• Journal of Preventive Medicine and Public Health
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• 제43권3호
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• pp.279-282
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• 2010

Objectives: This study investigates whether Korean news media pay more attention to emerging diseases than chronic ones, and whether they closely follow the changes in the magnitude of health risks of chronic or well-known diseases. These two features are expected to appear as the result of surveillance function served by health journalism that should be the main source of the public's risk perception. Methods: The number of stories published in 10 newspapers containing the words, 'SARS,' 'Bovine Spongiform Encephalopathy,' 'Avian Influenza,' and 'Influenza A virus' was compared with the number of stories on chronic or wellknown diseases. We also counted the annual number of stories, published in a 12-year period, containing following terms: 'cancer,' 'diabetes,' 'hypertension,' 'pneumonia,' and 'tuberculosis.' The number was compared with the actual mortality of each disease. Results: Although cancer represented the primary cause of mortality, the newspapers covered key emerging diseases more than cancer or other well-known diseases. Also, media coverage of 'pneumonia' and 'tuberculosis' did not vary in accordance with changes in the mortality of each disease. However, the news media coverage did vary in accordance with the mortality of 'cancer,' 'diabetes,' and 'hypertension.' Conclusions: Korean health journalism was found to have both strong and weak points. The news media reduced the relative level of attention given to pneumonia and tuberculosis. Bearing in mind the major influence of news coverage on risk perception, health professionals need to be more proactive about helping to improve Korean health journalism.

• Molecules and Cells
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• 제42권11호
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• pp.739-746
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• 2019

Significant knowledge about the pathophysiology of Alzheimer's disease (AD) has been gained in the last century; however, the understanding of its causes of onset remains limited. Late-onset AD is observed in about 95% of patients, and APOE4-encoding apolipoprotein E4 (ApoE4) is strongly associated with these cases. As an apolipoprotein, the function of ApoE in brain cholesterol transport has been extensively studied and widely appreciated. Development of new technologies such as human-induced pluripotent stem cells (hiPSCs) and CRISPR-Cas9 genome editing tools have enabled us to develop human brain model systems in vitro and readily manipulate genomic information. In the context of these advances, recent studies provide strong evidence that abnormal cholesterol metabolism by ApoE4 could be linked to AD-associated pathology. In this review, we discuss novel discoveries in brain cholesterol dysregulation by ApoE4. We further elaborate cell type-specific roles in cholesterol regulation of four major brain cell types, neurons, astrocytes, microglia, and oligodendrocytes, and how its dysregulation can be linked to AD pathology.

• Nuclear Engineering and Technology
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• 제54권11호
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• pp.4359-4372
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• 2022

Turbulent mixing in buoyant flows is an essential mechanism involved in many scenarios related to nuclear safety in nuclear power plants. Comprehensive understanding and accurate predictions of turbulent buoyant flows in the reactor are of crucial importance, due to the function of mitigating the potential detrimental consequences during postulated accidents. The present study uses URANS methodology to investigate the buoyancy-influenced flows in the reactor pressure vessel under the main steam line break accident scenarios. With a particular focus on the influence of turbulent heat flux closure models, various combinations of two turbulence models and three turbulent heat flux models are utilized for the numerical simulations of three ROCOM tests which have different characteristic features in terms of the flow rate and fluid density difference between loops. The simulation results are compared with experimental measurements of the so-called mixing scalar in the downcomer and at the core inlet. The study shows that the anisotropic turbulent heat flux models are able to improve the accuracy of the predictions under conditions of strong buoyancy whilst in the weak buoyancy case, a major role is played by the selected turbulence models with essentially a negligible influence of the turbulent heat flux closure models.

• Steel and Composite Structures
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• 제47권4호
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• pp.467-488
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• 2023

Seismic retrofit of an existing steel-reinforced concrete hospital building that features innovative use of a continuous energy-dissipative steel column (CEDC) system is presented in this paper. The special system has been adopted to provide an efficient solution taking into account the difficulties of applying traditional intervention techniques to minimize the impact on architectural functionality and avoid the loss of building function and evacuation during the retrofit implementation. The lateral stiffness and strength of the CEDC system were defined based on the geometric and mechanical properties of the steel strip dampers. The hysteretic behavior under cyclic loadings was defined using a simplified numerical model. Its effectiveness was validated by comparing the results of full-scale experimental data available from the literature. All the main design considerations of the retrofitting plan are described in detail. The effectiveness of the proposed retrofitting system was demonstrated by nonlinear time-history analyses under different sets of earthquake-strong ground motions. The analysis results show that the CEDC system is effective in controlling the deformation pattern and significantly reducing damage to the existing structure during major earthquakes.

• 건축역사연구
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• 제11권3호
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• pp.21-34
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• 2002

This study is to analyse the transformation process of spatial structure of traditional small city structure in Jeollabuk-Do in the process of modern urbanization between 19th century and the year 2000. The small cities, IM-PI, YONG-AN, YEO-SAN, OK-GOO, GO-SAN, MU-JANG, GUM-MA, GO-BU, which have been local administrative center in CHO-SUN dynasty, have role of local administrative center of subdivision of country-myon, except OK-GOO. The method of this study is to investigate the transformation process of spatial structural elements of with the actual field surveys, the analysis of Gunhyun map made in 1872, land registration maps in 1910s and 2000, and various topological maps. The elements of analysis are the topological site and geographical situation conditions, the urbanized areas, the street systems, the function of streets, the focal points of urban land use, the land use systems, and the location of major facilities such as administration facilities, markets, bus terminals. The analytical point of view and the results are as follows. There is strong relationship between the transformation of internal matrix route system and the growth pattern of urbanized areas, Especially on the contrary to the matrix route with East-West direction which has the role of checking the growth of urbanized area, the South-North direction route acts as the leading line of the growth. The focal points structure of urban land use shows transformation process from the point of central space of administrative district in front of Nae-A, to the access point to administrative district or to the access point to housing and neighborhood commercial area. From the point of functional area structure and major facilities location, line-type commercial area is developed along the line of central axis route and access route to administrative district. Especially direction of the growth of commercial area is strongly connected with the interrelationship between the study area and its neighboring cities. Pattern of commercial district development is varied with the direction of matrix route. That is, commercial district, which shows one side development pattern along the East-West direction route, is developed on both sides of street along the South-North direction route.

• 대한치과보철학회지
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• 제44권1호
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• pp.73-84
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• 2006

The importance of soft tissue response to implant abutments has become one of the major issues in current implant dentistry. To date, numerous studies have emphasized on maintaining connective tissue barriers in quantity, as well as in quality fir the long term success of dental implants. The cells mainly consisting the soft tissue around dental implants are fibroblasts and epithelial cells. The mechanism of the fibroblasts adhesions to certain substrata can be explained by the 'focal adhesion' theory. On the other hand, epithelial cells adhere tn the substratum via hemidesmosomes. The typical integrin-mediated adhesions of cells to certain matrix are called 'cell-matrix adhsions'. The focal adhesion complex of fibroblasts, in relation to the cell-matrix adhsions, consists of the extracellular matrix(ECM) such as fibronectin, the transmembrane proteins such as integrins, the intracellular cytoplasmic proteins such as vinculin, talin, and more, and the cytoskeletal structures such as filamentous actin and microtubules. The mechanosensory function of integrins and focal adhesion complexes are considered to play a major role in the cells adhesion, migration, proliferation, differentiation, division, and even apoptosis. The '3-D matrix adhesions' defined by Cukierman et al. makes a promising future for the verification of the actual process of the cell-matrix adhesions in vivo and can be applied to the field of implant dentistry in relation to obtaining strong soft tissue attachment to the implant abutments.

• 한국건설순환자원학회논문집
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• 제5권2호
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• pp.177-184
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• 2017

최근 한국에서는 많은 지반 침하 사고가 발생하고 있는데, 이는 상하수의 누수 및 손상된 하수관에 기인한 것이다. 본 연구는 지반 침하에 대한 GPR 탐지 데이터의 실증적 자료를 구축하는 것을 목표로 한다. 이러한 목적으로 테스트 베드가 제작되었으며, 제작 변수는 주철관 및 EPS의 매입 깊이 및 수평 거리이다. 탐사결과, 1.5m의 깊이로 매립된 EPS는 검출하기 어려웠으며, 0.5m 거리 내에서 주철관에 밀접하게 매설 된 EPS는 매우 강한 주철관 신호로 탐지가 불가능했다. 또한 본 연구에서는 GPR 탐사 이미지 결과를 처리하기 위해 GPR 이미지 처리 프로그램 (GPRiPP)을 개발했다. 그 주요 기능은 위글파 신호를 증폭시키는 게인 기능이며, 기존 프로그램과 GPRiPP의 이미지 처리 기능은 매우 유사함을 확인하였다.

• 보건행정학회지
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• 제11권1호
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• pp.131-152
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• 2001

Public health system and public health practice have changed over the past decades as the result of social and epidemiologic changes. New public health concept emphasizes leadership, strategical thinking, systematic planning and effective performance to identify and solve complex health problem In Korea, the role of Health Center has been expanded rapidly. However there is strong suspicion that Health Center can achieve their mission. This paper aims at understanding what is the needed functions of Health Center and which of its aspects needs improvement. The main results of this study are summarizes as follows. District Health Law does not address the core functions of Health Center. The staffs of Health Center have difficulties in prioritizing their services. The recent attempt to restructure Health Center and change delivery pattern of public health services ended with only limited success. To effectively confront threats to the public's health, the three major function of Health Center must be ${\circled}1$ modifying individual behavior and lifestyle, ${\circled}2$ improving social and economic conditions, and ${\circled}3$ reforming health policies. Better results do not come from setting new functions only; they come from understanding and improving the processes that will then leads to better outcome. We recommend that policy-makers focus economic evaluation of public health programs, building and spreading of the scientific evidence of programs, linkage of public health research and public health program. The criteria of delegation of public health service to private sector is urgently needed. Making community health information data available on a routine basis to providers, managers and researchers of public health services helps promote the efficiency of the overall operation of public health system.

• 한국문헌정보학회지
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• 제17권
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• pp.229-259
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• 1989

The school library plays very important and central role for the fullfillment of educational objective in the process of implementing the school curriculum. And the media specialist known as teacher-librarian is. primarily responsible for the successful operation and effective management of the media center. It is true that effectiveness of the school library depends greatly on the cooperative coordination among teacher-librarian, teacher and principal in addition to the strong support and effective supervision of school district authority, specifically, supervisor of school library program. The successful program therefore is influenced by their perception of the teacher-librarian's role. The purpose of this study was to investigate the teacher-librarian's. educational role perceived by teacher-librarian, teacher, principal and school district supervisor. A standard task model describing both the management and educational functions and expectations of teacher-librarian was proposed after studying the relevant current standards of four countries. Serveral hypotheses were made regarding role perception and a survey instrument was designed based on this proposed task model and the results of the literature review to validate the hypotheses. The questionnaires were mailed out and the returned questionaires were analyzed by SPSS computer routine. The major findings are summarized as follows: 1) There was difference of the role perception among teacher-librarian, teacher, principal and district supervisor at the significance level of p<0.001 for both management and educational functions of teacher­librarian. The mean score of the teacher-librarian was highest among four groups and the score for the educational function tasks were lower than that of management function tasks. 2) The positive correlation exists at the significance level of p<0.001 between the role perception and the attitude toward changing social trends such as acceptance of new technology, need for better communication and information. 3) The positive correlation exists at the significance level of p<0.001 between the role perception and the view on the curriculum and teaching method.

• 대한지리학회지
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• 제29권3호
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• pp.360-368
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• 1994

地理學에서는 地域의 特性을 규명하고자 수많은 計量的 分析手法을 사용하여 왔다. 본 고에서는 일종의 判別分析技法으로 최근에 도입된 CHAID技法을 사용하여 都市와 都市 機能에 관한 통계처리를 시도하였다. 2종류의 자료를 가지고 두 차례 처리를 실시하였는데, 하나는 인구 25만명 이상의 도시 20개를 예측변수로 하고, 行政, 市場, 金融機能 그리고 生 産機能을 반응변수로 하여 도시의 기능을 분류해 내었다. 두번째 처리에서는 앞서 언급한 행정, 시장, 금융, 생산기능 이외에 交通, 敎育, 의료, 文化, 그리고 運送機能의 9가지를 예측 변수로 선정하고, 수도권, 부산권, 대구권, 광주권, 충청권의 5개 권역을 반응변수로 하여 각 권역에서 탁월한 기능을 판별, 분류해 내었다. 이상에서 CHAID기법은 큰 양의 범주형 자료 를 처리할 수 있고, 樹形圖로 결과를 산출하여 해석이 용이하므로 地域을 分類하거나 특성 을 判別하는데 유용한 또 하나외 새로운 분석틀로 여겨진다.