• Proceedings of the KSAR Conference
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• 2001.03a
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• pp.19-19
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• 2001

Mammalian urothelium undergoes unique membrane specialization by making the asymmetric unit membrane (AUM) that is covered with the apical cell surface during terminal differentiation. The AUM contains several major integral membrane proteins including uroplakin Ia, Ib, II and III. The genes for uroplakins have been cloned from humans and mice, but not from porcine. In this study, we report the cloning of the UPII genomic DNA, which codes for the full length open reading frame for the uroplakin II protein. The deduced amino acid sequence encodes of a hydrophobic NH$_2$-terminal peptide, a prosequence, and a mature protein. The prosequence contains three potential N-glycosylation sites and a RGRR cleavage site that may be involved in uroplakin II processing and maturation. Northern and immunohistochemistry analyses showed that the porcine UPII gene is only expressed in urothelium and that the protein was specifically localized in urothelial superficial cells. A 2kb of upstream in the promoter sequence contains multiple transcription factor binding sites, including GC-box, SPI, AP2, and GATA-box sites, but not for TATA or CAAT-box sequences. Comparison of the porcine UPII promoter sequence with that of the murine by MEME system presented two conserved motifs, suggesting a cis-acting regulatory role for the conserved sequences. Sequence homology between two species in motif A and B was 79% and 80% respectively, although their relative locations were different. During the gestation, mouse bladder at estrus stages and day 10 after parturition showed higher UPII expression, while showed lower expression at peri-implantation stage. Taken together, our results showed that the porcine UPII gene was expressed highly and specifically in the bladder urothelium and that steroid hormones for implantation changed the expression of UPII in the bladder, although the biological significance of UPII remains to be not determined.

• The Journal of Engineering Geology
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• v.33 no.1
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• pp.137-149
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• 2023

In order to intuitively grasp the earth pressure direction acting on the structure and displacement state, displacement data in the horizontal and vertical directions were processed using the sigmoid function. A displacement coordinate system was set up for each axis. The system can intuitively check the current displacement and assess the management stage of each point. A displacement path can be compiled from continuously recorded points, allowing trends in the displacement's history and stress direction to be known. Analysis of data measured for excavated ground, found that displacement occurred in the direction of destressing at all points, and that the points' management state steady. Similar behavior trends were found among measurement points with high spatial correlation, whereas differing behavior trends occurred among measurement points with low spatial correlation. If the correlation analysis of the precursor and behavior area is performed using the continuously distributed surface settlement data and displacement coordinate system, it will be possible to predict the failure time and area.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.1C
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• pp.53-61
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• 2006

This study is aimed at to examine the stress redistribution mechanism for tunneling in an unconsolidated ground with inclined layers through model tests. To make the unconsolidated ground, two dimensional model ground is prepared with aluminum rods and blocks, which are frictional resistance free between testing apparatus walls and ground materials, by establishing the ground materials self-supporting. It is carried out to measure the ground deformation and the stress redistribution for model ground with tunneling by measuring apparatus respectively. For the ground deformation, surface settlements are measured to examine the deformation features during tunnel excavation. For the stress redistribution, the earth pressure acting on both the tunneling part and its surrounding parts is measured to examine their mutual relationship. Based on test results, precise examination is conducted on the stress redistribution mechanism in the unconsolidated ground with inclined layers during tunnel construction.

• Journal of The Korean Society of Agricultural Engineers
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• v.66 no.1
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• pp.39-48
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• 2024

Plastic greenhouses are simple structures consisting of lightweight materials such as steel pipes and polyvinyl chloride. However, serious damage occurs due to heavy winds and typhoon every year. To prevent a collapse of structural members, the Ministry of Agriculture and Rural Development has distributed plans and specifications for disaster-resistant standards. Despite these efforts, more than 50% of greenhouses still do not satisfy the disaster-resistant standards. Among the greenhouses that do not meet these standards, 85% are single-span greenhouses proposed 20 years ago. Consequently, there is a need to evaluate the safety of wind loads for the single-span greenhouse. Unfortunately, there are no design specifications for the greenhouses under wind loads. Therefore, a Korean design standard (KDS) has been utilized. KDS is defined with reference to wind speeds occurring once every 500 years, raising concerns about potential overdesign when considering the durability of plastic greenhouses. To address this, the modified wind load, considering the durability of the plastic greenhouse, was calculated, and a safety evaluation was conducted for sigle G-type plastic greenhouse. It was observed that the moment acting on the windward surface was substantial, and there was a risk of the foundation being pulled out if the basic wind speed exceeded 32 m/s. In terms of the combination strength ratio, it was less than 1.0 only on the leeward side when the basic wind speed was 24 m/s and 26 m/s. However, in all other cases, it exceeded 1.0, indicating an unsafe condition and highlighting the necessity for reinforcement.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.8 no.1
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• pp.87-95
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• 1988

In the arctic offshore regions, massive offshore gravity platforms are recommended to be construced because of severe environments. In such structures which is so large that its characteristic length is of the order of the wave length, wave-structure interaction problem has been solved using linear diffraction theory. Structural analysis of the large scale offshore structures requires wave force distribution along depth and wave pressure distribution on the body surface. In this study, existing computer program which calculates the total wave force acting on axisymmetric bodies has been modified to calculate wave force distribution along depth and wave pressure distribution on the body surface. Numerical results of pressure distribution for a fixed vertical cylinder obtained from this analysis has been compared with the results of an analytic solution of MacCamy-Fuchs, and good agreements has been obtained. It is desirable to use 6 in the case of analytic solution, and 5 in the case of numerical solution as the Fourier Mode of Green function. The results in this study are expected to be utilized for structural analysis such as pseudo-static analysis, dynamic analysis and fatigue analysis.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.11
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• pp.662-671
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• 2020

The uplift force acts directly on the foundation and causes a building to float to the upper ground. To examine the stability of a structure according to the uplift force, four sites (Paju, Anyang, Osan, and Gangneung) were selected, and sensors were installed on the foundations for the field tests. The rainfall characteristics were analyzed around June~September, and the changes in the water level of the adjacent river were considered. The maximum uplift force except for Gangneung did not exceed 72% of the water pressure when the groundwater level was up to the surface. On the other hand, the maximum uplift force in Osan was approximately 67%, but the reliability was slightly inferior because the difference from the average (46%) was large. The minimum uplift force was within 10% except for Anyang (~ 41%). At the Gangneung site on soft rock where the permanent drainage facility was installed before the measurement, the maximum and minimum uplift force was approximately 14% and 3.5%, respectively. Based on the measurement results, the possibility of overdesigning or underdesigning comes from the design by the hydrostatic pressure when the groundwater level is up to the surface.

• International Journal of Highway Engineering
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• v.12 no.1
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• pp.1-8
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• 2010

Construction of road closed to mountains is inevitable in Korea because the mountainous region in Korea is more than 70% in area. Recently, due to global warming, typhoons or heavy rainfalls frequently occur, and accordingly, mountain roads are seriously damaged by landslides, debris flows, and uplift pressure below pavement. in this study, damage on pavement by uplift pressure was investigated. Various influencing factors such as slope angle, reinforcement of slope surface, thickness of soil cover underlain by rock, and types of drainage system were considered to evaluate uplift pressure acting on the bottom of pavement. Raising of water table up to the surface of slope may depend on the duration and intensity of rainfall. It shows that the installation of subdrain can reduce the uplift water pressure. Therefore, It is concluded that the use of subdrain system is effective to decrease uplift pressure and cement treated base is more endurable than typical crushed-stone base.

• Journal of Korean Tunnelling and Underground Space Association
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• v.15 no.3
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• pp.237-251
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• 2013

This study aimed to estimate the axial stress and torque on a shaft in a disc cutter. The corresponding inner temperature and the surface temperature of a cutter ring were also measured by using strain gauges and thermocouples during the linear cutting tests. The maximum values of the axial stress and torque were recorded to 11.3 MPa, $171kN{\cdot}m$ respectively. They have higher correlations with normal force rather than rolling force. The results of temperature measured by thermocouples during a linear cutting test showed that the rate of increase in temperature was below $0.2^{\circ}C$. When the cutter spacing is set to be 70 mm, the inner temperature and surface temperature of a disc cutter were $0.1^{\circ}C/m$, $0.15{\sim}0.17^{\circ}C/m$ respectively. Similarly, when the cutter spacing is 90 mm, the temperature values were $0.09^{\circ}C/m$, $0.13{\sim}0.23^{\circ}C/m$ respectively.

• Journal of the Korean Society for Marine Environment & Energy
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• v.7 no.4
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• pp.192-198
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• 2004

A numerical method is developed to solve a two-dimensional diffraction problem for a body located in a sediment pocket where a heavier muddy water is trapped. In the present study, the wave exciting forces acting on a submerged body in the water-sediment interface by an incident wave is investigate. It is assumed that the heavier mud is trapped locally in a sediment pocket. A mathematical formulation is made in the scope of the potential theory. The fluid is assumed to be inviscid, incompressible and its motion irrotational. The boundary conditions on the unknown free surface and interface are linearized. As a method of solution, the localized finite-element method is adopted. In the method, the computation domain is reduced by utilizing the complete set of analytic solutions known in the infinite subdomain to be truncated by introduction of an appropriate juncture conditions. The main advantage of this method is that any complex geometry of the boundaries can be easily accommodated. Computations are carried out for mono-chromatic plane progressive surface waves normally incident on the domain. Numerical results are compared with those obtained by Lassiter based on Schwingers variational method. Good Agreements are obtained in general. Another numerical computations are made for the cases with and without a body in the sediment pocket.

• Clean Technology
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• v.17 no.4
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• pp.370-378
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• 2011

Catalytic activity of $V_2O_5-WO_3/TiO_2$-based SCR catalyst was examined for the oxidation of gas-phase elemental mercury to oxidized mercury. Mercury species was not detected on the commercial SCR catalyst after the oxidation reaction of elemental mercury, regadless of the presence of HCl acting as oxidant and the reaction conditions. This suggests that elemental mercury oxidation by HCl could occur via a Eley-Rideal mechanism with gas phase or weakly-bound mercury on the surface of $V_2O_5-WO_3/TiO_2$ SCR catalyst. The activity for mercury oxidation was significantly increased with the increase of $V_2O_5$ loading, which indicates that $V_2O_5$ is the active site. However, turnover frequency for mercury oxidation was decreased with the increase of $V_2O_5$ loading, indicating the activity for mercury oxidation was strongly dependent on the surface structure of vanadia species. The activity for oxidation of elemental mercury under SCR condition was much less than that under oxidation condition at the same HCl concentration and reaction temperature.