• Title/Summary/Keyword: statistical significance

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An Experimental Study on the Effect of Anti-Histamine of the Sungmagalkuntang and Sungmagalkuntang-plus-samultang (승마갈근탕(升麻葛根湯) 및 승마갈근탕합사물탕(升麻葛根湯合四物湯)의 항(抗) Histamine 효과(效果)에 관(關)한 연구(硏究))

  • Kim, Hyun-Ah;Jeong, Ji-Cheon;Pak, Sun-Dong
    • The Journal of Dong Guk Oriental Medicine
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    • v.3
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    • pp.207-222
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    • 1994
  • In order to find out the effect of Anti-Histamine of the Sungmagalkuntang and Sungmagalkuntang-plus-samultang I've investigated the effect of the time to death, the peripheral vascular Pemeability, the amount of secretion of Gastric Juice, the total Acidity of Gastric Juice, the contraction of Intestine Tube by Histamine and the effect of the Skin-Reaction by the decrease of DNCB. These results are following ; 1. The effect of Mice's time to death by Histamine was that the injection group of sungmagalkungtang and the injection group of sungmagalkungtang-plus-samultang both have had the effect of the extention of the time to death, which indicated a statistical significance in comparison with comparative group. 2. The effect of the increased vascular permeability by Histamine was that the injection group of sungmagalkuntang and the injection group of sungmagalkuntang-plus-samultang both have had the effect of the restraint of the increased vascular permeability, which indicated a statistical significance in comparison with comparative group. 3. The effect of the the amount of the secretion of Gastric Juice by Histamine stimulus was that the injection group of sungmagalkuntang-plus-samultang only has had the effect of restraint of the increased of the secretion of Gastric Juice, which indicated a statistical significance in comparison with comparative group. 4. The effect of the change of total Acidity of Gastric Juice by Histamine's stimulus was that the injection group of sungmagalkuntang-plus-samultang only has had the effect of the restraint of the increase of total Acidity of Gastric Juice, which indicated a statistical significance in comparison with comparative group. 5. The effect of the contraction of Intestine Tube by Histamine was that sungmagalkuntang and sungmagalkuntang-plus-samultang both have had the effect of the contraction and the restraint. According to the increase of the density, the effect of the restraint was more clear. But the difference of the effects between two substances had little. 6. The effect of the reaction of skin by the decrease of DNCB was that the injection group of sungmagalkuntang and the injection group of sungmagalkuntang-plus-samultang have had the decreased effect of the Skin-Reaction in comparison with comparative group. sungmagalkuntang-plus-samultang aws more effective. In these results shown above, both sungmagalkuntang and sungmagalkuntang-plus-samultang was shown as more effective one.

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Computation of Irrigation Interval and Amount as affected by Growing Substrate and Soil Depth Planted with Zoysia japonica in Green Roof during a Dry Summer (여름철 무강우 시 들잔디 옥상녹화 식재지반에 따른 관수주기 및 관수량 산정)

  • Ju, Jin-Hee;Bae, Gyu-Tae;Kim, Won-Tae;Yoon, Yong-Han
    • Journal of Environmental Science International
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    • v.21 no.3
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    • pp.289-296
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    • 2012
  • The purpose of this study was to identify the irrigation intervals and the amount of suitable growing substrate needed to achieve the desired shallow-extensive green roof system during a dry summer in Korea. In terms of treatment, three types (SL, $P_6P_2L_2$, $P_4P_4L_2$) with varying soil mixture ratios and two types (15 cm, 25 cm) with varying soil depths were created. The results have been analyzed after measuring growth and soil water contents. The difference of growth by treatment was significant in terms of green coverage, height, leaf width and photosynthesis. In measurement of chlorophyll content, no difference was detected when measured against soil depth. According to the growth measurement of Zoysia japonica with respect to differing soil mixture ratios in the 15 cm-deep treatment, a statistical difference was detected at the 0.05 significance level in photosynthesis. In case of green coverage, height, chlorophyll content and leaf width, no statistical significance was observed. In case of the 25 cm-deep treatment, a statistical significance was observed in height and photosynthesis. In terms of green coverage, chlorophyll content and leaf width, no statistical significance was detected. In comparisons of soil moisture tension and soil water contents, the irrigation interval and amount were 8 days and 14.9 L in the SL (15 cm) treatment, respectively. The irrigation interval showed for 10 days a 1.3-fold increase, and the irrigation amount was 27.4 L 1.8-fold more than SL (25 cm), respectively. For $P_6P_2L_2$ (15 cm) treatment, the irrigation interval and amount were 12 days and 20.7 L, respectively. However, an irrigation interval under $P_6P_2L_2$ (25 cm) was for 15 days 1.3 times longer than $P_6P_2L_2$ (15 cm), and an irrigation amount of 40 L was 1.9 times more than that under $P_6P_2L_2$ (15 cm). In $P_4P_4L_2$ (15 cm) treatment, it was indicated that the irrigation interval was 15 days, and the irrigation amount was 19.2 L. It was not needed to irrigate for 16 days under $P_4P_4L_2$ (25 cm) treatment during the dry summer and the longest no-rain periods. The irrigation interval and amount under $P_4P_4L_2$ were 1.8-fold and 1.3-fold, respectively, more than SL treatment as affected by soil mixture ratio. Comparatively $P_4P_4L_2$ had more 1.3-fold and 0.9-fold in irrigation interval and amount more than $P_6P_2L_2$. Therefore, it can be noted that different soil depth and soil mixture ratios had a significant effect on the irrigation interval and amount.

A Study on the Characteristics according to Sasangin - Targeting the Group of Ordinary Adolescents - (사상인(四象人)의 성격(性格) 특성(特性)에 관(關)한 연구(硏究) -정상(正常) 청소년(靑少年) 집단(集團)을 대상(對象)으로 -)

  • Whang, Man-Ki;Hwang, Ui-Wan;Kim, Jong-Woo
    • Journal of Oriental Neuropsychiatry
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    • v.15 no.2
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    • pp.71-88
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    • 2004
  • Objectives : The aims of this report are to examine the personal characteristics and to determine the different reactions against stress by constitutions. To achieve these goals, the statistical research was adopted. Methods : First of all, the total numbers of 398 middle school students were classified into three constitutions by QSCC II. According to each type of constitutions, both of the KPI Personality Test and Multidimensional Encountering Scale (MES) on how to deal with stress were conducted. Summary of the findings : 1. Based on the findings assessed by the QSCC II test, the constitutional distribution reveals the difference according to genders. In Chi-square test, the girl reveals significantly high (p<0.05) distribution in Soyangin. 2. In Independent T-test regarding KPI personality, the girl reveals high significance (p<0.05) in terms of 'Sociability', 'Responsibility', 'Synchronism' and 'Self-feminity' (or Feminization) while the boy reveals high significance in 'Goal-driven' (p<0.05). 3. In Independent T-test regarding the multidimensional encounter scaling, the girl reveals high significance (p<0.05) in D (expression of emotion). 4. In case of the boy, the Soeumin shows low significance (p<0.05) in 'Leadership' and 'Sociability' compared to the Taeumin or the Soyangin. On the other hand, the Soeumin reveals high significance (p<0.05) in 'Responsibility' and 'Self-control' compared to the Soyangin and additionally, shows high significance (p<0.05) in 'Self-feminity' (or Feminization) compared to the Taeumin or the Soyangin. Furthermore, the Soyangin shows high significance (p<0.05) in 'Self-confidence' compared to the Soeumin or the Taeumin. 5. In case of the girl, the Soyangin reveals high significance in 'Sociability' and 'Self-confidence' compared to the Soeumin or the Taeumin while the Soeumin has high significance in 'Synchronism' compared to the Taeumin or Soyangin. On the other hand, the Soeumin has high significance in terms of 'Responsibility', 'Self-control', and 'Self-feminity' (or Feminization) while showing low significance in 'Flexibility' compared to the Soyangin. 6. For boys, the Soeumin has low significance in 'Sociability' in comparison with both the Soyangin and the Taeumin, whereas for girls, the Soyangin reveals high significance in 'Sociability' in comparison with both the Soeumin and the Taeumin. As per the 'Self-confidence' and 'Responsibility', it has been proved that there is no notable difference between the boy and the girl, but to the contrary, as per the 'Self-confidence', both for the girl and the boy, the Soyangin has high significance (p<0.05) in comparison with the Soeumin and the Taeumin. In addition, in 'Responsibility' side, it is recognized that the Soeumin shows high significance (p<0.05) in comparison with the Soyangin both for boys and girls. Only the difference between genders, as to the 'Self-confidence', is that the Soeumin shows low distribution compared to the Taeumin in the case of boys, while the Taeumin shows low distribution compared to the Soeumin in the case of girls. In 'Self-feminity' (or Feminization), for boys the Soeumin shows high significance in comparison with both the Soeumin and the Taeumin, but to the contrary, for girls the Soeumin shows high significance (p<0.05) only against the Soyangin. 7. In case of boys, as to 'Conformability (compromise)', the Taeumin compared to the Soeumin reveals high significance (p<0.05), while for girls, the Soeumin compared to the Soyangin or the Taeumin reveals high significance (p<0.05). Consequently, it presents that the Soyangin has a tendency not to confirm (compromise) relatively in comparison with other constitutions regardless of the genders. Conclusions : In general, except that it shows some constitutional deviation by genders, the statistical findings of this report agree and comply with the personal characteristics of Sasangin presented by Je-Ma Lee.

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Study to Protocol of PET Acquisition Time for Patient Body Type in PET/CT (PET/CT 검사에서 환자체형에 따른 적정검사 프로토콜에 관한 고찰)

  • Cho, Seok Won;Ham, Joon-Chul;Kang, Chun Goo;Bahn, Young Kag;Lee, Seung Jae;Lim, Han Sang;Lee, Chang-Ho;Park, Hoon-Hee
    • The Korean Journal of Nuclear Medicine Technology
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    • v.17 no.2
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    • pp.72-77
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    • 2013
  • Purpose: Whole-body PET using radiopharmaceutical is one of the imaging study methods for physiological changes of body. High specificity of the PET-CT examination is used to detect an early stages of cancer and metastatic cancer by imaging a physiological changes. During the imaging process, PET image has been characterized by a relatively low image quality due to its low sensitivity and the acquisition of random and scatter coincidences as well as patients figure. Therefore, the image quality as the changes of the acquisition times of patient weight was evaluated in this study. Materials and Methods: Thirty patients who presented to our hospital were enrolled. They were divided to normal, overweight, and obese group using BMI index, respectively. The patients with a liver disease and diabetes were excluded. $^{18}F-FDG$ was administered to the patients as 5.2 MBq per kg. After an hour from an injection, image acquisition was obtained as List mode in a part of liver in 1 bed. SNR (signal-to-noise ratio) of each groups acquisition times were confirmed from the calculated radiation counts and random fractions. The statistical significance of three groups was confirmed through one-way ANOVA test. On the basis of the counts of 2 minutes on normal group, the SNR of overweight group and obese group were compared. Results: The SNR were increased with loger aquisition time in 3 groups. In the condition of same acquisition time, the SNR had a statistical significance (P<0.05). The SNR were decreased to the normal, overweight, and obese, respectively. Liver activity had no significance difference on each group and RF had the significance differences (P<0.05). On the basis of the counts of 2 minutes on normal group, there were no statistical significance in a three minute acquisitions of overweight group and two minute acquisitions of obese group (P=0.150). Conclusion: In this study, the administrated amount of radiation dose did not adjust as the change of the patients weight. Increasing the acquisition time when the administration of the same amount of dose was able to get a good result of SNR. When the Based 2 minute on normal group, if overweight and obese case the increased acquisition time of 3 minute was able to obtain a similar SNR. On the basis of the normal group, the acquisition times of overweight and obese group were increased to 3 minutes per bed and the SNR were similar to the normal group.

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Clinical Significance of Joint Detection of Serum VEGF, SIL-2R and HGF in Patients with Primary Hepatocellular Carcinoma before and after Percutaneous Microwave Coagulation Therapy

  • Chen, Ji-Dong;Xiong, Yan-Qun;Dong, Ke;Luo, Jun;Yue, Lin-Xian;Chen, Qin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.11
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    • pp.4545-4548
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    • 2014
  • Objective: To investigate the changes of serum vascular endothelial growth factor (VEGF), soluble interleukin-2 receptor (SIL-2R) and hepatocyte growth factor (HGF) contents in patients with primary hepatocellular carcinoma (HCC) before and after percutaneous microwave coagulation therapy (PMCT) and determine their clinical significance. Materials and Methods: Fasting venous blood (3 mL) from 81 patients with primary HCC diagnosed by pathology was collected in the mornings 1 day before PMCT, and 1 day, 7 days and 1 month after PMCT, and then the serum was separated and stored in $-70^{\circ}C$. The contents of VEGF, SIL-2R and HGF were detected by enzyme linked immunosorbent assay (ELISA). Results: The serum VEGF, SIL-2R and HGF contents in 81 patients with primary HCC had obviously dynamic changes before and after PMCT. By comparison to 1 day after PMCT with pre-operation, there was no statistical significance regarding VEGF and SIL-2R contents (P>0.05), but HGF content showed significant difference (P<0.01). Compared with pre-operation, VEGF, SIL-2R and HGF contents 7 days and 1 month after PMCT all manifested significant differences (P<0.01). By comparison to 7 days with 1 month after PMCT, there was no statistical significance regarding the VEGF content (P>0.05), whereas SIL-2R and HGF contents showed significant change (P<0.01). Conclusions: The contents of serum VEGF, SIL-2R and HGF have obviously dynamic changes in primary HCC before and after PMCT, and their joint detection is expected to be an effective hematologic evaluation index of PMCT for primary HCC.

Effect of Pain and Shoulder Joint Function on Extracorporeal Shock Wave Therapy of Patients with Frozen Shoulder (체외충격파 치료가 동결견 환자의 통증과 견관절 기능에 미치는 영향)

  • Cho, Nam-Jung;Park, Ji-Whan
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.13 no.2
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    • pp.69-78
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    • 2007
  • Purpose: The purpose of this study was to assess the effectiveness of Extracorporea Shock - Wave Therapy (ESWT) on the pain and improvement of shoulder joint function which is one of the available medical treatment in patients with frozen shoulder. Object and Methods: 26 patients with frozen shoulder, with 26 patients assigned to two groups; a control treatment group (n=12) and a ESWT application group (n=14). In the ESWT application group, the patients received general physical therapy, and then they received ESWT. In the control treatment group, the patients received only general physical therapy. These medical treatments was conducted total 6 time for 3 weeks. To investigate the effectiveness of the treatment after the each group's treatment. Pain was measured by Visual Analogue Scale (VAS) which is divided into 10 ranks and shoulder joint function was measured by CSA(Constant Shoulder Assessment scale). Results: 1. There was a statistical significance of measured by shoulder pain degree in both group but, the result of a ESWT application group shows more significance than that of a control treatment group. 2. There was a statistical significance of measured by CSA in both group but, the result of a ESWT application group shows more significance than that of a control treatment group. Conclusion: We think that treatment with General physical therapy and ESWT together for the patients with frozen shoulder is more effective and more safe method to shoulder joint function improvement and decrease of pain.

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Clinicopathologic and Diagnostic Significance of p53 Protein Expression in Papillary Thyroid Carcinoma

  • Shin, Mi Kyung;Kim, Jeong Won
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.5
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    • pp.2341-2344
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    • 2014
  • Background: p53 protein expression has been detected immunohistochemically in papillary thyroid carcinoma(PTC). We investigated the relations between its expression and clinicopathologic features and its significance as a diagnostic marker. Materials and Methods: We compared and evaluated 93 patients in whom thyroidectomy with lymph node dissection had been performed to treat PTC for clinicopathologic significance and 102 patients with 23 papillary thyroid overt carcinomas (POC), 57 papillary thyroid microcarcinomas(PMC), 5 follicular adenomas (FA), 5 Hashimoto's thyroiditis (HT) and 12 nodular hyperplasias (NH) for significance as a diagnostic marker. Expression of p53 protein was evaluated immunohistochemically in sections of paraffinembedded tissue. Results: Statistical analysis showed significantly different expression of p53 in PTC versus other benign thyroid lesions (BTL).The diagnostic sensitivity and specificity were 85.0% and 72.7%, respectively. Overexpression of p53 protein was observed in 44 of the 93 PTC cases (47.3%), but no significant correlation between p53 protein overexpression and clinicopathologic features (age, size, multiplicity, lymph node metastasis, extrathyroidal extension and vascular invasion) was noted. Conclusions: p53 is valuable to distinguish PTC from other BTL, but there is no correlation between p53 protein overexpression and clinicopathologic features.

Empirical Bayesian Multiple Comparisons with the Best

  • Kim, Woo-Chul;Hwang, Hyung-Tae
    • Journal of the Korean Statistical Society
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    • v.20 no.2
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    • pp.108-117
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    • 1991
  • A parametric empirical Bayes procedure is proposed and studied to compare treatments simultaneously with the best. Minimum Bayes risk lower bounds are derived for an additive loss function, and their relationship with Bayesian simultaneous confidence lower bounds is given. For the proposed empirical Bayes procedure, the nominal confidence level both in Bayesian sense and in frequentist's sense is shown to be controlled asymptotically. For practical implementation, a measure of significance similar to f-value is suggested with an illustrative example.

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Dependent F Ratios Sharing a Common Cenominator in ANOVA Table

  • Kang, Phillee
    • Journal of the Korean Statistical Society
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    • v.24 no.1
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    • pp.111-125
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    • 1995
  • Let $F_1$ and $F_2$ be two F ratios with independent numerators and a common denominator. They are known to be positively dependent. The probabilities of simultaneous rejection and conditional rejection are numerically computed for both null and nonnull cases. The probabilities are presented in tables and graphics to show the influence of the seven parameters, the degrees of freedom of the numerators and the denominator, the non-centralities of the numerators, and the two levels of significance of the tests. The values of the correlation coefficient between $F_1$ and $F_2$ are also presented. Finally, a conjecture on the dependence order of the family of distributions of $(F_1, F_2)$ is given.

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Statistical notes for clinical researchers: effect size

  • Kim, Hae-Young
    • Restorative Dentistry and Endodontics
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    • v.40 no.4
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    • pp.328-331
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    • 2015
  • Though p values give information on statistical significance, they are confounded with the sample size. Effect size can make up the weak point, by providing information on the actual effect which is independent of the sample size. Therefore, reporting the effect size as well as the p value is recommended.