• Microbiology and Biotechnology Letters
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• v.49 no.2
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• pp.157-166
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• 2021

The probiotic market is constantly continuing to grow, concomitantly with a widening in the range and diversity of probiotic products. Probiotics are defined as live microorganisms that provide a benefit to the host when consumed at a proper dose; the viability of a probiotic is therefore of crucial importance for its efficacy. Many products undergo lyophilization for maintaining their shelf-life. Unfortunately, this procedure may damage the integrity of the cells due to stress conditions during both the freezing and (vacuum-) drying process, thereby impacting their functionality. We propose a lysine-based mixture for rehydration of freeze-dried probiotics for improving their viability during in vitro simulated gastric and duodenum stress conditions. Measurement of the zeta potential served as an indicator of cell integrity and efficacy of this mixture, while functionality was estimated by adhesion to a human enterocyte-like Caco-2 cell-line. The freeze-dried bacteria exhibited a significantly different zeta potential compared to fresh cultures; however, this condition could be restored by rehydration with the lysine mixture. Recovery of the surface charge was found to influence adhesion ability to the Caco-2 cell-line. The optimum lysine concentration of the formulation, designated "Zeta-bio", was found to be 0.03 M for improving the viability of Lactiplantibacillus plantarum Lp-115 by up to 13.86% and a 7-strain mixture (400B) to 41.99% compared to the control rehydrated with distilled water. In addition, the lysine Zeta-bio formulation notably increased the adherence ability of lyophilized Lp-115 to the Caco-2 cell-line after subjected to the in vitro stress conditions of the simulated gastrointestinal tract passage.

• The Journal of the Korean dental association
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• v.48 no.2
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• pp.106-112
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• 2010

Tissue engineering has been enhanced by advance in biomaterial nature, surface structure and design. In this paper, I report specifically vertically aligned titania ($TiO_2$) nanotube surface structuring for optimization of titanium implants utilizing nanotechnology. The formation, mechanism, characteristics of titania nanotubes are explained and emerging critical role in tissue engineering and regenerative medicine is reviewed. The main focus of this paper is on the unique 3 dimensional tubular shaped nanostructure of titania and its effects on creating epochal impacts on cell behavior. Particularly, I discuss how different cells cultured on titania nanotube are adhered, proliferated, differentiated and showed phenotypic functionality compared to those cultured on flat titanium. As a matter of fact, the presence of titania nanotube surface structuring on titanium for dental applications had an important effect improving the proliferation and mineralization of osteoblasts in vitro, and enhancing the bone bonding strength with rabbit tibia over conventional titanium implants in vivo. The nano-features of titania nanotubular structure are expected to be advantageous in regulating many positive cell and tissue responses for various tissue engineering and regenerative medicine applications.

• Textile Coloration and Finishing
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• v.25 no.4
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• pp.314-326
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• 2013

The purpose of this research is to analyze the effects of Dansam and Sappan wood extract to perform combination dyeing on silk fabrics, with respect to color changes, fastness (washing, dry cleaning, perspiration, rubbing and light fastness), and functionality (antibacterial activity and deodorization). Combination dyeing was performed by first combining Dansam with Sappan wood, then Sappan wood with Dansam, in these orders. Given the changes in the combination ratio, pre-mordant treatment was performed. Looking at the surface colors of each dye, Dansam generally produces YR color series, while Sappan wood produces YR, R, and RP color series. The effects of changing the order in which combination dying was performed on the surface colors were as follows. First, combination dyeing (A) was performed by using Dansam before Sappan wood, to produce YR and R color series. Then combination dyeing (B) was performed by using Sappan wood before Dansam, to produce YR, R, and RP color series. By visual inspections, more similar color changes of the combination dyeing were noticed with the post-dyeing material rather than the pre-dyeing material. Therefore, it was presumably confirmed that surface color changes of combination dyeing were greatly influenced by the post-dyeing color. Individual dyeing tests for fastness showed that Dansam was comparatively superior to Sappan wood, which demonstrated lower fastness to washing, dry cleaning, perspiration, and light, relatively. The fastness of combination dyed samples was shown middle, but similar fastness to the post-dye material, The fastness of (B) method was higher than (A) method in the washing and light fastness. This confirms that color fastness from combination dyeing was considerably influenced by the post-dye material. It was found that all dyed samples had a very high bacterial reduction rate of 99.9% and high deodorization rate of 95%.

• 제어로봇시스템학회:학술대회논문집
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• 2004.08a
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• pp.484-487
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• 2004

Symmetric directional couplers are widely used in interferometers, switches, and various signal processing devices. Recently, several optical couplers using multimode fibers were reported, but these suffer from inefficient coupling of light into a branching fiber and/or low directivity. This paper presents the measurement and analysis of loss in the connection of optical fibers via the optical directional couplers. The functionality of the device is based on the principle that is symmetrical, the power in excited mode can be unambiguously directed into one of the output channel by varying and of its parameters. In this experiment, we measure the power of loss in the optical directional coupler at various radius of curvature. Before the measurement of loss in x-coupler, we polish the contact of the fiber surface in order that light can penetrate through another port. The results show that, when the radius of curvature is increased, the loss power is decreased and also approaches of the straight line case.

• Proceedings of the Materials Research Society of Korea Conference
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• 2009.11a
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• pp.3.1-3.1
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• 2009

Nanotechnology has beenrapidly evolved from passive nanostructures where nanostructures with steadystructures and functions often used as parts of a product to activenanostructures which change their properties during use. Startingaround 2010, it is anticipated that researchers will cultivate expertise withsystems of nanostructures, directing large numbers of intricate components tospecified needs. One dimensional (1-D) nanostructures suchas nanowires and nanotubes are extremely attractive building blocks for nextgeneration devices because of their high surface to volume ratio and uniquesize dependent properties. In addition, their extremely high aspectratio offers researchers the potentials to build axial or radialheterostructures to integrate multiple functionality from intrinsic propertiesof the material or through interfacial phenomena. Spatialmanipulation and the ability to assemble and position nanostuructures in acontrolled matter so they are registered to define spaces is also a criticalstep toward scalable integration in high density nanodevices. In thispresentation, a generalized template directed electrodeposition with ancillaryassembly, contact will be presented to synthesize axial and radialheterostructures in cost-effective matter and these individual nanostructureswill be applied to spintronics, gas and biological sensors and thermoelectrics.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2006.05a
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• pp.59-62
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• 2006

This design plan aims at the presentation of the representative character of Design Center by making a new image of the cafeteria that is located in the 1. floor. To create an ambience of intercommunication and relaxation, it must be set up the basic concepts like Mobility, Flexibility, Transparence and Color-Play. As the design solutions : - first of all the 360 grade reversible and removable dividers are installed around the 5 pillars - in accordance with the basic concepts Mobility and Flexibility the cubic form construct that plays not only a role of a kitchen, but also a role of a counter, is designed to be relocated at one's own. - the various kinds of seating module and the chill-out zone are introduced to bring out the functionality and the aestheticity simultaneaously - to make a contrasting image to the glass surface of the yellow-, orange- and red-colored dividers, the black chairs and tables are arranged in the middle.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2006.11a
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• pp.193-196
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• 2006

The meaning of the color which has from modern interior space has played important role, i.e. color itself Is the concept creation tool as well as the unique expression sphere in field of interior space far away from fixed idea relevant to the existing color which was only simple decoration or secondary element in space. Thus, this current work expresses that the color is related with decoration effect as well as basic designed-conceptual work process including the space is formed. Furthermore, through the side-composition with color, It activates the various space aspect perceptually, which created the colorful environment in using lightning, reflection of glass and penetrated nature etc. The keyword on color concept is as like various aspects, third dimension, non-materiality and symbolical meaning. In addition, it provides the color space equipped with functionality and artistry capable to arouse the diverse sensual capacity to space users on default of color image language.

• Proceedings of the KWS Conference
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• 2006.05a
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• pp.16-17
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• 2006

We researched by the characteristic of a anisotropic etching of Si wafer and the Si career concerning the flip chip solder bump. Connectors and Anisotropic Conductive Film (ACF) method was already applied to board-to-board interconnection. In place of them, we have focused on board to board interconnection with solder bump by Si carrier, which has been used as Flip chip bonding technology. A major advantage of this technology is that the Flexible Printed Circuit (FPC) is connected in the same solder reflow process with other surface mount devices. This technology can be applied to semiconductors and electronic devices for higher functionality, integration and reliability.

• Journal of Ship and Ocean Technology
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• v.5 no.4
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• pp.1-18
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• 2001

Software written in academic environments is rarely integrated and/or reused. Moreover, typical academic software products do not communicate with commercial CAD packages, consequently functionality that is readily available to industry is not available do academic researchers. The Surface Design Library (SDL) is a library serving as a framework under which, CAGD software, intended for research or educational use, can be written in such a manner that it becomes a reusable part of a useful CAGD system. Moreover SDL is equipped with an IGES translator so that it communicates with commercial CAD packages, This paper gives a brief overview to SDL and presents examples of using it for high quality fairing performed on a naval ship hull, before employing commercial CAD packages for further design and analysis.

• 한국유가공학회:학술대회논문집
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• 2004.11a
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• pp.17-29
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• 2004

Nanofood can be simply defined as natural polymer particles containing functional food materials in nanoscale that are synthesized by polymerization or emulisification process. They have very uniform diameters in the range of 1 to 100 nm and extensive surface areas due to the small particle size in spite of their non-porosity. Although the technique to produce nanofood has not Bong developing history, many works have been achieved in various fields. Nanofood has a lot of special advantages, such as functionality, diversity, applicability, etc. In case of the domestic food industries, however, the accumulation of related technique is insufficient against developed countries except used food materials. Also, it is difficult to acquire technical know-how from the developed countries that possess those technologies. We have been studied on preparing functional nanofood and developing new production processes since 1999. Last 5 years we have laid the foundation on the preparation of nanofood and now are focusing on developing new processes of nanofood and expending the field of its applications.