• The Journal of Korean Academic Society of Nursing Education
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• v.22 no.4
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• pp.504-513
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• 2016

Purpose: The purpose of this study was to identify the mediating effect of self-efficacy in the relationship between emotional intelligence and clinical performance in nursing students. Methods: Data were collected through structured questionnaires between March 1 and March 25, 2016. Study participants were 223 fourth year nursing students in B and K metropolitan city. Data were analyzed using t-test, ANOVA, Scheffe' test, Pearson's correlation coefficients, and hierarchical multiple regression with SPSS WIN v 18.0. Results: The mean scores of emotional intelligence was $3.85{\pm}0.43$, self-efficacy was $3.25{\pm}0.40$, and clinical performance was $3.63{\pm}0.51$. There were significant positive correlations between emotional intelligence, self-efficacy and clinical performance. There were partial mediating effect of self-efficacy in the relationship between emotional intelligence and clinical performance. Conclusion: In order to enhance nursing students' clinical performance, strategies for intervention development such as stimulating emotional intelligence and motivation by self-efficacy are necessary.

• Journal of Physiology & Pathology in Korean Medicine
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• v.30 no.5
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• pp.314-319
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• 2016

Mucus in the respiratory system is a factor to cause not only respiratory diseases but also chronic diseases. In this regard, this study is to investigate whether Benincasa hispida extracts (BHE) would stimulate secreting mucus in trachea and tracheobronchial lumen of rats. As a result, effect of stimulating the mucus secretion into trachea and trachebronchial lumen of rats is significantly increased in accordance with the administration concentration of Benincasa hispida seed extracts (BHSE). The secretion amounts of phenol red (PR) and sodium fluoreseceine (NaFI) are significantly increased by 25% and 34%, respectively, when 70% EtOH extracts of Benincasae pericarpium (BPE) are administrated to rats at the concentration of 200 mg/kg. In addition, the secretion amounts of PR and NaFI are significantly increased when BuOH fraction and water fraction are intraperitoneally administrated to rats at the concentration of 200 mg/kg. It seems the result implies the physiologically active substance that stimulates the secretion of mucus is contained in Benincasa hispida. Thus, Benincasa hispida is considered to be effective for Korean medicine treatment as a medicinal plant having effect of antitussive and apophlegmatic, and it also can be useful in developing functional food and beverage.

• Korean Journal of Pharmacognosy
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• v.46 no.4
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• pp.315-320
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• 2015

This study was carried out to investigate the effect of ethanolic extract Salicornia herbacea (SHEE) on melanogenesis and mechanism. The SHEE on ${\alpha}$-melanocyte stimulating hormone (${\alpha}$-MSH) induces melanogenesis in B16F10 melanoma cells. The effect of SHEE remarkably decreased protein expression of tyrosinase and tyrosinase relate protein (TRP)-2 increased extracellular signal related kinase (ERK) on ${\alpha}$-MSH 100 nM induced melanogenesis on B16F10 melanoma cells at dose-dependent manner. It has been reported that the activation of ERK reduce melanin synthesis by down-regulating micro-phthalmia-associated transcription fator (MITF). These results sugggest that possibility of extracted korean medicinal herbs as a functional ingredient for whitening cosmetic formula.

• Journal of Ginseng Research
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• v.10 no.2
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• pp.123-132
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• 1986

The pepsinogen secretion was stimulated by the cholecystokinin, caerulein, isoproterenol, and carbachol, respectively. But it was increased slightly and returned to control level by the combiantions of total saponin with each above the agents. Even though the atropine had the inhibition effect, the pepsinogen secretion was recovered to normal level from depressed condition by the combination of the atropine with total saponin. Propranolol showed the same pattern as atropine, too. On the other hand, the pepsinogen secretion was stimulated by the DBcAMP alone, but decreased to control level by the combination with the total saponin. In the case of DBcGMP, the pepsinogen secretion was decreased by itself, but stimulated the above control level by the combination with total saponin. Histamine alone had little effect on the pepsinogen secretion, but when combinated with total saponin, the pepsinogen secretion was increased. Serotonin alone and with total saponin, had no effect respectively, From the above results, the total saponin may have the normalization action stimulating or decreasing the pepsinogen secretion to the control level.

• Archives of Pharmacal Research
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• v.28 no.5
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• pp.566-572
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• 2005

The aim of this study was to determine if the isoflavones from Sophorae fructus (SISO) have potential clinical benefit in hormone replacement therapy (HRT) for the treat ment of menopausal signs, such as the levels of total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL) and follicle stimulating hormone (FSH). An additional aim was to present the potential antioxidant effect of SISO in a microglial cell line. For the animal model, the ovaries were removed from adult rats and the indicators of menopause were measured at the pre- and post-administration time points. Although no statistically significant correlation was found, SISO tended to decrease the TC level (p=0.15) and the FSH level (p=0.36), but to increase the HDL level (p=0.303).SISO (< 5${\mu}g$/mL) also exerted antioxidant activity on BV-2 microglial cells by inhibiting lipopolysaccharide-induced nitric oxide. This cytoprotective effect was confirmed by trypan blue staining, which was used to test for cellular damage from H$_2O_2$. In conclusion, this study highlights the anti-menopausal and antioxidant effect of SISO in an ovariectomized rat model, as well as in microglial cells, and provides new clinical targets for the screening of phytoestrogens as potential candidates for HRT in menopausal women.

• Journal of Veterinary Clinics
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• v.20 no.1
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• pp.49-51
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• 2003

This study was performed to evaluate the effect of acupuncture on gastric motility in dogs with radiography and ultrasonography. All experimental dogs were fed with the soup with barium (3% W/V), and thereafter gastric emptying time(GET) was measured with radiography and ultrasonography with Bolondi's method. The acupoints were CV-12, PC-6, ST-36 and BL-21 in this experiment. On these acupoints, electroacupunctral stimulation(15 MHz, continous wave) was applied for 20 minutes. The results were as follows: In the control group, normal GET was 70-85 minutes with ultrasonography, and 110-130 minutes with radiography. In acupuncture stimulation groups, there was no effect of gastric motility in CV-12, PC-6, and 57-36, whereas there was significant stimulating effect of gastric movement in BL-21 with ultrasonography (P < 0.05) and radiography (P < 0.01). Above these results, it is concluded that acupunctural stimulation of BL-21 was more effective in gastric motility compared to those of CV-l2, PC-6 and ST-36.

• Journal of Haehwa Medicine
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• v.12 no.1
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• pp.147-168
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• 2003

This study is about the relationship between the effect of Radiating Qui Therapy on human body and the resulting subjective qui sensation. Patients were between 30 and 50 years of age. n=21 persons received DITI (n=14 patients were provided, n=9 control group) twice examination with Radiating Qui Therapy. First all patients were examined by DITI. After treatment with Radiating Qui Therapy (n=14) both the treated and the control groups were eaxmined again. Radiating Qui Therapy is provided upright position. After Radiating Qui Therapy 92% of the treated group felt a significant qui sensation and 43.5 % felt a warmth at the abdomen and over the whole body. A data of this study show Radiating Qui Therapy has s stimulating effect on human skin temperature. As disease region and Qui sensation are very closely related to each other results strongly suggest that Radiating Qui Therapy could be used as a treatment for a several disease.

• The Korean Journal of Zoology
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• v.39 no.2
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• pp.182-189
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• 1996

It has been known that spermatozoa should obtain their fertilizing ability through capacitation and acrosome reaction, and that in these processes of fertilization, Ca2+ platys an important role for their conjugation. Therefore the present study has been designed in order to clarify the effect of fluctuation of the media Ca2+ level and the intracellular concentration of the spermatozoa on the acrosomes. During the incubation of spermatozoa, a considerable fluctuation in the media Ca2+ level has been observed after the BSA administration and the media concentration of Ca2+. It is deduced that these fluctuation rates may have an effect on the acrosome reaction. The fluctuation of K+ flux has been observed in accordance with the incubation period over time, and it's concentration seems to be closely related with the acrosomal reaction. The respiratory exchange rate (RERI of the spermatozoa is kept more regular in the BSA and Cacl2 administration groups than the non-administration group. Based on the experimental findings, it is possible to deduce a hypothesis from these findings that physiological activities of the acrosome reaction are not functionally related to the media Ca2+ level and the intracellular influx of Ca2+ concentration, although Ca2+ platys an important role as a stimulating factor in the acrosome reaction.

• Preventive Nutrition and Food Science
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• v.19 no.4
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• pp.367-372
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• 2014

Caffeine is widely consumed and well known for stimulating the central nervous system. When developing new foods and beverages that contain caffeine, it is important to explore the potential synergistic effects of consuming amino acids and other food ingredients with caffeine on humans. Given the physiological pathways affected by the amino acid ornithine, consumption of ornithine with caffeine may have synergistic effects. The purpose of the present study was to examine the effect of consuming caffeine with ornithine in humans. The study used a randomized, placebo-controlled, double-blinded crossover design. The subjects were all healthy office workers who ingested the placebo, 100 mg caffeine, or 100 mg caffeine plus 200 mg ornithine in the morning and completed questionnaires about their mood. Office workers who consumed the combination of caffeine and ornithine had higher mood ratings 8 h after consumption than office workers who consumed caffeine alone. The results of the present study suggest that there is a unique synergistic effect between caffeine and ornithine on the mood of healthy office workers and that ornithine may potentiate the effects of caffeine.

• Journal of Pharmacopuncture
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• v.15 no.1
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• pp.7-11
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• 2012

Aim: Historically, mineral compound herbal medicines have long been used in treatments of immune-related diseases in Korea, China and other Asian countries. In this study, we investigated the anti-inflammatory effect of egg white combined with chalcanthite (IS4) on lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. Methods: RAW 264.7 cells cultured with LPS and various concentrations of IS4 were analyzed to determine the production of pro-inflammatory cytokines and mediators by using enzyme-linked immune sorbent assays (ELISAs). Results: IS4 concentration inhibited the production of interleukin-1beta (IL-$1{\beta}$), interleukin-6 (IL-6), and granulocyte-macrophage colony-stimulating factor (GM-CSF) induced by LPS. IS4 at high concentrations (25 and 50 ${\mu}g/ml$) inhibited, in concentration-dependent manner, the expression of tumor necrosis factor-alpha (TNF-${\alpha}$) stimulated by LPS. Conclusion: IS4 has shown an anti-inflammatory effect in RAW 264.7 cells.