• 한국정보통신학회논문지
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• 제13권7호
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• pp.1399-1410
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• 2009

통증을 치료하기 위한 방법으로 약물요법, 신경차단법, 외과적 수술 등이 있으며, 대체물리요법으로 침구치료, 초음파, 전기 치료, 자기장 치료 등이 응용되고 있다. 이중 전기치료 요법이 많이 이용되고 있으나, 피부나 피하조직의 임피던스에 큰 영향을 받으며, 주로 경피자극이 주된 방법으로 효과가 매우 확률론적이다. 본 연구에서는 집속형 자기장을 이용하여 경혈이나 치료점에 대한 국소 부위를 비침습적으로 자극 할 수 있는 새로운 시스템을 개발하였다. 수기자극과 유사한 자극을 유도할 수 있는 새로운 자기장 침 전극(자기장 자극의 효율성을 고려하여 새로운 형태)을 설계하였다. 개발된 시스템의 임상적 유효성 및 신뢰성을 평가하기 위하여 수기자극과 자기장 자극에 대한 경락전위변화를 측정하여 비교하였다. 실험 결과 자기장 자극 시 수기자극을 할 때 나타나는 충전 방전 형태의 전위변화와 유사한 경락전위변화가 측정되었으며, 자극방식, 세기, 빈도를 조절함에 따라 다양한 반응특성이 나타남을 확인하였다. 또한, 전자기장 자극에 의해 경락전위변화를 유도할 수 있어 이를 이용한 새로운 경혈자극 및 통증치료기로써의 가능성을 확인하였다.

• Molecules and Cells
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• 제23권3호
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• pp.323-330
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• 2007

The mature wheat embryo is arguably one of the best explants for genetic transformation because of its unlimited availability and lack of growth season restriction. However, an efficient regeneration system using mature wheat embryos (Triticum aestivum L.) is still not available. To identify genes related to the tissue culture response (TCR) of wheat, QTLs for callus induction from mature embryos and callus regeneration were mapped using an RIL population derived from the cross of 'Wangshuibai' with 'Nanda2419', which has a good TCR. By whole genome scanning we identified five, four and four chromosome regions conditioning, respectively, percent embryos forming a callus (PEFC), percent calli regenerating plantlets (PCRP), and number of plantlets per regenerating callus (NPRC). The major QTLs QPefc.nau-2A and QPcrp.nau-2A were mapped to the long arm of chromosome 2A, explaining up to 22.8% and 17.6% of the respective phenotypic variance. Moreover, two major QTLs for NPRC were detected on chromosomes 2D and 5D; these together explained 51.6% of the phenotypic variance. We found that chromosomes 2A, 2D, 5A, 5B and 5D were associated via different intervals with at least two of the three TCR indexes used. Based on this study and other reports, the TCRs of different explant types of wheat may be under the control of shared or tightly linked genes, while different genes or gene combinations may govern the stages from callus induction to plantlet regeneration. The importance of group 2 and 5 chromosomes in controlling the TCRs of Triticeae crops and the likely conservation of the corresponding genes in cereals are discussed.

• Molecules and Cells
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• 제38권1호
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• pp.40-50
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• 2015

In the interaction between plants and pathogens, carbon (C) resources provide energy and C skeletons to maintain, among many functions, the plant immune system. However, variations in C availability on pathogen associated molecular pattern (PAMP) triggered immunity (PTI) have not been systematically examined. Here, three types of starch mutants with enhanced susceptibility to Pseudomonas syringae pv. tomato DC3000 hrcC were examined for PTI. In a dark period-dependent manner, the mutants showed compromised induction of a PTI marker, and callose accumulation in response to the bacterial PAMP flagellin, flg22. In combination with weakened PTI responses in wild type by inhibition of the TCA cycle, the experiments determined the necessity of C-derived energy in establishing PTI. Global gene expression analyses identified flg22 responsive genes displaying C supply-dependent patterns. Nutrient recycling-related genes were regulated similarly by C-limitation and flg22, indicating re-arrangements of expression programs to redirect resources that establish or strengthen PTI. Ethylene and NAC transcription factors appear to play roles in these processes. Under C-limitation, PTI appears compromised based on suppression of genes required for continued biosynthetic capacity and defenses through flg22. Our results provide a foundation for the intuitive perception of the interplay between plant nutrition status and pathogen defense.

• 유통과학연구
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• 제13권1호
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• pp.27-33
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• 2015

Purpose - The ICT market in the EU is lagging behind that of the US; however, algorithm and software development within the EU have grown steadily, and they involve focusing on the creative cultural convergence conceptualized as part of Horizon 2020 and connecting neighboring markets in the EE and the Mediterranean region. It is essential to study the requirements to market the EU's creative ICT development in emerging industrial countries after examining its applicability in these countries. Research design, data, and methodology - This study deals with data pertaining to the EU's creative industry and competitive edge. The global cultural expansion of the EU facilitates a new concept involving not only low-cost IT products to enhance local cultural artifacts through R&D and the construction of efficient infrastructure services, but also information exchange with a realistic commercialization of the technology that can be applied for creative cultural localization. In the European industry, research on algorithms has been applied for the benefit of consumers. We investigated how the process is conducted in the EU. Results - Europe needs to adjust its economic structure to the local culture as part of IT distribution convergence. The convergence has been converted into a production algorithm with IT in the form of low-cost production. This is because there is an attempt to improve the quality of transport infrastructure, workforce availability, and the distribution of the distance to the local industries and consumers, using IT algorithms. Integrated into the manufacturing industry, based on the ICT infrastructure and solutions, smart localized regional clusters are formed with the help of grafting. Europe has own strategy to increase the number of hub-and-spoke cities. Europe is now becoming integrated, with an EPC system for regional cooperation rather than national competition in ICT technology. Europe has also been recognized in this study as changing the step-by-step paradigm for global competitiveness through new creative culture industries. Conclusions - As a result, there are several ways of converging with others through EU R&D intensity; therefore, the EU can be seen as successfully increasing marginal value, which is useful in developing a special industrial cluster or local cultural cities that create converged development by connecting people and objects with IT. In fact, when compared to the US, Europe has a strong culture and the car industries have a tendency to overshadow the IT industries with integration of services in IT distribution. Considering the rapid environmental changes, the convergence of IT services is likely to take place in Europe, similar to the pharmaceutical industry and the automotive industry. This requires a focus on human resources and automated systems management. The trend is to move away from low-wage industries, switched to key personnel centers of the local university-industry. EU emphasizes the creation of IT market demand in Europe involving local cultural convergence for marketing as the second step to strengthen the economic hub-and-spoke areas.

• 정보처리학회논문지A
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• 제15A권6호
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• pp.309-316
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• 2008

대공방어용 임무지향 교전통제 컴퓨터는 장시간 동안 임무의 중단없이 방어 임무를 수행하여야 하며, 복잡한 내장형 임무 소프트웨어를 탑재하는 컴퓨터에는 대공방어 임무의 특성상 확실성과 안정성 및 신뢰성을 보장하여야 한다. 구현된 임무지향 교전통제 컴퓨터에서 임무수행의 확실성과 안정성은 4 장의 프로세서로 구성되는 분산 컴퓨터 아키텍처에 의해 보장되며, 신뢰도는 분산 구조의 컴퓨터에 저비용의 능동 예비 이중화(ASR) 고장감내 기법을 적용하여 보장되도록 하였다. 소프트웨어적인 능동 예비 이중화 고장감내 기법은 높은 신뢰도와 신속한 고장복구 성능을 가지는 교전통제 컴퓨터를 저비용으로 구현하므로 대공방어용 컴퓨터에 매우 적합한 기법이다. 본 논문은 능동 예비 이중화 고장감내 기법의 메커니즘과 성능분석에 대해 기술하고, 교전통제 컴퓨터에 ASR 기법과 하드웨어적인 DMR 및 TMR 고장감내 기법을 적용한 경우의 MTBF, 신뢰도, 가용성 및 저비용성을 비교분석하였다. ASR 기법은 72 시간의 임무 시간에 대하여 TMR과 유사한 임무 신뢰도를 제공하며, 저비용의 구현이 가능하므로 교전통제 임무지향 컴퓨터의 고장감내 기법으로 최적인 것으로 분석되었다.

• 한국항만경제학회지
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• 제25권3호
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• pp.183-206
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• 2009

우리나라 교역 대상국 중에서 중국의 비중이 점차로 증가하여 이제는 중국이 우리나라의 제1 투자국이자 최대의 교역 상대국으로 부상하였으며, 이러한 중국과의 무역의존도 증가는 우리나라 해운 물류의 구조에도 변화를 초래하고 있다. 북중국과 인접한 인천항은 중국의 경제성장, 한중간의 교역 증대, 기업의 한중간의 공급사슬 구축으로 인해 경쟁력 제고의 기회를 맞고 있다. 또한 중국의 물량이 크게 증대하고, 중국항만이 대대적으로 개발되고, 중국항만에의 대형선박의 직기항이 증대되면서 동북아 해운항로가 급속히 재편되고 있다. 본 연구는 항만 선택 요인 및 만족도를 one sample T-test, 요인분석, 회귀분석, IPA 방법을 통하여 수도권이라는 광활한 배후시장을 가지고 있으면서 상대적으로 주목을 받지 못했던 인천항에 대하여 항만이 안고 있는 문제점 및 경쟁력 제고 방안을 제시하였다. 본 연구는 항만 선택 요인을 24개 요인으로 선정하여 항만 선택 요인, 만족도, 항로 적합성 조사를 7점 리커트 척도로 측정하였다. 또 항만의 선택 요인 항목에 대해 요인 분석을 실시하여 5개 항목으로 분류하여 각 요인별로 전체만족도에 미치는 영향을 회귀분석을 통해 실시하였다. 인천항의 개선방안의 우선순위를 IPA분석방법 결과 항만접근성, 항비, 선석가용성, 무료장치 기간 및 비용, 하역비 수준, 기타 화물비용, 접안수심 등의 측면에서는 항만 선택 요인은 매우 중요하나 만족도가 낮기 때문에 인천항의 경쟁력 제고를 위해서는 우선적으로 자원을 투여해서 중점적으로 개선해 나가야한다. 인천항의 경쟁력 제고 방안으로서 북미 및 유럽 화물 유치, 선박대형화에 따른 항만시설 인프라 구축, 전용터미널 제공 및 GTO 유치, 항만 배후단지 구축, 물류업체 유치 및 통합네트워크 구축 및 항만 간 협력 강화 등을 제시하였다.

• 아시안잔디학회지
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• 제23권2호
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• pp.353-360
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• 2009

인산은 식물세포막의 형성과 관련 있는 인지질의 주요 구성요소이다. 인산은 토양에서 움직일 수 없기 때문에 자주식물 생장에 저해요인으로 작용하기도 한다. 인산의 이동성과 식물의 이용성은 인산의 시용빈도, 토양에서의 위치, 관수량 및 강우와 같은 다양한 요인에 따라 다르게 나타난다. 본 연구에서는 모래시공 골프장에서 인산의 시용량(0, 146, 293 $kg{\cdot}ha^{-1}$)이 인산을 혼합하는 깊이(0, 7.6, 15.2, 22.9 cm)에 따라 캔터키블루그래스의 생장과 정착에 미치는 영향을 평가하였다. 그 결과 인산은 토양표면과 7.6cm의 깊이에 시용하였을 때 통계적인 유의성이 발견되지 않았다. 하지만 헥타아르당 146과 293kg을 시용하였을 때 무처리보다 식물 체조직 내에서 8~10%와 16~20%의 인산이 검출되었다.

• 한국토양비료학회지
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• 제48권5호
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• pp.404-412
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• 2015

The slurry composting and bio-filtration (SCB) liquid manure has some obvious advantages including a good source of N, P and K, local availability, effective microorganism and the ability to improve soil properties. This study was conducted to evaluate the influence on the changes of soil chemical properties and yield of red pepper by fertigation cultivation with SCB application for 2 years. Red pepper was transplanted in early May in 2013 and 2014. The treatment with three replication was composed of 4 types as control (N 1.0), SCB 0.5N, SCB 1.0N, and SCB 2.0N standards of recommended nitrogen fertilizer ($19kg\;N\;10a^{-1}$). The fertigation cultivation which was installed the surface drip irrigation system was splitted 10 times as $2.5Mg\;10a^{-1}$ nutritional solution included with chemical fertilizer and SCB every 10 days during the cultivation. The height and width of pepper plant were 7.0% and 5.8% higher in SCB 2.0N treatment than that in control. The yield of red pepper increased with the increasing of SCB application rates from SCB 0.5N to 2.0N. The yield of SCB 1.0N was much better 10% in average than that of control, and there was significant differences among all treatments. pH of control soil after final harvest decreased to 6.1, however pH of SCB treated soils increased from 6.7 to 7.1 depending on SCB application rates. The Exch.-K contents of SCB treated soils were increased 13.7 to 56.9% after final harvest compared with control by $0.51cmol_c\;kg^{-1}$. Accordingly, these results showed that SCB 1.0N application rate as a recommended nitrogen level based on soil testing can be used as an alternative nitrogen management as well as plant nutrition for red pepper cultivation.

• 한국식품영양학회지
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• 제34권5호
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• pp.487-497
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• 2021

To investigate the industrial availability of liquid fermentation (PL-ferment) by Phellinus linteus mycelium as a postbiotics for the inhibition of inflammation, PL-ferment was fractionated into culture supernatant (CS), hot-water extract (HW) from PL-ferment, EtOH-precipitate (CP) fractionated from HW, and the dialysate (DCP) of CP. Compared to the other fractions, DCP which is expected to contain exopolysaccharide (EPS) as the major component, significantly decreased the production of NO, IL-6, and MCP-1 in LPS-induced RAW 264.7 cells, and IL-6 and IL-8 in TNF-α and IFN-γ-induced HaCaT cells. The general component analysis results showed that no significant difference in components was observed between the fractions, whereas sugar composition analysis revealed that DCP had decreased glucose and increased mannose contents compared to the other fractions. This suggests that mannose played an important role in the anti-inflammatory activity of the active fraction, DCP. Molecular weight distribution analysis revealed that DCP was mainly composed of low-molecular-weight material-removed high-molecular-weight polysaccharides of 18-638 kDa, suggesting that EPS originated from P. linteus EPS. In conclusion, our results suggest that the DCP of P. linteus mycelium fermentation using the anti-inflammatory activity could be used industrially as postbiotic material.

• 한국산업보건학회지
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• 제31권4호
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• pp.317-330
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• 2021

Objectives: By law, companies in Korea must periodically measure workers' exposure to harmful chemicals (the system is called the Work Environment Monitoring Program (WMP)[a]) and report the results to the government. The government also measures exposure to monitor the WMP's reliability (called Reliability Assessment (RA) for WMP[b]). The issue is that measured data from these two sources are so different that the objectivity of WMP needs to be confirmed by comparing the results using the European Centre for Ecotoxicology and Toxicology of Chemicals' Targeted Risk Assessment (ECETOC TRA). Methods: Step 1: Data collection from WMP reports submitted by companies (n=586) and RA for WMP written by the government (n=33). Step 2: Data Standardization by key information included. Step 3: Data conversion to input-variables required to run the ECETOC TRA model, and run the model with specific data (n=514) which meet the predetermined exposure scenario. Step 4: Statistical data analysis by process category (PROC) and ventilation type from each source ([A] and [B]). Step 5: Additional analysis of any unexpected results. Results: The process categories of the production and handling of Dichloromethane were classified into 12 PROCs, and ten of them were selected to run ECETOC TRA. Modeled values tended to be higher than measured values from both sources. For the measured values from WMP, RCR distribution by PROC was narrow (0.197-0.267, 95% CI) and did not have a relationship with ventilation type, which differs from the tendency of the modeling result. Meanwhile, the measured values from RA for WMP were relatively widely distributed (0.301-1.177, 95% CI) by PROC. In particular PROCs (13,19) were high enough to exceed 1. Also, they become low with better ventilation types and appear differently depending on the ventilation type, similar to the model result. Conclusions: This study revealed that ECETOC TRA might have the potential to serve as a screening tool for exposure assessment and to be used as assistive method for WMP to estimate exposure. Further empirical study is required to confirm its availability as a screening tool.