• Journal of the Korean Magnetics Society
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• v.5 no.5
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• pp.358-361
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• 1995

We have investigated the quasi-two-dimensional magnetism for the layered transition metal compound (C/sub n/H/sub 2n+1/NH/sub 3/)/sub 2/CuCl/sub 4/ (n=10, 14) in the high temperature regions by means of EPR (Electron Paramagnetic Resonance) and SQUID measurements. As a result, the magnetic transitions were reflected in the EPR linewidths and the magnetic suceptibilities in a sensitive manner. Fluctuations of the magnetic susceptibility and a similar variation of the .DELTA. g =(g/sub .parallel. -/g/sub .perp. /)g/sub .parallel. / value were also observed around the structural phase transition temperatures.

• Journal of the Korean Society of Radiology
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• v.9 no.4
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• pp.213-217
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• 2015

To report problems found in a patient who has implemented stent implantation and then conducted a perfusion MRI using ASL(Arterial Spin Labeling), in order to suggest a solution to them. The perfusion MRI was conducted, using pCASL among ASL methods. Data from pCASL(Pseudo Continuous Arterial Spin Labeling) was acquired together with the structural image simply by changing position(labeling gap 15 mm, 170 mm) of the labeling pulse to avoid stent. Data was processed through the ASLtbx. When perfusion MRI was acquired using pCASL, it showed that the position of the conventional labeling pulse (labeling gap 24 mm) was overlapped with that of stent, which made signal intensity in right brain tissue appear as if it were void. When the labeling pulse was positioned (labeling gap 15 mm) to avoid stent, high signal intensity images were acquired. In labeling pulse (labeling gap 170 mm), the signal intensity was more reduced due to relaxation before labeled blood arrived at the imaging slice. pCASL can be stably repeated measurements because it does not use a contrast agent. And it should be selected with the appropriate image acquisition parameters for the high quality image.

• Journal of the Korean earth science society
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• v.23 no.1
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• pp.87-96
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• 2002

Aeromagnetic and gravity data were analyzed to delineate the subsurface structure of the Yeongdong basin and its related fault movement in the Okcheon fold belt. The aeromagnetic data of the total intensity (KIGAM, 1983) were reduced to the pole and three dimensional inverse modeling, which considers topography of the survey area in the modeling process, were carried out. The apparent susceptibility map obtained by three dimensional magnetic inversion, as well as the observed aeromagnetic anomaly itself, show clearly the gross structural trend of the Yeongdong basin in the direction on between $N30^{\circ}E$ and $N45^{\circ}E$. Gravity survey was carried out along the profile, of which the length is about 18.2 km across the basin. Maximum relative Bouguer anomaly is about 7 mgals. Both forward and inverse modeling were also carried out for gravity analysis. The magnetic and gravity results show that the Yeongdong basin is developed by the force which had created the NE-SW trending the magnetic anomalies. The susceptibility contrast around Yeongdong fault is apparent, and the southeastern boundary of the basin is clearly defined. The basement depth of the basin appears to be about 1.1 km beneath the sea level, and the width of the basin is estimated to be 7 km based on the simultaneous analysis of gravity and magnetic profiles. There exists an unconformity between the sedimentary rocks and the gneiss at the southeastern boundary, which is the Yeongdong fault, and granodiorite is intruded at the northwestern boundary of the basin. Our results of gravity and magnetic data analysis support that the Yeongdong basin is a pull-apart basin formed by the left-stepping sinistral strike-slip fault, which formed the Okcheon fold belt.

• Korean Journal of Metals and Materials
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• v.50 no.5
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• pp.401-406
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• 2012

When viewed using a magnetic resonance imaging (MRI) system, invasive materials inside the human body, in many cases, severely distort the MR image of human tissues. The degree of the MR image distortion increases in proportion not only to the difference in the susceptibility between the invasive material and the human tissue, but also to the intensity of the magnetic field induced by the MRI system. In this study, by blending paramagnetic Ti particles with diamagnetic graphite, we synthesized $Ti_{100-x}C_x$ composites that can reduce the artifact in the MR image under the high-strength magnetic field. Of the developed composites, $Ti_{70}C_{30}$ showed the magnetic susceptibility of ${\chi}=67.6{\times}10^{-6}$, which corresponds to 30% of those of commercially available Ti alloys, the lowest reported in the literature. The level of the MR image distortion in the vicinity of the $Ti_{70}C_{30}$ composite insert was nearly negligible even under the high magnetic field of 4.7 T. In this paper, we reported on a methodology of designing new structural materials for bio-applications, their synthesis, experimental confirmation and measurement of MR images.

• Coupled systems mechanics
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• v.9 no.4
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• pp.359-379
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• 2020

Due to susceptibility of bridges in the past earthquakes, vulnerability assessment and strengthening of bridges has gained a particular significance. The objective of the present study is to employ an analytical method for the development of fragility curves, as well as to investigate the effect of strengthening on the RC box-girder bridges. Since fragility curves are used for pre-and post-earthquake planning, this paper has attempted to adopt the most reliable modeling assumptions in order to increase the reliability. Furthermore, to acknowledge the interaction of soil, abutment and pile, the effect of different strengthening methods, such as using steel jacketing and FRP layers, the effect of increase in the bridge pier diameter, and the effect of vertical component of earthquake on the vulnerability of bridges in this study, a three-span RC box-girder bridge was modeled in 9 different cases. Nonlinear dynamic analyses were carried out on the studied bridges subjected to 100 ground motion records via OpenSEES platform. Therefore, the fragility curves were plotted and compared in the four damage states. The results revealed that once the interaction of soil and abutment and the vertical component of the earthquake are accounted for in the calculations, the median fragility is reduced, implying that the bridge becomes more vulnerable. It was also confirmed that steel jackets and FRP layers are suitable methods for pier strengthening which reduces the vulnerability of the bridge.

• Journal of the Korean Ceramic Society
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• v.33 no.5
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• pp.507-513
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• 1996

Nonlinear optical properties of TeO2-PbO-GeO2 glasses were investigated and their correlation with struc-tural modification was investigated. Third-order nonlinear susceptibility $\chi$, ranged between 5.0$\times$10-13 esu and 10.7$\times$10-13 esu which are approximately 20-40 times larger than that of silica glass. The glass with a composition of 85(80TeO2-20PbO)-15GeO2(mol%) seemed to provide an optimum compromise between $\chi$and the stability against crystallization. Analyses of the Raman spectra suggested that these glasses are mainly composed of [TeO4] tbp, [TeO3]tp and [GeO4] tetrahedral structural units. It was concluded that the positive contribution of Pb2+ with high polarizability to $\chi$ in TeO2-PbO glasses overwhelmed the negative influence due to the structural modification of [TeO4]tbplongrightarrow[TeO3]tp. On the other hand addition of GeO2 in TeO2-PbO-GeO2 glasses resulted in the decrease of $\chi$ values. This behavior was attributed to the formation of [GeO4] polyhedra at the expense of [TeOn] polyhedra and Pb2+ ions which normally sowed a higher contribu-tion to $\chi$ than [GeO4] polyhedra.

• Genomics & Informatics
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• v.8 no.3
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• pp.150-158
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• 2010

Genome-wise association studies (GWASs) have become popular approaches to identify genetic variants associated with human biological traits. In this study, we applied Structural Equation Models (SEMs) in order to model complex relationships between genetic networks and traits as risk factors. SEMs allow us to achieve a better understanding of biological mechanisms through identifying greater numbers of genes and pathways that are associated with a set of traits and the relationship among them. For efficient SEM analysis for GWASs, we developed a procedure, comprised of four stages. In the first stage, we conducted single-SNP analysis using regression models, where age, sex, and recruited area were included as adjusting covariates. In the second stage, Fisher's combination test was conducted for each gene to detect significant genes using p-values obtained from the single-SNP analysis. In the third stage, Fisher's exact test was adopted to determine which biological pathways were enriched with significant SNPs. Finally, based on a pathway that was associated with the four traits in common, a SEM was fit to model a causal relationship among the genetic factors and traits. We applied our SEM model to GWAS data with four central obesity related traits: suprailiac and subscapular measures for upper body fat, BMI, and hypertension. Study subjects were collected from two Korean cohort regions. After quality control, 327,872 SNPs for 8842 individuals were included in the analysis. After comparing two SEMs, we concluded that suprailiac and subscapular measures may indirectly affect hypertension susceptibility by influencing BMI. In conclusion, our analysis demonstrates that SEMs provide a better understanding of biological mechanisms by identifying greater numbers of genes and pathways.

• Journal of Conservation Science
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• v.31 no.3
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• pp.227-241
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• 2015

Fungi were isolated from mural painting in tomb no.6 at songsan-ri, Gong-ju. Antifungal susceptibility of essential oils extracted from natural medicine was tested and it confirmed applicability for mural painting in tombs. 26 species of fungi collected from air-borne and wall surfaces were identified to 15 species of Ascomycetes, 2 species of Zygomycetes, 1 of Basidiomycetes. Wheat starch and gelatin degradability were evaluated as isolated fungi. SY-18, SY-23, SY-25 showed high degradability of wheat starch. SY-18, SY-21, SY-23 were decomposed into gelatin. Biochemical characteristics of decomposing fungi to wheat starch glue and cowhide glue were analyzed by using ${\alpha}-amylase$ and gelatinase activity. An Antifungal test was conducted in Anethole and Eugenol. Anethole and Eugenol mixture(1:2) showed high antifungal susceptibility. Natural adhesives help microbial growth and can cause structural damage in mural painting. The expectation of this study is the possibility to control microbial growth in wall painting using natural essential oils. It can be used as a data for conservation method to control microbial damages.

• Journal of the Korean GEO-environmental Society
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• v.20 no.1
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• pp.67-74
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• 2019

Frost heave is one of the representative engineering characteristics in cold regions. In South Korea, which is located in seasonal frost area, structural damage caused by frost heave and thaw happens and the need for research on the frost heave is increasing. In this paper, newly developed transparent temperature-controllable cell is used to focus on the frost heave. Frost susceptible artificial soil is used to analyze water intake rate which is one of the important factors in frost susceptibility criteria. Frost heave rate and water intake rate have similar behavior after heave by freezing of pore water converges. O-ring installed in the upper pedestal to measure water intake rate generates side friction between the inner wall of the freezing cell and O-ring, thereby hindering frost heave. Therefore, the frost susceptibility criteria using the water intake rate is not reliable. It is appropriate to use frost heave rate which has similar behavior with water intake rate. Frost heave tests were performed under two different specimen heights. Overburden pressure, temperature gradient and dry unit weight were set under similar state. Based on laboratory testing results, frost heave is independent on the specimen height.

• The Journal of Korean Medicine
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• v.45 no.1
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• pp.150-164
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• 2024

Objectives: This study aimed to investigate the levels of brain iron deposition in Parkinson's disease (PD) patients using Quantitative Susceptibility Mapping (QSM) and to determine whether distinctions compared to the general population exist. Furthermore, we examined potential variations in iron deposition among different PD subtypes. Methods: Structural brain imaging was conducted on 75 participants at Gangdong Kyung Hee University Hospital between August 2017 and May 2020. PD patients were categorized into Tremor Dominant (TD) and Postural Instability and Gait Difficulty (PIGD) subtypes. Voxel-based morphometry and QSM were employed to compare voxel-wise magnetic susceptibility across the entire brain between Normal Controls (NC) and PD groups. Subsequently, QSM values were compared between TD and PIGD groups. Results: QSM values were compared among 46 PD patients and 23 normal controls, as well as between TD (n=22) and PIGD (n=24) groups. Voxel-based QSM analysis revealed no significant differences between groups. Similarly, ROI-based QSM analysis showed no significant distinctions. Conclusions: No significant variations were observed between the PD patient group, NC group, or PD subtypes. This study systematically compared QSM values across a broad range of brain regions potentially linked to PD pathology. Additionally, the subdivision of the PD group into TD and PIGD subtypes for QSM-based iron deposition analysis represents a meaningful and innovative approach.