• Title/Summary/Keyword: target quality

Search Result 2,200, Processing Time 0.026 seconds

The Role of mRNA Quality Control in the Aging of Caenorhabditis elegans

  • Hyunwoo C. Kwon;Yunkyu Bae;Seung-Jae V. Lee
    • Molecules and Cells
    • /
    • v.46 no.11
    • /
    • pp.664-671
    • /
    • 2023
  • The proper maintenance of mRNA quality that is regulated by diverse surveillance pathways is essential for cellular homeostasis and is highly conserved among eukaryotes. Here, we review findings regarding the role of mRNA quality control in the aging and longevity of Caenorhabditis elegans, an outstanding model for aging research. We discuss the recently discovered functions of the proper regulation of nonsense-mediated mRNA decay, ribosome-associated quality control, and mRNA splicing in the aging of C. elegans. We describe how mRNA quality control contributes to longevity conferred by various regimens, including inhibition of insulin/insulin-like growth factor 1 (IGF-1) signaling, dietary restriction, and reduced mechanistic target of rapamycin signaling. This review provides valuable information regarding the relationship between the mRNA quality control and aging in C. elegans, which may lead to insights into healthy longevity in complex organisms, including humans.

Characteristics of Components in Infant and Children's Clothing Brand (유·아동복 브랜드 구성요소의 특성)

  • Rha, Soo-Im
    • Journal of the Korea Fashion and Costume Design Association
    • /
    • v.13 no.1
    • /
    • pp.135-146
    • /
    • 2011
  • Despite the recession that has affected people's consumption of clothing, the 'Gold Kids' market shows steady growth. This study analyzed the characteristics of components that make up infant and children's wear brands. Firstly, this study found the linguistic features of infant and children's clothing brands. Most brand names have common characteristics such as idiomatic expressions, combination and separation of vocabulary, and more than 6 syllables. Also, when they formative brand quality, they frequently used words like 'girl', 'kid' and 'baby' to clarify the category of the brand product. Also it is meant to present a clear brand concept to the target consumer to offer their brand information and product characteristics. Moreover, English is widely used in the brand names, and they used appropriate symbol graphics that fit the titles and qualities of the brands. Second, to strengthen their brand identity and inherent concepts, infant and children's clothing brands normally use their own particular brand colors wich makes special and strong visual impressions on the target consumer. Also, they mainly use applied sans serif typeface showing the softer brand quality. Brand logos have different visual expressions depending on their brand value and the target consumer. The word type of the logos presents clear brand identity and information to the target consumer. Through the study, we found that infant and children's clothing brands tend to use written brand names for the logo type more than graphic symbol logo patterns. This indicates that infant and children's clothing brands tend to emphasize information transfer rather than visual graphic symbols when they organize brand logos.

  • PDF

Seamless Lawful Interception Handover for 3G IP Multimedia Subsystem (IMS)

  • In, Hoh Peter;Lee, Myoung-Rak;Kim, Do-Hoon;Kim, Nung-Hoe;Yoon, Byung-Sik
    • KSII Transactions on Internet and Information Systems (TIIS)
    • /
    • v.5 no.7
    • /
    • pp.1329-1345
    • /
    • 2011
  • After the 9.11 terror attack, lawful Interception (LI) has emerged as an important tool for anti-terrorist activity. Law enforcement agents and administrative government bodies effectively monitor suspicious target users of permanent IP-based network devices by LI in Packet Data Networks (PDNs). However, it is difficult to perform LI in monitoring migrating users from a location to another, who change their IPs due to the proliferation of portable Internet devices enabling 3G IP Multimedia Subsystems (IMS). The existing, manual handover technique in 3G IMS makes it even more difficult to continue the LI activities due to time-lag reissuance of LI authority warrants when the target users move to a new LI jurisdiction via a roaming service. Our proposed model is a seamless LI handover mechanism in 3G IMS to support mobility detection of the target users. The LI warrants are transferred to the new LI agent automatically with the target users when they move to a new LI jurisdiction. Thus, time-lag human intervention of reissuance of the LI warrants is removed and enables the LI authorities to continue monitoring. In the simulation of our proposed mechanism, the quality of lawful interception achieves a mean score of over 97.5% out of the possible 100% maximum score, whereas the quality of the existing mechanism has a mean score of 22.725%.

Application of Load Duration Curve and Estimation of Delivery Ratio by Flow Durations Using Discharge-Load Rating Curve at Jiseok Stream Watershed (유량-부하량관계식을 이용한 지석천 유역의 부하지속곡선 적용 및 유황별 유달율 산정)

  • Park, Jinhwan;Kim, Kapsoon;Hwang, Kyungsup;Lee, Yongwoon;Lim, Byungjin
    • Journal of Korean Society on Water Environment
    • /
    • v.29 no.4
    • /
    • pp.523-530
    • /
    • 2013
  • This study has been carried out to clarify the characteristics of discharge and pollutant loading according to flow conditions at jiseok stream watershed (JSW). A flow rate and pollutant load in the study watershed were estimated by equation of stage-discharge and discharge-loads rating curve. By using the methods above, I've evaluated the water quality (WQ) of the JSW if it is satisfied with the standard target. I've collected the data of BOD and T-P from the JSW every 8 days for the duration of 12 months. And then, I've schematized the data upon the load duration curve and the results showed me that the WQ of JSW was satisfied with the standard target. I've also collected the same data every each day for the duration of 12 months from JSW and have schematized the data again. And the results showed that it also was satisfied with the standard target. To be concluded, I've determined that point pollution sources of JSW gives more significant impacts to the WQ than non-point pollution sources of JSW and hence, as time goes, point pollution sources will keep depriciating the WQ of JSW. Therefore, further efforts will be required to JSW to maintain the WQ.

An Application of Quantum-inspired Genetic Algorithm for Weapon Target Assignment Problem (양자화 유전자알고리즘을 이용한 무기할당)

  • Kim, Jung Hun;Kim, Kyeongtaek;Choi, Bong-Wan;Suh, Jae Joon
    • Journal of Korean Society of Industrial and Systems Engineering
    • /
    • v.40 no.4
    • /
    • pp.260-267
    • /
    • 2017
  • Quantum-inspired Genetic Algorithm (QGA) is a probabilistic search optimization method combined quantum computation and genetic algorithm. In QGA, the chromosomes are encoded by qubits and are updated by quantum rotation gates, which can achieve a genetic search. Asset-based weapon target assignment (WTA) problem can be described as an optimization problem in which the defenders assign the weapons to hostile targets in order to maximize the value of a group of surviving assets threatened by the targets. It has already been proven that the WTA problem is NP-complete. In this study, we propose a QGA and a hybrid-QGA to solve an asset-based WTA problem. In the proposed QGA, a set of probabilistic superposition of qubits are coded and collapsed into a target number. Q-gate updating strategy is also used for search guidance. The hybrid-QGA is generated by incorporating both the random search capability of QGA and the evolution capability of genetic algorithm (GA). To observe the performance of each algorithm, we construct three synthetic WTA problems and check how each algorithm works on them. Simulation results show that all of the algorithm have good quality of solutions. Since the difference among mean resulting value is within 2%, we run the nonparametric pairwise Wilcoxon rank sum test for testing the equality of the means among the results. The Wilcoxon test reveals that GA has better quality than the others. In contrast, the simulation results indicate that hybrid-QGA and QGA is much faster than GA for the production of the same number of generations.

Evaluation of Resolution of UAV-Image Using Circular Target (Circular target을 이용한 무인항공영상의 해상도 평가)

  • Lee, Jae-One;Sung, Sang-Min
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.20 no.9
    • /
    • pp.474-480
    • /
    • 2019
  • We propose a method to evaluate a Modulation Transfer Function (MTF) using a circular target. In addition, a MATLAB GUI-based resolution analysis tool was developed to enhance the reliability of UAV image quality and the efficiency of the work. For this purpose, images were taken with an FC-6310 during flights at altitudes of 80 m, 120 m, and 150 m and by an iXM-100 at altitudes of 150 m, 200 m, and 400 m. The MTFs of UAV images were compared with traditional photogrammetry by measuring and analyzing MTFs on images taken by the UltraCAM Eagle Mark-2 sensor at a flight altitude of 1000 m. The results show that ${\sigma}MTF$ of the FC-6310 were 0.431(80 m), 0.524(120 m), and 0.699(150 m), and those of the iXM-100 were 0.332(150 m), 0.393(200 m), and 0.631(400 m), respectively. At the altitude of 150 m, the image quality of the iXM-100, which has a high-performance camera, was very high, and the effect of the camera performance on the image quality was confirmed. In addition, the ${\sigma}MTF$ of the UltraCAM Eagle Mark-2 was 0.711 due to the high flight altitude. This was the worst value among all UAV images. However, the ${\sigma}MTF$ of the FC-6310 at 150-m altitude was 0.699, which is almost the same as that of a manned aerial image.

A Study on the Relative Importance of Quality Scorecard(QSC) for Open Quality (오픈퀄리티 품질성과지표(QSC)의 중요도 분석 연구)

  • Song, Ho Jun;Kim, Min Gyu;Shin, Wan Seon
    • Journal of Korean Society for Quality Management
    • /
    • v.49 no.1
    • /
    • pp.61-79
    • /
    • 2021
  • Purpose: The purpose of this study is to study the relative weights of Quality Scorecard (QSC) which was developed for a new quality concept, called Open Quality, in the era of Industry 4.0. Open Quality aims to ensure quality responsibility by accurately measuring the quality level and sharing the quality data with stakeholders. Methods: To analyze the importance of QSC, a survey study was conducted based on 10 types of industry. The relative weights of QSC measures are investigated by both the industry types and the organizational life cycle. Further, the relative importance of QSC was analyzed according to the organization's lifecycle. By dividing the aspects with respect to the result data, application method for QSC is further provided. Results: The result indicates that there are significant differences among Korean companies in terms of the level of Industry revolution stages. Among ten industry types, manufacturing and finance sectors show the highest importance of QSC. QSC measures are also considered more importance in growth stage of the maturity cycle than generator and decline stages. Conclusion: When QSC is adopted for Open Quality, its relative weights must be considered to cope with the unique characteristics of industrial types. Besides, QSC's contribution may vary according to the level of maturity of the target company.

Basic Survey for Establishing Regional Air Quality Standards in Gyeongnam (경남 지역 대기환경기준 설정을 위한 기초조사)

  • Park, Jeong-Ho
    • Journal of Environmental Science International
    • /
    • v.29 no.2
    • /
    • pp.191-200
    • /
    • 2020
  • This study provides a basis for research to establishing air quality standards in Gyeongnam. The trends and deviations in air quality concentrations and short-term environmental standards were analyzed. Furthermore, the regional standards and World Health Organization's (WHO) air quality guidelines (AQGs) were taken into account. The annual average PM10 standard for cities anc counties ate 40 ㎍/㎥ and 30 ㎍/㎥, respectively. SO2 and NO2 are achieving national standards and need to be strengthened to the minimum regional standard and WHO AQGs. The PM2.5 standard, which has not reached national standards, needs to be set at the level of national standards, and is also the target level for 2024 of the Gyeongsangnam and national PM2.5 management plans.

Sound Quality Index Development of Electrically Powered Vehicle Roller Blind (차량용 전동 롤러 블라인드의 음질지수 개발)

  • Sung, Weonchan;Jo, Hyeonho;Kim, Seonghyeon;Park, Dongchul;Kang, Yeonjune
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 2014.10a
    • /
    • pp.785-790
    • /
    • 2014
  • The purpose of this study is to identify the significant sound quality metric and compose the sound quality index of motor driven roller blind which is part of vehicle sunroof. Before subjective evaluation, sound characteristics of roller blind was analyzed and set the target operating sound for subjective evaluation. Thus, transfer sound of roller blind which has the characteristics of sound modulation was used for subjective evaluation. Linear regression was carried out by chosen Zwicker's metrics which are pointed by comments of jurors. Loudness and sharpness related metrics are prime metrics in sound quality index we composed. Effect of roller blind assay when it is attached to real vehicle was identified to evaluate the validity of index.

  • PDF

The Health-related Quality of Life of Obesity (비만과 건강관련 삶의 질)

  • Kwon, Young-Dal
    • Journal of Korean Medicine for Obesity Research
    • /
    • v.4 no.1
    • /
    • pp.125-137
    • /
    • 2004
  • Objective: The purpose of this study is to investigate how to use the Quality of Life(QoL) of obesity and to study the report cases which measure QoL on obesity. Method: This study investigate the definition of Health-related Quality of Life(HRQoL), the measurement of Health-related Quality of Life, and the papers of Health-related Quality of Life on obesity through the books and medicine journals of HRQoL and obesity. Conclusions: 1. The QoL includes role functional ability, the degree and quality of social and community interaction, psychological state, somatic feeling, and life satisfaction than personal health and social well-being. 2. The investigator needs to evaluate the reliability, validity and sensitivity of the scale, and the appropriateness of the instrument for the target population When he decides measurement. 3. The investigator have the well-drilled supporter or himself managed the data and study population to prevent missing data. 4. The investigator should decide which is needed on obesity a obesity-specific or broad-ranging instrument, or both.

  • PDF