• Journal of Microbiology and Biotechnology
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• 제21권2호
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• pp.183-186
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• 2011

Biochemical methods were selected to evaluate the role of exopolymeric substances in the stability of biofilms used in bioremediation processes. Biofilms of Thiomonas arsenivorans formed on pozzolana were thus treated with pronase (protein target), lectins (Con A or PNA), calcofluor or periodic acid (polysaccharides target), DNase (DNA target), and lipase (triglycerides target). Neither protease nor DNase treatments had any effect on bacterial adhesion. Lectins and calcofluor treatments mainly affected young biofilms. Lipase treatment had a noticeable effect on biofilm stability whatever the biofilm age. Results suggest that it would be an increased resistance of mature biofilms that protects them from external attacks.

• 영어어문교육
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• 제3호
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• pp.1-12
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• 1997

Errors in EFL writing are very often attributable to learner's inadequate understanding of the target culture. Most of these errors are very hard to identify because they are grammatically correct notwithstanding the meaning. EFL learners almost habitually equate the meaning and usage of a linguistic item when it is present both in the native and the target languages. However, seemingly identical items in both languages sometimes prove themselves to be distinct from each other because of cultural differences. Some expressions in the native language are neither socially acceptable nor meaningful in the target language. Out of sheer ignorance, moreover, one puts a target item in the way he may use it in his native language. For instance. the primary feature of the term "friend" in Korean is [+same age group]. So, a Korean young man is not supposed to call his teacher a friend. This paper aims to clarify patterns of college level writing errors caused by interference of mother culture.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 1998년도 추계학술대회 학술발표 논문집
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• pp.468-473
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• 1998

An intelligent multimode target tracking algorithm using fuzzy logic is presented. Multimode tracking represents a synergistic approach that utilizes a variety of tracking techniques(centroid, correlation, etc.) to overcome the limitations inherent in any single-mode tracker. The design challenge for this type of multimode tracker is the data fusion algorithm. designs for this algorithm are based on heuristic rather than analytical approaches. A correlation-tracking algorithm seeks to align the incoming target image with a reference in age of the target, but has a critical problem, so called drift phenomenon. In this paper we will suggest a robust correlation tracker with gradient preprocessor combined by centroid algorithm to overcome the drift problem.

• 한국항공운항학회지
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• 제27권4호
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• pp.105-113
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• 2019

The commercial pilot retirement age has continued to 65 since the International Civil Aviation Organization(ICAO) amended the recommended age limit from 60. The target of this review is to analyse whether aged pilots have an increased age-dependent risk of medical incapacitation. Medical in-flight incapacitation is actually very rare event and the demonstrated annual incapacitation rate provides an acceptable risk within the criteria known as 1% safety rule for a pilot undertaking air transport operations while some controversies exist. There is a possibility that the accident rate has decreased due to the improved skill by increasing pilot's age. At the decision of flight or not for elderly airline pilot the interacting factors of personal health status, piloting experience and new flight environments should be considered to define job limit criteria than mere the age. Results of a survey led by airline pilot association in Korea shows 65% of airline pilots are willing to fly without any age limit and 87% agreed that age limit is worthy to extend beyond current standard on the basis of medical examinations. Only 11% agreed to maintain current age limit.

• 복식문화연구
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• 제8권4호
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• pp.549-561
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• 2000

The purpose of this study was to survey and analyze the age classification of women customers as a target market and sizes on a label that were actually produced by each brand in Korean national brands ; they were classified into size for bodice and bottom, and compared with the distribution of national data of women's body measurement. They were analyzed and classified by brand groups of 'miss', 'missy', 'Mrs.'and 'madam', The results were ; 1) It was found that recent products for ready-made for women's clothes tend to be designed with target to the measured ages classified by the range of five or ten years. The main practice was that for 'miss'brand group the age range was of five years, and for 'missy'brand group, ten years. And for 'Mrs'and 'madam'brand groups, it was of 15 or 20 years. So that, it is necessary to design their clothes based on their features of body considering the intervals of age. 2) 'Mrs'and 'madam'groups were most remarkable for their distribution into a vast range of sizes for three control dimensions and waist girth size when compared to 'miss'and 'missy'groups. The distribution of brand size had no relation with that of body measurement, and in particular, none was produced for short height size between 145 and 150 ㎝. For tall height size between 175 and 180 ㎝, many brand sizes were distributed while body measurement was few. It means that distribution of brand size was different from real distribution of body measurement was few. It means that distribution of brand size was different from real distribution of body measurement as a result that the larger the bust girth in such cases over 160 ㎝, the larger the size of hip girth. Even as for the height 155 and 160 ㎝ in which body measurement is concentrated, there were many problems because while sizes of 'large'bust girth and 'small'hip girth had a large distribution, their clothes were not produced.

• 한국주거학회논문집
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• 제14권4호
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• pp.49-56
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• 2003

The object of this study is to analyze the influential factors of characteristics of residential locations by age, and to offer a groundwork that can be utilized to direct setting of residential development and housing policies. The main findings are drawn as follows: First, it determines the age groupings which can describe the distribution pattern of residential location, which is broken down into two social subgroups - the older group aged 50 and over, and the younger group, being our educational target. Second, actuality of our education is to influence residential location. Third, four groups that can describe residential location are abstracted. Fourth, the prime of manhood and old age prime of life have been superior within inner zone, while middle age and those who are obliged to support the older group have been superior around the outer zone.

• 대한기계학회논문집A
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• 제41권11호
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• pp.1035-1045
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• 2017

얼굴 모양 및 목소리를 이용하는 방법을 포함하여 연령 및 성별을 분류하는 다양한 방법이 연구되고 있다. 그러나 얼굴 기반 방법은 원거리에서 인식률이 급격히 감소하고, 오디오 기반 방법은 잡음이 많은 환경에서는 적용하기 어렵다. 대조적으로 보행 기반 방법은 대상자가 카메라에 촬영만 되면 인식이 가능하다. 기존 연구에서 카메라의 시점은 측면에서만 볼 수 있어서 실제 환경에서 일반 보행과는 현실적으로 차이가 발생했다. 본 연구에서는 일반 보행 데이터를 이용하여 연령과 성별을 분류할 수 있도록 RGB-D 센서로부터 획득된 골격 모델을 이용한 특징 추출 방법을 제안한다. 실험 결과는 제안된 방법이 실제 환경에서 효율적임을 보여준다.

• Molecules and Cells
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• 제46권11호
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• pp.675-687
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• 2023

Accumulation of pathogenic amyloid-β disrupts the tight junction of retinal pigment epithelium (RPE), one of its senescence-like structural alterations. In the clearance of amyloid-β, the autophagy-lysosome pathway plays the crucial role. In this context, mammalian target of rapamycin (mTOR) inhibits the process of autophagy and lysosomal degradation, acting as a potential therapeutic target for age-associated disorders. However, efficacy of targeting mTOR to treat age-related macular degeneration remains largely elusive. Here, we validated the therapeutic efficacy of the mTOR inhibitors, Torin and PP242, in clearing amyloid-β by inducing the autophagy-lysosome pathway in a mouse model with pathogenic amyloid-β with tight junction disruption of RPE, which is evident in dry age-related macular degeneration. High concentration of amyloid-β oligomers induced autophagy-lysosome pathway impairment accompanied by the accumulation of p62 and decreased lysosomal activity in RPE cells. However, Torin and PP242 treatment restored the lysosomal activity via activation of LAMP2 and facilitated the clearance of amyloid-β in vitro and in vivo. Furthermore, clearance of amyloid-β by Torin and PP242 ameliorated the tight junction disruption of RPE in vivo. Overall, our findings suggest mTOR inhibition as a new therapeutic strategy for the restoration of tight junctions in age-related macular degeneration.

• 한국환경농학회지
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• 제40권3호
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• pp.186-193
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• 2021

BACKGROUND: Before generating transgenic plant using the CRISPR-Cas9 system, the efficiency test of sgRNAs is recommended to reduce the time and effort for plant transformation and regeneration process. The efficiency of the sgRNA can be measured through the transient expression of sgRNA and Cas9 gene in tomato cotyledon; however, we found that the calculated efficiency showed a large variation. It is necessary to increase the precision of the experiment to obtain reliable sgRNA efficiency data from transient expression. METHODS AND RESULTS: The cotyledon of 11^th, 15^th, 19^th, and 23^rd-day-old tomato (Solanum lycopersicum cv. Micro-Tom) were used for expressing CRISPR-Cas9 transiently. The agrobacterium harboring sgRNA for targeting ALS2 gene of tomato was injected through the stomata of leaf adaxial side and the genomic DNA was extracted in 5 days after injection. The target gene edition was identified by amplifying DNA fragment of target region and analyzing with Illumina sequencing method. The target gene editing efficiency was calculated by counting base deletion and insertion events from total target sequence read. CONCLUSION: The CRISPR-Cas9 editing efficiency varied with tomato cotyledon age. The highest efficiency was observed at the 19-day-old cotyledons. Both the median and mean were the highest at this stage and the sample variability was also minimized. We found that the transgene of CRISPR-Cas9 system was strongly correlated with plant leaf development and suggested the optimum cotyledon leaf age for Agrobacterium-mediated transfection in tomato.

• 한국인터넷방송통신학회논문지
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• 제12권3호
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• pp.43-49
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• 2012

모바일 마케팅의 효과를 극대화하기 위해서는 타겟팅을 통한 개인 맞춤형 메시지 전달이 중요하다. 본 논문에서는 타켓 조건에 부합하는 고객을 실시간으로 결정하는 알고리즘을 제시한다. 중간 매개체인 프록시 서버는 데이터 베이스에 고객 프로파일(성별, 연령, 지역 등)과 이를 요약한 정수 값을 저장하고 있다. 기업이 메시지 신디케이션할 경우, 프록시 서버는 부울식으로 표현된 타켓 조건을 정수 값으로 매핑한 후 고객 프로파일 요약 값과 비교함으로써 효율적으로 고객을 결정한다. 따라서 고객이 수백만 명이상인 대규모 시스템에서 "타겟 조건" 검사가 실시간으로 이루어질 수 있고 기존의 데이터 베이스와 쉽게 연동이 가능하기 때문에 효율적으로 개인화된 메시지 전달이 가능하다.