• BMB Reports
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• 제45권6호
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• pp.323-330
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• 2012

The glycome consists of all glycans (or carbohydrates) within a biological system, and modulates a wide range of important biological activities, from protein folding to cellular communications. The mining of the glycome for disease markers represents a new paradigm for biomarker discovery; however, this effort is severely complicated by the vast complexity and structural diversity of glycans. This review summarizes recent developments in analytical technology and methodology as applied to the fields of glycomics and glycoproteomics. Mass spectrometric strategies for glycan compositional profiling are described, as are potential refinements which allow structure-specific profiling. Analytical methods that can discern protein glycosylation at a specific site of modification are also discussed in detail. Biomarker discovery applications are shown at each level of analysis, highlighting the key role that glycoscience can play in helping scientists understand disease biology.

• 한국보육지원학회지
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• 제16권2호
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• pp.47-65
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• 2020

Objective: This study investigated the relationship between preschool teachers' creativity, teaching efficacy, and creativity-fostering teaching and examined the mediating effect of teaching efficacy. Methods: A total of 202 preschool teachers participated in this study. The Creative Behavior Inventory (CBI), Teaching Efficacy Scale, and the Creativity-Fostering Teacher Behavior Index (CFTI) were used for the survey. A hypothesized model and alternative model were tested using structural equation modeling. Collected data were analyzed using 18.0 PSAW and AMOS. Results: The results showed that preschool teachers' creativity was positively associated with their teaching efficacy and creativity fostering teaching. Preschool teacher's teaching efficacy positively related to their creativity fostering teaching. Preschool teachers' creativity had a significant positive direct effect on creativity-fostering teaching and also an indirect effect on creativity-fostering teaching via teaching efficacy. Conclusion/Implications: Implications to foster creativity in preschool and kindergarten are discussed, highlighting the necessity for teacher education to promote teaching efficacy as well as teacher's creativity and creativity-related activities.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 1996년도 International Conference on Agricultural Machinery Engineering Proceedings
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• pp.238-246
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• 1996

When the important structures or components of agricultural machinery are designed, the full-filed methods of stress analysis can provide enough information in order to obtain lighter weight and prevent failure. The photoelasticity has been applicated to solve many practical engineering problems. The coating method provides full-field information, enabling the engineers to determine the complete distribution of surface strains and directly highlighting severely strained areas, especially for the welded frames of agricultural machinery. A combined method of model and prototype for strain analysis of excavator has been successfully applied to improve design. A measuring and recording system controlled by micro-computer and application software for dynamic event was studied. It can be widely used in structural failure analysis under cyclical loading . Typical application concerned stress field of crack tip and failure analysis of some mechanical structures are introduced are in roduced briefly in this paper.

• East Asian Economic Review
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• 제24권4호
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• pp.389-416
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• 2020

This paper provides empirical evidence on the reorganization of GVCs in East Asia, highlighting that structural trends explain a decrease in the fragmentation of production after 2011 but that it is not the result of rising trade costs along the value chain. Using harmonized inter-country input-output tables, the paper first analyzes the global import intensity of production to document changes in the structure of GVCs. It then calculates theory-consistent bilateral trade costs for intermediate and final products using an approach derived from the gravity literature and introduces a new index of cumulative trade costs along the value chain. These data are used to discuss whether the decrease in global imports is the consequence of shifts in demand, efficiency-enhancing strategies of firms or rising trade costs. Between 2011 and 2016, cumulative trade costs have decreased in East Asian GVCs. However, as COVID-19 is likely to intensify trade and investment uncertainties, trade costs could increase in the future. Policies aimed at reducing uncertainties and preserving the gains from trade and investment liberalization will be key in this new environment.

• 대한족부족관절학회지
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• 제27권4호
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• pp.117-122
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• 2023

Collagen is the most common structural protein in the connective tissues of vertebrates, playing a crucial role in maintaining the tissue structure and wound healing. Atelocollagen retains the original properties of collagen but does not induce inflammatory cytokines. Atelocollagen is extracted from various animals and humans, with bovine-derived collagen being the most commonly used. The safety and efficacy of atelocollagen have been demonstrated through multiple studies, but further research will be needed in the field of orthopedics regarding its range of use and effects. Foot and ankle diseases have attracted little research attention, highlighting the need for further studies.

• 한국전산구조공학회논문집
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• 제34권5호
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• pp.319-325
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• 2021

후쿠시마 원전사고 발생으로 다수기의 지진안전성에 관한 연구의 필요성이 부각되었다. 한 부지에 건설된 원자력발전소의 경우 유사한 지진응답을 보이기 때문에 적게나마 원자력발전소 SSCs간의 지진손상에 대하여 상관성이 존재하므로 합리적 지진안전성 평가를 위하여 지진손상 상관성을 고려하여야 한다. 본 연구에서는 쌍둥이 호기의 필수전원상실사건에 대하여 확률론적 지진안전성 평가를 수행하였다. 적절한 지진손상 상관계수를 도출하기 위하여 확률론적 지진응답해석을 수행하여 적용하였다. External Event Mensuration System 프로그램을 활용하여 다수기의 필수전원상실사건의 고장수목을 구성하여 지진취약도 및 지진리스크를 분석하였다. 또한 SSCs간의 지진손상 상관성을 완전독립 및 완전종속으로 고려하여 비교 분석을 수행하였다.

• 복식문화연구
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• 제28권4호
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• pp.409-419
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• 2020

Building on Technology Readiness and Acceptance Model(TRAM), the study aimed to examine how technology readiness affects consumers' perceptions of ease of use, usefulness, and risk, which in turn predict their intention to use retail service robots. Specifically, the study proposed that technology readiness motivators (optimism and innovativeness) would influence perceived ease of use and usefulness, while technology readiness inhibitors (discomfort and insecurity) would affect perceived risk. The study further examined if the perception factors (ease of use, usefulness, and risk) contribute to intention to use retail service robots. A survey method was used with data collected from Korean consumers. The final sample size was 418. The data was analyzed using structural equation modeling. Findings of the study revealed that technology readiness motivators positively affected perceived ease of use and usefulness while innovativeness had no impact on usefulness. All the inhibitors increased perceived risk. Lastly, as hypothesized, perceptions of ease of use, usefulness, and risk predicted intention to use retail service robots. This study extended the retail technology literature by applying and validating TRAM to the context of consumer acceptance of retail service robots. The study further helped marketers and retailers by highlighting the importance of technology readiness in improving consumer perceptions and responses towards retail service robots.

• 유통과학연구
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• 제15권4호
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• pp.15-23
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• 2017

Purpose - This research aims to determine whether the consumer affinity and ethnocentrism as well as the image of a foreign country (Japanese product as the most popular product in Indonesia) are able to influence behavior related to the perceived risk and willingness to buy foreign products from the affinity country. Research design, data, and methodology - Using survey techniques with 164 respondents, the study uses structural equation model with confirmatory factor analysis (CFA). To ensure the research objective and appropriate respondent, then we select an individual who have interest on Japanese culture & language. The primary and secondary data used in this study. Primary data refers to information collected directly from respondent by questionnaires dissemination while secondary data is provided from well-established literatures. Results - The results show us that the ethnocentrism has dominant affection role compared to affinity in order to influence consumer behavior meanwhile, the product country image has cognition role to evoke consumer desire to consume foreign products. Conclusions - From a theoretical perspective, the study contributes to international marketing literature by refining the conceptualization of the consumer affinity construct and highlighting its multidimensional nature. The consumer affinity research need to enrich in term of the context and the different culture and situation.

• 유통과학연구
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• 제17권5호
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• pp.73-83
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• 2019

Purpose - The purpose of this research is twofold; first, it attempts to categories customer demands into challenging and hindrance stressors, second, it investigates the effect of customer challenging stressors, hindrance stressors and customer resources on job satisfaction, emotional exhaustion and turnover intention of frontline employees. Research design, data, and methodology - A quantitative research method with an online survey was adopted to test the proposed hypotheses. Sample was collected from 186 frontline employees. And, structural equation model was conducted through AMOS 20.0 to verify the proposed hypotheses. Results - First, customer challenging stressors and customer resources positively affect job satisfaction. Second, customer hindrance stressors negatively affect job satisfaction and positively affect emotional exhaustion. Finally, job satisfaction negatively affects turnover intention whereas emotional exhaustion positively affects turnover intention of frontline employees. Contributions - In term of theoretical contributions, the current study categorized the customer demands into challenging and hindrance stressors and empirically tested the effect of challenging and hindrance stressors on emotional exhaustion, job satisfaction and turnover intention of frontline employees. Managerially, this study provides insights to the firm by highlighting the presence of challenging stressors and customer resources which have positive effect on the attitudes and behaviors of the frontline employees.

• Structural Engineering and Mechanics
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• 제55권1호
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• pp.161-189
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• 2015

Soil-pile raft-structure interaction is recognized as a significant phenomenon which influences the seismic behaviour of structures. Soil structure interaction (SSI) has been extensively used to analyze the response of superstructure and piled raft through various modelling and analysis techniques. Major drawback of previous study is that overall interaction among entire soil-pile raft-superstructure system considering highlighting the change in design forces of various components in structure has not been explicitly addressed. A recent study addressed this issue in a broad sense, exhibiting the possibility of increase in pile shear due to SSI. However, in this context, relative stiffness of raft and that of pile with respect to soil and length of pile plays an important role in regulating this effect. In this paper, effect of relative stiffness of piled raft and soil along with other parameters is studied using a simplified model incorporating pile-soil raft and superstructure interaction in very soft, soft and moderately stiff soil. It is observed that pile head shear may significantly increase if the relative stiffness of raft and pile increases and furthermore stiffer pile group has a stronger effect. Outcome of this study may provide insight towards the rational seismic design of piles.