• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7859-7863
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• 2015

Purpose: To compare the efficacy and toxicity of gemcitabine versus docetaxel in a second-line setting of nonsmall cell lung cancer (NSCLC) patients previously treated with platin-based combination chemotherapy. Materials and Methods: We retrospectively evaluated the medical records of 57 patients treated with single agent gemcitabine or docetaxel in second-line setting of advanced NSCLC who received one prior platinum-based therapy. Results: The mean age was $56.7{\pm}8.39$ years with 55 (96.5%) males and two (3.5%) females. Forty of them received docetaxel and 17 gemcitabine. The mean number of chemotherapy cycles was $6.8{\pm}4.0$ in the gemcitabine group, while it was $4.6{\pm}3.0$ in the docetaxel group. Overall response rates were 8% and 12% (P=0.02) for gemcitabine and docetaxel, respectively. The median survival time was 22 versus 21 months for gemcitabine and docetaxel, respectively. The median times to progression were 8 and 5 months. There was no difference between the two groups in terms of incidence of adverse affects (40% vs 47.1%). All of the hematological side effects were grade 1/2. No major toxicity was encountered necessitating stopping the drug for either group. Conclusions: Treatment with gemcitabine demonstrated clinically equivalent efficacy with a significantly improved safety profile compared with those receiving docetaxel in the second-line setting for advanced NSCLC in this study. Based on these results, treatment with gemcitabine should be considered a standard treatment option for second-line NSCLC.

• 정보처리학회논문지C
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• 제11C권3호
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• pp.353-360
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• 2004

본 논문에서는 반복복호부호의 복호과정시 CRC(Cyclic Redundancy Check)검사를 이용하여 반복복호수가 가변하는 효율적인 제어기법을 제안한다. 반복복호 부호는 반복구조를 가지며 그 특성상 반복복호수가 증가할수록 BER/FER성능이 우수하게 향상된다. 그러나 반복복호수가 증가할수록 복호과정시 적용된 알고리즘의 복잡도에 따라 다소 차이는 있지만 공통적으로 계산량의 증가를 가지게 되며 이는 복호지연시간 증가로 나타난다. 또한 일정 반복복호수 이상에 도달하게 되면 그 성능 변화가 거의 없는 오류마루(error floor)현상이 나타난다. 즉 성능변화가 없는 적절한 반복복호수 종료점을 찾아야 한다. 따라서 본 논문에서는 프래임 주기로 수신된 정보를 프래임 오류검사 지시자(FCS : Frame Check Sequence Indicator)를 이용하여 채널의 변화를 감시하며 반복복호 부호의 반복복호 횟수를 채널 적응적으로 증가, 감소할 수 있도록 제어하는 기법을 제안하여 결과적으로 반복구조를 가지는 부호의 방대한 계산량 감소와 이로 인한 복호지연 시간을 성능저하 없이 효율적으로 단축시킬 수 있음을 확인하였다.

• 한국통신학회논문지
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• 제33권11B호
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• pp.1030-1037
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• 2008

본 논문에서는 다중 로봇 (multi-robot)을 활용한 응용분야 중, 미지의 영역에 대한 탐색 (exploration) 능력을 향상시켜서, 주어진 미로 (maze)에서 다중 로봇이 통신을 통해서 협력적으로 출구를 찾아가는 효율적인 방안을 제안하였다. 즉, 미로 형태의 임의의 환경을 생성한 후, 로봇을 무작위로 배치시켜 상호간에 통신을 통하여 출구로 신속히 모두 빠져나오는 문제를 다루고 있다. 미로탐색을 위해 다중 로봇의 지역 탐색에서 사용되었던, 프론티어 셀, 셀 유틸리티등 기존 연구를 활용하였다. 또한 로봇간의 다중홉 무선 통신 (multihop wireless communications)을 위해서 이동성 (mobility)에 강한 일종의 홉기반 (hop-by-hop) 라우팅인, 랜덤 베스킷 볼 라우팅을 채용하였다. 또한, 출구를 찾은 로봇이 일정한 확률에 의거하여 출구 앞에서 정지하거나 혹은, 빠져나가는 의사 결정을 하여, 이 확률적인 결정이 다른 로봇의 행동에 어떻게 영향을 주는지를 실험적으로 조사하였다. 즉, 출구를 찾은 로봇이 현재 위치에서 멈추어서, 통신 중계 지점 (relay)으로 어떻게 활동되어야 최적인지에 대한 문제를 모의 실험을 통해 파악해보았다.

• 음성과학
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• 제11권2호
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• pp.71-87
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• 2004

Korean has a pair of voiceless fricatives, whose laryngeal manifestation comes in parallel to stops and affricates with a three-way lexical contrast. Prior phonetic studies by Kagaya (1974), Iverson (1983), and Kang (1999, 2000) point out /s/ is associated with multiple characteristics of the larynx shared with not only the lax but also the aspirated series, whereas /s' / carries a laryngeal distinction typical of the tense consonants. The complex dual nature of /s/ is again supported by a psycholinguistic study by Kang (2004), as /s/ was found to interact with /$c^h$/ (17% of the time) as well as /c/ (57%) in speech errors. In addition, a recent work by Cho and Lee (2003) notes an interesting chain shift case in the acquisition of the fricatives. Although they observed a significant phonological pattern between child English and Korean, Cho and Lee's description of acquiring fricatives is far from being precise from the perspective of phonetics. From a longitudinal study of recorded tapes by two children at 1;7-3;8 and 1;7-2;1 respectively, I found that /s' / was usually substituted into tense noncontinuants in young children's early production as predicted, whereas /s/ having both lax and aspirated-like glottal properties revealed a complicated pattern of substitutions into lax, tense, and aspirated noncontinuants with a varying degree of preference relative to the subjects. The current acquisition study supports the previous claims concerning fricatives in other languages, showing that their acquisition comes after stops. Besides, it also notes that Korean fricatives are subject to a series of phonological processes called stopping, affricating, tensifying and palatalizing during the transitional period of phonological development by young children. Moreover, between the two voiceless types, /s/ was acquired earlier than /s'/ as the unmarked segment.

• 동의생리병리학회지
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• 제24권4호
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• pp.533-542
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• 2010

Skin aging is a natural phenomenon. There are internal and external factors of skin aging. The internal factor of skin aging is from the wearing down of the body over time. The external factors are more noticeable from habits such as smoking, excessive alcohol, malnutrition, and extended exposure to UV rays. Completely stopping skin from aging is impossible but one can slow down and treat external signs of skin aging. In western medicine, the following methods are used to reduce the appearance of skin aging: applying lotions and creams containing ingredients such as fruit acid, antioxidants, plant exracts, depigmentation, moisturizer, retinoids, and sun block; botulinum toxin injections; chemical peels, laser and other painful methods remove the top layer of skin to promote new skin growth; fillers are injected to increase soft tissue growth; surgery. In oriental medicine, the following methods are used: acupuncture into facial muscles which stimulates acupuncture point; applying topical treatments and cosmetics containing herbs are effective of preventing skin aging and wrinkles. Above all thing, medicine that helps maintain essence and blood in the skin can be fundamental.

• 한국방재학회 논문집
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• 제8권3호
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• pp.37-42
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• 2008

본 연구는 지하철에서 화재발생시 최적의 제연모드 예측을 목적으로 수치해석을 수행하였다. 현재 국내 지하철 화재발생시 제연모드는 승강장 내 화재구역 배기, 비화재구역 급기 또는 정지로 설정 되어있다. 수치해석 조건은 2가지 국내 비상시 제연모드 및 발화 4분(승강장 피난허용시간, NFPA 130) 이전까지 승강장에서 배기를 하며, 발화 4분이 후 터널 배기로 전환되는 스위치모드의 3가지 경우에 대하여 비교 분석하였다. 승객 호흡높이(1.7 m)를 기준으로 열, 일산화탄소 및 가시거리를 비교하였다. 수치해석 결과 급기팬 작동은 연기를 교란시키고 확산시킬 수 있으며, 또한 승강장 및 터널 제연모드로 작동할 경우 승강장의 제연모드로만 작동한 경우에 비하여 연기 배출에 효과적임을 확인할 수 있었다.

• 대한한방부인과학회지
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• 제19권1호
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• pp.251-260
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• 2006

Purpose : To assess the duration of the therapeutic effect and recurrence symptoms after stopping Herb Medication therapy for climacteric womens. Methods : 28 climacteric womens received only Daejo-hwan(DJH): 2pills(4g) a time, three times a day for a total 8 weeks as maintenance therapy and were followed up for 3 months. Grading of climacteric symptoms were measured by Kupperman's index(K.I.), Greene scale(G.S.) and MRS. Results : The results were as follows. 1. After DJH-treatment, the climacteric symptoms were improved and each mean score of K.I., G.S., and MRS reduced significantly. 2. At 3 months after the end of treatment(EOT), each mean score of K.1., G.S., and MRS reduced significantly as compared with Baseline, and increased significantly as compared with EOT. 3. At 3 months after EOT, each climacteric symptoms kept up the favorable turn and the mean score of MRS reduced significantly as compared with Baseline, but made no significant difference as compared with EOT. Conclusion : In this study, we can consider the DJH-treatment therapeutic effect was kept up for 3 months after EOT and recurrence symptoms did not appeared after EOT to climacteric womens.

• 항공우주정책ㆍ법학회지
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• 제16권
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• pp.160-196
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• 2002

In this thesis. I have first introduced and studied Chubb & Son. Inc. v. Asiana Airlines. 214 F.3d 301 (2nd Cir. 2000). which held that at the time that the dispute in this case arose. there was no treaty relationship between the United States and South Korea under the Original Warsaw convention. the Hague Protocol. or a treaty consisting of those provisions of the Original Convention that were not amended by the Protocol. And I have analyzed U.S. government s position that was expressed in Brief for the United States as Amicus Curiae on petition for a writ certiorari to the 2nd Circuit on Chubb & Son case and 2nd Circuit s Fujitsu Limited v. Federal Express Corporation. 247 F.3d 423 (2001) which was held in a related question afterwards but was somewhat inconsistent with Chubb & Son s holding. Furthermore. I also examined U.S. government s measures which have been considered and taken to cope with consequences of Chubb & Son case's ruling. Lastly. I have examined several effects which Chubb & Son s ruling would give our nation s airlines and suggested our government's countermeasures.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1998년도 하계학술대회 논문집 C
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• pp.1166-1169
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• 1998

The Load characteristic of electric railway requires the power demand of the high capacity which amplitude is spacial-temporally fluctuated due to frequent starting and stopping with large tractive force. The conventional electric railway mainly consists of the resistance controlled and the thyristor controlled locomotives, are compensated for their bad characteristics of the power factor$(70\sim80%)$ with installation of another capacitor improving power factor at the substation. Since 1994, VVVF train car with good characteristics of power factor(100%) have been introduced and operated in Kwa-Chon Line. From the present technical tendency, it is judged that introduction of the locomotive with various controlled methods is necessary. The protective equipments installed at the substation are complicated and various aspects to detect faults and reduce their extension, so the universal countermeasures are required. Specially in the case of the fault occurrence it is difficult to calculate the fault location because of the change in the contactline constant according to modifying the characteristics of the contactline (the dualized catenary wire and extension, etc), so much time is required for the detection of fault location. In BT-fed method distance-relays and fault-locators are not installed, we have so many difficulties in the quick accident recovery.

• 지역사회간호학회지
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• 제12권3호
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• pp.716-731
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• 2001

The purpose of this study was to test the effect of a self-efficacy promotion smoking cessation program for middle school students. This program was redesigned on the basis of Shin Sung Rye( 1997)' s Self-Efficacy Promoting Program for this study. The design of this paper was quasi-experimental. equivalent control group pre-post test. time series design. The subjects of this study were 53 smoker adolescents in D Middle School in the city of Busan. The results were summarized as follows: 1) The Hypothesis 1 was accepted: The self efficacy of the experimental group was higher than that of the control group after 1 week (expected efficacy t=2.20, p<.05. expected outcomes t=-2.58. p<.05) 4 weeks after education (expected efficacy t=- .19. p<.001, expected outcomes t=-2.586. p<.05). 2) The Hypothesis 2 was accepted: The amount of smoking of the experimental group was reduced more than that of the control group after 1 week (t=2.05, p<.05) and after 4 weeks (t=2.03. p<.05). 3) The Hypothesis 3 was accepted: The positive urine cotinine of the experimental group was less than that of the control group after 1 week after education($x^2$=8.57. p<.01) after 4 weeks ($x^2$=22.49. p<.001). In conclusion. a self-efficacy promotion smoking cessation program for middle school students was an effective smoking cessation program and then it will be valuable for stopping the smoking among the adolescents.