• Journal of Veterinary Science
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• 제23권2호
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• pp.21.1-21.7
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• 2022

Newcastle disease (ND), infectious laryngotracheitis (ILT) and avian metapneumovirus (aMPV) can be similar making it critical to quickly differentiate them. Herein, we adapted pre-existing molecular-based diagnostic assays for NDV and ILTV, and developed new assays for aMPV A and B, for use under synchronized thermocycling conditions. All assays performed equivalently with linearity over a 5 log₁₀ dynamic range, a reproducible (R² > 0.99) limit of detection of ≥ 10 target copies, and amplification efficiencies between 86.8%-98.2%. Using biological specimens for NDV and ILTV showed 100% specificity. Identical amplification conditions will simplify procedures for detection in diagnostic laboratories.

• 한국산업융합학회 논문집
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• 제23권4_2호
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• pp.583-591
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• 2020

Environmental problems have showen over the past decades due to the rapid development of the world economy and the continued growth of the population. Ocher has been widely used for water treatment research, but few studies have been conducted on adsorption of air pollutants using ocher and porous diatomite earth for indoor air purification. In this study, ocher and diatomite earth were sintered with filters to remove indoor air pollutants. The four types of TMA, H₂S, NH₃ and CH₃COOH were used to study the adsorption efficiency of ocher and porous diatomite filters. With the proper use of ocher, diatomite and copper catalysts, indoor air pollutants could be adsorbed. Alkaline substances (TMA and NH₃) and acidic substances (H₂S and CH₃COOH) were able to adsorb at 120 and 90 minutes, respectively.

• Smart Structures and Systems
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• 제29권5호
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• pp.677-691
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• 2022

Water cycle algorithm (WCA) has been a very effective optimization technique for complex engineering problems. This study employs the WCA for simultaneous prediction of heating load (L_H) and cooling load (L_C) in residential buildings. This algorithm is responsible for optimally tuning a neural network (NN). Utilizing 614 records, the behavior of the L_H and L_C is explored and the captured knowledge is then used to predict for 154 unanalyzed building conditions. Since the WCA is a population-based algorithm, different numbers of the searching agents were tested to find the most optimum configuration. It was observed that the best solution is discovered by 500 agents. A comparison with five newly-developed benchmark optimizers, namely equilibrium optimizer (EO), multi-tracker optimization algorithm (MTOA), slime mould algorithm (SMA), multi-verse optimizer (MVO), and electromagnetic field optimization (EFO) revealed that the WCANN predicts the desired parameters with considerably larger accuracy. Obtained root mean square errors (1.4866, 2.1296, 2.8279, 2.5727, 2.5337, and 2.3029 for the L_H and 2.1767, 2.6459, 3.1821, 2.9732, 2.9616, and 2.6890 for the L_C) indicated that the most reliable prediction was presented by the proposed model. The EFONN, however, provided a more time-effective solution. Lastly, an explicit predictive formula was elicited from the WCANN.

• 한국응용곤충학회지
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• 제61권4호
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• pp.549-554
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• 2022

곤충생태 분야에서 생명표와 관련된 연구는 곤충연구자들에게 많은 관심을 받는 주제중 하나이다. 보통 두 가지 방법으로 생명표 통계량중 내적자연증가율을 추정하고 있는데, 첫 번째 하나는 순증가율(R₀)에 자연로그를 취하고 평균세대기간(T)으로 나누어 근사치를 계산하는 방법이다(세대기간-기반 추정법). 다른 하나는 로트카-볼테라 개체군 생장 방정식에서 유도하여 최대우도법으로 정확한 내적자연증가율을 추정하는 방법이다(로트카-오일러식-기반 추정법). 후자의 경우 대상 집단의 초기 연령등급을 "0" 또는 "1"로 설정함에 따라 추정값에 차이가 발생하여 적용에 혼란이 제기되었다. 본 고찰에서는 생명표 통계량 계산과정의 역사를 간단히 정리하고, 로트카-오일러식-기반 추정법에서 최초 연령등급을 1로 설정한 경우 $\sum\limits_{x=1}^{w}e^{-rx}l_xm_x=1$의 형식, 반면 최초 연령등급을 0으로 설정한 경우 $\sum\limits_{x=0}^{w}e^{-r(x+1)}l_xm_x=1$의 형식을 적용해야 함을 재확인하였다.

• 생명과학회지
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• 제33권8호
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• pp.632-638
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• 2023

녹색종피와 자엽을 가진 녹색콩 품종 및 유전자원의 종실에는 눈 건강에 유익한 것으로 알려진 lutein 성분이 많이 함유되어져 있다. 그러나, 리폭시게나제, 쿠니츠 트립신 억제제(KTI), 렉틴 및 스타키오스와 같은 항영양 성분이 존재한다. 콩 식품 제조시 이러한 항영양 성분을 불활성화 시키기 위하여 고온 및 첨가제 처리가 필요하다. 따라서, 성숙 종실의 종피 및 자엽이 녹색이며 리폭시게나제, KTI 및 렉틴의 3가지 단백질이 모두 부재하면서 스타키오스의 함량이 매우 낮은 tetra null 유전자형(lox1lox2lox3tilers2)을 가진 계통을 선발하기 위하여 본 연구가 진행되었다. 다섯가지 유전자형을 이용한 육종집단으로부터 녹색종피 및 자엽을 가지면서 lectin 단백질이 없는 triple null 유전자형(lox1lox2lox3tile)을 가진 21개의 F₂ 종자가 선발되었다. DNA 마커를 이용하여 rs2rs2 유전자형을 가져 tetra null 유전자형인 4개의 F₂식물체가 선발되었으며 종자 형질이 양호한 한 개의 계통이 선발되었다. 선발계통의 F₆ 종자에서 리폭시게나제, KTI 및 렉틴 단백질의 부재가 확인되었다. 선발계통은 녹색종피, 녹색자엽 및 흰색배꼽을 가지고 있으며 백립중은 30.7 g 스타키오스의 함량은 2.40 g/kg으로 매우 낮았다. 선발계통은 리폭시게나제, KTI 및 렉틴의 3가지 단백질이 모두 없으며, 스타키오스의 함량이 낮은 유색콩 품종 개량을 위한 모본으로 활용될 수 있을 것으로 기대된다.

• Bulletin of the Korean Chemical Society
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• 제35권6호
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• pp.1706-1712
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• 2014

The OH($X^2{\Pi}$, ${\upsilon}^{\prime\prime}=0,1$) internal state distribution following the reaction of electronically excited oxygen atom ($O(^1D_2)$) with cyclo-$C_3H_6$ has been measured using laser-induced fluorescence, and compared with that following the reaction of $O(^1D_2)$ with $C_3H_8$. The overall characteristics of the OH internal energy distributions for both reactions were qualitatively similar. The population propensity of the ${\Pi}(A^{\prime})$ ${\Lambda}$-doublet sub-level suggested that both reactions proceeded via an insertion/elimination mechanism. Bimodal rotational population distributions supported the existence of two parallel mechanisms for OH production, i.e., statistical insertion and nonstatistical insertion. However, detailed analysis revealed that, despite the higher exoergicity of the reaction, the rotational distribution of the OH following the reaction of $O(^1D_2)$ with $C_3H_8$ was significantly cooler than that with cyclo-$C_3H_6$, especially in the vibrational ground state. This observation was interpreted as the effect of the flexibility of the insertion complex and faster intramolecular vibrational relaxation (IVR).

• 한국도서관정보학회지
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• 제6권
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• pp.105-140
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• 1979

This study is an attempt to present a model of the effective service area for branch library system planning in Dae Gu city as one of large urban public libraries in Korea. This model is built up through the analysis of the distribution of population and characteristics of community structure, based on the standard for the branch library system of a public library. The results are summarized as follows: 1. Under the circumstances of this country, each radius of the effective service area for branch libraries are as follows; $1{\sim}1.5km$. is adequate for the central library and major branches; 1km. for neighborhood branches; $0.5{\sim}0.8km$. for sub-branches. 2. Population within the radius of the effective service area of a given branch may range from 80,000 to 100,000 for major branches, from 50,000 to 60,000 for neighborhood branches, and from 20,000 to 30,000 for sub-branches. 3. The radius of the outer boundary for the effective service area may be between 4km. and 5km. from the heart of the city, and the inner boundary, 13.km. 4. Areas with the radius between 2km. and 3km. from the heart of the city may be selected as the most effective locations for branch libraries, and between 3km. and 4km. as the next priority. 5. The number of service areas may be 14, that is, 7 major branches(Sinam, Sinchun, Susung, Daemyung, Naedang, Dalsung, Rowon), 2 neighborhood branches (Pyungri, Nambu), and 5 sub-branches(Chimsan, Sangiuk, Bongduk, Hyomok, Dongchon)

• 한국동물학회:학술대회논문집
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• 한국동물학회 2000년도 공동 춘계학술대회
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• pp.88.1-88
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• 2000

No Abstract, See Full Text

• 약학회지
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• 제46권1호
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• pp.63-68
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• 2002

The purpose of this study was to estimate the population pharmacokinetics of clarithromycin in healthy adult Korean and to investigate the factors influencing the pharmacokinetics of clarithromycin. The population pharmacokinetic parameters of clarithromycin were calculated with the data from healthy adult Koreans. A total of 798 plasma concentrations obtained from 78 subjects after administration of a single oral dose of 250 mg or 500 mg were used for the modeling. The concentration-time data were fitted to a one-compartment open model assuming a first-order absorption and elimination with no lag time. The correlations between various factors [such as sex, age, height, weight, sect creatinine (Scr) and dose and pharmacokinetic parameters were estimated with stepwise linear recession analyses. The selected covariates were incorporated in the population model of NONMEM, and the importance of each covariate was investigated by means of backwards elimination. The apparent clearance (CL/F) was significantly correlated to Scr and sex, and the apparent volume of distribution (Vd/F) was significantly correlated to Scr and height in a nonlinear relationship. The population values of Ka was 1.8 h $r_{-1}$, CL/F was 37.71 L/hr, Vd/F was 200 L and t/ sub 1/2 / was 3.68 hrs for a male Korean with 170 m height and 1.0 mg/dL Scr.

• Imaging Science in Dentistry
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• 제53권1호
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• pp.77-82
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• 2023

Purpose: This study evaluated anatomical variations in the root canals of the lower premolars and molars in a Brazilian sub-population using cone-beam computed tomography (CBCT). Materials and Methods: In total, 121 CBCT images of patients were selected from a database. All images contained lower first and second premolars and molars on both sides of the arch, fully developed roots, and no treatment, resorption, or calcifications. In each image, the root canals of the lower premolars and molars were evaluated according to the Vertucci classification in On-Demand 3D software in the multiplanar reconstruction with dynamic navigation. Twenty-five percent of the images were re-assessed to analyze intraobserver confidence with the kappa test. Data were statistically evaluated with linear regression to evaluate the correlations of anatomic variations with age and sex, and the Wilcoxon test to analyze the laterality of variations, with a significance level of 5%. Results: The intraobserver agreement (0.94) was excellent. In general, the root canals of lower premolars and molars showed a higher prevalence of type I than other Vertucci classification types, followed by type V in premolars and type II in molars. When the molar roots were evaluated separately, type II was more frequent in mesial roots and type I in distal roots. Although age showed no correlations with the results, sex and laterality showed correlations with tooth 45 and the lower second premolars, respectively. Conclusion: The lower premolars and molars of a Brazilian sub-population showed a wide range of root canal anatomic variations.