• Title/Summary/Keyword: take-out

Search Result 2,477, Processing Time 0.034 seconds

간암환자의 혈청내 셀레늄 농도에 관한 연구 (The Study on Concentration of Serum Selenium in Patients with Hepatoma)

  • 신원식
    • Journal of Nutrition and Health
    • /
    • 제24권6호
    • /
    • pp.506-515
    • /
    • 1991
  • Serum concentration of selenium were measured ; Studying 36 patients with Hepatoma. 19 with Hepatitis 15 with Liver cirrhosis and 67 Normal control to discover the correlation between serum selenum and cancer. And it have tested also the serum protein and albumin to compare the nutrition status by researching the same persons above The results of those two experiments are as follow : 1) The mean of each group of patients resulting from mearsuing the serum protein content showing 6.91$\pm$0.10g/dl in the patients with hepatoma 7.05$\pm$0.17g/dl in the ones with hepatitis 6.42$\pm$0.13g/dl in the ones with liver cirrhosis and 7.46$\pm$0.06g/dl in the normal control is all being within the normal range such as 6.0-0.8(g/dl) while the distribution is revealin 10.5%, 13.3% in the patients with hepatitis and liver cirrhosis which are below the normal range and 47.2%, 96.9%, 80.0% in the low range of normal one ; therefore in could see that patientsw compared with normal control are in low level in the serum protein content 2) The mean based on the consquence of serum albumin measurement is 3.74$\pm$0.11g/dl. 4.26$\pm$0.13g/dl 4.73$\pm$0.06g/dl in the patients with hepatoma hepatits and normal control which are in between the normal range such as 3.5-5.5(g/dl) except the patients with liver cirrhosis(3/05$\pm$0.12g/dl) while the distribution of the patients with hepatoma an liver cirrhosis is showing 27.8% 73.3% which are below the normal one and 55.5%, 52.6% and 26.7% in the patients with hepatoma hepatits and liver cirrhosis which are in the low area of normal range ; as a result It could find that patients. compared with the normal control are in low level in serum albumin measurement. 3) The mean consulting the serum concentration is 430.86$\pm$26.06$\mu\textrm{g}$/1, 192.37$\pm$18.15$\mu\textrm{g}$/1 186.73$\pm$23.99$\mu\textrm{g}$/1, 196.94$\pm$8.94$\mu\textrm{g}$/1 in the patients with hepatoma hepatitis liver cirrhosis and noramal control ; it shows 2.19 times increasing of serum selenium concentra-tion in the patients with hepatoma 'compared with the normal control and patients with hepatoma spread out at a still higher range in serum selenium concentration test. 4) The serum selenium concentration is not quite dependent on sexes and doesn't show any correlation with age, serum protein, serum albumin. The nutrition status of patients, rested on the results of those experiments, stays in low level, which is caused by that they are in low stage of serum protein and serum albu¬min. In serum selenium concentration, patients with hepatitis and liver cirrhosis, specially, show the condition as good as normal control's; while patients with hepatoma are indicating a significant increasing compared with the three groups, which can be reasoned into that there is a possibility for the patients to take selenium and chemotherapy or radiation treatment, and have high serum selenium concentration by poor excreting of seleno methionine, which is caused by low serum protein content And another thing can be reasoned is that the difference in origination mechanism hetween korean and western people. As a result, It showed that the correlation between serum selenium and seses, age, serum protein, and serum albumin neither exists nor affects on each other.

  • PDF

급성(急性) 기아(饑餓)마우스의 간단백질(肝蛋白質), 핵산(核酸) 및 Guanine Deaminase 활성(活性)에 관(關)한 연구(硏究) (A Study on The Content of Liver Protein, Nucleic Acids, and Guanine Deaminase Activity of Mouse During Acute Starvation)

  • 박승희;김승원
    • Journal of Nutrition and Health
    • /
    • 제1권2호
    • /
    • pp.107-115
    • /
    • 1968
  • Number of aspects, not only nutritional but social as well as political involved in human starvation pose nowadays global problems. In order to help establish the minimum nutritional requirements in the daily life of a man and to free people as well from either undernourishment, malnutrition or even starvation many workers have devoted themselves so far on the research programs to know what and how number of metabolic events take place in animals in vivo. It is the purpose of the present paper to examine in effect to what extent both of the protein and nucleic acids (DNA & RNA) together with an enzyme, guanine deaminase, which converts guanine into xanthine and in turn ends up to uric acid as an end product, undergo changes, quantitatively during acute starvation, using the mouse as an experimental animal. The mouse was strictly inhibited from taking foods except drinking water ad libitum and was sacriflced 24, 48, and 72 hours following starvation thus acutely induced. The animals consisted of two experimental groups, one control and another starvation groups, each being consisted of 6-24 mice of whose body weights ranged in the vicinity of 10 g. The animals were sacriflced by a blow on the head, followed by immediate excision of their livers into ice-cold distilled water, washing adherent blood and other contaminant tissues. The liver was minced foramin, by an all-glass homogenizer immersing it in an ice-bath, followed by subsequent fractionatin of the homogenate (10% W/V in 0.25M sucrose solution made up with 0.05M phosphate buffer of pH 7.4). For the liver protein and guanine deaminase assay, the 10% homogenate was centrifuged at 600 x g for 10 minutes to eliminate the nuclear fraction; and for the estimation of DNA and RNA, the homogenate was prepared by the addition of 10% trichloroacetic acid in order to free the homogenate from the acid-soluble fraction, the remaining residue being delipidate by the addition of alcohol and dried in vacuo for later KOH (IN) hydrolysis. The changes in body and liver wegihts during acute starvation were checked gravimetrically. Protein contents in the liver were monitored by the method of Lowry et al; and guanine deaminase activities were followed by the assay of liberated ammonia from the substrate utilizing the Caraway's colorimetry. The extraction of both DNA and RNA was performed by the Schmidt-Thannhauser's method, which was followed by Marmur's method of purification for DNA and by Chargaff's method of purification for RNA. The determinations of both DNA and RNA were carried out by the diphenylamine reaction for the former and by the orcinol reaction for the latter. The following resume was the results of the present work. 1. It was observed that the body as well as liver weights fall abruptly during starvation, and that the loss of body weight showed no statistical correlation with the decreases in the content of liver protein. 2. The content of liver protein and activity of liver guanine deaminase activity as well decline dramatically, and the specific activities of the enzyme (activity/protein), however, decreased gradually as starvation proceeded. 3. Both of the nucleic acids, DNA and RNA, showed decrements in the liver of mouse during acute starvation; the latter, however, being more striking in the decline as compared to the former. 4. The decreases in the liver protein content as resulted from the acute starvation had no statistically significant correlation with the decrements of DNA in the same tissue, but had regressed with a significant statistical correlation with the fall of RNA in the tissue. 5. The decrease in the activity of guanine deaminase in the liver of mouse during acute starvation was functionally more proportional to the decrease in RNA than DNA, and moreover correlated with the changes in the content of the liver protein. 6. The possible mechanisms involved during in this acute starvation as bring the decreases in the contents of DNA, protein, and guanine deaminase were discussed briefly.

  • PDF

각종 항타공식에 의한 말뚝의 허용지지력 연구 (A Study on the Allowable Bearing Capacity of Pile by Driving Formulas)

  • 이진수;장용채;김용걸
    • 한국항해항만학회지
    • /
    • 제26권1호
    • /
    • pp.106-111
    • /
    • 2002
  • 말뚝에 대한 지지력 평가는 재하시험에 의한 결과를 이용하는 것으로부터 정.동력학적 공식등 다양한 방법들이 사용되고 있다 최근의 국내 조사에 의하면 표준관입시험의 N치에 기초한 Meyerhof공식이 설계단계에서 빈번하게 사용되는 것으로 보인다. 본 연구에서는 국내에서 실시된 다수의 정 동재하시험자료를 가지고 말뚝기초 설계에 사용되는 이론식을 실측값과의 비교를 통해 각종 이론식에 의한 말뚝의 허용지지력 추정의 신뢰성을 알아 보고자 하였다 또한, 경시효과를 고려한 경우 말뚝의 지지력에 미치는 영향에 대해서도 연구가 이루어졌다 본 연구를 통해 얻은 주요 결과로는 Davisson 방법을 기준으로 정도를 평가한 결과, Terzaghi & Peck > Chin > Meyerhof > 수정 Meyerhof 방법순으로 기준값에 근접하였으며 동재하시험결과는 항타공식 중 수정 Engineering News 공식이 가장 실측치에 근접한 결과를 주었으나 이는 해머 효율의 불확실성이라든가 변수의 자체특성, 경시효과등이 고려된 경우에는 다른 결과를 줄 수도 있을 것으로 판단되며, 경시효과를 고려한시험 결과 선단지지력에 비해 주면마찰력이 뚜렷하게 증가하였는데 항타시 대비 주면마찰력은 평균 약 2배정도 증가하였고 Engineering News,수정 Engineering News, Hiley, Danish, Gates, CAPWAP 해석시에 대한 7일의 경시효과를 고려한 관계시은 각각 $Q_{u(Restrike)} / Q_{u(EOID)} = 0.98t_{0.1}$ , $0.98t_{0.1}$, $1.17t_{0.1}$, $0.88t_{0.1}$, $0.89t_{0.1}$, $0.97t_{0.1}$.과 같은 결과를 주었다.

우리나라 연안화물선의 적정선복량 추정에 관한 연구 (A Study on Estimating Optimal Tonnage of Coastal Cargo Vessels in Korea)

  • 이청환;이철영
    • 한국항해학회지
    • /
    • 제13권1호
    • /
    • pp.21-53
    • /
    • 1989
  • In the past twenty years, there has been a rapid increase in the volume of traffic in Korea due to the Korean great growth of the Korean economy. Since transformation provides an infrastructure vital to economic growth, it becomes more and more an integral part of the Korea economy. The importance of coastal shipping stands out in particular, not only because of the expansion limit on the road network, but also because of saturation in the capacity of rail transportation. In spite of this increase and its importance, coastal shipping is falling behind partly because it is givenless emphasis than ocean-going shipping and other inland transportation systems and partly because of overcompetition due to excessive ship tonnage. Therefore, estimating and planning optimum ship tonnage is the first take to develop Korean coastal shipping. This paper aims to estimate the optimum coastal ship tonnage by computer simulation and finally to draw up plans for the ship tonnage balance according to supply and demand. The estimation of the optimum ship tonnage is peformed by the method of Origin -Destimation and time series analysis. The result are as follows : (1) The optimum ship tonnage in 1987 was 358, 680 DWT, which is 54% of the current ship tonnage (481 ships, 662, 664DWT) that is equal to the optimum ship tonnage in 1998. this overcapacity result is in excessive competition and financial difficulties in Korea coastal shipping. (2) The excessive ship tonnage can be broken down into ship types as follows : oil carrier 250, 926 DWT(350%), cement carrier 9, 977 DWT(119%), iron material/machinery carrier 25, 665 DWT(117%), general cargo carrier 17, 416DWT(112%). (3) the current total ship crew of 5, 079 is more than the verified optimally efficient figure of 3, 808 by 1271. (4) From the viewpoint of management strategy, it is necessary that excessive ship tonnage be reduced and uneconomic outdated vessels be broken up. And its found that the diversion into economically efficient fleets is urgently required in order to meet increasing annual rate in the amounts of cargo(23, 877DWT). (5) The plans for the ship tonnage balance according to supply and demand are as follows 1) The establishment of a legislative system for the arrangement of ship tonnage. This would involve; (a) The announcement of an optimum tonnage which guides the licensing of cargo vessels and ship tonnage supply. (b) The establishment of an organization that substantially arrangement tonnage in Korea coastal shipping. 2) The announcement of an optimum ship tonnage both per year and short-term that guides current tonnage supply plans. 3) The settlement of elastic tariffs resulting in the protect6ion of coastal shipping's share from other tonnage supply plans. 4) The settlement of elastic tariffs resulting in the protection of coastal shipping's share from other transportation systems. 4) Restriction of ocean-going vessels from participating in coastal shipping routes. 5) Business rationalization of coastal shipping company which reduces uneconomic outdated vessels and boosts the national economy. If we are to achieve these ends, the followings are prerequisites; I) Because many non-licensed vessels are actually operating and threatening the safe voyage of the others in Korea coastal routes, it is necessary that those ind of vessels be controlled and punished by the authorities. II) The supply of ship tonnage in Korean coastal routes should be predently monitored because most of the coastal vessels are to small to be diverted into ocean-going routes in case of excessive supply. III) Every ship type which is engaged in coastal shipping should be specialized according to the characteristics of its routes as soon possible.

  • PDF

대학교 창업동아리원의 기업가정신이 동아리 효과성에 미치는 영향: 동아리 구성원 다양성의 조절효과를 중심으로 (The Effect of Entrepreneurship of University Start-up Club Members on the Effectiveness of Start-up Club: Focus on the Moderating Effect of Club Members' Diversity)

  • 신정신;이재은
    • 벤처창업연구
    • /
    • 제13권5호
    • /
    • pp.41-54
    • /
    • 2018
  • 최근 사회적으로 청년창업에 대한 관심이 증대되면서, 정부는 다양한 창업지원 정책들을 수립하고 적극적으로 그러한 정책들을 수행하고 있다. 특히, 청년창업을 활성화하기 위한 한 방안으로써 창업동아리의 육성이 제시되고 있으며, 창업동아리의 중요성은 날로 커져가고 있다. 이를 반영하듯, 정부는 대학교의 창업동아리를 지원하기 위한 예산을 매년 늘려가며 창업동아리에게 필요한 자금과 공간을 적극적으로 지원하고 있다. 하지만 안타깝게도 늘어가는 창업동아리의 중요성과 정부의 적극적인 지원에도 불구하고 창업동아리가 얼마나 효과적으로 운영되고 있는지를 살펴보려는 학술적 시도는 아직 충분하지 못한 것이 사실이다. 이러한 이유로 본 연구에서는 대학교 창업동아리원의 기업가정신이 창업동아리의 효과성에 미치는 영향을 분석하고자 한다. 보다 구체적으로 본 연구에서는 선행연구에서 강조하는 바와 같이 창업동아리원의 기업가정신을 위험감수성, 진취성, 혁신성으로 구분하고 이러한 요인들이 창업동아리의 효과성에 미치는 영향을 창업동아리 구성원 다양성의 조절효과를 중심으로 실증 분석한다. 전라남북도 소재 12개 대학교 1112명의 창업동아리 구성원들을 대상으로 실증분석을 실시한 결과는 다음과 같다. 첫째, 창업동아리 구성원의 기업가정신 즉, 위험감수성, 진취성 및 혁신성은 모두 창업동아리의 효과성에 정(+)의 영향을 미치는 것으로 나타났다. 이러한 결과는 많은 선행연구들이 강조하는 것과 일치되는 결과로서 위험을 감수하려는 성향이 높을수록, 어려움을 헤치고 앞으로 나아가려는 성향이 높을수록, 그리고 기존의 틀을 탈피하고 새로운 것을 추구하는 성향이 높을수록 창업동아리의 효과성이 높아진다는 것을 시사한다. 둘째, 창업동아리 구성원 다양성의 조절효과를 검증한 결과 창업동아리 구성원 다양성은 동아리원들의 진취성과 동아리 효과성 간의 관계를 부(-)의 방향으로 조절한다는 증거가 발견되었다. 즉, 창업동아리 구성원의 진취성이 창업동아리의 효과성에 미치는 긍정적인 영향은 다양한 전공의 동아리 구성원을 보유한 동아리의 경우 그러한 긍정적인 경향이 약화된다는 것을 의미한다. 본 연구의 결과는 그동안 상대적으로 많은 관심을 받지 못했던 창업동아리의 효과성의 영향요인들을 규명함으로써, 향후 창업동아리에 관한 후속 연구를 진행함에 있어 의미 있는 이론적 실무적 시사점을 제공할 수 있을 것으로 기대된다.

UAV를 이용한 경관분석 및 활용방안에 관한 기초연구 (Study of the UAV for Application Plans and Landscape Analysis)

  • 김승민
    • 한국전통조경학회지
    • /
    • 제32권3호
    • /
    • pp.213-220
    • /
    • 2014
  • 본 연구는 최근 급속한 기술발전이 이루어지고 있는 (UAV)를 활용하여 지형분석에 적용하기 위한 실험적 연구로 드론과 자동 경로비행에 필요한 시스템을 구축하였다. 구축된 시스템을 이용하여 경로비행의 안정성을 검토하였으며, Waypoint를 이용한 경로비행 촬영을 실시하여 유용성을 검증한 결과는 다음과 같다. 첫째, 9.3ha에 달하는 면적에 대해 경로비행을 실시한 결과 준비시간을 포함하여 실측시간이 총40여분 소요되었으며, 지상부에서 인가한 고도와 속도를 일정하게 유지하는 것을 알 수 있었다. 또한 경로비행 시 지상부에서 설정한 Waypoint 지점에서 정확하게 촬영임무를 수행하여, multicopter를 이용한 사진실측의 효율성을 확인하였다. 둘째, 일반 실측용 무인항공기에 비해 가볍고 저렴한 multicopter와 디지털카메라를 이용하여 촬영의 기동성과 경제성을 확인하였으며, 촬영된 사진데이터의 정합과 DEM, DXF파일의 추출을 통해 수치지형도 보다 정밀한 지형분석이 가능하여 multicopter를 이용한 지형실측의 가능성을 확인하였다. 셋째, 하천내부에 대한 고해상 정사영상사진(20Cm급)을 제작함으로써 하천변일대에 대한 식생과 지형의 변화 등에 대한 분석이 가능한 것을 확인하였다. 또한 촬영지점의 GPS좌표에 대한 데이터베이스를 통해 미세지형의 변화 등과 같은 경관변화와 하천변 일대 또는 수림지 등에 대한 식생변화 등을 지속적으로 모니터링 할 수 있는 기반이 마련 될 수 있을 것으로 판단된다. 넷째, 정사영상분석을 통해 만들어진 DEM은 지형분석 및 가시권 분석 등과 같은 경관분석에서 보다 심도 있는 연구에 활용될 수 있을 것이다. 특히 현재 정부에서 추진 중인 '3차원 국토공간 정보 구축사업'과 연계하여 역사문화자원에 대한 3차원 지형정보 제공 등에도 널리 활용 될 수 있을 것으로 판단된다. 본 연구는 UAV를 이용한 지형분석 및 활용방안에 대한 연구로 도시 및 하천 등 다양한 지형에 대한 분석이 가능할 뿐만 아니라 사적 및 명승 등의 경관관리에 대한 연구와 DSM구축에 따른 가시권 분석 등의 역사문화자원에 대한 관리에도 폭넓게 활용 될 수 있을 것으로 판단된다.

국경을 넘는 해양환경오염에 대한 국가책임과 적용의 한계 -중국의 산샤댐 건설로 인한 동중국해 해양환경 영향을 중심으로- (Limitations of National Responsibility and its Application on Marine Environmental Pollution beyond Borders -Focused on the Effects of China's Three Gorges Dam on the Marine Environment in the East China Sea-)

  • 양희철
    • Ocean and Polar Research
    • /
    • 제37권4호
    • /
    • pp.341-356
    • /
    • 2015
  • A nation has a sovereign right to develop and use its natural resources according to its policies with regard to development and the relevant environment. A nation also has an obligation not to harm other countries or damage environments of neighboring countries as consequences of such actions of developments or use of natural resources. However, international precedents induce a nation to take additional actions not to cause more damages from the specific acts causing environmental damages beyond national borders, when such acts have economic and social importance. That is to say that there is a tendency to resolve such issues in a way to promote the balance between the mutual interests by allowing such actions to continue. A solution to China's Three Gorges Dam dilemma based on a soft law approach is more credible than relying on a good faith approach of national responsibilities and international legal proceedings since the construction and operation of the dam falls within the category of exercising national sovereign rights. If a large scale construction project such as the Three Gorges Dam or operation of a nuclear power plant causes or may cause environmental damage beyond the border of a nation engaged in such an undertaking, countries affected by this undertaking should jointly monitor the environmental effects in a spirit of cooperation rather than trying to stop the construction and should seek cooperative solutions of mutual understanding to establish measures to prevent further damages. If China's Three Gorges Dam construction and operation cause or contain the possibility of causing serious damages to marine environment, China cannot set aside its national responsibility to meet international obligations if China is aware of or knows about the damage that has occurred or may occur but fail to prevent, minimize, reverse or eliminate additional chances of such damages, or fails to put in place measures in order to prevent the recurrence of such damages. However, Korea must be able to prove a causal relationship between the relevant actions and resulting damages if it is to raise objections to the construction or request certain damage-prevention actions against crucial adverse effects on the marine environment out of respect for China's right to develop resources and acts of use thereof. Therefore, it is essential to cumulate continuous monitoring and evaluations information pertaining to marine environmental changes and impacts or responses of affected waters as well as acquisition of scientific baseline data with observed changes in such baseline. As China has adopted a somewhat nonchalant attitude toward taking adequate actions to protect against marine pollution risks or adverse effects caused by the construction and operation of China's Three Gorges Dam, there is a need to persuade China to adopt a more active stance and become involved in the monitoring and co-investigation of the Yellow Sea in order to protect the marine environment. Moreover, there is a need to build a regular environmental monitoring system that includes the evaluation of environmental effects beyond borders. The Espoo Convention can serve as a mechanism to ease potential conflicts of national interest in the Northeast Asian waters where political and historical sensitivities are acute. Especially, the recent diplomatic policy advanced by Korea and China can be implemented as an important example of gentle cooperation as the policy tool of choice is based on regional cooperation or cooperation between different regions.

불면환자 175명의 심박변이도, 체성분 분석 및 동반증상의 특징에 관한 연구 (Study on the Characteristics of Heart Rate Variability, Body component analysis and accompanying symptoms in 175 Insomnia Patients)

  • 하지원;김보경
    • 동의신경정신과학회지
    • /
    • 제21권4호
    • /
    • pp.21-39
    • /
    • 2010
  • Objectives : This study was to investigate the characteristics of the heart rate variability(HRV), types of insomnia and accompanying symptoms of 175 insomnia patients. Methods : For this study we carried out HRV, Inbody of 175 patients with insomnia who have come to Dongeui oriental hospital of Dongeui university from the period of Janaury 2008 to September 2010. We studied the association of the insomnia patients' age and gender with HRV, accompanying symptoms and the types of insomnia. The information of the accompanying symptoms and types of insomnia was based on each patients' progress note. Results : l. There was no significant differences in the characteristics of HRV between male and female. 2. The most frequent symptom shown among the insmonia patents' was headache(41.14%). 3. Comparing the symptoms between the gender, female patients had more dry mouth, alternative periodic chill and fever, and hot flush symptoms than the male patients. 4. Comparing the symptoms between the age groups(divided in two), the lower age group (20~59) had more dizziness and constipation symptoms than the higher age group (over 60). 5. Comparing the types of insomma between the age group, the higher age group (over 60) had more termination insomnia. 6. The types of insomnia of the entire insomnia patients were onset insomnia (73.1%), maintenance insomnia(20.6%), termination insomma(l7.1 %), shallow sleep (52.6%), listed by order of frequency. 7. The patients who takes hypnotics had more anorexia symptoms than the patients who doesn't take hypnotics. 8. There was no visible differences of the average fractal portrait between male and female. The age group of 20~30yrs. had the highest average fractal portrait, and the age group of 30~59yrs. the second highest, and the age group over 60yrs. the lowest. 9. The average of the regulation reserves of the autonomic nervous system(B2) - was lower than the regulation level of the ANS at the present (Bl). 10. When compared the priority of the function of the ANS, it showed that the proportion of HF($38.61{\pm}29.19%$)was the most, and than VLF($30.65{\pm}23.36%$), LF($20.04{\pm}19.13%$) the least. 11. The average of the compensation level of the central nervous system at present(Cl) - was lower than the compensation reserves of the CNS(C2). 12. The average of the control reserves of the cerebrum(D2) - was lower than the control level of the cerebrum at the present (Dl). 13. There was no visible differences between different sexes and ages in pulse rate. 14. The abdomen fat ratio above the line of the insomnia patients was 77.97% in male and 93.1% in female. Both sexes showed that insomnia patients had more abdomen fat that the standard, and female patients had more abd. fat than male patients. Conclusions : This study shows that the HRV of insomnia patients had no significant differences between gender. Fractal portrait, HF, LF and VLF of the insomnia patients are in inverse proportion to the age. The study of the Body Component Analysis showed that female had more abdomen fat than male, and both gender showed more abdomen fat than the standard. When looked into the accompanying symptoms of the insomnia patients, the symptoms show differences according to gender, age and hypnotics taking, as shown as below. In the entire patients, Headache was the most accompanying symptom. Female had more dry mouth, alternative periodic chill and fever, and hot flush symptoms than male. Higher age groups had more dizziness and constipation as accompanying symptoms than lower age groups. Patients who takes hypnotics had more anorexia than those who dont.

Study on the Acceptability and Effectiveness of an Oral Contraceptive Among Iud Drop-outs in Rural Korea

  • Yang, J.M.;Bang, S.;Song, S.W.;Youn, B.B.
    • Journal of Preventive Medicine and Public Health
    • /
    • 제1권1호
    • /
    • pp.51-66
    • /
    • 1968
  • During a period of about one year(November '66 to December '67), the Yonsei University College of Medicine conducted a field trial of the oral contraceptive(Ovulen) in order to study its acceptability and use-effectiveness among IUD drop-outs in Koyang county. We can summarize the outstanding findings from this investigation as follows; 1. 61.4% of the IUD drop-outs interviewed (911 women) wanted to use the pill. Most of the reasons for not wanting to use it(352 women) pertained to either use of other contraceptive methods(98) or subfecundity(150) following IUD terminations. Only 83 out of 911 women gave reasons related to the difficulty of obtaining pills. Therefore, we can state that most IUD drop-outs if still in need of a contraceptive methods are in favor of trying the pill, and especially so if this method is conveniently available. 2. The 467 women or 37% of those who terminated IUD use actually visited the clinic for medical screening, and only 11 of them or 2.4% were rejected because of pregnancy and other medical reasons such as cervical erosion, myoma, breast mass, etc. 5.5% or 25 of the 456 women who received the first cycle did not take a single pill during the study period. 3. When we defined those 431 women who accepted and took one or more tablets we found that women over age 30, with 4 or more children, and/or with a higher educational level were the best prospects for recruitment. 4. In accuracy of use, about two thirds of the users started taking the pill on the 5 th day as directed for the first three cycles, but the percentages rose sharply to about 80% in later cycles. Tardiness in starting pill use in the first cycle may have occurred partly because they had to return to the clinic monthly to get each new cycle. Among acceptors who did not quit between cycles, 80 to 90% were regular users, missing two or less tablets in each cycle. 5) More than 60% of the users felt well and sometimes lost their pre-acceptance symptoms. especially dysmenorrhea. However, 27.4% (58 women) had side effects attributable to the pill compund as nausea, vomiting, indigestion, breast tenderness, decreased lactation or breakthrough bleeding. 25.0% (53 women) also complained of medical diseases or symptoms not related to the pill, especially during the first three cycles. However, as the confidence and experience of the client and the field workers grew, the incidence of unrelated medical complaints quickly fell to a lower level in the later cycles. 6. As of the end of this study, on December 31, 1967, 49.2% (212 women) had discontinued the use of the pill for medical reasons as well as for the non medical reasons. Only one case terminated use due to a pregnancy after taking pills. The cumulative continuation rates (by the life table method), were 58.9%, 51.9%, 41.0% at the end of 3 months, 6 months and one year, respectively. These rates are lower than in the U.S. studies. Even when we add the retaking group to the first segment, the continuation rate goes up only about 5% above the first segment rates mentioned above. Possible explanations are different dosages, the newerness of the method and the use of only one point for pill distribution in the country together with a monthly return for cycle 1, 2, 3, and 4-6.

  • PDF

인지된 위험의 유형이 소비자 신뢰 및 온라인 구매의도에 미치는 영향 (The Impact of Perceived Risks Upon Consumer Trust and Purchase Intentions)

  • 홍일유;김우성;임병하
    • Asia pacific journal of information systems
    • /
    • 제21권4호
    • /
    • pp.1-25
    • /
    • 2011
  • Internet-based commerce has undergone an explosive growth over the past decade as consumers today find it more economical as well as more convenient to shop online. Nevertheless, the shift in the common mode of shopping from offline to online commerce has caused consumers to have worries over such issues as private information leakage, online fraud, discrepancy in product quality and grade, unsuccessful delivery, and so forth, Numerous studies have been undertaken to examine the role of perceived risk as a chief barrier to online purchases and to understand the theoretical relationships among perceived risk, trust and purchase intentions, However, most studies focus on empirically investigating the effects of trust on perceived risk, with little attention devoted to the effects of perceived risk on trust, While the influence trust has on perceived risk is worth studying, the influence in the opposite direction is equally important, enabling insights into the potential of perceived risk as a prohibitor of trust, According to Pavlou (2003), the primary source of the perceived risk is either the technological uncertainty of the Internet environment or the behavioral uncertainty of the transaction partner. Due to such types of uncertainty, an increase in the worries over the perceived risk may negatively affect trust, For example, if a consumer who sends sensitive transaction data over Internet is concerned that his or her private information may leak out because of the lack of security, trust may decrease (Olivero and Lunt, 2004), By the same token, if the consumer feels that the online merchant has the potential to profit by behaving in an opportunistic manner taking advantage of the remote, impersonal nature of online commerce, then it is unlikely that the merchant will be trusted, That is, the more the probable danger is likely to occur, the less trust and the greater need to control the transaction (Olivero and Lunt, 2004), In summary, a review of the related studies indicates that while some researchers looked at the influence of overall perceived risk on trust level, not much attention has been given to the effects of different types of perceived risk, In this context the present research aims at addressing the need to study how trust is affected by different types of perceived risk, We classified perceived risk into six different types based on the literature, and empirically analyzed the impact of each type of perceived risk upon consumer trust in an online merchant and further its impact upon purchase intentions. To meet our research objectives, we developed a conceptual model depicting the nomological structure of the relationships among our research variables, and also formulated a total of seven hypotheses. The model and hypotheses were tested using an empirical analysis based on a questionnaire survey of 206 college students. The reliability was evaluated via Cronbach's alphas, the minimum of which was found to be 0.73, and therefore the questionnaire items are all deemed reliable. In addition, the results of confirmatory factor analysis (CFA) designed to check the validity of the measurement model indicate that the convergent, discriminate, and nomological validities of the model are all acceptable. The structural equation modeling analysis to test the hypotheses yielded the following results. Of the first six hypotheses (H1-1 through H1-6) designed to examine the relationships between each risk type and trust, three hypotheses including H1-1 (performance risk ${\rightarrow}$ trust), H1-2 (psychological risk ${\rightarrow}$ trust) and H1-5 (online payment risk ${\rightarrow}$ trust) were supported with path coefficients of -0.30, -0.27 and -0.16 respectively. Finally, H2 (trust ${\rightarrow}$ purchase intentions) was supported with relatively high path coefficients of 0.73. Results of the empirical study offer the following findings and implications. First. it was found that it was performance risk, psychological risk and online payment risk that have a statistically significant influence upon consumer trust in an online merchant. It implies that a consumer may find an online merchant untrustworthy if either the product quality or the product grade does not match his or her expectations. For that reason, online merchants including digital storefronts and e-marketplaces are suggested to pursue a strategy focusing on identifying the target customers and offering products that they feel best meet performance and psychological needs of those customers. Thus, they should do their best to make it widely known that their products are of as good quality and grade as those purchased from offline department stores. In addition, it may be inferred that today's online consumers remain concerned about the security of the online commerce environment due to the repeated occurrences of hacking or private information leakage. Online merchants should take steps to remove potential vulnerabilities and provide online notices to emphasize that their website is secure. Second, consumer's overall trust was found to have a statistically significant influence on purchase intentions. This finding, which is consistent with the results of numerous prior studies, suggests that increased sales will become a reality only with enhanced consumer trust.