This study was done to investigate the changes in the quality of life(QOL) of patients who received radiation therapy after surgery for breast cancer. For this purpose, 35 patients were interviewed using a questionnaire. They were followed over 8 month period from the beginning of radiation therapy. Changes in the QOL, side effect of the RT(radiation therapy), depression were measured. The results can be summarized as follows : 1. The mean score of the side effect of RT increased significantly over the period of RT. When the RT was completed, the QOL score was the low-est, and the depression score was the highest, but the changes of these scores were not statistically significant. 2. When the 6-week RT was finished, the QOL was significantly correlated with QOL of the beginning of RT, depression at RT completion and age. At three months after the completion of RT, the QOL was significantly correlated with QOL of the beginning of RT, depression and side effect of RT at three months after the completion of RT. At six months after the completion of RT, the QOL was significantly negatively correlated with age. 3. In the stepwise multiple regression analysis, the major influencing variables on the QOL were various according to the time lapse after the RT. The QOL at the completion of RT was predicted by the QOL at the beginning of RT, depression at the completion of RT and age. The QOL at three months after the completion of RT was predicted by the QOL at the beginning of RT and side effect of RT and depression at three months after the completion of RT. The QOL at six months after the completion of RT was predicted by age. This study suggests that continuous nursing care be required for improving the QOL of breast cancer patients not only during the RT period but also for a long term after the completion of RT.
This study aims to examine primary determinant for medical expenditure depending on different age and income brackets. The age and income brackets are simultaneously taken into account for a forming of structural models, and GARCH methodology is utilized in analyzing the model. Empirical evidence reveals that no matter how general medical care system is appropriately operated, medical expenditure is vulnerable in taking care of potential socially-disadvantaged class and the group of catastrophic medical expenditure as long as the age and income brackets concern, simultaneously. It signifies that more elaborately designed medical-related policy seems to be established to improve its effectiveness. On the contrary, ageing society is comparatively well-treated by public health law and act on long-term care insurance for the aged.
To understand the factors influencing Atrial fibrillation and embolism in mitral valve surgery and prevent their risk, we have reviewed our 324 patients who underwent mitral valve surgery from Fev. 1982 to May 1992. Age, disease duration, lesion type, left ventricular function and left atrial dimension were chosen as preoperative factors influencing the incidence of atrial fibrillation and embolism and their postoperative course, The number and type of replaced valve, site of atriotmy, LA obliteration, ACT and use of Defibrillator were chaser. as operative factors influencing postoperative rhythm change and postop emb-olization. The results of analyses were as follows 1. The incidence of preoperative atrial fibrillation, systemic embolism and LA throbmus was 63. 6%, 10.56% and 19.8% relatively. 2. The preoperative factors of atrial fibrillation onset was old age, prolonged symptom duration, stenotic lesion, lager LAD and lower ejection fraction. In the preoperative systemic embolism preoperative factors were old age, female, stenotic lesion. The left atrial thrombus found more commonly in patients with atrial fibrillation, old age, prolonged symptom duration, stenotic lesion and low ejection fraction. 3. The preoperative atrial fibriation persisted postoperatively in 165[50.9%] and converted to normal sinus rhythm in 50[15.4%]. The preoperative normal sinus rhythm per-eisted in 100[31%] and atrial fibrillation was occured postoperatively in 9[2.7%]. The prolonged symptom duration was the preoperative factor of persist atrial fibrillation. 4. Among 95 long term follow-up patients, atiral fibrillation was continued in 59[60%]. Conversion to normal sinus rhythm was more common significantly in left atriotomy and bileaflet valve replacement. 5. There were 12 patients who had postoperative embolism. Female, persist atrial fibrillation, no LA olbiteration and tilting disc monocusp valve were considered as possible factors influencing postoperative embolism but was impossible to analyse their statistical significance due to small sample size. So we have concluded that the patients with above risk factors need anticoagulant and early surgical intervention. Left atriotomy with minimal atrial injury, left auricular obliteration and bileaflet valve replacement may be needed to reduce postoperative atrial fibrillation persist and embolism.
The purpose of this study was to assess the maternal zinc status during pregnancy and to evaluate the relationship between the zinc concentration of maternal, umblical cord blood and placental tissue and pregnancy outcomes. Venous blood samples were drawn from 53 pregnant women just before delivery and the cord blood of their newborn babies was collected immediately after birth. In addition, placental tissues were extracted. We investigated the difference in the concentration of zinc in maternal, umbilical cord blood and placental tissue in two gestational age groups (preform delivery group [PT] and normal term delivery group [NT]) at 34.7 wk and 39.0 wk of mean gestational age, respectively). We also assessed correlations of the zinc concentration of maternal, umbilical cord blood and placental tissue. Lastly, we studied the correlations between the birth weights and the zinc concentration in the maternal, umbilical cord blood and placental tissue. The concentrations of maternal serum zinc and of umbilical cord serum zinc were significantly higher in the PT group (76.9$\pm$37.4 $\mu/dl$, 101.3$\pm$41.4 $\mu/dl$) than in those of the NT group (57.8$\pm$22.4 $\mu/dl$, 80.7$\pm$27.5 $\mu/dl$), respectively (p<0.05). The zinc concentration of the umbilical cord blood was significantly higher than that of the maternal blood in both groups (p<0.05). There was no significant correlation between the gestational age and the serum zinc concentration in the cord or the maternal serum. Our results showed that there was a negative relationship between the birth weight (r=-0.286) and the maternal serum zinc concentration. Despite there not being a significant difference, there was tendency for the highest concentrations of maternal serum zinc to be associated with the lowest birth weights. These findings support a possible relationship between the maternal zinc status and the pregnancy outcome, and suggest that zinc may play a role in the many biological processes involved in the successful outcome of a pregnancy.
This study was conducted to explore the knowledge of sex, attitude toward sex, sexual satisfaction, the differences of these variables according to the general characteristics, and the correlation of these variables in married women. The data were collected from March 25 to May 20, 2000 by using a mailed questionnaire. The number of subjects were 228 married women in the area of Seoul. Kyunggi-Do and Chungchung-Do. The questionnaire consisted of 67 items including item concerning general characteristics, knowledge of sex, attitude toward sex, and sexual satisfaction. The results were as follows : 1. The mean score and standard deviation of the knowledge of sex was $13.76\pm3.01$ with the range from 5 to 20. The mean score and standard deviation of the attitude toward sex was $57.28\pm9.65$ with the range from 31 to 85 score. The mean score and standard deviation of the sexual satisfaction was $33.15\pm6.54$ with the range from 17 to 48 score 2. The variables influencing on knowledge of sex were children number, women's education level. husband's education level. women's job, economic level. and menstruation status. 3. The variables influencing attitude toward the sex were women's age, husband's age, marriage term, children number, women's religion, economic level. menstruation status, and information acquirement about sex. 4. The variables influencing sexual satisfaction were women's age, husband's age, economic level. menstruation status, and information acquirement about sex. 5. Regarding relationship among the knowledge of sex, the attitude toward sex and the sexual satisfaction, those respondents who had more knowledge of sex had more open attitude toward sex and those respondents who had more open attitude toward sex had higher sexual satisfaction.
This paper investigated how Fine Fly Ash (FFA) with $14,000\;cm^2/g$ of Fineness affects the micro structure and material properties of High-Performance Concrete (HPC) before and after hardening from Material Test of HPC and Cement Paste. FFA is applied as a substitute of Silica Fume which is used necessarily in producing HPC. As a Material Test results, 5% FFA series specimen shows the lower fluidity than SF series specimen. When, however, the Fluidity of 10% FFA series specimen is increased reversely to the similar value of SF series specimen. The Porosity of FFA series specimen of 3 day age is displayed to $21{\sim}24%$, which is higher than $19{\sim}20%$ porosity of SF series specimen, while that of 28 day age is reached to $8{\sim}9%$, which is improved compared with 10% fo SF series specimen. It can be thought that FFA has better influence on the porosity of HPC in case of long term age. The Compressive strength of FFA series specimen shows the similar result with the property of porosity. The compressive strength of 28 day age FFA series specimen is $98{\sim}106%$ of SF series specimen and 107% of plain specimen to reveal better strength development.
Precocious puberty is defined as the appearance of secondary sex characteristics before age 8 years in girls (or menarche before age 9 years) and before 9 years in boys. The age of onset of puberty is progressing to younger age. The pubertal activation of gonadotrophin releasing hormone(GnRH) release requires coordinated changes in excitatory or inhibitory amino acids, growth factors, and a group of transcriptional regulators. A number of factors affecting precocious puberty were explored, including the role of genetic factors, nutrition(body fat) and exposure to endocrine disrupting chemicals. In addition to the psychosocial disturbances associated with precocious puberty, the premature pubertal growth spurt and the accelerated bone maturation result in reduced adult height. Precocious puberty may be gonadotrophin-dependent premature activation of the GnRH pulse generator or gonadotrophin-independent. In rapidly progressing central precocious puberty, GnRH agonists appear to increase final height. However more data on the effect and long-term safety of GnRHa are needed.
This study aims to explore the relationship between onset drinking age and the current Body Mass Index (BMI) level stratified by sex. This study used the data of Korea Community Health Survey (KCHS) 2019, of which 206,987 participants included in study populations for multivariable binomial logistic regression model. The study results show the evidence that the early age of onset alcohol consumption had significantly associated with abnormal BMI status in adult male. These results could be explained by high alcohol consumption and sex difference in social atmosphere which encourages men to drink more. Our findings suggest the need to prevent problem drinking for reducing the long-term side effects of health.
Background: The delayed diagnosis of developmental dysplasia of the hip (DDH) requires complex treatment and sometimes progresses to hip osteoarthritis. Purpose: This study aimed to evaluate the risk factors and screening time for DDH in preterm infants. Methods: A total of 155 preterm infants with a gestational age <32 weeks screened for DDH with ultrasonography were enrolled in this retrospective chart review. Results: The incidence of DDH was 6.45% (10 of 155). Gestational age, birth weight, sex ratio, and breech presentation did not differ significantly between infants treated for DDH (n=10) and nontreated infants (n=145) (gestational age, 29.2±1.4 weeks vs. 29.6±2.0 weeks, P=0.583; birth weight, 1,240±237 g vs. 1,295±335 g, P=0.607; female sex, 7 of 10 (70.0%) vs. 77 of 145 (53.1%), P=0.346; and breech presentation, 5 of 10 (50.0%) vs. 43 of 145 (29.7%), P=0.286, respectively). Performing the first ultrasonography earlier than 38 weeks of postmenstrual age (PMA) increased the risk of an abnormal finding by 3.76 times compared to performing it at ≥38 weeks of PMA. These abnormal findings on ultrasonography resolved spontaneously. Breech presentation increased the risk of minor abnormal findings on the first ultrasonography by 3.11 times versus nonbreech presentation and resolved spontaneously. DDH in preterm infants did not occur predominantly on the left side or in infants born with breech presentation. Conclusion: Performing ultrasonography screening earlier than 38 weeks of PMA caused unnecessary subsequent ultrasonography and overtreatment. Breech presentation was not a risk factor for DDH in preterm infants. However, breech presentation could increase the risk of minor abnormal findings at the 1st ultrasonography compared to nonbreech presentation, which resolved spontaneously. The etiology and risk factors for DDH in preterm infants are somewhat different from those for DDH in term infants.
Objectives We aimed to analyze changes in growth indicators before and after Korean medicine treatment in patients treated at the pediatric department of a hospital. Methods We analyzed the medical records of children and adolescents under 18 years of age who underwent growth assessment between January 1, 2017 and December 31, 2022. Results A total of 21 patients were selected for this study. After treatment, there was a significant increase in the height percentile, whereas bone age-chronological age (BA-CA) and predicted adult height (PAH) did not show significant changes. No major adverse reactions were observed during the treatment. Growth reassessment was conducted twice for 10 participants. When comparing the growth indicators between the assessment sessions, the height percentile showed an increasing trend between the initial and the first growth reassessment. However, there were no significant differences between BA-CA and PAH across the different assessment periods. Conclusions There is a need to establish evidence for the efficacy and safety of continuous Korean medicine growth treatment through the long-term observation of growth indicators in patients undergoing treatment for two or more periods, as well as observational studies on liver and renal function indicators.
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