• Title/Summary/Keyword: statistical evidence

Search Result 561, Processing Time 0.028 seconds

An Introduction to Data Analysis (자료 분석의 기초)

  • Pak, Son-Il;Lee, Young-Won
    • Journal of Veterinary Clinics
    • /
    • v.26 no.3
    • /
    • pp.189-199
    • /
    • 2009
  • With the growing importance of evidence-based medicine, clinical or biomedical research relies critically on the validity and reliability of data, and the subsequent statistical inferences for medical decision-making may lead to valid conclusion. Despite widespread use of analytical techniques in papers published in the Journal of Veterinary Clinics statistical errors particularly in design of experiments, research methodology or data analysis methods are commonly encountered. These flaws often leading to misinterpretation of the data, thereby, subjected to inappropriate conclusions. This article is the first in a series of nontechnical introduction designed not to systemic review of medical statistics but intended to provide the journal readers with an understanding of common statistical concepts, including data scale, selection of appropriate statistical methods, descriptive statistics, data transformation, confidence interval, the principles of hypothesis testing, sampling distribution, and interpretation of results.

Economic Evaluation of Prostate Cancer Screening Test as a National Cancer Screening Program in South Korea

  • Shin, Sangjin;Kim, Youn Hee;Hwang, Jin Sub;Lee, Yoon Jae;Lee, Sang Moo;Ahn, Jeonghoon
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.8
    • /
    • pp.3383-3389
    • /
    • 2014
  • Background: Prostate cancer is rapidly increasing in Korea and professional societies have requested adding prostate specific antigen (PSA) testing to the National Cancer Screening Program (NCSP), but this started a controversy in Korea and neutral evidence on this issue is required more than ever. The purpose of this study was to provide economic evidence to the decision makers of the NCSP. Materials and Methods: A cost-utility analysis was performed on the adoption of PSA screening program among men aged 50-74-years in Korea from the healthcare system perspective. Several data sources were used for the cost-utility analysis, including general health screening data, the Korea Central Cancer Registry, national insurance claims data, and cause of mortality from the National Statistical Office. To solicit the utility index of prostate cancer, a face-to-face interview for typical men aged 40 to 69 was conducted using a Time-Trade Off method. Results: As a result, the increase of effectiveness was estimated to be very low, when adopting PSA screening, and the incremental cost effectiveness ratio (ICER) was analyzed as about 94 million KRW. Sensitivity analyses were performed on the incidence rate, screening rate, cancer stage distribution, utility index, and treatment costs but the results were consistent with the base analysis. Conclusions: Under Korean circumstances with a relatively low incidence rate of prostate cancer, PSA screening is not cost-effective. Therefore, we conclude that adopting national prostate cancer screening would not be beneficial until further evidence is provided in the future.

Adaptation of Evidence-based Surgical Wound Care Algorithm

  • Han, Jung-Yeon;ChoiKwon, Smi
    • Journal of Korean Academy of Nursing
    • /
    • v.41 no.6
    • /
    • pp.768-779
    • /
    • 2011
  • Purpose: This study was designed to adapt a surgical wound care algorithm that is used to provide evidence-based surgical wound care in a critical care unit. Methods: This study used, the 'ADAPTE process', an international clinical practice guideline development method. The -'Bonnie Sue wound care algorithm' - was used as a draft for the new algorithm. A content validity index (CVI) targeting 135 critical care nurses was conducted. A 5-point Likert scale was applied to the CVI test using a statistical criterion of .75. Results: A surgical wound care algorithm comprised 9 components: wound assessment, infection control, necrotic tissue management, wound classification by exudates and depths, dressing selection, consideration of systemic factors, wound expected outcome, reevaluate non-healing wounds, and special treatment for non-healing wounds. All of the CVI tests were ${\leq}$.75. Compared to existing wound care guidelines, the new wound care algorithm provides precise wound assessment, reliabilities of wound care, expands applicability of wound care to critically ill patients, and provides evidence and strength of recommendations. Conclusion: The new surgical wound care algorithm will contribute to the advancement of evidence-based nursing care, and its use is expected as a nursing intervention in critical care.

TESTING FOR SMOOTH TRANSITION NONLINEARITY IN PARTIALLY NONSTATIONARY VECTOR AUTOREGRESSIONS

  • Seo, Byeong-Seon
    • Journal of the Korean Statistical Society
    • /
    • v.36 no.2
    • /
    • pp.257-274
    • /
    • 2007
  • This paper considers the tests for the presence of smooth transition non-linearity in the partially nonstationary vector autoregressive model. The transition parameters cannot be identified under the null hypothesis of linearity, and therefore this paper develops the tests for smooth transition nonlinearity, the associated asymptotic theory and the bootstrap inference. The Monte Carlo simulation evidence shows that the bootstrap inference generates moderate size and power performances.

Long Memory Characteristics in the Korean Stock Market Volatility

  • Cho, Sinsup;Choe, Hyuk;Park, Joon Y
    • Communications for Statistical Applications and Methods
    • /
    • v.9 no.3
    • /
    • pp.577-594
    • /
    • 2002
  • For the estimation and test of long memory feature in volatilities of stock indices and individual companies semiparametric approach, Geweke and Porter-Hudak (1983), is employed. Empirical study supports the strong evidence of volatility persistence in Korean stock market. Most of indices and individual companies have the feature of long term dependence of volatility. Hence the short memory models are unable to explain the volatilities in Korean stock market.

A Nonparametric Bootstrap Test and Estimation for Change

  • Kim, Jae-Hee
    • Communications for Statistical Applications and Methods
    • /
    • v.14 no.2
    • /
    • pp.443-457
    • /
    • 2007
  • This paper deals with the problem of testing the existence of change in mean and estimating the change-point using nonparametric bootstrap technique. A test statistic using Gombay and Horvath (1990)'s functional form is applied to derive a test statistic and nonparametric change-point estimator with bootstrapping idea. Achieved significance level of the test is calculated for the proposed test to show the evidence against the null hypothesis. MSE and percentiles of the bootstrap change-point estimators are given to show the distribution of the proposed estimator in simulation.

Fractional Integration in the Context of Periodicity: A Monte Carlo Experiment and an Empirical Study

  • Gil-Alana Luis A.
    • Communications for Statistical Applications and Methods
    • /
    • v.13 no.3
    • /
    • pp.587-605
    • /
    • 2006
  • Recent results in applied statistics have shown that the presence of periodicities in time series may influence the estimation and testing of the fractional differencing parameter. In this article, we provide further evidence on the issue by using several procedures of fractional integration. The results show that in the presence of periodicities, the order of integration can be erroneously detected. An empirical application in the context of seasonal data is also carried out at the end of the article.

Adjusting Practical Aims in Optimal Extended Double Sampling Plans

  • Ko, Seoung-gon
    • Communications for Statistical Applications and Methods
    • /
    • v.6 no.1
    • /
    • pp.143-150
    • /
    • 1999
  • Ko(1998) proposed a procedure to enhance the efficiency of double sampling plans by allowing second-stage sample size and critical region to depend on first-stage evidence using constraint optimization approaches. In this study further developments of such plans by incorporating several practically possible researcher's aims into the optimization are considered. Comparisons are made with the optimal ordinary double sampling plan and also among them It is observed that it is to some extent possible to match the details of the optimization to certain qualitative methodological aims.

  • PDF

BAYESIAN INFERENCE FOR MTAR MODEL WITH INCOMPLETE DATA

  • Park, Soo-Jung;Oh, Man-Suk;Shin, Dong-Wan
    • Proceedings of the Korean Statistical Society Conference
    • /
    • 2003.05a
    • /
    • pp.183-189
    • /
    • 2003
  • A momentum threshold autoregressive (MTAR) model, a nonlinear autoregressive model, is analyzed in a Bayesian framework. Parameter estimation in the presence of missing data is done by using Markov chain Monte Carlo methods. We also propose simple Bayesian test procedures for asymmetry and unit roots. The proposed method is applied to a set of Korea unemployment rate data and reveals evidence for asymmetry and a unit root.

  • PDF

SOME GENERALIZED GAMMA DISTRIBUTION

  • Nadarajah Saralees;Gupta Arjun K.
    • Journal of the Korean Statistical Society
    • /
    • v.36 no.1
    • /
    • pp.93-109
    • /
    • 2007
  • Gamma distributions are some of the most popular models for hydrological processes. In this paper, a very flexible family which contains the gamma distribution as a particular case is introduced. Evidence of flexibility is shown by examining the shape of its pdf and the associated hazard rate function. A comprehensive treatment of the mathematical properties is provided by deriving expressions for the nth moment, moment generating function, characteristic function, Renyi entropy and the asymptotic distribution of the extreme order statistics. Estimation and simulation issues are also considered. Finally, a detailed application to drought data from the State of Nebraska is illustrated.