe septal deviation. CB, but not NSD, was associated with significantly higher MSV on the affected side (P=0.001). Conclusion: Although NSD was observed in more than two-thirds of the sample and CB was present in more than one-third of the sample, only CB had a significant impact on MSV.

• Structural Engineering and Mechanics
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• 제53권5호
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• pp.881-896
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• 2015

In this study, a method for fatigue performance estimation of deepwater steel catenary riser (SCR) under short-term vortex-induced vibration was investigated for selected S-N curves. General tendency between S-N curve capacity and fatigue performance was analysed. SCRs are generally used to transport produced oil and gas or to export separated oil and gas, and are exposed to various environmental loads in terms of current, wave, wind and others. Current is closely related with VIV and it affects fatigue life of riser structures significantly. In this regards, the process of appropriate S-N curve selection was performed in the initial design stage based on the scale of fabrication-related initial imperfections such as welding, hot spot, crack, stress concentration factor, and others. To draw the general tendency, the effects of stress concentration factor (SCF), S-N curve type, current profile, and three different sizes of SCRs were considered, and the relationship between S-N curve capacity and short-term VIV fatigue performance of SCR was derived. In case of S-N curve selection, DNV (2012) guideline was adopted and four different current profiles of the Gulf of Mexico (normal condition and Hurricane condition) and Brazil (Amazon basin and Campos basin) were considered. The obtained results will be useful to select the S-N curve for deepwater SCRs and also to understand the relationship between S-N curve capacity and short-term VIV fatigue performance of deepwater SCRs.

• 교육녹색환경연구
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• 제6권1호
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• pp.1-24
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• 2007

Public library is established on impartial accessibility of any distinction as their sex, age, financial status, etc. The function of public library is not only to accumulate materials and offer information but also minimize gulf between the rich and the poor by knowledge possession, which is realized by important means to intercept exclusive possession and power in knowledge pose-industrial society. As it is judged that most public library is established to individual building with thousands of cost, it is judged of obstacles to Increase library buildings. The purpose of this study is try to find the way to Increase In number of public library In Seoul by interaction local education-cultural facilities. The result from this study, the user rate of public library is influenced by number of buildings and accessibility of traffic and public library can improve efficiency by substantial operation by basic function for all age group. The target population of Seoul public library sizes by decuple of advanced countries because of difficulty of accessibility, so it needs to make it small scale and also can offer self-regulation learning, materials and life-long learning programs because generally public library's utilization purpose is different by age. As school in Seoul amounts to 25 times of public library by about 1,200 buildings and can function of lifelong education center with a school library, cultural center and other composition buildings, so school facilities may use as a public library for local residents.

• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.17-22
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• 2016

Colorectal cancer is a major cause of mortality worldwide. Fecal occult blood testing has proven a very effective screening tool for early detection and mortality reduction. The aim of this study was to determine predictors factors related to fecal occult blood testing using the Health Belief Model method among residents of Bushehr, Iran. A cross sectional study was performed on a sample of 600 men and women more than 50 years of age. The sample was selected by a convenience method from patients referred to public and private laboratories throughout the city. Each subject filled out a questionnaire which was designed and developed based on Health Belief Model constructs. Statistical analysis was conducted using ANOVA, T-test, chi-square test, and logistic regression. Fecal occult blood tests were performed on 179 (29.8%) out of 600 subjects, of which 95 patients (58.1%) did a periodic examination test and 84 patients (46.9%) had a doctor's advice for testing. According to the logistic regression model, the perceived barriers (P=0.0, Exp(B)= 0.3), perceived benefits (P<0.01, Exp(B)= 1.9) and self-efficacy (P<0.01, Exp(B)= 1.6) were predictive factors related to occult blood testing among subjects. The results showed that reducing people's perception of barriers to testing, increasing perceived benefits of screening, and reinforcing self efficacy can have major effect in increasing the rate of fecal occult blood screening for colorectal cancer prevention.

• Steel and Composite Structures
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• 제48권2호
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• pp.179-190
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• 2023

Many recent attempts have sought accurate prediction of pile pullout resistance (P_ul) using classical machine learning models. This study offers an improved methodology for this objective. Adaptive neuro-fuzzy inference system (ANFIS), as a popular predictor, is trained by a capable metaheuristic strategy, namely equilibrium optimizer (EO) to predict the P_ul. The used data is collected from laboratory investigations in previous literature. First, two optimal configurations of EO-ANFIS are selected after sensitivity analysis. They are next evaluated and compared with classical ANFIS and two neural-based models using well-accepted accuracy indicators. The results of all five models were in good agreement with laboratory P_uls (all correlations > 0.99). However, it was shown that both EO-ANFISs not only outperform neural benchmarks but also enjoy a higher accuracy compared to the classical version. Therefore, utilizing the EO is recommended for optimizing this predictive tool. Furthermore, a comparison between the selected EO-ANFISs, where one employs a larger population, revealed that the model with the population size of 75 is more efficient than 300. In this relation, root mean square error and the optimization time for the EO-ANFIS (75) were 19.6272 and 1715.8 seconds, respectively, while these values were 23.4038 and 9298.7 seconds for EO-ANFIS (300).

• 한국정보통신학회논문지
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• 제7권3호
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• pp.355-362
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• 2003

본 논문에서는 완전 동기된 수신신호가 되도록 다이버시티의 브랜치간에 발생하는 위상차를 PLL의 이득값을 조절하여 보정할 경우, 시스템의 복잡도를 줄이면서 성능이 좋은 하이브리드 SC/MRC 다이버시티 방식이 적용된 DS/CDMA 시스템의 성능분석을 하였다. 또한, 이동통신 환경에 대한 채널 환경 모델로 나카가미-m 페이딩 채널 환경을 채택하였으며, 나카가미 페이딩 지수에 따른 DS/CDMA 시스템에서 고려사항인 사용자, 프로세싱이득 및 경로수를 고려한 하이브리드 SC/MRC 다이버시티에 대한 시뮬레이션을 수행하였다. 분석결과 페이딩 환경에 따라 완전히 위상이 일치하도록 하기 위한 PLL의 이득값이 존재함을 알 수 있었다 이는 하이브리드 SC/MRC 다이버시티 방식이 적용된 DS/CDMA 시스템의 성능 개선을 위해 적절한 PLL 이득값을 조절하여 성능의 개선을 이룰수 있음을 확인하였다. 결과적으로, 하이브리드 SC/MRC 다이버시티 방식이 적용된 DS/CDMA 시스템을 실제 통신 환경에서 적용할 경우, 완전 동기된 수신 신호가 되기 위해 페이딩 지수에 따라 조금의 차이는 있지만 PLL 이득 값이 5dB이상 되어야 함을 확인하였다.

• BMB Reports
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• 제37권2호
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• pp.213-222
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• 2004

A randomly amplified polymorphic DNA (RAPD) analysis was used to identify the species- and population-specific markers of abalone; Haliotis asinina, H. ovina, and H. varia in Thai waters. Fifteen species-specific and six population-specific RAPD markers were identified. In addition, an 1650 bp band (UBC195) that was restricted to H. ovina from the Gulf of Thailand (east) was also found. All of the specific RAPD markers were cloned and sequenced. Twenty pairs of primers were designed and specificity-tested (N = 12 and 4 for target and non-target species, respectively). Seven primer pairs (CUHA1, 2, 4, 11, 12, 13, and 14) were specifically amplified by H. asinina DNA, whereas a single pair of primers showed specificity with H. ovina (CUHO3) and H. varia (CUHV1), respectively. Four primer pairs, including CUHA2, CUHA12, CUHO3, and CUHV1, were further examined against 216 individuals of abalone (N = 111, 73, and 32, respectively). Results indicated the species-specific nature of all of them, except CUHO3, with the sensitivity of detection of 100 pg and 20 pg of the target DNA template for CUHA2 and CUHA12 and CUHV1, respectively. The species-origin of the frozen, ethanol-preserved, dried, and boiled H. asinina specimens could also be successfully identified by CUHA2.

• 대한전자공학회논문지TE
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• 제39권2호
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• pp.95-103
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• 2002

지난 걸프전에서 보아 익히 알 수 있듯이 최근 전장에 배치되는 무기체계들은 고도로 복잡 다양해지고 있으며, 모든 무기체계들은 전자${\cdot}$정보화되어 모든 장비들이 네트워크로 연결되고 연동이 가능하게 설계되는 추세이다. 특히 구축함이나 호위함, 초계함, 잠수함 등과 같은 군함에 탑재되는 모든 함상 장비들은 컴뱃 시스템 데이터 버스(Ethernet)와 같은 네트워크로 연결되어 컴뱃 시스템에 의해 통제 운영되고 있다. 이러한 관점에서 볼 때 군함 네트워크의 정상 동작 상태 유지는 전장에서 가장 중요한 요소라 할 수 있다. 따라서, 본 논문에서는 함정의 탑재 장비간 네트워크 관리방안에 대해 제시하고, 특히 SNMP 기반 POP 폴링 기법의 구축함(DX : Destroyer, Experimental) 탑재 장비 네트워크 관리 시스템 구조설계안을 제시하며, 시뮬레이션을 통해 사용율의 변화를 측정한다.

• 대한원격탐사학회지
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• 제26권2호
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• pp.175-188
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• 2010

세계 최초로 정지 상태로 해색을 관측하는 정지궤도해색탑재체(GOCI, Geostationary Ocean Color Imager) 값의 보정을 위해서는 기존의 방법이 아닌 새로운 방법이 요구된다. 본 연구에서는 GOCI의 특별한 특성에 맞는 새로운 대기보정 방법과 양방향성 광반사 분포함수(BRDF, Bidirectional Reflectance Distribution Function) 보정 방법을 소개하고자 한다. GOCI의 대기보정을 위해서 스펙트럼 형태 조화기법(SSMM, Spectral Shape Matching Method)과 Sun Glint Correction Algorithm(SGCA)을 개발하였고, BRDF 보정을 위하여 해수의 고유광특성(IOP, Inherent Optical Property) 값을 이용하는 새로운 방법을 개발하였다. 각 방법은 한반도 주변 해역을 관측한 Sea Viewing Wide Field-of-view Sensor(SeaWiFS) 위성영상을 이용하여 적용하였다. 클로로필 농도 분포 영상을 만들어 본 결과 기존의 방법으로 얻기 어려웠던 탁도높은 해역과 에어로졸의 영향을 많이 받는 지역에서 보다 정확한 자료를 얻을 수 있었다.