• ETRI Journal
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• v.45 no.6
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• pp.939-951
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• 2023

It is critical to estimate the location using only Long-Term Evolution (LTE) and Wi-Fi information gathered by the user's smartphone and deployable for emergency rescue, regardless of whether the Global Positioning System is received. In this research, we used a vehicle to gather LTE and Wi-Fi wireless signals over a large area for an extended period of time. After that, we used the learning technique to create a positioning database that included both collection and noncollection points. We presented a two-step positioning algorithm that utilizes coarse localization to discover a rough location in a wide area rapidly and fine localization to estimate a particular location based on the coarse position. We confirmed our technology utilizing different sorts of devices in four regional types that are generally encountered: dense urban, urban, suburban, and rural. Results presented that our algorithm can satisfactorily achieve the target accuracy necessary in emergency rescue circumstances.

• Journal of Applied Biological Chemistry
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• v.53 no.4
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• pp.189-194
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• 2010

We confirmed the hypo-osmotic shock strengths and duration, different type of vectors, and subcelluar localization to identify the optimum analysis condition of plant aquaporin activity in Xenopus ooctye using Arabidopsis thaliana AtPIP2-1 gene. Six minutes and 1/5ND buffer hypoosmotic shock treatment was the best condition to show the maximum swelling of Xenopus oocytes where AtPIP2-1 was expressed using pcDNA3.1 vector. AtPIP2-1 protein was expressed more efficiently in pGEMHE vector which has 5' and 3' UTR (untranslation region) of Xenopus ${\beta}$-GLOBIN gene in multiple cloning site than in pcDNA3.1 vector. Also green fluorescence of GFP fused to AtPIP2-1 was detected onto oocyte plasmamembrane where is the proper subcellular localization target of AtPIP2-1.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.05a
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• pp.514-515
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• 2021

This paper presents a method to find a target using UAVs in LoRa communication environment. The proposed method proposes a UAV flight path so that the target signal can be found without blind spots. The flight path was changed by using the intensity of the transmitted signal during the flight using the variation of the signal strength. We verified the proposed method by simulation and confirmed that it takes a long time to track the target, although the efficiency of the 3 flights is high. It is best to fly three UAVs to reduce time to find target and increase efficiency when the time is a critical factor. The LoRa communication lowers the production cost and makes it possible to construct the system at low cost.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.6
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• pp.1496-1521
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• 2012

Uncertainty is ubiquitous in target tracking wireless sensor networks due to environmental noise, randomness of target mobility and other factors. Sensing results are always unreliable. This paper considers unreliability as it occurs in wireless sensor networks and its impact on target-tracking accuracy. Firstly, we map intersection pairwise sensors' uncertain boundaries, which divides the monitor area into faces. Each face has a unique signature vector. For each target localization, a sampling vector is built after multiple grouping samplings determine whether the RSS (Received Signal Strength) for a pairwise nodes' is ordinal or flipped. A Fault-Tolerant Target-Tracking (FTTT) strategy is proposed, which transforms the tracking problem into a vector matching process that increases the tracking flexibility and accuracy while reducing the influence of in-the-filed factors. In addition, a heuristic matching algorithm is introduced to reduce the computational complexity. The fault tolerance of FTTT is also discussed. An extension of FTTT is then proposed by quantifying the pairwise uncertainty to further enhance robustness. Results show FTTT is more flexible, more robust and more accurate than parallel approaches.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.24 no.1
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• pp.107-112
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• 2020

Recently, as the field of use of drones is diversified, it is actively used not only for surveying but also for search and rescue work. In these applications it is very important to know the location of the target or the location of the UAV. This paper proposes a target detection method using images taken from drones. The proposed method calculates the latitude and longitude information of the target by finding the location of the target by comparing it with the image to find the image taken by the drone. The exact latitude and longitude information of the target is calculated by calculating the actual distance corresponding to the distance of the image image using the characteristics of the pinhole camera. The proposed method through the actual experiment confirmed that the latitude and longitude of the target was accurately identified.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.49 no.3
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• pp.1-11
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• 2012

Data association plays an important role in intelligent systems. This paper presents the Bayesian formulation of data association and its applications to intelligent systems. We first describe the Bayesian formulation of data association developed for solving multi-target tracking problems in a cluttered environment. Then we review applications of data association in intelligent systems, including surveillance using wireless sensor networks, identity management for air traffic control, camera network localization, and multi-sensor fusion.

• Molecules and Cells
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• v.43 no.3
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• pp.203-214
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• 2020

Post-translational modifications play major roles in the stability, function, and localization of target proteins involved in the nervous system. The ubiquitin-proteasome pathway uses small ubiquitin molecules to degrade neuronal proteins. Deubiquitinating enzymes (DUBs) reverse this degradation and thereby control neuronal cell fate, synaptic plasticity, axonal growth, and proper function of the nervous system. Moreover, mutations or downregulation of certain DUBs have been found in several neurodegenerative diseases, as well as gliomas and neuroblastomas. Based on emerging findings, DUBs represent an important target for therapeutic intervention in various neurological disorders. Here, we summarize advances in our understanding of the roles of DUBs related to neurobiology.

• Progress in Medical Physics
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• v.20 no.4
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• pp.324-330
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• 2009

In this study, we evaluated accuracy and usefulness of CyberKnife Respiratory Tracking System ($Synchrony^{TM}$, Accuray, USA) about a moving during stereotactic radiosurgery. For this study, we used moving phantom that can move the target. We also used Respiratory Tracking System called Synchrony of the Cyberknife in order to track the moving target. For treatment planning of the moving target, we obtained an image using 4D-CT. To measure dose distribution and point dose at the moving target, ion chamber (0.62 cc) and gafchromic EBT film were used. We compared dose distribution (80% isodose line of prescription dose) of static target to that of moving target in order to evaluate the accuracy of Respiratory Tracking System. We also measured the point dose at the target. The mean difference of synchronization for TLS (target localization system) and Synchrony were $11.5{\pm}3.09\;mm$ for desynchronization and $0.14{\pm}0.08\;mm$ for synchronization. The mean difference between static target plan and moving target plan using 4D CT images was $0.18{\pm}0.06\;mm$. And, the accuracy of Respiratory Tracking System was less 1 mm. Estimation of usefulness in Respiratory Tracking System was $17.39{\pm}0.14\;mm$ for inactivity and $1.37{\pm}0.11\;mm$ for activity. The mean difference of absolute dose was $0.68{\pm}0.38%$ in static target and $1.31{\pm}0.81%$ in moving target. As a conclusion, when we treat about the moving target, we consider that it is important to use 4D-CT and the Respiratory Tracking System. In this study, we confirmed the accuracy and usefulness of Respiratory Tracking System in the Cyberknife.

• BMB Reports
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• v.41 no.2
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• pp.170-175
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• 2008

In protein therapy, it is important for exogenous protein to be delivered into the target subcellular localization. To transduce a therapeutic protein into its specific subcellular localization, we synthesized nuclear localization signal (NLS) and membrane translocation sequence signal (MTS) peptides and produced a genetic in-frame SOD fusion protein. The purified SOD fusion proteins were efficiently transduced into mammalian cells with enzymatic activities. Immunofluorescence and Western blot analysis revealed that the SOD fusion proteins successfully transduced into the nucleus and the cytosol in the cells. The viability of cells treated with paraquat was markedly increased by the transduced fusion proteins. Thus, our results suggest that these peptides should be useful for targeting the specific localization of therapeutic proteins in various human diseases.

• Journal of Korean Neurosurgical Society
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• v.38 no.5
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• pp.359-365
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• 2005

Objective : The study investigates the extent of brain shift and its effect on the accuracy of the stereotaxic procedure. Methods : Thirty-five patients underwent 40stereotactic procedures between June 2002 and March 2004. There were 26 males, mean age 59years old. There were 34procedures for Parkinson's disease, 2 for essential tremor, 3 for cerebral palsy, 1 for dystonia. Patients were divided in four groups based on postoperative pneumocephalus : under 5cc [9 procedures], between $5{\sim}10cc$ [13procedures], between $10{\sim}15cc$ [11 procedures] and more than 15cc [7procedures]. The coordinates of the anterior commissure[AC], posterior commissure[PC], and target were defined in pre-and intraoperative magnetic resonance image scans and the amount of air volume was measured with @Target (BrainLab, Heimstetten, Germany]. Results : The mean AC-PC was 26.5mm for patients with less than 5cc, 26.9mm for $5{\sim}10cc$, 25.8mm for $10{\sim}15cc$ and 26.2mm for more than 15cc. The length of AC-PC line and coordinates of AC, PC was also not statistically different, Euclidean distance as well as ${\Delta}x$, ${\Delta}y$, ${\Delta}z$ of AC, PC, and target were also not statistically different among the groups [p>,1]. There was a variance in target of $0.7{\sim}7.6mm$, Euclidean distance of 2.5mm, related to electrophysiology but not to brain-shift. Conclusion : The amount of air accumulated in the intracranial space and compressing the cortical surface has no effect on the localization of subcortical stereotactic target and landmarks.