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Psychopharmacological Profile of the Water Extract of Gardenia jasminoides and Its Constituents, Genipin and Geniposide, in Mice

  • Choi, Ji-Young;Pena, Ike Dela;Choi, Jong-Hyun;Yoon, Seo-Young;Yim, Dong-Sool;Lee, Yong-Soo;Ko, Kwang-Ho;Shin, Chan-Young;Ryu, Jong-Hoon;Kim, Won-Ki;Cheong, Jae-Hoon
    • Biomolecules & Therapeutics
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    • v.16 no.2
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    • pp.118-125
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    • 2008
  • Gardenia jasminoides (G. jasminoides) is traditionally used to treat insomnia, jaundice, emotional disorders, hepatic disease, and inflammatory disease. Previously, we found that geniposide and the water extract of G. jasminoides increased $Cl^-$ influx in neuroblastoma. Here we examined the sychopharmacological activities of G. jasminoides and its constituents. G. jasminoides extract was orally administered at 100 and 200 mg/kg, and genipin and geniposide were intraperitoneally injected at 2, 10, and 20 mg/kg. G. jasminoides extract (200 mg/kg) significantly decreased total open field activity but increased rearing activity in the center of the open field, suggesting an increase in exploratory activity. Genipin and geniposide did not change open field activity, but geniposide (20 mg/kg) increased rearing activity in the central area. The extract (200 mg/kg) significantly decreased rotarod and wire-balancing activity, but genipin and geniposide did not. No compounds influenced thiopental-induced sleeping or electroshock-induced seizures. The extract (200 mg/kg) significantly increased staying time in the open arms of the elevated plus maze and the entry ratio into the open arms, and geniposide (20 mg/kg) also increased open arm entry. Electroshock stress decreased open arm activity, but the extract and geniposide (20 mg/kg) significantly reversed that effect. This results indicate that G. jasminoides extract and geniposide alleviated anxiety with greater efficacy in stressed animals than normal animals.

An Analysis on the Re-visitation Choice of Rural Leisure - Focused on Buraemi, Daraengi, Byucgari region - (농촌여가 시장의 재방문 선택요인 분석 -부래미, 다랭이, 볏가리지역을 대상으로-)

  • Yun, Hee-Jeong;Im, Seung-Bin
    • Journal of Korean Society of Rural Planning
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    • v.14 no.2
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    • pp.33-42
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    • 2008
  • Recently, rural leisure by urban dwellers has been recognized as a catalyst for regional development or restoration. The federal government implemented several regional planning policies attempting to address this phenomenon in the late nineties. However, most of these policies focused on supply-centered planning, which caused a diverse set of problems relating to the sustainability and economic validity of the planning. Instead, this study focuses on the re-visitation one of the demand variables, with the intention of analyzing the character of rural leisure demand and its re-visitation choice attributes. For these reasons, this study investigates the character of current rural leisure demand, and develops functional equations about urban people who visit rural areas, using logit model. The results of this study can be summarized as follow: Urban people are visiting rural areas from nearby cities or metropolitan areas that are within 3 hours driving distance, and over 80% of rural visitors are one-day visitors. Therefore, most of their visitation activities should be understood as rural leisure, including rural tourism. In addition, the likelihood of the rural tourist to make a return visit is influenced by their transportation means, product purchasing, staying period and travel time. The results of such rural leisure demand can provide information for regional planning strategies, such as selection of target market, type of market segments, improvement of recognition level, activity program price, facility and space planning, produce sale and connection with tour site.

Study on the Korean Food Selection Practices by Importance and Satisfaction among Korean Students Attending International Schools (외국인학교 한국 학생의 한식선택 시 중요도 및 만족도 조사)

  • Kim, Min Jung;Hong, Jinim;Jeong, Hee Sun
    • Journal of the East Asian Society of Dietary Life
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    • v.23 no.4
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    • pp.391-402
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    • 2013
  • The purpose of this study is to understand the characteristics and improvements of Korean foods by using the ISA (Importance Satisfaction Analysis) targeting Korean students in international schools in the Seoul Metropolitan area. It also analyzes the difference in the importance and satisfaction of Korean foods, and to provide basic data for developing various healthy diets which are suitable for target students. Target groups are 7 to 12 graders which consist of 62 male students and 42 female students, and most of them had lived in the United States with duration of staying abroad from 1 year to less than 3 years and duration of attending schools from 1 year to less than 2 years. Most of their family structures are the nuclear family, and most of their fathers work in management positions and mothers are mostly full-time housewives. The most favored and consumed food is fruits and the least favored is seaweeds. Perceptions regarding Korean foods are mainly positive and more female students than male students consider Korean foods as well-being foods. The important factor for choosing Korean food is the flavor, and the highest satisfaction lies in the cleanliness of food and tableware, and food temperatures appear to be less important than other factors regarding both importance and satisfaction aspects. The flavor turns out to be the most influential when consuming Korean foods, and information on Korean foods is mostly acquired from advices of those around and through words-of-mouth, and many comments point out that the levels of sanitation should be improved. The result of ISA regarding determinant factors in choosing Korean foods by Korean students in international schools shows that efforts for aggressive improvements should be made in areas for 'the amount of food', 'the price of food', and 'the curiosity on food'.

Developing Students' Self-Directed Camp Programs for Gifted Students (학생 주도적 영재 캠프 프로그램 개발)

  • Lee, Kyung-Sook
    • Journal of Gifted/Talented Education
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    • v.21 no.4
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    • pp.907-925
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    • 2011
  • This study is a report about the two summer camps of 2009 and 2010, which were held by some gifted classes of Liberal Arts areas in Chungnam Province. The students' self- directed methods, making an own project topic and an outline plan for that by students themselves before the camp, raised up the students' satisfaction of the camp effectively. Staying with their peer students and teachers for 3 days gave the gifted students a chance for relationship, self-confidence, and self-sufficiency. These joint summer camps provided the students with cognitive development, motivations and a chance to meet other gifted students. Teachers' preparation for the camp, their concrete feedback to each student's project, and students' time spending on one's own camp project were correlated with the students' satisfaction of the camp program. Experience of teacher training in gifted education made significant differences in understanding gifted students and expectations of students' social and emotional development throughout and after the camp.

Numerical Analysis of Combustion and Heat Transfer of Domestic Gas Boiler Equipped with 2-stage Heat Exchanger (수치해법을 이용한 2단 열교환기 장착 가정용 보일러 연소실의 연소 및 열전달 특성 해석)

  • Kang, Seung-Kyu;Choi, Kyoung-Suhk;Kwon, Jeong-Rack
    • Journal of the Korean Institute of Gas
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    • v.14 no.5
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    • pp.1-6
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    • 2010
  • In this work, a numerical investigation is performed for the combustion chamber of domestic gas boiler with 1-stage and 2-stage heat exchangers. The fluid flow and heat transfer performance is simulated with a structure change of heat exchanger. The numerical solution shows that the heat transfer of the 2-stage heat exchanger is about 24% higher than that of the 1-stage heat exchanger, while the pressure loss of the 2-stage heat exchanger increases. The temperature of combustion chamber with 2-stage heat exchanger is lower than that of 1-stage. This effect reduces thermal NOx with decrease of high temperature staying time of the combustion gas.

Implementation of SLA Management System for QoS Guarantee in Cloud Computing Environment (클라우드 환경에서 QoS 보장을 위한 SLA 관리시스템 구현)

  • Yoon, Ka-Ram;Lee, Bong-Hwan
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.17 no.2
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    • pp.302-308
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    • 2013
  • Internet is becoming more common with increasing cloud services have been spreading rapidly. A SLA is agreements between service providers and customers of service providers is how to ensure quality of service. SLA in cloud computing environments from the perspective of the IT service providers to customer satisfaction increase for service quality, it will need to differentiate between competing carriers QoS guarantees with SLA is a very important factor. However, the study of SLA in the cloud is staying in its infancy. In this paper, SLA indices for cloud services defining and use them SLA Management System for QoS guarantee has been implemented. The proposed system using monitoring-based migration policy an open source-based cloud computing platform which Cluster Nodes load distribution of virtual machines assigned to their availability, response time, throughput analysis of what affects and is compared with existing cloud.

A Study on Furniture Making Program Development for Children's Designing Creativity (어린이 디자인 창의성 개발을 위한 D.I.Y 가구 만들기 프로그램 개발에 관한 연구)

  • Kim, Young Joo
    • Journal of the Korea Furniture Society
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    • v.26 no.3
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    • pp.187-195
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    • 2015
  • School activities which are opened after-school or during a vacation have been social issues as our society is nuclearized and both parents are working, so that elementary school students and middle school students are less taken care of and less concerned by their parents. It is regrettable that students are spending too much time on private academies in the situation where they cannot help but staying alone after school and where frantic fever of private education pervades their lives. For the sake of those students, the Ministry of Education announced, "Each school can open its after-school programs or vacation programs based on students and their parents' demands making it a rule of a student's voluntary participation. After school programs for elementary and middle school students are operated by local communities providing extra courses or programs in addition to regular classes. Those programs are paid by participants or supported by financial aids in order to decrease parents' burdens of costs of private education and to reduce educational gaps between rich and poor children or between the regions. After school programs are either curricular or non-curricular educational activities with students' voluntary participation, and the programs are meant to supplement and strengthen the role of public school education. Non-curricular courses that consist of various programs, in particular, are receiving good reputations by students and parents. Therefore, this study develops and operates "children's making D.I.Y. furniture" program that is one of non-curricular courses and an activity-oriented art program for children to improve their designing creativity and to help them experience their future jobs in advance. The purpose of this study is to analyze advantages and disadvantages of the program using survey and assessment methods and to find out a developmental direction focused on future-oriented and specialized educational programs for children.

A Study on the Digital Architectural Space's Characteristic of Expression Based on the Traditional Architecture Properties - Focused on the Immateriality Characteristics - (전통 건축 공간 특성으로 본 디지털 건축 공간의 표현특성에 관한 연구 - 비물질적 특성을 중심으로 -)

  • Lee, Joon-Ho
    • Korean Institute of Interior Design Journal
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    • v.23 no.5
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    • pp.51-57
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    • 2014
  • In the early 20st century, created distrust on the mechanistic and dualistic view based on the world of Descartes and Newton. As the features of this new science cannot be explained by the existing Western philosophy but can be explained by the thinking system immanent in the Oriental traditional thought, many scientists and philosophers are concentrating their interests on the Oriental philosophy. In addition, some have been making efforts to find solutions needed for a new paradigm from the thinking system of the Orient. A variety of discussions have also been raised in connection with architecture due to this philosophical change. It has now become possible to conduct free creative acts, staying away from physical limitations, including gravity by diversified simulations through a computer. This physical liberation in turn has caused new changes to the spatial concept of architecture, thereby granting the freedom of the expression that could not be even imagined before and opening a possibility of new architecture and space. At the same time, the digital space architecture actively accommodating this technology is generating a phenomenon that the existing physical and realistic things are rapidly being changed gradually to immaterial and unrealistic ones. This study has analyzed the properties of digital architectural space as the immateriality of our traditional architectural space. The results are as follows: It can be seen that the immaterial features exhibited in the digital architectural space and the traditional architectural one are not just interconnected with specific features, but they are correlated to all immaterial features. Thus, immateriality that are common in the traditional and digital architectural spaces is complementary organic, which is contained in the ambiguity of boundary between other spaces. It is regarded to the architecture as a living things in space diversity based on ideological similarities.

A Study on the Punggi (風旗), Meteorological Instrument Made in the Joseon Dynasty (조선시대의 바람 관측기기인 풍기(風旗)의 연구)

  • Jeon, Jun Hyeok;Lee, Yong-Sam
    • Atmosphere
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    • v.23 no.1
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    • pp.47-61
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    • 2013
  • The Punggi (風旗) is one of the meteorological instruments made in the Joseon Dynasty (朝鮮王朝). Its purpose was to observe the direction of the wind. It is estimated that it started its operation in the $16^{th}$ century at least. But it does not remain in a perfect form, like the Chugugi (測雨器) and the Supyo (水標). The Punggi (風旗) can only be found at old document data, while the stone used to build the Punggi still remains. Since the stone had been named as the Punggi-dae (風旗臺) by 和田雄治 (1917), the name has not been changed until now. The Punggi is currently located in the Gyeongbok-gung (景福宮) and the Changgyeong-gung (昌慶宮). Meantime, there have been several transfers of its position. However, 和田雄治 (1917)'s paper and the "每日新報" (Maeil-Sinbo, 1929) articles have provided new clues. Also, the word 'Hupungso (候風所)' was found in the "朝鮮王朝實錄" (The annals of the Joseon Dynasty) and the "承政院日記" (Daily records of royal secretariat of Joseon dynasty). A designed harbor where the ship was staying was usually considered a special section for wind observations. It is assumed that the Hupungso was in most of the harbors at that time. This paper assumes the Punggi and the Hupungso had a lot of interest in wind observations in the Joseon Dynasty. In this study, we'll look for contained information about the Punggi and the viewpoints about wind during the Joseon Dynasty.

A Study on Ik-mo Lee's Yeonhaengrok (이익모의 병진연행록에 관한 연구)

  • Roh Ki-Chun
    • Journal of Korean Library and Information Science Society
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    • v.36 no.3
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    • pp.213-231
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    • 2005
  • Yeonhaengrok is a document recorded by one member of the envoy sent to the China from 17 to 19 century. Ik-mo Lee, a member of the envoy, wrote a full explanation of the visit from Nov. 24 1796 to Mar. 7 1797 in his writing $\ulcorner$Byongjin Yeonhaengrok${\lrcorner}$. $\ulcorner$Byongjin Yeonhaengrok${\lrcorner}$, which is omitted in the complete collection of $\ulcorner$Yeonhaengrok${\lrcorner}$, has been newly found at the Family of Suwon Baek's house locating at the Sanggum Vil., Yongsan Town, Jangheung County of Chonnam Province. $\ulcorner$Byongjin Yeonhaengrok${\lrcorner}$ contains an historical meaning that it is an official record of the official envoy that was sent first after the Injong's enthronement in China. This study observed the bibliographical features of $\ulcorner$Byongjin Yeonhaengrok${\lrcorner}$, the time of the transcription, the progress of receiving by the Suwon Baek family. And certified the details of the Byongjin envoy, going and returning between Hanyang and Beijing, staying schedules of the envoy in Beijing.

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