• Journal of Korean Biological Nursing Science
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• v.22 no.4
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• pp.279-287
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• 2020

Purpose: Some of the adolescent drinks more sugar-sweetened beverages. However, there is little evidence on the effect of eating behavior on emotional state and neurochemical changes under stress, especially on the levels of typical inhibitory neurotransmitters and gamma-aminobutyric acid. This article demonstrates that sucrose or saccharin drink reduces stress-related behavior responses and GABAergic deficits in adolescent rats. Methods: We randomly assigned 7-weeks-old Sprague-Dawley male rats to three groups: control group (Control), restraint stress only group (Stress), and restraint stress with unrestricted access to saccharin solution (Saccharin) and sucrose solution (Sucrose) as a positive control. We evaluated both anxious and depressive moods using an open field test and forced swim test, respectively. Using western blot analyses, the expression of a GABA-synthesizing enzyme, glutamate decarboxylase-67 (GAD67) and GABAergic markers, including calbindin and parvalbumin was assessed in the prefrontal cortex and the amygdala. Results: We found that both the drinks alleviated anxiety and depressive moods, induced significant attenuation in GAD67 level, and reduced calbindin level under stress in the prefrontal cortex and the amygdala. Conclusion: The results provide an understanding of the effect of sucrose or saccharin drink on stress-related responses. We propose the consumption of sweet drinks as a plausible strategy to alleviate stress-related alterations in adolescents.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.4
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• pp.44-54
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• 2020

Objectives : In the present study, we investigated whether or not an herb mixture including Lycii fructus(HML) has attenuation effects on light stress in rats. Methods : Light stress was induced by exposure to 300 lx of constant lifht for 24 h and 1mg/kg of caffeine was injected into the rat. Rats were orally treated with distilled water of HML for 21 days at 100mg/kg/d. The changes of mortality rate, clinical signs, body, blood chemistry, melatonin and IL-2 expression were analyzed after experiment. Results : Normal weight changes were observed in all treatment groups. In addition, no changes were observed in dead animals and general symptoms. At the time of autopsy, the appearance of all groups and gross examination of major organs were observed, and no gross findings were observed. Blood biochemical tests showed that total cholesterol and HDL cholesterol levels were statistically significantly decreased in the group treated with HML compared to the stress-induced group. Melatonin was measured in the blood, but there was no significant difference in the group treated with HML compared to the group with stress-induced group, but it tended to increase. IL-2 was measured in the blood, no significant change was observed in the group treated with HML compared to the stress-induced group. Conclusions : According to the above results, HML maybe help with hematological changes expressed by caffeine and light-induced stress.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2002.09a
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• pp.123-130
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• 2002

The ground-borne vibration from pile driving is causing many public discontents. However, because of the fact that the characteristics of wave propagation and attenuation are not well understood, systematic and effective vibration reduction measures can not be taken. This paper attempts to study the propagation of stress waves induced by the pile driving. To simulate the wave propagation in a semi-infinite domain, the so-called absorbing boundaries are incorporated in the finite element method and a series of numerical simulations is performed. Numerical results show that the surface displacement and velocity increase first and then decrease as the pile penetration depth becomes larges.

• Interaction and multiscale mechanics
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• v.6 no.1
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• pp.15-29
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• 2013

Phononic system composed of periodical elastic structures exhibit band gap phenomenon, and all elastic wave cannot propagate within the band gap. In this article, we consider one-dimensional binary materials which are periodically arranged as a 20-layered medium instead of infinite layered system for phononic system. The layered medium with finite dimension is subjected to a uniformly distributed sinusoidal loading at the upper surface, and the bottom surface is assumed to be traction free. The transient wave propagation in the 20-layered medium is analyzed by Laplace transform technique. The analytical solutions are presented in the transform domain and the numerical Laplace inversion (Durbin's formula) is performed to obtain the transient response in time domain. The numerical results show that when a sinusoidal loading with a specific frequency within band gap is applied, stress response will be significantly decayed if the receiver is away from the source. However, when a sinusoidal force with frequency is out of band gap, the attenuation of the stress response is not obvious as that in the band gap.

• Biomedical Science Letters
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• v.20 no.2
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• pp.56-61
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• 2014

This study attempted to confirm the antioxidative potential of luteolin against tert-butyl hydroperoxide (t-BHP) induced oxidative damage and to investigate its molecular mechanism related to glutathione (GSH)-dependent enzymes in HepG2 cells. Treatment with luteolin resulted in attenuation of t-BHP induced generation of reactive oxygen species (ROS) and oxidative stress-mediated cell death. In addition, accelerated expression of GSH-dependent antioxidative enzymes, glutathione peroxidase (GPx) and glutathione reductase (GR), and heme oxygenase (HO)-1, as well as strengthened GSH content was induced by treatment with luteolin, which was in accordance with increased nuclear translocation of nuclear factor-erythroid 2 p45-related factor 2 (Nrf2), a transcription factor for phase 2 enzymes, in a dose-dependent manner. These results suggest that the cytoprotective potential of luteolin against oxidative damage can be attributed to fortified GSH-mediated antioxidative pathway and HO-1 expression through regulation of Nrf2 in HepG2 cells.

• Journal of the Earthquake Engineering Society of Korea
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• v.10 no.1 s.47
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• pp.33-39
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• 2006

Parameters including the seismic sources and the elastic wave propagation characteristics were analysed using the observed ground motions from 3 Kyoungju region earthquakes. The Levenberg-Marquardt algorithm was applied to invert all the variables non-linearly and simultaneously with S wave energy In frequency domain. Average stress drop of 3 events and local attenuation parameter ${\kappa}$ were estimated to about 48-bar and 0.0312 respectively. Regional attenuation parameter, Qo and ${\eta}$, were also estimated to be about 417 and 0.83. ${\kappa}$ values are much higher than that of EUS, even though smaller than that of WUS. All these values resultant from this study show that there are differences in some parameters of other studios due to differences in the governing equation. of acceleration motions

• BMB Reports
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• v.42 no.2
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• pp.106-112
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• 2009

The bio-complex "reaction pattern in vertebrate cells"(RiV) is mainly represented by characteristic exosome-like particles - probably as reaction products of cells to specific stress. The transcription factor NF-kappaB plays a central role in inflammation. We tested the hypothesis that RiV particle preparations (RiV-PP) reduce cellular adhesion molecule (CAM) expression (ICAM-1, VCAM-1, E-selectin) by the attenuation of NF-kappaB translocation in human umbilical vein endothelial cells (HUVEC). After 4 hours, pre-incubation of HUVEC with RiV-PP before stimulation with TNF-alpha significantly reduced ICAM-1 (65.5${\pm}$10.3%) and VCAM-1 (71.1${\pm}$12.3%) mRNA expression compared to TNF-alpha-treated cells (100%, n=7). ICAM-1 surface expression was significantly albeit marginally reduced in RiV/TNF-alpha- treated cells (92.0${\pm}$5.6%, n=4). No significant effect was observed on VCAM-1 surface expression. In RiV/TNF-alpha-treated cells (n=4), NF-kappaB subunits p50 (85.7${\pm}$4.1%) and p65 (85.0${\pm}$1.8%) nuclear translocation was significantly reduced. RiV-PP may exert an anti-inflammatory effect in HUVEC by reducing CAM mRNA expression via attenuation of p50 and p65 translocation.

• Journal of the Earthquake Engineering Society of Korea
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• v.5 no.4
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• pp.17-26
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• 2001

In order to estimate peak ground motions and frequency characteristics of strong ground motions in southern korea, we employed the stochastic simulation method with the moment magnitude(M$_{w}$) and the hypocentral distance(R). We estimated same input parameters that account for specific properties of source and propagation processes, and applied them to the stochastic simulation method. The stress drop($\Delta$$\sigma$) of 100-bar was estimated considering results of research in ENA, China, and southern korea. The attenuation parameter x was calculated by analyzing 57 seismograms recorded from September 1996 to October 1997 and the estimation result of the attenuation parameter x is 0.00112+0.000224 R where R is hypocenter distance. We estimated strong ground motion relations using the stochastic simulation method with suitable input parameters(e.g. $\Delta$$\sigma$, x, and so on). At last, we derived relations between hypocentral distances and ground motions(seismic attenuation equation) using results of the stochastic prediction.esults of the stochastic prediction.n.

• Journal of Power System Engineering
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• v.20 no.6
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• pp.58-63
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• 2016

A stainless steel has high corrosion resistance because of nickel in material, so it is used as materials for transportation and storage of hydrogen. In this study, TIG(tungsten ingot gas) welding was carried out on the stainless steel using the storage vessel of hydrogen. The microscopic structures at each region of TIG welded material such as HAZ, weld and base metals using optical microscope were observed. And the damage behavior of stainless steel that underwent the hydrogen charging using nondestructive evaluation was also studied. Ultrasonic test, which is the most generalized nondestructive technique, was applied to evaluate the relationship between the ultrasonic wave and mechanical properties at each zone of TIG welded stainless steel. The velocity and attenuation coefficients of ultrasonic wave didn't show a remarkable difference at each region of welded stainless steel. However, the attenuation coefficient was the highest at the weld zone when hydrogen charged stainless steel. In addition, acoustic emission test was also used to study the dynamic behavior of stainless steel experienced both hydrogen charging and weld. Lots of AE event at elastic region of stress-strain curve were occurred both the hydrogen charged specimen and the free specimen.

• Journal of the Korean Society for Nondestructive Testing
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• v.20 no.5
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• pp.402-411
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• 2000

This study investigates the method to measure the viscoelastic properties of asphalt cement, one of the viscoelastic materials, using the ultrasound. The wave speed and attenuation were measured from $-20^{\circ}C$ to $60^{\circ}C$ at the frequency of 2.25MHz. Then, the storage and loss longitudinal moduli, loss tangent storage and loss longitudinal compliances were found depending on the temperatures based on the linear viscoelastic theory. Stress relaxation, creep, and viscosity were predicted using Maxwell and Voigt-Kelvin viscoelastic models. The validity of superposition principle and shift factor were verified by comparing the present results to the data reported in the literatures.