• Journal of Korean Medical Science
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• v.33 no.47
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• pp.300.1-300.17
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• 2018

Parkinson's disease (PD) is the second most common neurodegenerative disorder. Although its major manifestation is motor symptoms, resulting from the loss of dopaminergic neurons in the substantia nigra, psychiatric symptoms, such as depression, anxiety, hallucination, delusion, apathy and anhedonia, impulsive and compulsive behaviors, and cognitive dysfunction, may also manifest in most patients with PD. Given that the quality of life - and the need for institutionalization - is so highly dependent on the psychiatric well-being of patients with PD, psychiatric symptoms are of high clinical significance. We reviewed the prevalence, risk factors, pathophysiology, and treatment of psychiatric symptoms to get a better understanding of PD for improved management.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.1
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• pp.31-36
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• 2003

The causes of disease as well as the mechanisms that result in the presenting signs and symptoms of patients are basic elements in oriental medicine. The location of the disease is the region on which the cause and the nature of the disease acts. Syndrome reflects the cause of the disease and the pathological change and the location of the disease. It is customary to classify the location of the disease into two major categories. First is based on the exterior and interior and the second is based on the five internal organs. Exterior syndrome is caused by the invasion of exopathogen in skin and hair, channels and collaterals. Interior syndrome refers to the syndrome located deeply in the interior of the body such as five internal organs. The location of the disease is very important to distinguish different syndromes in the diagnosis and the treatment of a disease.

• Korean Journal of Health Education and Promotion
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• v.32 no.1
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• pp.33-44
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• 2015

Objectives: This study examined the effects of optimism and repressive coping on psychopathological symptoms and health management behavior in college students with chronic physical diseases. Methods: We conducted a survey on optimism, repressive coping, psychopathological symptoms, and health management behavior to patients with a chronic physical disease. Results: The results showed that both of optimism and repressive coping were related to fewer psychopathological symptoms. In addition, the repressive coping were related to fewer risk taking behaviors. Conclusion: Based on the results of this study, it is possible that how to well protect their psychological physical health to patients with a chronic physical disease.

• KIPS Transactions on Software and Data Engineering
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• v.7 no.11
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• pp.443-450
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• 2018

Crohn's disease, which is recently increasing in Korea, may be seen throughout the gastrointestinal tract and cause various symptoms. In particular, Crohn's disease is especially difficult to diagnose with several symptoms similar to other ulcerative colonic diseases. Thus, some studies are underway to distinguish two or more similar diseases. However, the previous studies have not described the procedural diagnosis process of it, which may lead to over-examination in the process. Therefore, we propose a diagnosis process of Crohn's disease based on the analysis of redundancy, sequential linkage and decision point in the diagnosis of Crohn's disease, so that it enables to identify ulcerative colonic diseases with symptoms similar to Crohn's disease. Finally, we can distinguish the colon diseases that have symptoms similar to Crohn's disease and help diagnose Crohn's disease effectively by defining the proposed process-oriented association as an ontology. Applying the proposed ontology to 5 cases showed that more accurate diagnosis was possible and in one case it could be diagnosed even with fewer tests.

• Journal of Sasang Constitutional Medicine
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• v.26 no.3
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• pp.272-280
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• 2014

Objectives This research was carried out to establish the clinical practice guideline(CPG) for Yin-Deficit Diurnal-Heat (Eumheo-oyeol) symptomatology of Soyangin disease. Methods Dongeuisusebowon(sinchuk edition) and several kinds of literatures including journal articles concerning this symptomatology of Soyangin disease were collected and classified. Sasang constitutional specialists' conference was held to make an agreement on the conflicting issues as well. Consensus was drawn as a result of the conference. Results & Conclusions 3 papers were selected as an inclusion and exclusion criteria for the relevant articles to Yin-Deficit Diurnal-Heat (Eumheo-oyeol) symptomatology of Soyangin disease. Yin-Deficit Diurnal-Heat (Eumheo-oyeol) symptomatology consists of two aspects : Yin-Deficit Diurnal-Heat (Eumheo-oyeol) severe pattern and Yin-Deficit Diurnal-Heat (Eumheo-oyeol) critical pattern. In Yin-Deficit Diurnal-Heat (Eumheo-oyeol) severe pattern contains 1 disease, namely, Clear Yang Depletion of Large Intestine (Daejang-cheongyang Moson) pattern (Lower wasting-thirst (Haso) pattern). In Yin-Deficit Diurnal-Heat (Eumheo-oyeol) critical pattern contains 2 diseases, Yin-Deficit Diurnal-Heat (Eumheo-oyeol) pattern and Yin-Deficit Diurnal-Heat (Eumheo-oyeol) advanced pattern. Yin-Deficit Diurnal-Heat (Eumheo-oyeol) symptomatology has several kinds of symptoms like dry mouth, disliking to drink much water, diurnal body fever, coldness on the back and nausea as well as body fever, chest discomfort, constipation or dry stool as a common symptoms of Interior Heat disease. Clear Yang Depletion of Large Intestine (Daejang-cheongyang Moson) pattern (Lower wasting-thirst (Haso) pattern) has above mentioned symptoms and much urine/turbid urine, thin thigh and knee joints and twinge of joint pain over the body. Yin-Deficit Diurnal-Heat (Eumheo-oyeol) pattern has symptoms like indigestion and epigastric discomfort, abdominal pain and vomiting in addition. Yin-Deficit Diurnal-Heat (Eumheo-oyeol) advanced pattern has symptoms like hematemesis as well.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.1
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• pp.19-28
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• 2011

More than 30,000 Wooden Slips were excavated in the Juyan region in 1930s and 1970s. These slips recorded military actions of Juyan Frontier Fortress during Han dynasty, which is about BC 100 ~ AD 30. On the slips, there are many disease names and symptoms mentioned. We focused on a certain disease name, namely, Shnaghan(傷寒; injured by cold), which is the main subject of Shangha-lun(傷寒論). Looking closely into these Juan Wooden Slips, we found many articles recording Shanghan, including related diseases and symptoms, such as Shanghan(傷汗; injured by sweat), headache, fever and chills, immobilization of limbs, unacceptance of foods. And there are another Shanghan-related symptoms, such as inflation of upper-abdomen(心腹支滿), pain of upper abdomen(心腹痛), strain of both armpits(兩胠葥急), inflation of chest(胸脇支滿), tightness and fear in the chest(煩滿). Although they have no direct relationship with Shanghan, there are many symptoms, including the external wounds of waist, finger, thigh, back, breast and head, abscess of leg and elbow, sore throat, itching, leucorrhea, powerlessness of hands and legs(手足癃), visceral injury(傷臟), tinnitus, cold, warm and heat. Because the Wooden Slips are very short, with some characters even missing, we can not confirm the detail of the disease and symptoms. In addition, we will report about the herbal medicines and other treatments, which are recorded on the slips, by further research.

• Journal of Oriental Neuropsychiatry
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• v.17 no.2
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• pp.245-254
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• 2006

Symptoms of Psychosomatic disease are various. Mamok(麻木), one of that symptoms, is a kind of sensory disorder and similar to numbness but more complicated. In this report, we described two men diagnosed as psychosomatic disease and undifferentiated somatoform disorder. One complained Mamok of his tongue and the other complained it of his right arm and leg. And both of their symptoms were disappeared quickly after treated by Hwa-acupuncture.

• Advances in pediatric surgery
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• v.8 no.1
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• pp.48-53
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• 2002

Diagnosing Hirschprungs disease (HD) is a clinical challenge to pediatric surgeons. The cardinal symptoms are failure of passage of meconium within first 24 hours of life, abdominal distension, and vomiting. The severity of these symptoms and the degree of consitpation vary considerably between patients. HD is suspected on the basis of history and clinical findings and the diagnosis is established by radiological examination, anorectal manometry, and histochemical analysis of biopsy specimens. In this review, the advantages and pitfalls of each diagnostic modality are discussed. And a diagnostic approach utilizing these diagnostic modalities in children with suspicious HD is presented.

• Korean Journal of Psychosomatic Medicine
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• v.22 no.2
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• pp.130-137
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• 2014

Objectives : Obsessive-compulsive(OC) symptoms have yet to be directly studied in neurodegenerative conditions involving behavioral changes. To examine regional abnormalities in the brains of dementia patients with OC symptoms, we assessed the gray matter density using voxel-based morphometry(VBM). Methods : We performed brain magnetic resonance imaging(MRI) with VBM analysis in 106 dementia patients with OC behaviors. In this study, OC behaviors were investigated in patients with neurodegenerative disease using the modified Manchester Behavior Questionnaire. Results : The OC behavior scores were correlated with structural brain volume using VBM. The total OC symptom score correlated negatively with the volume of both putamens, the right middle orbitofrontal gyrus, both anterior cingulate cortices, and the left insula(p<0.001, uncorrected). No gray matter reductions were associated specifically with the OC symptom sub-categories. Conclusions : Our results suggest that abnormalities in these brain regions may play an important role in the pathophysiology of OCD in neurodegenerative disease. This is the first lesion study to investigate the neural basis of OCD behaviors in neurodegenerative disease.

• Journal of Sasang Constitutional Medicine
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• v.27 no.2
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• pp.297-306
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• 2015

Objectives This study was designed to report treatment of Soyangin Mangeum with gastroesophageal reflux disease. Methods We treated two patients suffering from dyspepsia and chest discomfort. A female patient was treated with Hyeongbangjiwhang-tang. A male patient was treated with Hyungbangsabaek-san. The progress was evaluated with the visual analogue scale for dyspepsia, chest discomfort, and other symptoms. Results A female patient's symptoms such as dyspepsia, chest discomfort were almost cured. but they increased with patient's emotional state repeatedly. A male patient' symptoms such as abdominal pain, dyspepsia, nausea, heart burn was successfully disappeared. Conclusions Hyeongbangjiwhang-tang and Hyungbangsabaek-san can be considered as a treatment for patient with Soyangin Mangyin diagnosed as gastroesophageal reflux disease.