• International Journal of Industrial Entomology and Biomaterials
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• 제19권1호
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• pp.181-185
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• 2009

In this paper, the regenerated silk fibroin (SF)/hydroxypropyl methylcellulose (HPMC) blend filaments were prepared by wet spinning and the effect of HPMC concentration on the post drawing and morphology of blend filaments was elucidated. The result of maximum draw ratio indicated that the wet spinnability of wet spun SF / HPMC was improved with increasing HPMC concentration until 8% and remained constant after that concentration. The SEM observation revealed that the enhanced wet spinnability of blend filaments was strongly related to the morphological change by increasing HPMC concentration. Regardless of HPMC concentration, as SF content was reduced, the wet spinnability of blend film decreased resulting in reduced maximum draw ratio. It was also found by SEM observation that the cross section of blend filament deviated from circularity with an increase of HPMC content.

• 가족자원경영과 정책
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• 제10권1호
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• pp.67-81
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• 2006

This study focused on the system regarding leave of absence in relation to family welfare, which has become a routine in some western countries, in three different perspectives. Those were the relations between reduced working hours and quality of life, maternal recreation, and finally, relations between infrastructure of vacation and culture. Systematic settlement of reduced working hours and maternal recreation in Germany allowed more time among family members and made large contribution to the improvement of family welfare in general. Since the stability of society is strongly based on the stability of family, Germany deserved to be case-studied as a good model. The recent tendency shows that Korean workers are starting to spend more time with their own family members than with their colleagues, and, as seen in the case of Germany, the stability of family welfare will improve if various infrastructures for family leisure are properly established in Korea.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.382-384
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• 2002

Filtered-Back-Projection technique is used in X-ray CT image reconstruction. This requires X-ray transmission data from all directions. As the transverse cross-section of the body is approximately 50 cm, transmitted X-rays in this direction are strongly attenuated. If X-ray transmission data in this direction is avoided, exposure to the patients seems to be reduced one 20th of usual value. Some alternative method has to be found for clinically sufficient image quality. New methods are under development and tentative results are reported that utilizes the principle of superposition.

• Molecules and Cells
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• 제39권2호
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• pp.136-140
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• 2016

Eph receptors and their ligands, ephrins, mediate cell-to-cell contacts in a specific brain region and their bidirectional signaling is implicated in the regulation of apoptosis during early brain development. In this report, we used the alpha(${\alpha}$)-Cre transgenic line to induce ephrin-A5 over-expression in the distal region of the neural retina. Using this double transgenic embryo, we show that the over-expression of ephrin-A5 was responsible for inducing massive apoptosis in both the nasal and temporal retinas. In addition, the number of differentiated retinal neurons with the exception of the bipolar neuron was significantly reduced, whereas the laminar organization of the mature retina remained intact. Consistent with this finding, an analysis of the mature retina revealed that the size of the whole retina-particularly the nasal and temporal regions-is markedly reduced. These results strongly suggest that the level of ephrin-A5 expression plays a role in the regulation of the size of the retinal progenitor pool in the neural retina.

• 한국연초학회지
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• 제24권1호
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• pp.7-12
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• 2002

During the screening or antiviral substances having inhibitory effect on tobacco mosaic virus(TMV) infection to tobacco plants, we found that a bacterial isolate, KTB61, which was identified as a Pseudomonas sp., strongly inhibited the formation of TMV local lesions. When the culture filtrate from KTB61 was applied on the upper surface of leaves of N. tabaccum Xanthi-nc tobacco at the same time of or 24 hours before TMV inoculation, almost complete inhibition was achieved. Incidence of systemic TMV infection to the susceptible tobacco cultivar, NC82, was reduced by 95% when TMV was inoculated onto the upper surface of leaves 24 hours after spraying the culture filtrate. Also 75∼80% of inhibitory effect was obtained by the inoculation of TMV onto the under surface of the leaves treated with culture filtrate 24 hours beforehand. In field trials, the TMV infection was reduced by 96.5% when the tobacco seedlings, N. tabaccum cv. NC82, were soaked with culture filtrate before transplanting.

• 한국자동차공학회논문집
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• 제10권2호
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• pp.15-22
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• 2002

Lately, our world is faced with very serious problems related to the increased air pollution of the exhaust emissions from automobiles. In particular, the exhaust emissions of diesel engines are recognized as a main cause which strongly influence environment. Lots of researchers have attempted to develop various alternative fuels to reduce these harmful emissions in diesel engine. The purpose of this investigation is to evaluate the possibility of esterfied rice bran oil for diesel fuel substitution in a naturally aspirated D. 1. diesel engine, and also find means to reduce smoke emissions in esterfied rice bran oil combustion. The smoke emission of esterfied rice bran oil is reduced remarkably in comparison with commercial gas oil, that is, it was reduced approximately 58.2% at 2500rpm. But, power, torque and brake specific energy consumption didn't have no large differences. It was concluded that esterfied rice bran oil can utilize effectively as an alternative and renew- able fuel fur diesel engine.

• 대한기계학회논문집B
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• 제32권12호
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• pp.945-953
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• 2008

Laminar film condensation of saturated vapor in forced flow over a flat plate is analysed. The problem is formulated as exact boundary-layer solution and integral approximate solution. From numerical solutions of the governing equations, it is found that the energy transfer by convection and the effect of inertia term in the momentum equation in negligibly small for low pressure but quite important for high pressure. The condensate rate, liquid-vapor interfacial shear stress and local heat transfer are strongly dependent on the reduced pressure $P_r$ and the modified Jacob number Ja/Pr.

• 한국환경보건학회지
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• 제10권2호
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• pp.89-97
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• 1984

The possible effects of garlic (Aliium sativurn L.) extract on growth and aflatoxin production by Aspergillus parasiticus R- 716 were investigated. Various solvent extracts of garlic strongly inhibited growth and sporulation by Aspergillus parasiticus R-716, and effective solvents used for extraction of garlic were chloroform, benzene, and water-chloroform. The growth and aflatoxin production decreased with the increase in extract concentration, and extract equivalent 1.5g of raw garlic weight in 25ml SLS medium completely inhibited, and at a level of 1.25g garlic, total aflatoxin was reduced 64% (472 ${\mu}g$/25ml) of that produced in the control (1, 352 ${\mu}g$/25 ml). During cultivation inhibitory rate of growth was reduced from 89.1% to 40% and aflatoxin $B_2$, $G_1$ production increased with the laps of time. Especially garlic extract appeared to have a stimulatory effect on lipid accumulation on the contrary aflatoxin production.

• Biomolecules & Therapeutics
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• 제27권2호
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• pp.145-151
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• 2019

Methamphetamine (METH) acts strongly on the nervous system and damages neurons and is known to cause neurodegenerative diseases such as Alzheimer's and Parkinson's. Flavonoids, polyphenolic compounds present in green tea, red wine and several fruits exhibit antioxidant properties that protect neurons from oxidative damage and promote neuronal survival. Especially, epicatechin (EC) is a powerful flavonoid with antibacterial, antiviral, antitumor and antimutagenic effects as well as antioxidant effects. We therefore investigated whether EC could prevent METH-induced neurotoxicity using HT22 hippocampal neuronal cells. EC reduced METH-induced cell death of HT22 cells. In addition, we observed that EC abrogated the activation of ERK, p38 and inhibited the expression of CHOP and DR4. EC also reduced METH-induced ROS accumulation and MMP. These results suggest that EC may protect HT22 hippocampal neurons against METH-induced cell death by reducing ER stress and mitochondrial damage.

• Childhood Kidney Diseases
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• 제21권1호
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• pp.1-7
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• 2017

Mitogen-activated protein kinases (MAPKs) play important roles in various cellular functions including proliferation, differentiation, and apoptosis. We showed that MAPKs are developmentally regulated in the rat kidney. p38 MAPK (p38) and extracellular signal-regulated kinase (ERK) were strongly expressed in the fetal kidney, whereas c-Jun N-terminal kinase (JNK) was detected predominantly in the adult kidney. The inhibition of p38 or ERK in organ culture resulted in reduced nephron formation with or without reduced kidney size. On the other hand, persistent fetal expression pattern of MAPKs, i.e., upregulation of p38 and ERK and downregulation of JNK, was observed in the cyst epithelium of human renal dysplasia, ovine fetal obstructive uropathy, and pcy mice, a model of polycystic kidney disease. Furthermore, activated p38 and ERK induced by cyclic stretch mediated proliferation and $TGF-{\beta}1$ expression in ureteric bud cells, probably leading to cyst formation and dysplastic changes. Inhibition of ERK slowed the disease progression in pcy mice. Finally, ERK and p38 were inactivated in the early embryonic kidney subjected to maternal nutrient restriction, characterized by reduced ureteric branching and nephron number. Thus, MAPKs mediate the development of normal and diseased kidney. Their modulation may result in novel therapeutic strategies against developmental abnormalities of the kidney.