• Title/Summary/Keyword: step

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Simplification of One Step Immunotech AFP Test (AFP 검사방법 단축에 관한 고찰)

  • Moon, Ki Choon;Kwon, Won Hyun;Kim, Jung In;Lee, In Won
    • The Korean Journal of Nuclear Medicine Technology
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    • v.17 no.1
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    • pp.80-84
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    • 2013
  • Purpose: The Immunotech AFP is a widely used test in 14 hospitals(RIA QC establishments: 46) as a liver tumor marker. Normally, the test takes 45 minutes including complicated 2 step method. We evaluated the possibility of 1 step method and suitable test time. Materials and Methods: Samples of 31 patients in SNUBH were used as subject. We evaluated the sensitivity, intra and inter assay precision, recovery rate, linearity between 1 step and 2 step method (45 min. and 60 min.). Results: Both of 45 minutes and 60 minutes test showed 0.1 ng/mL sensitivity. In 45 minutes test, the intra assay coefficients of variation were 3.05%, 3.43%, 1.68%. Also, inter assay coefficients of variation were 3.91%, 2.38%, 0.82%. In 60 minutes test, the intra assay were 5.00%, 3.69%, 1.97%, inter assay were 3.14%, 3.71%, 1.85%.The correlation coefficient of each 2 step and 1 step (45 min.), 2 step and 1 step(60 min.), 1 step (45 min.) and 1 step (60 min.) were y=0.9293x+2.7356 ($R^{2}=0.9999$), y=0.9193x+4.1002 ($R^{2}=0.9993$), y=0.9894x+1.3805 ($R^{2}=0.9997$). Conclusion: Compared 1step method to 2 step method, both method showed very reasonable precision, recovery rate and correlation coefficient. Also, 1 step method(45 min.) of correlation coefficient ($R^2$) was 0.999. We suggest that 1 step method test can reduce the test time and is useful for AFP test.

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A Study on Applicability of API-581 and Methodology for Consequence Analysis in High-Pressure Toxic Gas Facilities (고압 독성가스시설에서 API-581 적용성 및 사고결과 분석방법에 관한 연구)

  • Jang, Seo-Il;Kim, Youngran;Park, Kyoshik;Shin, Dongil;Kim, Tae-Ok
    • Journal of the Korean Institute of Gas
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    • v.18 no.4
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    • pp.76-85
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    • 2014
  • To establish the necessary safety technology in high-pressure toxic gas facilities, especially for the corrosion, which is the main causes of toxic gas accident, this study adopts and investigates the API-581 procedures developed by the American Petroleum Institute (API). And the applicability of the 8-step analytical procedures of consequence analysis in API-581 is discussed, and a method for consequence analysis in high-pressure toxic gas facilities is suggested. Based on the discussion and results, the analytical procedure is simplified as the 6 steps in total for the effective application to high-pressure toxic gas facilities: Step 1 (determination of representative material), Step 5 (determination of release type), Step 6 (determination of phase of fluid), and Step 8 (estimation of damage range) are not applied: Step 3 (estimation of total amount of release) is applied only for the inventory group concept; Step 4 (estimation of release rate) only for the gas release rate; and all of Step 2 (selection of release hole size) and Step 7 (evaluation of post-release response) are applied. In the proposed method, the generally applicable method of CCPS is adopted as alternative method for Steps 5 and 8.

Design of Daily Training Protocol for Field Crews Wearing Chemical Protective Clothing for Firefighting and Analysis of Activity (소방용 화학보호복 착용 현장대원의 일상 훈련용 프로토콜 설계 및 활동성 분석)

  • Kim, Si-Kuk;Lim, Woo-Sub;Hong, SungChul
    • Fire Science and Engineering
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    • v.32 no.4
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    • pp.110-121
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    • 2018
  • The present article is concerned with a study on the daily training protocol for field crews wearing chemical protection clothing for firefighting and the analysis of activity. To improve coping ability of & secure safety for firefighting crews initially incorporated in the fields of chemical accident & chemical terror, 10 steps in total of daily training protocol have been designed. The designed protocol is largely composed of the extensive activity protocol for daily adaptation of firefighting chemical protection clothing (steps 1, 2, 6, 7 & 9), the precision operation protocol utilizing hands (steps 3, 4 & 5), and the protocol requiring strong physical burdens (steps 8 & 10). According to the measurement results for activity as a result of the protocol, the average maximum heart rate upon wearing the firefighting chemical protection clothing was shown to increase by step 1 20.32%, step 2 18.69%, step 3 25.23%, step 4 34.77%, step 5 27.44%, step 6 30.24%, step 7 25.33%, step 8 22.25%, step 9 22.80% and step 10 20.85% compared with the time of not wearing them. The average maximum breathing rate was shown to increase by step 3 1.92%, step 4 4.11%, step 5 1.24%, step 6 3.95%, step 7 0.93%, step 8 10.23%, step 9 3.36% and step 10 15.10%, except for steps 1 & 2.

A COMPARISON OF APICAL SEAL FOLLOWING "STEP-DOWN/BALANCED FORCE" AND "STEP-DOWN/STEP-BACK" ROOT CANAL SHAPING (Balanced Force와 Step-Back 근관성형후 치근단 폐쇄효과의 비교연구)

  • Lee, Yun-Hee;Kim, Jong-Hwa;Son, Ho-Hyun;Lee, Kwang-Won
    • Restorative Dentistry and Endodontics
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    • v.20 no.2
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    • pp.780-788
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    • 1995
  • The purpose of this study was to compare the apical seal following root canal shaping by different methods. From fourty extracted mandibular 1st and 2nd molars, fourty mesial roots whose canals have some degree of curvature were selected. The mesiobuccal root portion including mesiobuccal portion of a crown was sectioned in each molar. After access cavity preparation for the mesiobuccal canal, working length was determined with # 10 K-file. The sectioned roots were implanted in acrylic resin block and randomly divided into four groups. The canals of group I were shaped by step-down/balanced force, group II by stepdown/step-back, group III by step-back and group IV by conventional method. All of the shaped canals were obturated by Thermafil method and access cavities were filled with IRM. The roots were removed from acrylic resin block and placed in 100 % humidity for 7days. Except the root surfaces of apical 2mm, the root surfaces were nail-varnished 3 times. After the roots were placed in 700 torr vacuum pressure for 15 minutes, they were immersed in 2% methylene blue solution for 4 days. Nail varnishes were removed with acetone. After that, the roots were decalcified in 5 % nitric acid and dehydrated with alcohol series. Transparent specimens were made by methyl salicylate and the quality of apical seal was assessed by measuring the leakage linearly. The results were as follows. 1. The leakage in canals shaped by step-down/balanced force method was significantly less than that in canals shaped by step-back method(P<0.05) and was less but not statistically than that in canals shaped by step-down/step-back method (P>0.05). 2. The leakage in canals shaped by step-down/step-back method was less than that in canals shaped by step-back method, but there was no statistical significance(P>0.05). 3. The leakage in canals shaped by conventional method was significantly more than that in canals shaped by step-down/balanced force, step-down/step-back and step-back method (P<0.05).

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Comparative Analysis of Callus Induction and Plant Regeneration Rates Using One-step and Two-step Cultures for Rice Anther Cultivation (벼 약배양 1단계 및 2단계 배양을 이용한 캘러스 유도 및 식물 재부화율 비교 분석)

  • Park, Young-hie
    • Journal of Life Science
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    • v.31 no.4
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    • pp.385-388
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    • 2021
  • Anther cultivation for crop breeding is a method of rapid production of homozygosities by greatly reducing the time required for at least six generations to develop new varieties using conventional breeding methods. This technique of producing anther culture provides an opportunity to obtain more green plants from a methodological point of view, and the techniques that save time and effort in anther culture are also important because they increase the efficiency of culture. This study compared the callus induction rate and green plant regeneration rate of a one-step and a two-step culture that differ in their culture media and culture methods. One-step culture allows callus induction and plant regeneration in one medium, whereas two-step culture requires induction and plant regeneration in two different media. In this study, we compared the callus induction and plant regeneration rates of rice anthers as one-step and two-step cultures. The callus formation rate was 13.0% for one-step cultures and 8.6% for two-step cultures, so the rate was 4.4% higher for one-step cultures than for two-step cultures. The plant regeneration rate was 1.0% in one-step cultures and 3.0% in two-step cultures, so the regeneration rate was three times higher for the two-step cultures than for one-step cultures. This suggests that the two-step cultures are more efficient than the one-step cultures for haploid production.

Organic field-effect transistors with step-edge structure

  • Kudo, Kazuhiro
    • 한국정보디스플레이학회:학술대회논문집
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    • 2008.10a
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    • pp.91-93
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    • 2008
  • The organic field-effect transistors with step-edge structure were fabricated. Source and drain electrodes were obliquely deposited by vacuum evaporation. The step-edge of the gate electrode serve as a shadow mask, and the short channel is formed at the step-edge. The excellent device performances were obtained.

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Analysis on the Relationship between Each of the Steps in the Complex Shopping Mall Development (복합쇼핑몰 개발과정에서 각 사업단계간의 관련성 분석)

  • Lee, Chan-Ho
    • Journal of Digital Convergence
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    • v.13 no.8
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    • pp.83-89
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    • 2015
  • In the process of complex shopping mall development, all the steps (business planning step, pre-sale & completion step, management & operations step) head towards a consistent ultimate goal in an overall business perspective. In this study, we analyze using a structural equation model if an appropriate relations between each of the steps are formed to achieve the ultimate goal. In this study, we find a positive relationship between business planning step and pre-sale & completion step, and also find that for success pre-sale & completion, a faithful business plan is necessary. But we find no statistically significant relationship under significant level 0.05 among business planning step and management & operations step and the level of success, pre-sale & completion step and management & operations step and the level of success, management & operations step and the level of success. This suggests that each of the steps does not form a close relationship to achieve the consistent goal in the complex shopping mall development and each one is doing a short-sighted work for its own profit.

A Study on the Out-of-Step Detection Algorithm using Time Variation of Complex Power-Part II : Out-of-Step Detection Algorithm using a Trajectory of Complex Power (복소전력의 변화율을 이용한 동기탈조 검출 알고리즘에 관한 연구-Part II: 복소전력의 궤적 변화를 이용한 동기탈조 검출 알고리즘)

  • Kim Chul-Hwan;Heo Jeong-Yong;Kwon O-Sang
    • The Transactions of the Korean Institute of Electrical Engineers A
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    • v.54 no.5
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    • pp.217-225
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    • 2005
  • In a power system, an out-of-step condition causes a variety of risk such as serious damage to system elements, tripping of loads and generators, mal-operation of relays, etc. Therefore, it is very important to detect the out-of-step condition and take a proper measure. Several out-of-step detection methods have been employed in relays until now. Most common method used for an out-of-step detection is based on the transition time through the blocking impedance area in R-X diagram. Also, the R-R dot out-of-step relay, the out-of-step prediction method and the adaptive out-of-step relay using the equal area criterion (EAC) and Global Positioning Satellite (GPS) technology have been developed. This paper presents the out-of-step detection algorithm using the time variation of the complex power. The complex power is calculated and the mechanical power of the generator is estimated by using the electrical power, and then the out-of-step detection algorithm which is based on the complex power and the estimated mechanical power, is presented. This algorithm may detect the instant when the generator angle passes the Unstable Equilibrium Point (UEP). The proposed out-of-step algorithm is verified and tested by using Alternative Transient Program/Electromagnetic Transient Program (ATP/EMTP) MODELS.

Effect of Step-up and Step-down Hyperthermia on Skin of Mice (온열요법시 온도변화가 정상조직에 미치는 영향)

  • Choi, Ihl-Bohng;Kim, Choon-Yul;Bahk, Yong-Whee
    • Radiation Oncology Journal
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    • v.6 no.2
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    • pp.155-161
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    • 1988
  • The usefulness of hypertermia for cancer therapy have well been established. The purpose of the present investigation was to ascess the effect of step-up $(42^{\circ}{\rightarrow}44^{\circ}C$ sequence) and step-down $(44^{\circ}{\rightarrow}42^{\circ}C$ sequence) heating on the skin of the hind foot of the mouse. Hyperthermic treatments were given by immersion the hind foot of the mouse in circulating water baths. Skin response was studied by the leg reaction, which was scored according to a numerical scoring system proposed by Urano et al (1980). The results were as follows 1. The skin damage of $44^{\circ}C$ control group was more severe than $42^{\circ}C$ control group (P<0.05), except for 15 min. heating group. 2. The Skin damage of step-down group was more severe than step-up group (P<0.05). 3. The skin damage of $44^{\circ}C$ control group was more severe than step-up group when there is no difference in $44^{\circ}C$ heating time of step-up group from $44^{\circ}C$ control group (P<0.05). 4. In step-down group, the skin damage was more severe than $44^{\circ}C$ control group after preheating 45 min at $44^{\circ}C$ (P<0.05). Therefore, the above findings suggest the normal tissue damage by step-up heating was correlated with heating time of post step-up. The dropping of heating temperature in late phase had more severe damage of the skin than that in early phase during hyperthermia, and so contineous control of satisfactory temperature should be considered as the one of the most important factor for prognosis, complications of clinical hyperthermia

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A Stduy on the Development of XML Schemata and STEP Model for Sharing Construction Drawings Information (건설도면정보 공유를 위한 XML 스키마 개발 및 STEP 연계기술에 관한 연구)

  • Kim, In-Han;Choi, Jung-Sik;Jo, Chan-Won
    • The Journal of Society for e-Business Studies
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    • v.9 no.3
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    • pp.57-77
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    • 2004
  • The main purpose of this study is to develop XML schemata and related STEP model for sharing construction drawings information. To achieve this purpose, the authors have developed a drawing information model based on STEP/AP202, the data searching mechanism based on STEP, and XML schemata for sharing and exchanging information between vector data and non-shape attribute information. Finally, the authors have suggested the way of sharing drawing information through linked STEP data and a XML schema using test cases of construction material information and code checking. The study shows a way of optimized managing and sharing construction information through the drawing information and external data for the whole building life-cycle, from early design stage to the construction stage.

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