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Skin Absorption and Physical Property of Ceramide-added Ethosome (세라마이드 함유 에토좀의 물성과 피부흡수)

  • Hyeon, Tong-Il;Yoon, Kyung-Sup
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.3
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    • pp.801-812
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    • 2021
  • In order to delivery biotin to skin, ethosomes containing both biotin and ceramide were researched by using high pressure homogenizer. Biotin was utilized as a drug and ceramide NP was utilized as a supporter of bilayer. The biotin was entrapped in aqueous core, while ceramide NP was packed in the bilayer of the ethosomes. Looking at the physical properties of vesicles containing ceramide NP, the sized was 80~130 nm, the polydispersity index was 0.09~0.16, and the zeta potential was -40~-49 mV. In vesicles without ceramide NP, the size was 124.80±1.46 nm, and the zeta potential and polydispersity index were -45.48±1.27 mV and 0.088±0.018, respectively. Therefore, the ethosome with ceramide NP has improved physical properties of vesicles compared to the ethosome without ceramide NP. Skin absorption rates of ethosomes with ceramide NP were 6.13~14.98%, while skin absorption rate of ethosome without ceramide NP was 7.08% at 12 h. In conclusion, ethosomes containing ceramide NP not only improved the skin absorption efficiency, but had also a positive effect on the stability of vesicles.

Effect of Powder Condition on the Fire and Explosion Characteristics of Suspended and Deposited Dusts (부유 및 퇴적의 분체 조건이 화재폭발 특성에 미치는 영향)

  • Han, Ou-Sup;Seo, Dong-Hyun;Choi, Yi-Rac;Lim, Jin-Ho
    • Korean Chemical Engineering Research
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    • v.60 no.2
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    • pp.229-236
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    • 2022
  • An experimental investigation was conducted on the influences of median size, dust concentration, dust condition (cloud and layer) for the fire and explosion hazard assessment of dusts with the same powder property. For this purpose, tests have been performed in accordance with 20 L explosion sphere, thermogravi- metric analyze, combustion rate tester (UN method). We investigated the explosion characteristics and flame propagation velocity (FPV) in dust cloud and the flame spread velocity(FSV) over dust layer on 8 dust samples with different particle sizes of 4 types of dusts (Sugar, Mg, Al, Zr). An explosion hazard increased with decreasing particle size in Mg and Al dust clouds, but sugar did not show the effect of explosion hazard due to particle size change in dust clouds. The flame propagation velocity (FPV) of suspended dusts increased significantly when the particle size decreased from micro to nano than the variation of particle size in micro range. The flame spread velocity (FSV) over dust layer showed a tendency to increase over the inclined dust layers (30° slope) rather than the horizontal dust layers (0° slope). The flame spread rate (FSV) over dust layers increased on the inclined dust layer (30° slope) rather than the horizontal dust layer (0° slope) and was higher upward flame than the downward flame in condition of inclined dust layers(30° slope).

Flood Mapping Using Modified U-NET from TerraSAR-X Images (TerraSAR-X 영상으로부터 Modified U-NET을 이용한 홍수 매핑)

  • Yu, Jin-Woo;Yoon, Young-Woong;Lee, Eu-Ru;Baek, Won-Kyung;Jung, Hyung-Sup
    • Korean Journal of Remote Sensing
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    • v.38 no.6_2
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    • pp.1709-1722
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    • 2022
  • The rise in temperature induced by global warming caused in El Nino and La Nina, and abnormally changed the temperature of seawater. Rainfall concentrates in some locations due to abnormal variations in seawater temperature, causing frequent abnormal floods. It is important to rapidly detect flooded regions to recover and prevent human and property damage caused by floods. This is possible with synthetic aperture radar. This study aims to generate a model that directly derives flood-damaged areas by using modified U-NET and TerraSAR-X images based on Multi Kernel to reduce the effect of speckle noise through various characteristic map extraction and using two images before and after flooding as input data. To that purpose, two synthetic aperture radar (SAR) images were preprocessed to generate the model's input data, which was then applied to the modified U-NET structure to train the flood detection deep learning model. Through this method, the flood area could be detected at a high level with an average F1 score value of 0.966. This result is expected to contribute to the rapid recovery of flood-stricken areas and the derivation of flood-prevention measures.

Influence of Glass Dielectric Property on the External Electrode Fluorescent Lamps (유리관의 유전 특성이 외부전극 형광램프에 미치는 영향)

  • Shin, Myeong-Ju;Jeong, Jong-Mun;Kim, Jung-Hyun;Kim, Ga-Eul;Lee, Mi-Ran;Yoo, Dong-Gun;Koo, Je-Huan;Hong, Byoung-Hee;Choi, Eun-Ha;Cho, Guang-Sup
    • Journal of the Korean Vacuum Society
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    • v.16 no.5
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    • pp.330-337
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    • 2007
  • Influence of glass dielectric property (dielectric constant K, dielectric loss) on the external electrode fluorescent lamps of the dielectric barrier discharge has been investigated with 4-different glasses. Conventional borosilicate glass tubes with $K=5.6{\sim}5.9$ and tan ${\delta}=5.0{\times}10^{-3}{\sim}6.0{\times}10^{-3}$ and aluminosilicate glass tubes with high K=6.6 and low tan ${\delta}=1{\times}10^{-4}$ and soda-lime glass tribes with K=7.7 and tan ${\delta}=1.37{\times}10^{-2}$ have been compared. The high value of dielectric constant K makes the capacitance of external electrode fluorescent lamps intensity and enhances the discharge efficiency. The dielectric loss of tan ${\delta}$ shows the factor of power consumption in the external electrode to induce heats and to be weak in pinhole stability. The aluminosilicate glass tubes of high K and low tan ${\delta}$ have been enhanced by $14{\sim}18%$ in luminance and efficiency in comparison with the conventional borosilicate glass tubes and the aluminosilicate external electrode fluorescent lamps are strong against the pinhole formation. Soda-lime glass tubes with high K and high tan ${\delta}$ are a little favorable in luminance and efficiency and they are very weak in pinhole occurrence.

Types of Scenic Sites of State-Designated Cultural Property and Relationship between Pal-Kyung and Doncheon-Gugok (국가 지정 문화재 '명승'의 유형과 팔경(八景), 동천구곡(洞天九曲)과의 연관성)

  • Rho, Jae Hyun;Shin, Sang Sup
    • Korean Journal of Heritage: History & Science
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    • v.43 no.1
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    • pp.128-159
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    • 2010
  • In this study, the progress of domestic cultural properties designation, the changes and problems in classification were examined, and the relationship among Traditional Pal-kyung, Dongcheon-gukok, and Modern Pal-kyung were investigated targeting total of 68 cases of state-designated cultural properties of scenic sites in order to show that the traditional significance and value are being inherited today. The major results of this study are as follows. First, increase in scenic site designations with historical, cultural, and scenic characteristics can be viewed as an active intent to embrace the concepts such as cultural utilities, historical characteristics, literary value, and ideological backgrounds, which were specified as the basis for designation in the early Cultural Property Protection Law. Accordingly, it is very encouraging that the concept of cultural attractions such as traditional gardens and observatory points are regarded as an important standard for designation of scenic sites. Second, as for the classification of scenic sites per type, it was found that 'places with excellent natural scenery' were 44.16%(30 cases), followed by 'famous buildings or gardens and places with important legend' occupying 30.9%(21 cases), 'places with famous scenery' occupying 13.2%(9 cases), 'places with outstanding historical cultural and scenic value' that occupying 10.3%(7 cases), and 'animal and vegetation habitat with beautiful scenery' (1 case). Third, according to the current classification standards for scenic sites, there were only 7 cases which could be classified into Pal-kyungs(Famous 8 Sceneries) and 3 cases classified into Dongcheon(beautiful scenery surrounded by mountains and rivers), but there was no Gugok(beautiful valleys). Consequently, in terms of external appearance, the scenic sites among the total scenic sites that could be classified into Palkyung and Gugok were only 14.7%(10 cases). Fourth, the traditional scenic sites based on literal references and Internet analysis occupied 67.7%(46 cases), which were found to be scenic sites related to the traditional Pal-kyung among which 38 cases(55.9% of 46 cases) were included based on the scenery and 8 cases(11.8% of 46 cases) were included due to the scenery at the time. Fifth, there were 8(11.8%) scenic sites which were related to Dongcheon, and 4 cases(5.9%) related to Gugok. Also, it was found that total of 40(48.9%) scenic sites designated as modern scenic sites were playing the role of local scenic sites, and they were used as the tourism advertising contents. Sixth, it was identified that there were 62 cases(91.2%) of scenic sites in total related to traditional and modern Pal-kyung or Dongcheon-gugok, and unlike explicit classifications, most of the designated scenic sites were found to be deeply connected with the historical and cultural significance contained in the scenaries.

Study on the production of porous CuO/MnO2 using the mix proportioning method and their properties (반응몰비에 따른 다공성 CuO/MnO2의 제조 및 특성 연구)

  • Kim, W.G.;Woo, D.S.;Cho, N.J.;Kim, Y.O.;Lee, H.S.
    • Analytical Science and Technology
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    • v.28 no.3
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    • pp.182-186
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    • 2015
  • In this study, the porous CuO/MnO2 catalyst was prepared through the co-precipitation process from an aqueous solution of potassium permanganate (KMnO4), manganese(II) acetate (Mn(CH3COO)2·4H2O) and copper(II) acetate (Cu(CH3COO)2·H2O). The phase change in MnO2 was analyzed according to the reaction molar ratio of KMnO4 to Mn(CH3COO)2. The reaction mole ratio of KMnO4 to Mn(CH3COO)2·4H2O was varied at 0.3:1, 0.6:1, and 1:1. The aqueous solution of Cu(CH3COO)2 was injected into a mixed solution of KMnO4 and Mn(CH3COO)2 to 10~75 wt% relative to MnO2. The Cu ion co-precipitates as CuO with MnO2 in a highly dispersed state on MnO2. The physicochemical property of the prepared CuO/MnO2 was analyzed by using the TGA, DSC, XRD, SEM, and BET. The different phase types of MnO2 were prepared according to the reaction mole ratio of KMnO4 to Mn(CH3COO)2·4H2O. The results confirmed that the porous CuO/MnO2 catalyst with γ-phase MnO2 was produced in the reaction mole ratio of KMnO4 to Mn(CH3COO)2 as 0.6:1 at room temperature.

The Planting and Occurrence Status of Exotic Plants of the Folk Village as National Cultural Heritage - Focus in Hahoe.Yangdong.Hangae Villages - (국가지정 문화재 민속마을의 외래식물 식재 및 발생현황 - 하회.양동.한개마을을 대상으로 -)

  • Rho, Jae-Hyun;Oh, Hyun-Kyung;Han, Yun-Hee;Park, Kyung-Uk;Byun, Moo-Sup;Huh, Joon;Choi, Yung-Hyun;Shin, Sang-Sup;Lee, Hyun-Woo;Kim, Hyo-Jung
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.31 no.2
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    • pp.1-19
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    • 2013
  • This study was carried out to analyze distribution situation of alien plants and to propose management plan in the 3 Folk village in Gyeongsangbuk-do which is Cultural property designated by the State; Hahoe, Yangdong and Hangae. This research is for improve of sincerity of historical site and provide basic information which use about administration of preservation. The results are as follows. 1. Overall flora and alien plants appearance The total flora in the 3 folk villages were listed total 752 taxa including 127 families, 430 genera, 614 species, 5 subspecies, 100 varieties and 33 forms. Among them, woody plants take 263 taxa(35.0%) and herbaceous plants take 489 taxa (65.0%). Flora in the Hahoe, Yangdong and Hangae village were total 534, 479 taxa and 408 taxa and exotic plant index was 30.1%, 38.2% and 37.0% respectively. In types of exotic plants, ornamental exotic plants were 135 taxa, deciduous exotic plants were 21 taxa, cultivating exotic plants were 64 taxa, and naturalized exotic plants were 80 taxa and those result lead that the ornamental exotic plants is the highest ratio. According to the villages, Hahoe village had 161 taxa(30.1%), Yangdong Village had 183 taxa(38.2%), and Hangae village had 151 taxa(37.0%) that Yangdong village showed the most number of exotic plants. 2. Planting of landscape exotic plants in the unit cultural assets Meanwhile, Ornamental exotic plants in old house's gardens in Andong Hahoe village which is designated as a unit assets, those are total 30 taxa; followed by the Okyeon house(8 taxa) is highest and the Yangjindang(7), the Hadong house(6) and the Chunghyodang(5). Magnolia denudata appears the most as for 4 times and Campsis grandiflora etc. each took 2 times. Based on the Yangdong village, Gyeongju, that are found total 51 taxa; followed by the Dugok house(16 taxa) the Sujoldang(14), the Mucheondang(13), and the Sangchunheon (12). High appearance rate of ornamental exotic plants were Viburnum opulus for. hydrangeoides, Lycoris squamigera, Caragagna sinica and Magnolia denudata etc. Based on the Hangae village, Seongju, that are designated total 62 taxa; followed by the Jinsa house(35 taxa), the Gyori house(25), the Hanju head family house(20), and the Hahoe house(16). Taxa with high appearance rates were Caragana sinica, Juniperus chinensis var. horizontalis, Magnolia denudata, Viburnum opulus for. hydrangeoides, Chaenomeles speciosa etc. 3. Problems of exotic plant landscapes in the outer spaces of the folk villages Problems of exotic plant landscapes in the outer spaces of the Hahoe village are as follows. In lower of the Mansongjeong forest, Ambrosia artemisifolia, which are ecosystem disturbance plants designated by the Ministry of Environment, live with high dominance value. This should be have a remove with Sicyos angulatus immediately. In the Nakdong river bed around the Mansongjeong forest is covered with a riparian vegetation forest belt of Robinia pseudoacacia L. forest, Populus nigra var. italic community, and Populus x tomentiglandulosa community colony. Based on the Yangdong village, the planted or naturally distributed Ailanthus altissima colony, sporadically distributed Robinia pseudoacacia as well as Amorpha fruticosa are detected all over the village and ecotones. Based on the Hangae village, Ailanthus altissima and Robinia pseudoacacia are sporadically distributed around the village and there is a sign of spreading. similarity of exotic plantsis 47.0% to 48.6% and a reason why this happened is all of research site in Gyeongsanbuk-do and that is why growth norm of plant is similar, exotic plant which is sales for ornamental and it infer to require related countermeasure of each villages and joint related countermeasure.

A Study on the Funerary Mean of the Vertical Plate Armour from the 4th Century - Mainly Based on the Burial Patterns Shown by the Ancient Tombs No.164 and No.165 in Bokcheon-dong - (종장판갑(縱長板甲) 부장의 다양성과 의미 - 부산 복천동 164·165호분 출토 자료를 중심으로 -)

  • Lee, Yu Jin
    • Korean Journal of Heritage: History & Science
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    • v.44 no.3
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    • pp.178-199
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    • 2011
  • The ancient tombs found in Bokcheon-dong, Busan originate from the time between the $4^{th}$ and $5^{th}$ centuries, the period of the Three Nations. They are known as the tombs where the Vertical Plate Armour was mainly buried. In 2006, two units of the Vertical Plate Armour were additionally investigated in the tombs No.164 and No.165 which had been constructed at the end of the eastern slope near the hill of the group of ancient tombs in Bokcheon-dong. Throughout this study, the contents of the two units of the Vertical Plate Armour, whose preservation process has been completed, have been arranged, while the group of constructed ancient tombs in Bokcheon-dong from the $4^{th}$ century has been observed through the consideration of the burial pattern. The units of the Vertical Plate Armour from the tombs No.164 and No.165 can be classified as the IIa-typed armor showing the Gyeongju and Ulsan patterns, according to the attribute of the manufacturing technology. Also, they can be chronologically recorded as those from the early period of Stage II among the three stages regarding the chronological recording of the Vertical Plate Armour. While more than two units of the Vertical Plate Armour were buried in the largesized tomb on the top of the hill of the group of ancient tombs, one unit of the Vertical Plate Armour was buried in the small-sized tomb. By considering such a trend, it can be said that in the stage of burying the armor showing the Gyeongju and Ulsan patterns (I-type and IIa-type), different units of the Vertical Plate Armour were buried according to the size of the tomb. However, as the armor showing the Busan pattern (IIb-type) was settled, only one unit was buried. Meanwhile, the tombs No.164 and No.165 can be included in the wooden chamber tomb showing the Gyeongju pattern, which is a slender rectangular wooden chamber tomb with the aspect ratio of more than 1:3. However, according to the trend shown by the buried earthenware, it can be said that there seem to be common types and patterns shared with the earthenware which has been found in the area of Gimhae and is called the one showing the Geumgwan Gaya pattern. In other words, there seem to be close relationships between the subject tombs and the tomb No.3 in Gujeong-dong and the tomb No.55 in Sara-ri, Gyeongju, regarding the types of armor and tombs and the arrangement of buried artifacts. However, the buried earthenware shows a relationship with the areas of Busan and Gimhae. By considering the combined trend of the Gyeongju and Gimhae elements found in one tomb, it is possible to assume that the group of constructed ancient tombs in Bokcheon-dong used to be actively related with both areas. It has been thought that the Vertical Plate Armour used to be the exclusive property of the upper hierarchy until now, since it was buried in the large-sized tomb located on the top of the hill of the group of ancient tombs in Bokcheondong. However, as shown in case of the tombs No.164 and No.165, it has been verified that the Vertical Plate Armour was also buried in the small-sized tomb in terms of such factors as locations, sizes, the amount of buried artifacts and the qualitative aspect. Therefore, it is impossible to discuss the hierarchical characteristic of the tomb just based on the buried units of the Vertical Plate Armour. Also, it is difficult to assume that armor used to symbolize the domination of the military forces. The hierarchical characteristic of the group of constructed ancient tombs in Bokcheon-dong from the $4^{th}$ century can be verified according to the location and size of each tomb. As are sult, the re seem to be some differences regarding the buried units of the vertical plate armour. However, it would be necessary to carry out amore multilateral examination in order to find out whether the burial of the vertical plate armour could be regarded as the artifact which symbolizes the status or class of the deceased.

Optical Property of Super-RENS Optical Recording Ge2Sb2Te5 Thin Films at High Temperature (초해상 광기록 Ge2Sb2Te5 박막의 고온광물성 연구)

  • Li, Xue-Zhe;Choi, Joong-Kyu;Lee, Jae-Heun;Byun, Young-Sup;Ryu, Jang-Wi;Kim, Sang-Youl;Kim, Soo-Kyung
    • Korean Journal of Optics and Photonics
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    • v.18 no.5
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    • pp.351-361
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    • 2007
  • The samples composed of a GST thin film and the protective layers of $ZnS-SiO_2$ or $Al_2O_3$ coated on c-Si substrate were prepared by using the magnetron sputtering method. Samples of three different structures were prepared, that is, i) the GST single film on c-Si substrate, ii) the GST film sandwiched by the protective $ZnS-SiO_2$ layers on c-Si substrate, and iii) the GST film sandwiched by $Al_2O_3$ protective layers on c-Si substrate. The ellipsometric constants in the temperature range from room temperature to $700^{\circ}C$ were obtained by using the in-situ ellipsometer equipped with a conventional heating chamber. The measured ellipsometric constants show strong variations versus temperature. The variation of ellipsometric constants at the temperature region higher than $300^{\circ}C$ shows different behaviors as the ambient medium is changed from in air to in vacuum or the protective layers are changed from $ZnS-SiO_2$ to $Al_2O_3$. Since the long heating time of 1-2 hours is believed to be the origin of the high temperature variation of ellipsometric constants upon the heating environment and the protective layers, a PRAM (Phase-Change Random Access Memory) recorder is introduced to reduce the heating time drastically. By using the PRAM recorder, the GST samples are heated up to $700^{\circ}C$ decomposed preventing its partial evaporation or chemical reactions with adjacent protective layers. The surface image obtained by SEM and the surface micro-roughness verified by AFM also confirmed that samples prepared by the PRAM recorder have smoother surface than the samples prepared by using the conventional heater.

Establishment of Database System for Radiation Oncology (방사선 종양 자료관리 시스템 구축)

  • Kim, Dae-Sup;Lee, Chang-Ju;Yoo, Soon-Mi;Kim, Jong-Min;Lee, Woo-Seok;Kang, Tae-Young;Back, Geum-Mun;Hong, Dong-Ki;Kwon, Kyung-Tae
    • The Journal of Korean Society for Radiation Therapy
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    • v.20 no.2
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    • pp.91-102
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    • 2008
  • Purpose: To enlarge the efficiency of operation and establish a constituency for development of new radiotherapy treatment through database which is established by arranging and indexing radiotherapy related affairs in well organized manner to have easy access by the user. Materials and Methods: In this study, Access program provided by Microsoft (MS Office Access) was used to operate the data base. The data of radiation oncology was distinguished by a business logs and maintenance expenditure in addition to stock management of accessories with respect to affairs and machinery management. Data for education and research was distinguished by education material for department duties, user manual and related thesis depending upon its property. Registration of data was designed to have input form according to its subject and the information of data was designed to be inspected by making a report. Number of machine failure in addition to its respective repairing hours from machine maintenance expenditure in a period of January 2008 to April 2009 was analyzed with the result of initial system usage and one year after the usage. Results: Radiation oncology database system was accomplished by distinguishing work related and research related criteria. The data are arranged and collected according to its subjects and classes, and can be accessed by searching the required data through referring the descriptions from each criteria. 32.3% of total average time was reduced on analyzing repairing hours by acquiring number of machine failure in addition to its type in a period of January 2008 to April 2009 through machine maintenance expenditure. Conclusion: On distinguishing and indexing present and past data upon its subjective criteria through the database system for radiation oncology, the use of information can be easily accessed to enlarge the efficiency of operation, and in further, can be a constituency for improvement of work process by acquiring various information required for new radiotherapy treatment in real time.

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