• Title/Summary/Keyword: temperature limit

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High Intensity Focused Ultrasound for Cancer Treatment: Current Agenda and the Latest Technology Trends (HIFU: 현황 및 기술적 동향)

  • Seo, Jong-Bum
    • The Journal of the Acoustical Society of Korea
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    • v.29 no.2E
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    • pp.55-63
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    • 2010
  • High Intensity Focused Ultrasound (HIFU) is a noninvasive surgical method mainly targeting deeply located cancer tissue. Ultrasound is generated from an extemally located transducer and the beam is focused at the target volume, so that selective damage can be achieved without harm to overlying or surrounding tissues. The mechanism for cell killing can be combination of thermal and cavitational damage. Although cavitation can be an effective means of tissue destruction, the possibility of massive hemorrhage and the unpredictable nature of cavitational events prevent clinical application of cavitation. Hence, thermal damage has been a main focus related to HIFU research. 2D phased array transducer systems allow electronic scanning of focus, multi-foci, and anti-focus with multi-foci, so that HIFU becomes more applicable in clinical use. Currently, lack of noninvasive monitoring means of HIFU is the main factor to limit clinical applications, but development in MRI and Ultrasound Imaging techniques may be able to provide solutions to overcome this problem. With the development of advanced focusing algorithm and monitoring means, complete noninvasive surgery is expected to be implemented in the near future.

Lead(II)-selective Polymeric Electrode Using a Schiff Base Complex of N,N'-Bis-thiophene-2-ylmethylene-ethane-1,2-diamine as an Ion Carrier

  • Jeong, Tae-Jun;Jeong, Dae-Cheol;Lee, Hyo-Kyoung;Jeon, Seung-Won
    • Bulletin of the Korean Chemical Society
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    • v.26 no.8
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    • pp.1219-1224
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    • 2005
  • We prepared lead ion-selective PVC membranes that were based on N,N'-bis-thiophene-2-ylmethylene-ethane-1,2-diamine as a membrane carrier. The membrane electrode has a linear dynamic range between 1.0 ${\times}$ $10^{-5}$ and 1.0 ${\times}$ $10^{-1}$ M with a Nernstian slope of 29.79 mV per decade, and its detection limit was 2.04 ${\times}$ $10^{-6}$ M at room temperature. The potentiometric response is independent of the pH of the solution in the pH range of 5-7. The proposed electrode revealed good selectivity and response for $Pb^{2+}$ over a wide variety of other metal ions in pH 5.0 buffer solutions, and there was good reproducibility of the base line on the subsequent measurements. The membrane electrode has a relatively fast response time, satisfactory reproducibility and a relatively long life time.

Reliability Estimation of Solder Joint by Using Failure Probability Model (파손확률 모델을 이용한 솔더 조인트의 건전성 평가)

  • Myoung, No-Hoon;Lee, Ouk-Sub;Kim, Dong-Hyeok
    • Proceedings of the KSME Conference
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    • 2004.04a
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    • pp.365-370
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    • 2004
  • Generally, component and FR-4 board are connected by solder joint. Because material properties of components and FR-4 board are different, component and FR-4 board show different coefficients of thermal expansion (CTE) and thus strains in component and board are different when they are heated. That is, the differences in CTE of component and FR-4 board cause the dissimilarity in shear strain and solder joint' failure. The first order Taylor series expansion of the limit state function incorporating with Tresca failure criterion is used in order to estimate the failure probability of solder joints under heated condition. Using shear stresses and shear strains appeared on the solder joint, we estimate the failure probability of solder joints with the Tresca failure criterion. The effects of random variables such as CTE, distance of the solder joint from the neutral point(DNP), temperature variation and height of solder on the failure probability of the solder joint are systematically studied by using the failure probability model with first order reliability method(FORM).

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Improved High-Performance Liquid Chromatographic Method for the Determination of N-vanillyl-n-nonivamide(nonivamide) in Korean Hot Peppers (HPLC 법에 의한 국산 고추에 함유되어 있는 Nonivamide의 신규 분석법 개발)

  • Choi, Suk-Hyun
    • Journal of the East Asian Society of Dietary Life
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    • v.16 no.5
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    • pp.585-591
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    • 2006
  • We report a novel HPLC method for analyzing the capsaicinoids and nonivamide. The following conditions were used: a total column and column temperature of $3^{\circ}C$, a detection wavelength of 280 nm, an eluent containing acetonitrile : 0.5% formic acid(31:69, v/v). The experimental data was compared with standard nonivamide and capsaicin. The results showed that nonivamide was eluted in 96.7 minutes with a recovery ratio of 96.5% after adding known nonivamide. In addition, the detection limit for nonivamide was 18.6 ng. The capsaicinoids from Korean pepper were extracted (after blooming 60th) from 3 breeds cultivated in Korea, Buchon, Chungyang and Hanbando. and crisis it analyzed sympathizes the nonivamide in the result nonivamide from the Buchon and the Chungyang which are not detected from the Hanbando $0.16{\sim}0.24{\mu}g/g$ it detects with very small amount it contains it confirmed the each capsaicinoid with the HPLC and the LC-MS. These results are expected contribute to the quality control of various product processes, which includes product delivery inspection as well as examining the capsaicinoids present in the product for possible medicine manufacture and various foodstuff, and the nonivamide content, which may be a feed for various manufacturing processes involving chemical synthesis.

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He-Polymer Microchip Plasma (PMP) System Incorporating a Gas Liquid Separator for the Determination of Chlorine Levels in a Sanitizer Liquid

  • Oh, Joo-Suck;Kim, Y.H.;Lim, H.B.
    • Bulletin of the Korean Chemical Society
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    • v.30 no.3
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    • pp.595-598
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    • 2009
  • The authors describe an analytical method to determine total chlorine in a sanitizer liquid, incorporating a lab-made He-rf-plasma within a PDMS polymer microchip. Helium was used instead of Ar to produce a plasma to achieve efficient Cl excitation. A quartz tube 1 mm i.d. was embedded in the central channel of the polymer microchip to protect it from damage. Rotational temperature of the He-microchip plasma was in the range 1350-3600 K, as estimated from the spectrum of the OH radical. Chlorine was generated in a volatilization reaction vessel containing potassium permanganate in combination of sulfuric acid and then introduced into the polymer microchip plasma (PMP). Atomic emission lines of Cl at 438.2 nm and 837.7 nm were used for analysis; no emission was observed for Ar plasma. The achieved limit of detection was 0.81 ${\mu}g\;mL^{-1}$ (rf powers of 30-70 W), which was sensitive enough to analyze sanitizers that typically contained 100-200 ${\mu}g\;mL^{-1}$ of free chlorine in chlorinated water. This study demonstrates the usefulness of the devised PMP system in the food sciences and related industries.

Simple and Efficient Synthesis of Iron Oxide-Coated Silica Gel Adsorbents for Arsenic Removal: Adsorption Isotherms and Kinetic Study

  • Arifin, Eric;Cha, Jinmyung;Lee, Jin-Kyu
    • Bulletin of the Korean Chemical Society
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    • v.34 no.8
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    • pp.2358-2366
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    • 2013
  • Iron oxide (ferrihydrite, hematite, and magnetite) coated silica gels were prepared using a low-cost, easily-scalable and straightforward method as the adsorbent material for arsenic removal application. Adsorption of the anionic form of arsenic oxyacids, arsenite ($AsO^{2-}$) and arsenate ($AsO{_4}^{3-}$), onto hematite coated silica gel was fitted against non-linear 3-parameter-model Sips isotherm and 2-parameter-model Langmuir and Freundlich isotherm. Adsorption kinetics of arsenic could be well described by pseudo-second-order kinetic model and value of adsorption energy derived from non-linear Dubinin-Radushkevich isotherm suggests chemical adsorption. Although arsenic adsorption process was not affected by the presence of sulfate, chloride, and nitrate anions, as expected, bicarbonate and silicate gave moderate negative effects while the presence of phosphate anions significantly inhibited adsorption process of both arsenite and arsenate. When the actual efficiency to remove arsenic was tested against 1 L of artificial arsenic-contaminated groundwater (0.6 mg/L) in the presence competing anions, the reasonable amount (20 g) of hematite coated silica gel could reduce arsenic concentration to below the WHO permissible safety limit of drinking water of $10{\mu}g/L$ without adjusting pH and temperature, which would be highly advantageous for practical field application.

Comprehensive Empirical Equation for Assessing Atmospheric Corrosion Progression of Steel Considering Environmental Parameters

  • Sil, Arjun;Kumar, Vanapalli Naveen
    • Corrosion Science and Technology
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    • v.19 no.4
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    • pp.174-188
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    • 2020
  • Atmospheric corrosion is a natural surface degradation process of metal due to changes in environmental parameters in the surrounding atmosphere. It is very sensitive to environmental parameters such as temperature, relative humidity, sulphur dioxide, and chloride, making it a major global economic challenge. Existing forecasting empirical corrosion models including the ISO standard are based on statistical analysis of experimental studies without considering the behavior of atmospheric parameters. The present study proposes a reliable global empirical model for estimating short and long-term atmospheric corrosion rates based on environmental parameters and corrosion mechanisms obtained from a parametric study. Repercussion of atmospheric corrosion rate due to individual and combined influences of environmental parameters specifies their importance in the estimation. New global empirical coefficients obtained for environmental parameters are statistically established (R2 =0.998) with 95% confidence limit. They are validated using experimental datasets of existing studies observed at 88 different continental locations. The current proposed model can predict atmospheric corrosion by means of corrosion formation mechanisms influenced by combined effects of environmental parameters, further abating applicability limitations of location and time.

Evaluation Criteria of Reliability on Transmission Control Unit for Passenger Car

  • Choi, M.;Ryu, S.;Lim, J.H.;Jeong, H.S.
    • International Journal of Reliability and Applications
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    • v.11 no.1
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    • pp.55-67
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    • 2010
  • There has been a recent upsurge in demand for the improvement of car reliability in the Northern American which is the primary market of South Korea automobile industry. It has been required that the warranty for transmission control unit for passenger cars directly related to passenger safety or security should be extended for 10 years and 160,000 km. In this paper, the test method for reliability and evaluation criteria is presented to evaluate the reliability on the automatic transmission controller. Reliability certification test can be roughly divided into two types: a quality test and life assessment test and a quality test can be subdivided into a basic performance test and environmental resistance test. There are 3 types of tests on the performance test for automatic transmission controller and environmental resistance test is composed of 14 items. Life test is performed with only the product passed this quality test. In this study, operation limit test at the high-temperatures, accelerated life test under specific temperature and accelerated life test for 2 or 3 stress levels are shown as a way for life test.

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Investigation of Linear Viscoelastic Properties of Xanthan-Carob Mixture in Sol and Gel States

  • Yoon, Won-Byong;Gunasekaran, Sundaram
    • Food Science and Biotechnology
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    • v.18 no.3
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    • pp.618-623
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    • 2009
  • Synergistic interactions between xanthan (X) and carob (C) were investigated by studying the linear viscoelastic behavior of X, C, and X/C mixtures at sol and gel states. At the solution state, storage modulus (G') dominates the linear viscoelastic properties of X/C mixtures. The gelation temperature (52 to $57^{\circ}C$) was weakly dependent on the xanthan fraction (${\phi}x$) in the mixture. The ${\phi}x$ also had a strong effect on G' until ${\phi}x=0.5$. The elastic active network concentration (EANC) of X/C gels was estimated from the pseudo-equilibrium modulus. The EANC for systems with ${\phi}x=0.25$, 0.5, 0.75, and 1 at 1% total concentration was 2.3, 4.4, 4.1, and 0.32 (${\times}10^{-3}\;mol/m^3$), respectively. The maximum synergistic effect was observed at about ${\phi}x=0.5$. The G' at the transition state of X/C mixed gel was proportional to ${\omega}^{3/2}$ at ${\omega}$>${\omega}_{tr}$ (the onset transition frequency) compared to the theoretical limit of ${\omega}^{1/2}$.

Stability limits of premixed microflames at elevated temperatures (고온에서의 예혼합 초소형 화염의 연소안정한계 연구)

  • Kim, Ki-Baek;Lee, Kyoung-Ho;Hong, Young-Taek;Kwon, Oh-Chae
    • Journal of Hydrogen and New Energy
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    • v.17 no.2
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    • pp.158-165
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    • 2006
  • In order to provide the database for designing microcombustors, the combustion characteristics of premixed methane and propane air microflames at normal and elevated temperatures and atmospheric pressure generated on a microtube were studied experimentally and computationally. The stability limits of premixed microflames and the propensity of the microflames near the stability limits were experimentally determined, while the structure of the microflame at the fuel-leanest limit was obtained using a two-dimensional CFD simulation with a reduced kinetic mechanism. For all the microflames, the stability limits were observed only in the fuel-rich region. Results also show substantial extension of stability limits with elevated temperature that is realistic condition for micro fuel processing and significant fuel dilution immediately near the tube exit due to a low Peclet number times Lewis number effect.