• Title/Summary/Keyword: stimulus intensity

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Surface Mapping of Masseter for Botulinum Toxin Injection (교근에서 보툴리눔 독소 주사점의 표지화)

  • Kim, Jun Hyung;Lee, Min Jae;Kim, Hyun Ji;Son, Dae Gu;Han, Ki Hwan;Lee, So Young;Lim, Jung Guen;Choi, In Jang
    • Archives of Plastic Surgery
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    • v.32 no.3
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    • pp.311-313
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    • 2005
  • Generally, many Asian women tend to dislike the square jaw, as they believe it makes the face look wider, giving a stubborn and strong impression. Contouring of the mandible is therefore a relatively common aesthetic procedure among Asians. These days, the use of botulinum toxin for contouring of the lower face offer simple alternative to surgery. Motor point, which is the site over a muscle where its contraction may be elicited by a minimal intensity short duration electrical stimulus, is the optimal injection point of botulinum toxin. Study was undertaken to identify the location of motor point of the masseter muscle and the skin surface landmark. First, the thickest point of the masseter muscle was inspected through palpation and inspection by 3 different individual plastic surgeons and then compound muscle action potentials(CMAPs) of masseter muscle in 15 health volunteers were recorded using EMG. For the localization of the measured points, line between lateral canthus to the mandibular angle was used. Location of motor points were mapped to skin surface from lateral canthus in a percentage of the distance along the landmark line and in distance in millimeters. The clinical injection point was located at 71.69 percentile and 7.3 mm of the landmark line. The motor point test was located at 72.54 percentile and 7.1 mm of the landmark line. The depth of motor point was 16mm. There was no statistically significant difference between the clinical injection point and the motor point. We conclude that surface mapping of motor point of the masseter muscle would increase accessibility and accuracy in botulinum toxin injection for contouring of the lower face.

Generation of Reactive Oxygen Species in Porcine Parthenogenetic Embryos

  • Hwang, In-Sun;Park, Choon-Keun;Yang, Boo-Keun;Cheong, Hee-Tae
    • Reproductive and Developmental Biology
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    • v.35 no.2
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    • pp.191-195
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    • 2011
  • The present study was conducted to examine the reactive oxygen species (ROS) generation levels in porcine parthenogenetic embryos. Porcine in vitro matured oocytes were activated by the combination of electric stimulus and 6-DMAP before in vitro culture. Porcine oocytes and parthenogenetic embryos were stained in 10 ${\mu}M$ dichlorohydrofluorescein diacetate (DCF) or 10 ${\mu}M$ hydroxyphenyl fluorescein (HPF) dye each for 30 min at $39^{\circ}C$. The fluorescent emissions from the samples were recoded as JPEG file and the intensity of fluorescence in oocytes and embryos were analyzed. $H_2O_2$ and $^{\cdot}OH$ radical levels of porcine oocytes were reduced immediately after electric stimulation. However, $H_2O_2$ and $^{\cdot}OH$ radical levels of parthenogenetic embryos were increased with time elapsed after electric stimulation from 0 h to 3 h and after DMAP culture. During in vitro culture, $H_2O_2$ and $^{\cdot}OH$ radical levels were gradually increased from the one-cell stage to the two- and four-cell stages. The result of the present study suggests that the ROS was not increased by electric pulse in porcine embryos. Rather than it seems to be associated with the stage of development and the culture condition.

Analysis of Lung Function Influences by Stimulating Ear Reflex Point Using Voice Analysis (음성 분석을 통한 폐 이혈점 자극이 폐 기능에 미치는 영향 분석)

  • Kim, Bong-Hyun;Cho, Dong-Uk
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37 no.6C
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    • pp.520-526
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    • 2012
  • Mostly lung diseases by smoking and air pollution is increasing social interest one of 6 kinds of modern diseases which is difficult functional recovery of damaged lung as dangerous diseases of life extension. Therefore, to reduce suffering from respiratory diseases is usually non-smoking, to do strengthen behavior of lung function. In this paper, we would like to propose method to do investigation by voice analysis technology to apply when lung associated ear acupuncture point stimulus to help strengthen actually lung function. From this, we would like to consider the voice change of before/after in smoking to analyze the impact on the human body to the lungs. Based on this experiment, we would like to investigate numerically quantity data actual improved lung function to analyze of voice character difference of before/after in lung associated ear acupuncture point stimulating.

Assessment of Pulsed Magnetic Field Stimulus by Using Finger Photoplethysmogram and Pressure Pulse Waveform

  • Lee, Jin-Yong;Go, In-Suk;Choi, Jae-Won;Jang, Tae-Sun;Shin, Sang-Hoon;Lee, Hyun-Sook;Hwang, Do-Guwn;Kim, Sun-Wook
    • Journal of Magnetics
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    • v.15 no.4
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    • pp.209-212
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    • 2010
  • Photoplethysmogram (PPG) and pressure pulse waveform (PPW) were compared and evaluated for the efficacy of stimulating knuckles by using the pulsed magnetic field. Both signals were observed simultaneously while the knuckles were exposed for 10 min to the pulsed magnetic field, with maximum field intensity of 0.8 T and transition time of 0.126 msec. After 5 min stimulation of the knuckles, the results showed that the aging indexes calculated from the second derivative of the PPG were increased from -1.913 to 0.072, and that of the PPW from -0.063 to 0.387. However, for the relatively long-term stimulation for 10 min, we found that the values of both the aging indexes of the second derivatives and augmentation index of the PPW returned to the starting level. The changes observed in characteristic factors such as the aging indexes of the second derivatives and augmentation index of the PPW indicate the potential of pulsed magnetic field stimulation as a therapeutic method for the treatment of patients with peripheral vascular disease.

Effect of Electrical Stimulation of Peripheral Nerve on Pain Reaction (말초신경자극이 동통반응에 미치는 영향)

  • Paik, Kwang-Se;Chung, Jin-Mo;Nam, Taick-Sang;Kang, Doo-Hee
    • The Korean Journal of Physiology
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    • v.15 no.2
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    • pp.73-81
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    • 1981
  • Experiments were conducted in ischemic decerebrate cats to study the effects of electroacupuncture and electrical stimulation of peripheral nerve on pain reaction. Flexion reflex was used as an index of pain. The reflex was elicited by stimulating the sural nerve(20 V, 0.5 msec duration) and recorded as a compound action potential from the nerve innervated to the semitendinosus muscle. Electroacupuncture was performed, using a 23-gauge hyperdermic needle, on the tsusanli point in the lateral upper tibia of the ipsilateral hindlimb. The common peroneal nerve was selected as a peripheral nerve which may be associated with electroacupuncture action, as it runs through the tissue portion under the tsusanli point. Both for electroacupuncture and the stimulation of common peroneal nerve a stimulus of 20 V-intensity, 2 msec-duration and 2 Hz-frequency was applied for 60 min. The results are summerized as follows: 1) The electroacupuncture markedly depressed the flexion reflex; this effect was eliminated by systemic application of naloxone $(0.02{\sim}0.12\;mg/kg)$, a specific narcotic antagonist. 2) Similarly, the electrical stimulation of the common peroneal nerve significantly depressed the flexion reflex, the effect being reversed by naloxone. 3) When most of the afferent nerves excluding sural nerve in the ipsilateral hindlimb were cut, the effect of electroacupuncture on the flexion reflex was not observed. Whereas direct stimulation of the common peroneal nerve at the proximal end from the cut resulted in a significant reduction of the flexion reflex, again the effect was reversible by naloxone application. 4) Transection of the spinal cord at the thoracic 12 did not eliminate the effect of peripheral nerve stimulation on the flexion reflex and its reversal by naloxone, although the effect was significantly less than that in the animal with spinal cord intact. These results suggest that: 1) the analgesic effect of an electroacupuncture is directly mediated by the nervous system and involves morphine-like substances in CNS, 2) the site of analgesic action of electroacupuncture resides mainly in the brainstem and in part in the spinal cord.

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Triggered Electrooculography for Identification of Oculomotor and Abducens Nerves during Skull Base Surgery

  • Jeong, Ha-Neul;Ahn, Sang-Il;Na, Minkyun;Yoo, Jihwan;Kim, Woohyun;Jung, In-Ho;Kang, Soobin;Kim, Seung Min;Shin, Ha Young;Chang, Jong Hee;Kim, Eui Hyun
    • Journal of Korean Neurosurgical Society
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    • v.64 no.2
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    • pp.282-288
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    • 2021
  • Objective : Electrooculography (EOG) records eyeball movements as changes in the potential difference between the negatively charged retina and the positively charged cornea. We aimed to investigate whether reliable EOG waveforms can be evoked by electrical stimulation of the oculomotor and abducens nerves during skull base surgery. Methods : We retrospectively reviewed the records of 18 patients who had undergone a skull base tumor surgery using EOG (11 craniotomies and seven endonasal endoscopic surgeries). Stimulation was performed at 5 Hz with a stimulus duration of 200 μs and an intensity of 0.1-5 mA using a concentric bipolar probe. Recording electrodes were placed on the upper (active) and lower (reference) eyelids, and on the outer corners of both eyes; the active electrode was placed on the contralateral side. Results : Reproducibly triggered EOG waveforms were observed in all cases. Electrical stimulation of cranial nerves (CNs) III and VI elicited positive waveforms and negative waveforms, respectively, in the horizontal recording. The median latencies were 3.1 and 0.5 ms for craniotomies and endonasal endoscopic surgeries, respectively (p=0.007). Additionally, the median amplitudes were 33.7 and 46.4 μV for craniotomies and endonasal endoscopic surgeries, respectively (p=0.40). Conclusion : This study showed reliably triggered EOG waveforms with stimulation of CNs III and VI during skull base surgery. The latency was different according to the point of stimulation and thus predictable. As EOG is noninvasive and relatively easy to perform, it can be used to identify the ocular motor nerves during surgeries as an alternative of electromyography.

Neuro-controller for Broadcast Lighting LED to Express xy Chromaticity Coordinates (xy 색도좌표 표현을 위한 방송 조명용 LED 신경망 제어기)

  • Park, Sung-Chan;Park, Jin-Hyun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.24 no.6
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    • pp.706-713
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    • 2020
  • To control the LED lighting for broadcasting, LED current control using tri-stimulus values is used for RGB LEDs. For the convenience of control, this control is approximated as a linear function or used as an appropriate value through trial and error. Also, it is not suitable for broadcast lighting because it does not use a diffuser plate applied for mixing sufficient light and color required for actual it. In this study, a neural network with excellent nonlinear function approximation is used as a control method for LED panels for broadcast lighting. We intend to implement an LED panels controller suitable for the desired chromaticity coordinates and dimming values of intensity. As a result of the performance evaluation, the errors of the xy chromaticity coordinates are mostly ±0.02 and the acceptable range of ANSI C78.377A was satisfied. The average errors of the xy chromaticity coordinate are xerror=0.0044 and yerror=0.0030, respectively, and we confirmed the superiority and stable performance of the proposed algorithm.

Technical Considerations of Effective Direct Cortical and Subcortical Stimulation (효과적인 대뇌 직접피질자극 검사 및 피질하자극 검사의 술기에 관한 기술적 고찰)

  • Lim, Sung Hyuk;Jang, Min Hwan
    • Korean Journal of Clinical Laboratory Science
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    • v.54 no.2
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    • pp.157-162
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    • 2022
  • The purpose of the direct cortical and subcortical stimulation technique is to prevent false positives caused by transcranial electrical motor evoked potentials (TceMEP) in surgery on patients with brain tumors that have occurred around the motor cortex and to preserve the correct mapping of motor areas during surgery and the corticospinal tract. In addition, it reduces the trial and error that occurs during the intraoperative neurophysiological monitoring (INM) process and minimizes the test time, so that accurate information is communicated to the surgeon with quick feedback on the test results. The most important factors of this technique are, first, examination at a stimulus threshold of a certain intensity, and second, maintaining anesthesia depth at an appropriate level to prevent false positives from occurring during surgery. The third is the installation of a multi-level channel recording electrode on the opposite side of the area of operation to measure the TceMEP waveform and the response to direct cortical and subcortical stimulation in as many muscles as possible. If these conditions are maintained, it is possible to predict causes that may occur in other factors, not false positives, from the INM test.

Relationship between the Level of Depression and Facial EMG Responses Induced by Humor among Children (유머에 의해 유발된 아동의 안면근육반응과 우울 수준과의 관계)

  • Jang, Eun-Hye;Lee, Ju-Ok;Sohn, Sun-Ju;Lee, Young-Chang;Sohn, Jin-Hun
    • Science of Emotion and Sensibility
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    • v.13 no.1
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    • pp.33-40
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    • 2010
  • The study is to examine relationship between the level of depression and facial EMG responses during the humor condition. Forty-three children(age range 22-49 years) participated in the study. The Korean Personality Inventory for Children(KPI-C) was used to measure the level of depression in children. While children were presented to audio-visual film clip inducing humor, facial EMG were measured on their faces(bilateral corrugators and orbicularis). A baseline state was measured during 60 seconds before the presentation of the stimulus, i.e., emotional state lasting 120 seconds. Participants were asked to report the intensity of their experienced emotion. The results of emotion assessment showed 95.3% appropriateness and 3.81 intensity on the 5 points Likert scale). Facial EMG showed a significant increase while participants experiencing humor compared to baseline state. Additionally, the result showed a negative correlation between right corrugator responses and the level of depression. The study findings showed the more children experienced depression, the less facial EMG activity they had while experiencing humor.

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Role of the Vestibular and Medullary Reticular Neuclei for the Motor Evoked Potentials in Rats (흰쥐의 운동유발전위에 대한 전정신경핵과 연수망상핵의 역할)

  • Lee, Moon-Young;Lee, Sung-Ho;Kim, Jae-Hyo;Park, Byung-Rim;Kim, Min-Sun
    • The Korean Journal of Physiology and Pharmacology
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    • v.1 no.6
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    • pp.603-611
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    • 1997
  • The motor evoked potentials (MEPs) have been advocated as a method of monitoring the integrity of spinal efferent pathways in various injury models of the central nervous system. However, there were many disputes about origin sites of MEPs generated by transcranial electrical stimulation. The purpose of present study was to investigate the effect of major extrapyramidal motor nuclei such as lateral vestibular nucleus (VN) and medullary reticular nucleus (mRTN) on any components of the MEPs in adult Sprague-Dalwey rats. MEPs were evoked by electrical stimulation of the right sensorimotor cortex through a stainless steel screw with 0.5mm in diameter, and recorded epidurally at T9 - T10 spinal cord levels by using a pair of teflon-coated stainless steel wire electrodes with 1mm exposed tip. In order to inject lidocaine and make a lesion, insulated long dental needle with noninsulated tips were placed stareotoxically in VN and mRTN. Lidocaine of $2{\sim}3\;{\mu}l$ was injected into either VN or mRTN. The normal MEPs were composed of typical four reproducible waves; P1, P2, P3, P4. The first wave (P1) was shown at a mean latency of 1.2 ms, corresponding to a conduction velocity of 67.5 m/sec. The latencies of MEPs were shortened and the amplitudes were increased as stimulus intensity was increased. The amplitudes of P1 and P2 were more decreased among 4 waves of MEPs after lidocaine microinjection into mRTN. Especially, the amplitude of P1 was decreased by 50% after lidocaine microinjection into bilateral mRTN. On the other hand, lidocaine microinjection into VN reduced the amplitudes of P3 and P4 than other MEP waves. However, the latencies of MEPs were not changed by lidocaine microinjection into either VN or mRTN. These results suggest that the vestibular and reticular nuclei contribute to partially different role in generation of MEPs elicited by transcranial electrical stimulation.

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