• Title/Summary/Keyword: statistical treatment

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On Detecting the Best Treatment

  • Kim, Woo-Chul
    • Journal of the Korean Statistical Society
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    • v.17 no.2
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    • pp.81-92
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    • 1988
  • We observe independent random variable $Y_i \sim N(\theta_i,1), i=1,2,\cdots,k$, and we are interested in detecting the treatment with the largest $\theta_i$. We consider a procedure which infers $\theta_{(k)} \geq max\theta_i (i\neq(k))$ whenever $Y_{(k)} \geq maxY_i+C (i\neq(k))$. The maximum probability of a false inference is found, and it is shown that the inference can be made with the two-sample one-sided critical value for the usual error levels. The result also holds in the case of common unknown variance.

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A Modified Chen-Wolfe Procedure for Comparing Umbrella Pattern Treatment Effects with a Control in a One-way Layout

  • Lim, Dong-Hoon;Kim, Soo-Taek;Park, Joong-Yang
    • Communications for Statistical Applications and Methods
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    • v.3 no.1
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    • pp.145-153
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    • 1996
  • Nonparametric tests for comparing umbrella pattern treatment effects with a control in a one-way layout were studied in Chen and Wolfe (1993). In this paper we propose a modification that improves the power of the Chen-Wolfe test. The results of a Monte Carlo power study are discussed.

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Bootstrap Confidence Interval of Treatment Effect for Censored Data

  • Hyun Jong KIM;Sang Gue PARK
    • Communications for Statistical Applications and Methods
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    • v.4 no.3
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    • pp.917-927
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    • 1997
  • Consider the confidence interval estimators of treatment effect when some of data to be analyzed are randomly censored, assuming two-sample location-shift model. Recently proposed PARK and PARK(1995) Estimators is discussed and a bootstrap estimator is proposed. This estimator is compared with other well-known estimators throught the simulation studies and recommendations about the use are made.

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Persisting Effects of Acupuncture Method for Chronic Tension-type Headache;A Randomized Controlled Trial (만성 긴장성 두통 환자의 침치료 지속효과에 대한 임상연구)

  • Kwak, Byung-Min;Kim, Min-Jeong;Kim, Yeon-Mi;Lee, Jae-Min;Park, Yang-Chun;Jo, Jeong-Hyo;Jeong, In-Choel;Kang, Wee-Chang;Lee, Sang-Bong;Choi, Sun-Mi;Hong, Kwon-Eui
    • Journal of Acupuncture Research
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    • v.25 no.2
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    • pp.165-177
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    • 2008
  • Objectives : Headache is one of the most common symptom in primary medical care. The purpose of this research is to examine persisting effects of acupuncture treatment for CTTH. Methods : In this randomized, single blind, placebo-controlled study, we compared active acupuncture with sham acupuncture method for the treatment of chronic tension-type headache. Volunteers who satisfied the requirements were enrolled in study. Evaluation of CTTH was measured by VAS, and Headache Disability Inventory(HDI), Six point Likert Scale, Algometer score(Rt, Lt) before and after treatments. Results : 32 subjects finished study. There were no difference between two group on age, sex, weight, height, blood pressure, pulse, respiratory rate, differentiation of symptoms, surmise of treatment. In change of VAS, after treatment decreased than before treatment in two group, but there were no statistical significance compared with two group and time. In change of HDI(Total score, Emotional score, Functional score) and Six point Likert scale, after treatment decreased than before treatment in two group, but there were no statistical significance compared with two group and time. In change of two sides Algometer score, after treatment increased than before treatment in two group, and Lt algometer score was statistical significance compared with two group(p<0.001). And both sides Algometer score, threr were statistical significance compared with time. Conclusions : Acupuncture treatment has persisting effects that improve the symptoms and decrease the temporal muscle tenderness in patient with chronic tension-type headache.

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Regression discontinuity for survival data

  • Youngjoo Cho
    • Communications for Statistical Applications and Methods
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    • v.31 no.1
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    • pp.155-178
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    • 2024
  • Regression discontinuity (RD) design is one of the most widely used methods in causal inference for estimation of treatment effect when the treatment is created by a cutpoint from the covariate of interest. There has been little attention to RD design, although it provides a very useful tool for analysis of treatment effect for censored data. In this paper, we define the causal effect for survival function in RD design when the treatment is assigned deterministically by the covariate of interest. We propose estimators of this causal effect for survival data by using transformation, which leads unbiased estimator of the survival function with local linear regression. Simulation studies show the validity of our approach. We also illustrate our proposed method using the prostate, lung, colorectal and ovarian (PLCO) dataset.

A Clinical Study on The Effect of Oriental Treatment For Obesity in National Health Services (공공보건의료영역에서 한방 비만치료의 효과)

  • Shin, Min-Seop;Lim, Sung-Taek;Park, Min-Ho;Yuk, Tae-Han
    • Journal of Pharmacopuncture
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    • v.9 no.1
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    • pp.95-101
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    • 2006
  • Objectives : This study was to investigate the effect of National Health Services for obesity patients by oriental medical treatment. Methods : We analyzed 46 obesity patient joined to Oriental Treatment for Obesity in Sunchang Medical Center with BCA(bocy component analysis), after we had treated them with our obesity program. We analyzed changes of BCA during before and after treatment, and analyzed items in BCA are weight(kg), amount of muscle(kg), amount of body fat(kg), body fat rate(%) and BMI(body mass index). Results : 1. Weight, amount of muscle, amount of body fat, body fat rate and BMI were decreased in after treatment, but they didn't have statistical significance. 2. This studies suggest oriental treatment for obesity may be an effective overweigh group(BMI $25{\sim}30$), because it had statistical significance(P<0.05). 3. It appears that oriental treatment for obesity have an effect in National Health Services

Phase II Study on EANI Combined with Hydrochloride Palonosetron for Prevention of Chemotherapy-induced Nausea and Vomiting Following Highly Emetogenic Chemotherapy

  • Xiao, Yang;Liu, Jun;Liu, Yang-Chen;Huang, Xin-En;Guo, Jian-Xong;Wei, Wei
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.9
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    • pp.3951-3954
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    • 2014
  • Objective: To investigate the electronic anti-nausea instrument (EANI) combined with hydrochloride palonosetron for prevention of chemotherapy-induced nausea and vomiting following highly emetogenic chemotherapy. Methods: Patients who received highly emetogenic chemotherapy were randomly assigned to a treatment group (60 patients) treated with EANI combined with hydrochloride palonosetron, and control group (also 60 patients) given only hydrochloride palonosetron. Chemotherapy related nausea and vomiting were observed and recorded in both groups of patients from the start till the end of chemotherapy. Results: Complete control rates of vomiting in treatment and control group were 40%, and 35%, respectively, without any statistical ly significant difference (p>0.05); however the response rates are 95.0%, 78.3%, respectively, with statistical difference (p<0.05). Complete control rates of nausea in treatment and control group were 36.7%, 30%, respectively, without statistical difference (p>0.05); but the response rates are 90.0%, 76.7%, respectively, with statistical difference (p<0.05). Conclusion: EANI combined with hydrochloride palonosetron for prevention of nausea and vomiting induced by chemotherapy could be more effective than hydrochloride palonosetron alone, and can be recommended for use in prevention and treatment of chemotherapy-induced nausea and vomiting following highly emetogenic chemotherapy.

Comparing the Effects of Stability Exercise, ESWT, and Taping for Patients with Myofascial Pain Syndrome of Upper Trapezius (안정화 운동, 체외충격파, 테이핑이 상승모근 근막통증 증후군에 미치는 효과 비교)

  • Lee, Jung-Ho;Hwang, Kyung-Ok;Park, Young-Han
    • The Journal of Korean Physical Therapy
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    • v.24 no.2
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    • pp.82-89
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    • 2012
  • Purpose: In this study, the effects of stability exercise, extracorporeal shock wave therapy, and taping on pain and function in patients with myofascial pain syndrome of upper trapezius were compared. Methods: The subjects were divided into the stability exercise, ESWT and the taping treatment group and the clinical outcomes were evaluated by visual analog scale (VAS), pressure pain threshold (PPT) and a constant-murley scale (CMS) at pre-treatment and post-treatment. Paired t-test and ANOVA was used for statistical analysis. Results: All groups were statistical significance in the change in visual analog scale (p<0.05). The difference between the ESWT group and taping group was statistical significance in the change in pressure pain threshold (p<0.05) except for the taping group. Using the constant-murley scale, the stability exercise group showed a significant decrease in pain, and a significant increase in ROM, ADL, strength, total score of shoulder (p<0.05); however, the ESWT group showed no difference on ADL. In addition, there was no difference in strength for the taping group. The comparison of the effect between the stability exercise group, ESWT group and taping group in CMS showed a statistical significant difference in pain, ADL and ROM (p<0.05). Conclusion: These results indicate that stability exercise, ESWT and taping could be considered an effective and efficient treatment modality for myofascial pain syndrome of upper trapezius.

Computation of Irrigation Interval and Amount as affected by Growing Substrate and Soil Depth Planted with Zoysia japonica in Green Roof during a Dry Summer (여름철 무강우 시 들잔디 옥상녹화 식재지반에 따른 관수주기 및 관수량 산정)

  • Ju, Jin-Hee;Bae, Gyu-Tae;Kim, Won-Tae;Yoon, Yong-Han
    • Journal of Environmental Science International
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    • v.21 no.3
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    • pp.289-296
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    • 2012
  • The purpose of this study was to identify the irrigation intervals and the amount of suitable growing substrate needed to achieve the desired shallow-extensive green roof system during a dry summer in Korea. In terms of treatment, three types (SL, $P_6P_2L_2$, $P_4P_4L_2$) with varying soil mixture ratios and two types (15 cm, 25 cm) with varying soil depths were created. The results have been analyzed after measuring growth and soil water contents. The difference of growth by treatment was significant in terms of green coverage, height, leaf width and photosynthesis. In measurement of chlorophyll content, no difference was detected when measured against soil depth. According to the growth measurement of Zoysia japonica with respect to differing soil mixture ratios in the 15 cm-deep treatment, a statistical difference was detected at the 0.05 significance level in photosynthesis. In case of green coverage, height, chlorophyll content and leaf width, no statistical significance was observed. In case of the 25 cm-deep treatment, a statistical significance was observed in height and photosynthesis. In terms of green coverage, chlorophyll content and leaf width, no statistical significance was detected. In comparisons of soil moisture tension and soil water contents, the irrigation interval and amount were 8 days and 14.9 L in the SL (15 cm) treatment, respectively. The irrigation interval showed for 10 days a 1.3-fold increase, and the irrigation amount was 27.4 L 1.8-fold more than SL (25 cm), respectively. For $P_6P_2L_2$ (15 cm) treatment, the irrigation interval and amount were 12 days and 20.7 L, respectively. However, an irrigation interval under $P_6P_2L_2$ (25 cm) was for 15 days 1.3 times longer than $P_6P_2L_2$ (15 cm), and an irrigation amount of 40 L was 1.9 times more than that under $P_6P_2L_2$ (15 cm). In $P_4P_4L_2$ (15 cm) treatment, it was indicated that the irrigation interval was 15 days, and the irrigation amount was 19.2 L. It was not needed to irrigate for 16 days under $P_4P_4L_2$ (25 cm) treatment during the dry summer and the longest no-rain periods. The irrigation interval and amount under $P_4P_4L_2$ were 1.8-fold and 1.3-fold, respectively, more than SL treatment as affected by soil mixture ratio. Comparatively $P_4P_4L_2$ had more 1.3-fold and 0.9-fold in irrigation interval and amount more than $P_6P_2L_2$. Therefore, it can be noted that different soil depth and soil mixture ratios had a significant effect on the irrigation interval and amount.

Improvement of Operating Efficiency on Advanced Wastewater Plant Using Statistical Approach (고도처리 효율 향상을 위한 통계적 접근)

  • Moon, Kyung-Sook;Min, Kyung-Sub;Kim, Seung-Min;Lee, Chan-Hyung
    • Journal of Environmental Science International
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    • v.17 no.4
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    • pp.405-412
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    • 2008
  • Statistical analysis technique was applied to operating parameters and removal efficiency data sets obtained from advanced wastewater treatment plant during 1 year. Through factor analysis three factors derived varimax rotation were selected each plant. Three components explained 96%, 87% of the total variance of the process, respectively. The components on $A_2O$ Plant were identified in the following order : 1) Shortening the SRT during high-flow period, 2) Keeping biomass high on winter 3) factor was related to DO. On DNR plant, we defined them as follows: factor 1, Prolonged the SRT during high-flow period; factor 2 was related to sludge return; factor 3, Influent BOD during low-DO period. This technique was believed to assist operators in identifying priorities to improve operation efficiency.