• 한국약용작물학회지
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• 제21권1호
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• pp.1-6
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• 2013

Buckwheat (Fagopyrum esculentum) has been known for having strong anti-oxidant, anti-mutagenic, and anti-carcinogenic activities. The free radical theory of aging, also known as the oxidative stress theory of aging, claims that cellular oxidative damage accumulated with time is a major causal factor of aging. In the present study, we investigated the effect of buckwheat extracts on resistance to oxidative stress and aging using Caenorhabditis elegans as a model system. Survival under an oxidative-stress condition induced by paraquat increased markedly following 500mg/L buckwheat extracts treatment, suggesting lower cellular oxidative damage by buckwheat extracts. A lifespan assay also revealed that treatment of buckwheat extracts significantly extended both the mean and maximum lifespan in C. elegans. Interestingly, this lifespan-extension by buckwheat extracts was not accompanied by reduced fertility. These findings suggest that buckwheat extracts can confer longevity phenotype to C. elegans through its strong anti-oxidant activity and support the aging theory which emphasizes a pivotal role of oxidative stress during aging.

• 응용통계연구
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• 제27권2호
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• pp.331-343
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• 2014

본 논문에서는 군집 구간중도절단된 자료에서 생존시간이 군집의 크기에 의존할 때 주변모형으로부터 가중 추정 방법과 군집 내 재추출 방법을 써서 모수를 추정하고 그 추정량의 점근적 성질을 살펴보았다. 모의실험을 통해 추정량의 편향의 크기와 신뢰구간의 포함율 측면에서 볼 때 제안한 두 추정 방법이 생존시간과 군집의 크기 간의 종속 관계를 무시한 방법보다 우수한 것으로 나타났다. 제안한 추정 방법을 림프성 사상충 자료에 적용한 결과에 따르면 서로 다른 두 치료방법이 유의하게 다르지 않았으며 나이 효과도 매우 유의하지 않은 것으로 나타났다.

• Journal of Chest Surgery
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• 제32권10호
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• pp.897-902
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• 1999

Use of the left internal thoracic artery(ITA) to bypass the left anterior descending(LAD) coronary artery has become the standard of care based on its superior graft patency, reduced cardiac events, and enhanced survival. But rarely we encountered with injury to the artery during harvesting which leads to loss of the merits of surgery. We reconstructed inadequate ITAa with other arterial conduits so proximal stump to be a blood source if possible. Maternal and method: Between January 1996 and March 1999, 12 patients received bypass with the reconstructed left internal thoracic artery grafts to left anterior descending artery because of an injury(n=8), short or small(n=4). Right or left ITA was used to LAD as a free graft(n=2). And the other 10 left ITAs were extended with radial artery(n=6), right ITA(n=3), saphenous vein(n=1). Composite "T" graft was made with other arterial conduits in these extended graft(n=5). Result: There was only one morbidity of minor would problem, and no mortality. The patency of extended graft to LAD was complete in 5 patients who received angiography during the period of 2wks to 2 years postoperative, but one of side branch of "T" graft occluded. All of these patients were well. Conclusion: Reconstructive extension with the use of other arterial conduit for the injured proximal ITA is warranted in any patients with acceptable results. acceptable results.

• 원예과학기술지
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• 제29권2호
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• pp.156-159
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• 2011

절화용 거베라 'Sunmyo'는 적색의 'Beauty'를 모본, 황색의 중형인 'Tamara'를 부본으로 하여 2001년에 교배하여 선발한 계통으로부터 육성하였다. 2007년부터 3년간 특성검정을 실시하였는데, 'Sunmyo'는 화색이 밝고 선명한 황색의 절화용으로 화형이 안정된 반겹꽃의 중륜화 품종이다. 절화 수량은 본당 70.0본/년으로 대비품종인 '비로'(51.0본/년)에 비해 37.0% 증수 되었으며 절화 수명은 7.5일로 나타났다. 월동 후 생존율은 85.0%이었으며 개화 소요일수는 95일이었다.

• Journal of Chest Surgery
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• 제33권8호
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• pp.688-692
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• 2000

Descending Necrotizing Mediastinitis(DNM) is a complication of oropharyngeal infections that can spread to the mediastinum. It is difficult to diagnose early because clinical and radiologic findings appear in the late stage of the infection. late diagnosis is the principal reason for the high mortality in DNM. An 18-year-old female admitted with Ludwig's angina from dental caries. Despite of combined antibiotics, dental extraction and drainge of submental abscess, infection spread to the cervical area. Chest computed tomogram revealed extension of the abscess to the pretracheal and periaortic space and development of bilateral pleural empyema. We performed bilateral cervical mediastinotomy and thoracotomy for drainage and debridement. Tracheostomy to secure the airway and postoperative pleural irrigation were performed. Postoperative course was uneventful and patient was discharged on the 40th postoperative day. It is important to perform chest CT scanning for early diagnosis of DNM when oropharyngeal infection spreads to the cervical area. Improved survival of patients with DNM implies early and radical surgical drainage and debridement via a cervical mediastinomy and thoracotomy.

• 디지털산업정보학회논문지
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• 제11권4호
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• pp.1-12
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• 2015

This research analyzes the current state of the semiconductor industry delivering the prediction for the future development of the semiconductor industry along with some semiconductor memory's responsive strategies. In the 2014, top 10 semiconductor companies were targeted and studied its growth based on its profitability and growth indications in perspective during three years. The system semiconductor industry with the increase in Hyper-scale customers, proactive actions in the technology consortium, is polarizing caused by increased R&D expense to ensure process scaling limits and high performance, and some results have shown: PC and Mobile slowdown and growth recession phenomenon due to IoT's unclear direction. The leading company is to secure new growth engines through 'Acquiring'. While as the subordinated companies following this consecutive survival through the 'Acquired', the future of system semiconductor industry is to strengthen the market dominance and its techniques by concentrating on the reorganization of the market by few large companies. Accordingly, the semiconductor memory industry is expected to reach the limit of its expansion to domain of system semiconductor, and it is highly suggesting the need of the 'Memory Life Extension' growth strategy.

• 한국응급구조학회지
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• 제24권3호
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• pp.155-160
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• 2020

Torsades de pointes refers to polymorphic ventricular tachycardia (PMVT), which is caused by the suppression of potassium channels owing to genetic and electrolytic abnormalities, resulting in the extension of the QT interval. Symptoms range from spontaneous circulation recovery to fainting and sudden death. Defibrillation, magnesium correction, and the use of lidocaine as an antiarrhythmic agent are recommended as treatments for persistent torsades de pointes. Currently, only amiodarone is available in the ambulance; however, torsades de pointes does not respond efficiently to amiodarone because it suppresses potassium channels and increases the refractory period of the myocardium. Lidocaine, in contrast, reduces the relative refractory period of the myocardium caused by suppressing sodium channels; thus, it inhibits the occurrence of and treats arrhythmia. In cases where PMVT did not respond to defibrillation, the administration of lidocaine showed no difference in survival and discharge rates compared to amiodarone. Thus, ambulances must be equipped with provisions to administer lidocaine.

• Fisheries and Aquatic Sciences
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• 제27권3호
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• pp.195-205
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• 2024

Amphipoda is a benthic fauna occupying aquatic environments that can be used as a live feed for mud crabs. The abundance of amphipods in the water is thought to impact the preying capacity of crablets, which in turn will affect their growth performance. This study aims to determine the preying capacity of the crablet stage of Scylla tranquebarica exposed at different densities (20, 30, and 40 amphipods / 0.5 L) of amphipod, Grandidierella megnae. The preying capacity was estimated by counting the number of amphipods ingested by an individual crablet during the 60-day rearing period. The main parameters measured were daily consumption rate (DCR), Cumulative molting (CM), Feed conversion ratio (FCR), and the specific growth rate of weight (SGR-W). The results showed that the DCR and FCR were not affected by amphipod densities but the higher the amphipod density the higher the SGR-W and CM. Based on this study, 30 amphipods / 0.5 L is recommended as the optimal density to optimize the DCR and improve the growth performance of crablets. It is also proposed that surplus live feed will potentially reduce the cannibalism rate of crablets during weaning. However, more research needs to be carried out to elucidate the benefits of crablet-feeding amphipods in communal systems.

• 한국양식학회지
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• 제9권3호
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• pp.223-232
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• 1996

산지가 다른 3지역의 바지락, Ruditapes philippinarum 종패를 재료로 전남 승주군 해룡면 신성포의 바지락 양식장에서 산지별 및 방양밀도별로 성장과 생존에 관하여 조사하였다. 실험기간 동안의 수온은 4.5 (1월)${\~}26.0^{\circ}C$ (8월) 범위로 나타났으며, 비중은 1.0216 (8월)${\~}1.0248$ (2월) 범위였다. 산지별 바지락의 양성결과, 각장 성장은 하동산이 $2.30{\pm}0.05$ cm에서 $3.29{\pm}0.02$ cm, 울산산이 $1.32{\pm}0.02$ cm에서 $3.15{\pm}0.02$ cm, 고창산이 $1.24{\pm}0.03$ cm에서 $3.18{\pm}0.02$ cm로 성장하여, 고창산의 성장이 하동산과 울산산에 비해 빠르게 나타났다. 밀도별 양성실험에서 개시시 각장 $1.32{\pm}0.02$ cm 내외였던 것이 실험 종료시 $m^2$당 1,000개체 실험구가 $3.21{\pm}0.02$ cm로 2,000개체 실험구 $2.61{\pm}0.02$ cm 보다 성장이 빨랐으며, 전중도 1,000, 1,500 및 2,000 개체구에서 각각 $5.47{\pm}0.22\;g,\;5.12{\pm}0.788\;g,\;4.62{\pm}1.62\;g$로 나타나 밀도가 낮은 실험구에서 성장이 좋았다. 산지별 바지락의 생존율은 실험 종료시 하동산, 울산산, 고창산이 각각 $69.4\%,\;63.8\%,\;41.7\%$로 고창산이 가장 낮았으며, 밀도별 생존율은 1,000개체, 1,500개체, 2,000개체 실험구가 각각 $70.8\%,\;67.8\%,\;59.0\%$로 밀도가 높을 수록 낮아지는 경향을 보였다.

• Radiation Oncology Journal
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• 제17권4호
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• pp.281-286
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• 1999

배경 및 목적 : 고형암의 뇌전이는 20$\~$40$\%$의 암환자에서 발생하고, 뇌전이 후 1년 생존율은 15$\%$정도로 예후가 불량하며 고식적 방사선치료 등에 의하여 70$\~$90$\%$의 환자에서 증상이 호전되나 대부분의 환자가 결국은 뇌전이로 인하여 사망하게 된다. 이에 고형암의 뇌전이로 방사선치료를 받은 환자를 후향적으로 조사하여 임상양상과 생존기간을 분석하고 예후인자를 파악하였다. 방 법 : 대상환자는 1987년 1월부터 1998년 1월까지 이화여자대학교 부속병원에서 고형암의 뇌전이로 고식적 전뇌 방사선치료를 받은 71예이었다 대상 환자의 중앙연령은 63세(24$\~$89세)였고 남자 50예, 여자 21예이었다. 고식적 치료 후 신경증상의 호전정도를 평가하고, 연령, 종양의 원발병소, 진단당시 뇌전이 동반 유무, 타장기 전이 유무, 뇌전이 병변 수, 치료방법에 따라 생존기간을 비교하였다. 결 과 : 뇌전이시 동반된 증상은 두통이 34예로 가장 많았으며 근력 약화 29예, 오심 구토 및 의식 변화 각 14예, 시력장애 8예, 구음장애 7예 순이었고 치료 후 신경증상의 호전은 64.9$\%$에서 관찰되었다. 뇌전이의 치료로 전체환자 중 7예에서는 뇌전이의 수술적 제거 후 전뇌 방사선치료를 받았고 나머지 64예는 전뇌 방사선치료만을 받았다. 전체환자의 중앙생존기간은 16주였고 1년 생존율은 IS.0%, 2년 생존율은 5.1$\%$였다. 타장기 전이가 없이 뇌전이 단독인 군(n=27)의 중앙생존기간은 33주로 타장기 전이가 있는 군의 10주에 비해 길었다(p=0.0018). 뇌전이 수가 단일 병소인 37예의 환자에서는 수술적 제거 후 방사선치료를 한 군(n=7)의 중앙생존기간이 40주로 방사선치료만 시행한 군의 16주에 비해 길었다(p=0.0438). 이 외에 연령, 원발암의 종류, 전신수행 상태, 진단당시 뇌전이 동반 유무, 뇌전이 병변 수에 따른 생존기간의 차이는 없었다. 결 론 : 고형암에서 뇌전이는 나쁜 예후인자이나 뇌로의 단독전이는 타장기 전이 동반에 비해 예후가 양호하므로 수술적 절제, 방사선치료 등의 다양한 방법을 이용한 보다 적극적인 치료로 생존율 및 삶의 질을 향상시킬 수 있을 것이다.