• 대한한방내과학회지
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• 제41권5호
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• pp.911-925
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• 2020

Objectives: The purpose of this study was to report a case of a patient with advanced gastric cancer with peritoneal metastasis treated with chemotherapy and Korean medicine Methods: A patient with advanced gastric cancer with peritoneal metastasis was treated with Xeloda/cisplatin since April 2019. The cycle was repeated every three weeks for a total of 11 times. At the same time, the patient was treated with Korean medicine. The tumor size was measured by computed tomography (CT) and esophagogastroduodenoscopy (EGD). Adverse events were evaluated by the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE), version 5.0. Results: After treatment with Xeloda/cisplatin and Korean medicine for nine months, the extent of the proximal portion of the primary tumor and the size and number of multiple nodules around the stomach decreased and the cancer cells with peritoneal metastasis disappeared. The symptoms of discomfort and physical activity were gradually improved. As a result, the patient underwent conversion surgery. Conclusions: This case study suggests that the combination of chemotherapy and Korean medicine may contribute to the reduction in tumor size as well as the improvement in the quality of life.

• 대한한방내과학회지
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• 제40권4호
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• pp.723-729
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• 2019

Objective: This study was aimed at reporting on a patient with repeated recurrence of metastatic colorectal cancer treated with traditional Korean medicine (TKM) alone after operation and chemotherapy. Method: The patient with metastatic colorectal cancer received tumor resections four times and perioperative chemotherapy for repeated recurrence from February 2013 until March 2015. TKM, which included Gunchil-dan and Haeam-dan, was administered until June 2019 to prevent additional relapses. Results: After 49 months of TKM treatment, there was no tumor recurrence. A no evidence of disease (NED) state was maintained from March 2015 to June 2019. Recurrence-free survival (RFS) was shown for 49 months and overall survival (OS) for 78 months. Serious adverse events evaluated according to the Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0 were not identified. This study suggested that TKM with herbal medicine including aRVS might prolong survival and inhibit recurrence of tumors in patients with metastatic colorectal cancer.

• 과학기술학연구
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• 제14권1호
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• pp.139-175
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• 2014

지난 이십여 년 간 한국의 전문가 집단과 시민사회는 맞춤의학(personalized medicine)의 실현 여부와 그 효용을 둘러싸고 갑론을박을 벌여왔다. 이러한 논의들은 주로 맞춤의학이 실현가능한 약속인지 아니면 단순한 과장광고(hype)인지에 주로 초점을 맞추어 이루어졌는데, 이 글은 이러한 논의들이 '맞춤의학'이라는 용어의 '통시적 혼종성'과 '공시적 다의성'을 놓치고 있음을 지적한다. 본 연구는 맞춤의학을 행위자들에 의해 이용되는 수사적 도구(rhetorical device) 혹은 수사적 존재(rhetorical entity)로 보기를 제안하는 선행 연구를 좇아, 1998년부터 2013년까지 이루어진 약 9천 건의 국내 언론 보도 내용을 분석한다. 이를 바탕으로 한국에서는 '맞춤의학'이라는 용어가 기술과학 발전의 역사적 맥락에 맞추어 서로 다른 사회세계에 속하는 행위자들에 의해, 건강기능식품, 의료정보제공, 원격진료, 재생의학, 줄기세포연구, 환자중심진료, 질병중심임상처방, 사상체질의학을 가리키는 것으로 끊임없이 재정의 되어 왔음을 보이고자 한다. 이를 통해 이 글은 맞춤의학 거버넌스에 대한 정책적 제언과 이론적 기여의 두 가지를 시도한다. 정책적 제언과 관련해서 이 글은 현재 정책 연구들이 역사적 다의성을 고려하지 않은 결과 각기 다른 대상들을 맞춤의학으로 설정하고 분석을 전개하고 있으며, 맞춤 의학을 보편적인 과학적 실재로 가정함에 따라 미국의 ELSI 연구 결과들을 한국 상황의 분석에 그대로 적용하고 있음을 지적한다. 이론적 기여와 관련해서 이 글은 맞춤의학과 같은 신기술에 결부되는 정치적 함의를 검토할 수 있는 도구로 '기표-정치(signifiant-politics)'의 개념을 제시한다. 하나의 용어 단일한 기표가 다양한 의미체계 안에서 서로 다른 의미로 사용되는 현상은 이전에 세상에 존재하지 않던 새로운 기술과학이 혁신을 통해 등장하였을 때 관찰되는 것으로, 그를 지시하는 기표로서 언어가 갖는 본질적 결여가 파생한 결과로 볼 수 있다. 신기술 분야에서 정책결정과 거버넌스가 중요한 것은 이 이유 때문이다. 신기술정책은 바로 이러한 기표의 무한한 흐름과 미끄러짐을 정박(碇泊)시키는, 의미의 고정점이자 기표의 누빔점(point de capiton, quilting point)이 된다는 점에서 상징계에서 중대한 의미를 지닌다. 이 사례연구에서 볼 수 있었듯이, 기술정책 등의 사회적 합의가 누빔점을 제공하기 이전까지 신기술의 기표가 갖는 의미의 미끄러짐을 활용하는 행위자들의 특징을 기표-정치(signifiant-politics)라고 부를 것을 조심스럽게 제안하고자 한다.

• 대한암한의학회지
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• 제25권1호
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• pp.1-9
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• 2020

Objective: The purpose of this study is to report improvement of symptoms after lobectomy of male breast cancer lung metastasis treated with Korean Medicine based Integrative Cancer Treatment (ICT). Methods: A male left breast cancer patient diagnosed with metastasis on lung at July 2019. After Video assisted thoracic surgery (VATS) left lower lobe (LLL) lobectomy and En bloc wedge resection the patient visited the Daejeon korean medicine hospital of Daejeon university East West Cancer Center (EWCC) to treat operation-site (op-site) pain, dysphagia, anorexia with Korean Medicine Treatment. The patient was treated with Korean Medicine based ICT for an approximately 20 days. The clinical outcomes were measured by National Cancer Institute Common Terminology Criteria for Adverse Event (NCI-CTCAE), Numeral rating scale (NRS) and Eastern Cooperative Oncology Group (ECOG). The safety of treatment was verified by blood tests. Results: After treatment, op-site pain was improved from NRS 9 to 6, dysphagia and anorexia were relieved from NRS 9 to 2. And ECOG score of the patient was improved from grade 2 to 1. Conclusion: This case study suggests that Korean Medicine based ICT may help to improve post operative sequelae in metastatic lung cancer patient.

• 대한암한의학회지
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• 제27권1호
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• pp.1-12
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• 2022

Objectives: To report recurrent pancreatic cancer treated by Korean medicine based-integrated oncology treatment, who is improved quality of life without progression of cancer Method: A 63-year-old female patient diagnosed with recurrent pancreatic cancer in April, 2022 received Chemotherapy with Korean medicine based integrative oncology treatment. Radiologic outcome was assessed by Abdomen Computed Tomography (CT) based on Response Evaluation Criteria In Solid Tumors (RECIST). Clinical outcomes were assessed by National Cancer Institute Common Terminology Criteria for Adverse Event (NCI-CTCAE), Eastern Cooperative Oncology Group (ECOG), Numeric Rating Scale (NRS) Result: During 2months of treatment, Cancer size was stable in Abdominal CT. Chief complaints, Abdominal pain and dyspepsia, were improved and ECOG score was improved from grade 2 to 1. There were no toxicity on laboratory test and no side effects of grade 3 or higher on NCI-CTCAE. Conclusion: This report shows that Korean medicine based integrative oncology treatment might contribute to synergetic effect to Chemotherapy and improvement of quality of life

• 대한암한의학회지
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• 제23권2호
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• pp.11-25
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• 2018

Objective: The purpose of this study is to report the case of a patient with non-small cell lung cancer (NSCLC) with Programmed cell death protein 1 (PD-1) mutation treated by Integrative Medicine Therapy (IMT). Methods: A patient with metastatic NSCLC received pembrolizumab 200mg intravenously for every 3 weeks from July 2017. Repeat cycle every 3 weeks since July 2017. The patient has been treated with Integrative Medicine Therapy (IMT) since December 2016. The tumor size was measured by computed tomography (CT) and magnetic resonance imaging(MRI). Adverse events were evaluated by the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE), version 5.0. Results: After combined treatment, the extent of proximal portion of primary tumor in the left lower lobe was decreased and disease status was stable radiologically. No evidence of newly developed metastatic lesions in the brain since May 2017. The patient did not experience any adverse event according to NCI-CTCAE ver. 5.0. Conclusion: This case study suggests that Integrative Medicine Therapy (IMT) may contribute to tumor response, in conjunction with Pembrolizumab on the treatment of patients with NSCLC.

• 한국의사학회지
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• 제23권2호
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• pp.23-36
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• 2010

In this paper, this writer looked into the initial law and fortification, which are two of the most important phonetic changes of Sino-Korean words. Pronunciation and inscription rules of Oriental Medical terminologies have also been studied. Moreover, several problems of meaningful rendering of Oriental Medical Chinese terminologies into Korean have been looked into. As a result, the following conclusions could be drawn. 1. The initial law only applies to Sino-Korean words that consist of more than one syllable. It does not apply to words borrowed from foreign languages. Especially, compound words like Jang-ssi-yu-gyeong(張氏類經) or Im-sin-yuk-hyeol(姙娠衄血) consist of already existing words such as Jang-ssi(張氏), Yu-gyeong(類經), Im-sin(姙娠), and Yuk-hyeol(衄血), and thus the initial law applies to these words. They are inscribed and pronounced 'Jang-ssi-yu-gyeong' and 'Im-sin-yuk-hyeol'. 2. Fortification of Sino-Korean words can be applied variously according to the structure and meaning of the words. Words such as '科', '格', '氣', '法', '病', '症', and '證' are often fortified and at the same time used frequently in Oriental Medicine. Also, many other words are derived from these words. However, there has not been a scholastic consent among the Oriental Medical society as to in which circumstances these words will be fortified. Therefore, a standardization process to stipulate the pronunciation of Oriental Medical terminologies is necessary. 3. Meaningful rendering of Oriental Medical Chinese terminologies into Korean also needs scholastic investigation. Especially, the word 兪 should be meaningfully rendered and pronounced 'su' just like the words 輸 and 腧, but is wrongly pronounced 'yu'. Other than this, the words 井滎兪經合, 秦艽, 膻中, 共振丹, 成無已, and 麗澤通氣湯 should respectively be pronounced 'jeong-hyeong-su-gyeong-hap', 'jin-gyo', 'dan-jung', 'gong-sin-dan', 'Seong-mu-yi', and 'Yi-taek-tong-gi-tang'. Moreover, there are four pronunciations to the word 梴 of 李梴. This should also be standardized. This writer proposes that in the future, correct meaningful rendering of Chinese terminologies into Korean and phonetic signs be inscribed in dictionaries regarding Oriental Medical terminologies.

• 대한한의학원전학회지
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• 제19권3호
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• pp.314-364
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• 2006

This thesis is a study on the Significance of Pulse in Internal Classic(內經脈義) in the Chapters on Vitality of Pulse(脈神章) in the Complete Works of Zhang Jingyue(景岳全書) Vol. IV. The Complete Works of Zhang Jingyue(景岳全書) is composed of 64 volumes. Maishenzhang, the Chapters on Vitality of Pulse(脈神章) is composed of 3 chapters. The first chapter is the Significance of Pulse in Internal Classic(內經服義). The terminology, Maishen(脈神) means the Vitality of Pulse, which was introduced by Zhang Jingyue to emphasize that the keypoint of sphygmological diagnosis is the vitality of pulse. The Significance of Pulse in Internal Classic(內經脈義) is composed of 20 parts including Buwei(部位), Maidu(脈度), Sanbujiuhou(三部九候), Qizhen(七診), Liujingmaoti(六經脈體), ect. in Miraculous Pivot(靈樞). There are no commentaries in most of them, which is because there are explanatory notes in Leijing(類經). Therefore, I referred to explanatory notes in Leijing(類經) to study the Significance of Pulse in Internal Classic(內經脈義), and make a study as followings.

• 대한한의학원전학회지
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• 제25권2호
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• pp.95-105
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• 2012

Objective : This study was conducted to examine the scope and learning objective of Medical classics in the field of the education of Korean Medicine. Method : This study was analyzed and figured out list of classes which was taken by department of medical classics in eleven College of Korean Medicine and one school of Korean Medicine. Results & Conclusions : 1. Now, 14 subjects out of 16 subjects which were taken by whole department of medical classics in Korea can be a proper area of education of medical classics. Now, Hwangjenaekyung and Nangyeong are the only aim of the lessons at the medical classics. Therefore, we present to modify the aims inclusively. 2. The subject of the class have to change as follows. 'Wonjeon' changes into 'Hwangjenaekyung', 'Medical Chinese character' changes into 'Korean medical chinese character', 'medical informatics' changes into 'korean medical informatics'. 3. As we consider the condition that 'Nangyeong' is educating in just four departments of medical classics, we have to discuss about the stature of Nangyeong and to extend education of Nangyeong. 4. In the department of medical classics, we can improve the level of understanding and reading skills by educating the class of 'Sanghanron' and 'Donguibogam'. 5. This study is actively involved in trying to include 'Korean Medical Informatics' and 'Korean medical terminology ' in the education field of the medical classics.

• 대한두경부종양학회지
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• 제13권2호
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• pp.269-274
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• 1997

Parotid canalicular adenoma is a benign neoplasm that is predominantly composed of branching and interconnecting cords of single or double rows of columnar epithelium in a very loose stroma. There has been considerable confusion in the literature concerning the terminology of canalicular adenoma. However, thesedays it has been newly-recognized as a discrete entity of the monomorphic adenoma group. Canalicular adenoma has a remarkable predilection for occurrence in the minor salivary glands such as the upper lip, in contrast with basal cell adenoma that occurs predominantly in major salivary glands such as the parotid gland. We have experienced a case of canalicular adenoma of the parotid gland in a 65-year-old woman. The patient had a palpable mass on the preauricular area for the last 15 years and recently noticed a mild pain and discomfort on the mass. Neck ultrasonography showed a low echogenic mass of 1.0cm in diameter in the right parotid gland and a neck CT scan showed a well-enhanced rectangular-shaped mass. A superficial parotidectomy was performed for the lesion and the final pathologic diagnosis turned out to be 'multifocal canalicular adenoma'.