• Title/Summary/Keyword: suitability analysis

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Development and validation of a HPLC method for the simultaneous determination of chlorquinaldol and promestriene in complex prescription (복방제제 내 클로르퀴날돌과 프로메스트리엔에 대한 HPLC 기반 동시분석법의 개발 및 밸리데이션)

  • Lee, Seul-Ji;Shin, Sang-Yeon;Shin, Hae-Jin;Lee, Jin-Gyun;Kim, Dong-Hwan;Lee, Su-Jung;Han, Sang-Beom;Park, Jeong-Hill;Lee, Jeong-Mi;Kwon, Sung-Won
    • Analytical Science and Technology
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    • v.25 no.2
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    • pp.152-157
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    • 2012
  • Currently, many types of compound preparations are being used but the quality control guidelines for their use are lacking. In case of single compound drug, the quality control methods are specified in the pharmacopeia. However, there is no method to simultaneously analyze compound preparations. In this study, a simple validated analytical method for HPLC separation of chlorquinaldol and promestriene is introduced. Validation was divided into categories including linearity, precision, accuracy (recovery) and system suitability. The contents of the products which are on the market were monitored using the validated analytical method and the robustness of the analytical method was tested by conducting an inter-laboratory validation.

Construction of a Microsatellite Marker Database of Commercial Pepper Cultivars (유통 중인 고추 품종에 대한 Microsatellite 마커 Data Base 구축)

  • Kwon, Yong-Sham;Hong, Jee-Hwa;Choi, Keun-Jin
    • Horticultural Science & Technology
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    • v.31 no.5
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    • pp.580-589
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    • 2013
  • This study was carried out to evaluate the suitability of microsatellite markers for varietal identification and genetic relationship of 170 commercial pepper cultivars. The relationship between marker genotypes and 11 pepper cultivars with different morphological traits was also analyzed. Of the 302 pairs of microsatellite primers screened against 11 pepper cultivars, 24 pairs were highly polymorphic in terms of number of alleles. These markers were applied for the construction of DNA profile data base for 170 commercial pepper cultivars. A total of 164 polymorphic amplified fragments were obtained from 24 microsatellite primers. The average polymorphism information content was 0.673 ranging from 0.324 to 0.824. One hundred and sixty four microsatellite alleles were used to calculate Jaccard's distance coefficients using unweighted pair group method. A clustering group of varieties, based on the results of microsatellite analysis, were categorized into 3 major groups corresponding to morphological traits. The phenogram discriminated all varieties by markers genotypes. These microsatellite markers will be useful as a tool for protection of plant breeders' intellectual property rights through variety identification in distinctness, uniformity and stability test.

A Feasibility Study for Evaluation Measurement of IT Outsourcing Service Quality applied on KS-SQI (KS-SQI를 적용한 IT아웃소싱 서비스품질 평가도구에 관한 적합성 연구)

  • Shin, Mi-Hyang
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.11
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    • pp.4778-4787
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    • 2011
  • The purpose of this study to develop IT Outsourcing service quality evaluation measurement have been frequently used to apply a model KS-SQI in the service industry. Primary needs fulfillment, unexpected benefits, reliability, individual empathy, positive assistance, accessibility and physical environment were selected as independent variable, they evaluate IT outsourcing service quality in order to verify their suitability as a tool for IT outsourcing service evaluation measurement, to analyze how that affects IT outsourcing satisfaction, and to investigate whether affecting IT outsourcing satisfaction on recontract intentions. To validate the hypothesis by path analysis conducted between variables using LISREL, primary needs fulfillment, reliability, individual empathy, positive assistance, accessibility and physical environment have significant effect on IT outsourcing satisfaction, but unexpected benefits don't have effect on IT outsourcing satisfaction, and IT outsourcing satisfaction showed significant effect on recontract intentions. Six Measurement tools has been proved to be suitable as a IT outsourcing service quality evaluation tool. Contribution of this study to evaluate the quality of IT outsourcing services, KS-SQI model developed by applying the measuring tool was achieved theoretical extensions and practical aspects of a recontract with the provider of IT outsourcing and IT outsourcing services for as a tool to assess the quality of can be used.

An appropriateness review on the road tunnel ventilation standards by pollutants site measurement and case study (오염물질 현장측정 및 사례조사를 통한 도로터널 환기기준의 적정성에 관한 연구)

  • Kim, Hyo-Gyu;Baek, Doo-San;Yoo, Ji-Oh
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.22 no.3
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    • pp.323-335
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    • 2020
  • In this study, a series of site measurement of particulate and gases pollutants at five tunnels were carried out along with case studies to review the suitability of the current road tunnel ventilation design standards. Previous studies by other researchers have shown that the ratios of the level of measurement to the standard were 27.9%, 1.6% and 3.4% for TSP, CO and NOx, respectively. Those measured in this site study shows even lower ratios; the ratios were 2.6%, 0.8% and 0.3%, for TSP, CO and NOx, respectively. The particle size analysis of TSP for the five tunnels shows that PM10 including tire wear and re-suspended road dust exceeded 20.4%. This implies that non-exhaust particulate matter must be taken into account, since the current design standards for the particulate matter (visibility) include only the engine emission. Based on the recent research results, for vehicle emission rate and slope-speed correction factors, revision of ventilation design standards for pollutants is required. WRA (PIARC) also emphasizes the necessity of the ventilation design standards for pollutants. In addition, enactment of a new road tunnel ventilation system operation standard or guideline is strongly recommended when considering the low operating rate of the ventilation system with jet-fans.

Development of Rashguard Swimwear Size System and Pattern for Middle-aged Women in Breast Cancer Patients

  • Han, Hyun-Sook;Sohn, Boo-Hyun
    • Journal of the Korea Society of Computer and Information
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    • v.25 no.6
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    • pp.155-164
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    • 2020
  • In this paper, we proposed the dimensional system and pattern of middle-aged women's rashguard swimwear for breast cancer patients. First, a survey of 37 breast cancer patients was conducted to determine the preferred swimsuit design for breast cancer patients. According to a survey of breast cancer patients, a rashguard swimwear with a low-exposure chest was designed. It has a pocket shape in which the cap is easy to insert and the cap is fixed. Second, we developed a dimensional system for swimsuits for breast cancer patients. Using direct measurement data from Size Korea for 1,625 women aged 30 to 69, 17-sizes for breast cancer patient's swimsuits were set through cross-analysis of major dimensions, with a coverage rate of 74.3%. It also extracted a standard size of bust circ. 90cm, hip circ. 95cm, and trunk circ. 150cm. Third, we developed a pattern for the central size of the swimsuit for breast cancer patients. For this purpose, we first produced the first central size pattern, and then completed the pattern after modifying it through the second and third wearing experiments. Experimental suits were produced at each pattern-making stage to evaluate wearing fit and motion suitability. Finally, the reduction rate of each dimension item for optimal pattern production was obtained, and the lashguard swimwear pattern for breast cancer patients was developed.

Synthesis and Biocompatibility Study of Hydrogel for Patch Sensor in Non-invasive Glucose Monitoring System (무채혈 혈당 측정시스템의 Patch Sensor용 수화젤의 합성 및 생체적합성에 관한 연구)

  • Kwon, Jeong-Woo;Kim, Dong-Chul;Yoon, In-Joon;Jeong, Yoon-Na;Jeong, Ji-Young;Hwang, In-Sik
    • Polymer(Korea)
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    • v.33 no.2
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    • pp.111-117
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    • 2009
  • This study aims to verify for humans the suitability of the enzyme-fixed hydrogel used for the patch sensor of the blood sugar testing system without blood sampling, which utilizes reverse iontophoresis. Using acrylate monomers, hydrogel was synthesized to which a certain unit of enzyme is fixed. In order to analyze the material property of the synthesized hydrogel, a structural analysis was performed using FT-IR spectroscopy, while the DSC was used to verify the thermal stability. In addition, with the UV-Vis spectrophotometer, it was verified that the degree of active enzyme is at least 50% greater than the standard product. The SEM was used to verify secure fixation of the enzyme onto the surface. As a result, it was observed that the enzyme is successfully fixed to the surface. Since the hydrogel makes direct contact with a patient's skin, it is essential to evaluate the toxicity when making direct contact with the skin. For that purpose, various sets of tests were undertaken according to the ISO 10993-cytotoxicity, intracutaneous reactivity, skin irritation test and maximization sensitization. Consequently, it was successfully verified that the enzyme-fixed hydrogel have bioavailability.

An Educational Case Study of Image Recognition Principle in Artificial Neural Networks for Teacher Educations (교사교육을 위한 인공신경망 이미지인식원리 교육사례연구)

  • Hur, Kyeong
    • Journal of The Korean Association of Information Education
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    • v.25 no.5
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    • pp.791-801
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    • 2021
  • In this paper, an educational case that can be applied as artificial intelligence literacy education for preservice teachers and incumbent teachers was studied. To this end, a case of educating the operating principle of an artificial neural network that recognizes images is proposed. This training case focuses on the basic principles of artificial neural network operation and implementation, and applies the method of finding parameter optimization solutions required for artificial neural network implementation in a spreadsheet. In this paper, we focused on the artificial neural network of supervised learning method. First, as an artificial neural network principle education case, an artificial neural network education case for recognizing two types of images was proposed. Second, as an artificial neural network extension education case, an artificial neural network education case for recognizing three types of images was proposed. Finally, the results of analyzing artificial neural network training cases and training satisfaction analysis results are presented. Through the proposed training case, it is possible to learn about the operation principle of artificial neural networks, the method of writing training data, the number of parameter calculations executed according to the amount of training data, and parameter optimization. The results of the education satisfaction survey for preservice teachers and incumbent teachers showed a positive response result of over 70% for each survey item, indicating high class application suitability.

A Study on Condition Analysis of Revised Project Level of Gravity Port facility using Big Data (빅데이터 분석을 통한 중력식 항만시설 수정프로젝트 레벨의 상태변화 특성 분석)

  • Na, Yong Hyoun;Park, Mi Yeon;Jang, Shinwoo
    • Journal of the Society of Disaster Information
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    • v.17 no.2
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    • pp.254-265
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    • 2021
  • Purpose: Inspection and diagnosis on the performance and safety through domestic port facilities have been conducted for over 20 years. However, the long-term development strategies and directions for facility renewal and performance improvement using the diagnosis history and results are not working in realistically. In particular, in the case of port structures with a long service life, there are many problems in terms of safety and functionality due to increasing of the large-sized ships, of port use frequency, and the effects of natural disasters due to climate change. Method: In this study, the maintenance history data of the gravity type quay in element level were collected, defined as big data, and a predictive approximation model was derived to estimate the pattern of deterioration and aging of the facility of project level based on the data. In particular, we compared and proposed models suitable for the use of big data by examining the validity of the state-based deterioration pattern and deterioration approximation model generated through machine learning algorithms of GP and SGP techniques. Result: As a result of reviewing the suitability of the proposed technique, it was considered that the RMSE and R2 in GP technique were 0.9854 and 0.0721, and the SGP technique was 0.7246 and 0.2518. Conclusion: This research through machine learning techniques is expected to play an important role in decision-making on investment in port facilities in the future if port facility data collection is continuously performed in the future.

The Current Status and Improvement Plan of Environmental Education Program in Relation to Climate Change in the Seoul Metropolitan Area (기후변화 관련 수도권 지역의 환경교육 프로그램 현황 및 개선방안)

  • Ryu, Hyeji;Song, Cholho;Lim, Chul-Hee;Kim, Sea Jin;Lee, Woo-Kyun
    • Journal of Climate Change Research
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    • v.7 no.2
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    • pp.169-176
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    • 2016
  • This study was to conduct a literature review and a theoretical study on 95 environmental education programs currently being run in the metropolitan area and obtained Environmental Education Program Certification of Ministry of Environment. First, the suitability of the environmental education programs was analyzed in terms of the following criteria which the Second National Environmental Education Master Plan propose: strengthening environmental education within the curriculum, strengthening preschooler environmental education, diversification of environmental education among targeted groups, and invigoration of community-based environmental education, and evaluated the contents and the proportion relevant to climate change. Based on the result, the measure for the improvement of the environmental education programs was proposed. As a result of the analysis, there were only 15 programs for children, and 20 programs for adults. Also, only 9% of the children and adult education programs were addressing climate change respectively, which was indicating low percentage. 75 programs were directly related to the school curriculum, and 8 programs were not related to subjects in regular curriculum. Also, considering addressing climate change, 7 out of 11 programs were related to the school curriculum. 71 out of 95 programs were located in the facilities of local governments. Programs that were including the contents relate to climate change were only 11 out of 95 programs. It is necessary to operate programs by expanding environmental education programs targeting children and adults, so all people are took into account, and consider the connectivity between curriculum and environmental education program in South Korea to increase the effectiveness of education. Also, it is necessary to educate people sustainably by relating the programs with various resources which can be utilized in the local community, to include climate change related contents with more proportion, and to address various subjects rather than focusing on one part of the subjects.

Research On Development of Usability Evaluation Contents and Weight of Importance for the Fire Detector Product (화재감지기 제품디자인 사용성 평가항목 개발 및 이해관계자 가중치평가 연구)

  • Jung, Ji-Yoon;Lee, Sang-Ki;Kim, Ji-Hyang;Yun, Su-Ji;Jang, Gi-Yong;Lee, Sung-Pil
    • The Journal of the Korea Contents Association
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    • v.19 no.1
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    • pp.404-412
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    • 2019
  • The purpose of this study is to develop the usability evaluation contents based on the needs of different stakeholder's related to the usability of the product, and to derive the design direction and apply it as the evaluation standard by applying the product design based on the results. I created a stakeholder map for a fire detector product and identified stakeholders related to usability. Based on 3 factors(Physical, cognitive, emotional) of the usability evaluation, I conducted survey on the building users and the building managers who have different requirements. There are 12 directions (ease of installation, durability, maintainability, additional functionality, effectiveness, attractiveness, visibility, consistency of information, environmental harmony, consistency, Image suitability, reliability). Through weighted analysis of three usability evaluation factors, I found factors were ranked in the same order of importance, but they were different in importance figure. Based on the results of the survey, overall product usability aspects were improved but effectiveness and environmental coordination aspects needed to be improved.