• Title/Summary/Keyword: surface-displayed

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Development of the Phage Displayed Peptide as an Inhibitor of MCP-1 (Monocyte Chemoattractant Protein-1)-mediated Angiogenesis

  • Jeong, Sun-Joo
    • Proceedings of the Microbiological Society of Korea Conference
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    • 2005.05a
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    • pp.132-134
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    • 2005
  • The CC chemokine, monocyte chemoattractant protein-1 (MCP-1), plays a crucial role in the initiation of atherosclerosis and has direct effects that promote angiogenesis. To develop a specific inhibitor for MCP-1-induced angiogenesis, we performed in vitro selection employing phage display random peptide libraries. Most of the selected peptides were found to be homologous to the second extracellular loops of CCR2 and CCR3. We synthesized the peptide encoding the homologous sequences of the receptors and tested its effect on the MCP-1 induced angiogenesis. Surface Plasmon Resonance measurements demonstrated specific binding of the peptide to MCP-1 but not to the other homologous protein, MCP-3. Flow cytometry revealed that the peptide inhibited the MCP-1 binding to THP-1 monocytes. Moreover, CAM and rat aortic ring assays showed that the peptide inhibited MCP-1 induced angiogenesis. Our observations indicate that the MCP-1-binding peptide exerts its anti-angiogenic effect by interfering with the interaction between MCP-1 and its receptor.

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A Study on the Carbonization Pattern Analysis of Ligth Emitting Diode Damaged by Outside Flame (외부화염에 의해 소손된 LED의 탄화 패턴 해석에 관한 연구)

  • Choi, Chung-Seog;Kim, Hyang-Kon
    • Proceedings of the KIEE Conference
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    • 2009.07a
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    • pp.2121_2122
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    • 2009
  • In this paper, we analyzed carbonization pattern of Ligth Emitting Diode(LED) lamp that become burnout by outside flame. Surface side can know that void is formed greatly than central part in section analysis of electric wire that is carbonized by outside flame. Chared globe displayed special quality that lump of abnormal carbonization falls was formed, and becomes melting among carbonization process. The LED resistance of forward direction is about 1.74 [$M{\Omega}$], and backward resistance is about 140 [$M{\Omega}$]. We can know progress direction of flame through measurement of the LED resistance.

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Amber Information Design to Keep Safety-Driving Under Road Structure at Local-Scale Geographic (국지지역 도로 기반 시설에서 안전운전을 위한 경보 정보 설계)

  • Park, Jung-Chan;Hong, Gyu- Jang
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.58 no.1
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    • pp.48-55
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    • 2009
  • In order to keep safe driving conditions under road networks, there are several formations such as road structure, road surface condition, traffic occupancy and supplement of an accurate information of traffic status ahead To support safe-driving on each road formation, each formation is supplied with various information to help the driver. However, in some cases like rapid status change at local-scale geography, traffic information systems often displays insufficient information because of the lack of information correlation. In order to accurately aware the driver, all road formation must be in sync. It is important to supply accurate information to the driver because this information directly impacts the drivers on the road. This paper discusses the amber information to keep the least safety driving over road formations including tunnels and bridges. This paper also will propose the informations for safe-driving conditions, information linkage on the road and rule-base safety information, as ITS technology, being displayed for all drivers under the worst weather conditions.

A Study on the Enhancement of Remote Sensing Image Using IHS Color Space (IHS 칼라공간에 의한 위성 영상 향상에 관한 연구)

  • 조석제
    • Journal of the Korean Institute of Navigation
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    • v.21 no.1
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    • pp.119-128
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    • 1997
  • Nowadays, many satellites regularly produce digital multispectral images of the earth's surface. Multispectral images may be displayed as color pictures by selecting three components for assignment to the primary colors. It is desired to enhance these images to generate a display picture that are representativde of their features. in this paper, a false color image processing algorithm is proposed for the purpose of enchancement of the multispectral images based on the human perception. The mean of each primary component is transformed to equalo. Intensity and saturation are enhanced by modified piecewise linear contrast strectching and saturation enhancement method. The proposed method has been successfully applied the LANDSAT TM image and shows good enhancement.

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Haptic display for deformable thin film (가변형 박판에 대한 촉감 제시)

  • 이승룡;최혁렬
    • 제어로봇시스템학회:학술대회논문집
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    • 1996.10b
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    • pp.125-129
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    • 1996
  • This paper presents the haptic rendering algorithm which gives the feel information to the operator by manipulating a virtual tool with a haptic device in the simulated environment. The movement of a virtual tool grasped by the operator, which is modeled as a square is displayed in the graphic screen of a computer and the virtual environment is modeled as deformable thin film. When the tool contacts with the virtual environment, the operator is forced to feel the contact and the feature of the deformed virtual environment through the torque control of th haptic device. Contact situations are modeled as close as to the reality considering friction, elasticity and multiple contacts. Several experiments are conducted and the effectiveness of the proposed algorithm is confirmed.

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Preparation of Composite Adsorbents by Activation of Water Plant Sludge and Phenolic Resin Mixtures

  • Myung, Heung-Sik;Kim, Dong-Pyo
    • Carbon letters
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    • v.1 no.3_4
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    • pp.154-157
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    • 2001
  • Composite adsorbents were prepared by mixing water plant sludge with phenolic resin having the ratio of 1 : 1, 1 : 2, and 1 : 3 respectively, curing from $100^{\circ}C$ to $170^{\circ}C$ under $N_2$ atmosphere, and then activating with $N_2$ at $700^{\circ}C$. Thermal property, specific surface area and morphology of the composite adsorbents as well as their precursors were measured by TGA, BET and SEM respectively. Removal efficiency of the composite adsorbents to ${NH_4}^+$ and TOC was compared with those of commercial zeolite and activated carbon. The adsorbents presented very promising TOC removal efficiency of 98%, which was identical level to that of commercial activated carbon while they displayed removal efficiency, only 32%, of ${NH_4}^+$. Therefore, this composite adsorbent considered as the alternative material of commercial activated carbon, used as an expensive removal agent of organic substances and THM in water treatment plant and it also suggested a possibility of practical application in other processes.

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Feature Extraction for Fault Signals of High Voltage Motor Stator Windings (고압전동기 결함신호의 특징추출에 관한 연구)

  • Park, Jae-Jun;Kim, Hee-Dong
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2004.07b
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    • pp.1154-1157
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    • 2004
  • During normal machine operation, partial discharge(PD) measurements were performed with turbine generator analyzer(TGA) in imitation stator winding of high voltage motors. The motor was energized to 4.47kV, 6.67, respectively. Applied voltage to Imitation winding was used two voltage level, 4.47[KV]and 6.67[KV]. Motors having imitation stator winding were installed with 80pF capacitive couplers at the terminal box Case of PD Pattern regarding applied voltage phase angel, the PD patterns were displayed two dimensional and three dimensional. TGA summarizes each plot with two quantities such as the normalized quantity number(NQN) and the peak PD magnitude(Qm). As the result, we could discrimidate using TGA the difference of internal and surface discharge for imitation stator winding. We have used the other technique, in order to feature extraction of faulty signals on stator winding, Daubechies Discrete wavelet transform and Harmonics analysis(FFT) about faulty signals.

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Development of Automatic Cam Profile Measurement System (자동 측정이 가능한 전용 캠 프로파일 측정 시스템 개발)

  • Jeong, Hwang-Young;Lee, Hyun-Seok;Park, Tae-Min;Shin, Woo-Cheol;Koh, Jun-Bin;Hong, Jun-Hee
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.17 no.1
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    • pp.106-112
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    • 2008
  • In this paper, It does the profile measurement of the cam of diesel engine SOHC of the actual object. It uses the measurement of run-out method. This method is that the surface of the object is measured by the sensor when the object rotate, and calculated and displayed by the computer the signal which acquired by sensor. When we acquire the signals, we have two error because of motion and contacting between cam and probe. In this paper, we compensate the motion error while simply liner equation. And we have a solution that we change the figure of probe when we have a contacting error. We compared the data measuring on developed automatic cam profile measuring system with the data measured on CMM.

Investigation of Sensitivity Distribution in THz Metamaterials Using Surface Functionalization

  • Cha, Sung Ho;Park, Sae June;Ahn, Yeong Hwan
    • Current Optics and Photonics
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    • v.3 no.6
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    • pp.566-570
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    • 2019
  • To investigate dependence of the sensitivity of THz metamaterials on the position of target dielectric materials, we functionalized the metamaterial gap with an adhesive polymer. A shift in resonance frequency occurs when polystyrene microbeads are deposited in the gap of the metamaterial's metal resonator pattern, while little change is observed when they are deposited on other areas of the metasurface. A two-dimensional mapping of the sensitivity, with a grid size of 1 ㎛, is obtained from a finite-difference time-domain simulation: The frequency shift is displayed as a function of the position of a target dielectric cube. The resulting sensitivity distribution clearly reveals the crucial role of the gap in sensing with metamaterials, which is consistent with the electric field distribution near the gap.

Development and Application of Biocompatible Polymers(III) - Biocompatibility of Silk Fibroin Membranes with Phosphoryl Choline Groups - (생체적합성 고분자의 개발과 응용(III) - Phosphoryl choline기를 가진 견피브로인막의 생체적합성 -)

  • Mi Kyung Lee;Young Hee Lee;Hae Wook Choi;Soo Min Park
    • Textile Coloration and Finishing
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    • v.7 no.3
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    • pp.38-43
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    • 1995
  • To improve the biofunctional properties of silk fibroin membranes, 2-(methacryloyloxy)ethyl-2-(trimethylammonium)ethyl phosphate(MTP), which is a methacrylate with phospholipid polar groups grafted and poly(MTP-co-BMA) was coated on the surface of silk fibroin membranes. The permeability and biocompatibility of silk fibroin membranes with phosphoryl choline group were investigated. The permeability of a salt(NaCl) was increased with grafting by MTP. Futhermore, the poly(MTP-co-BMA)-coated silk fibroin membranes displayed less blood cell adhesion than the silk fibroin membranes.

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