• Biomolecules & Therapeutics
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• 제14권3호
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• pp.152-159
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• 2006

Electro-magnetic fields and static magnetic fields generated from diverse home/environmental sources have been reported that these could make harmful effects on the human health such as suppression of immunity and tumorigenesis. However, the mechanisms for the biologic effects of electro-magnetic fields or static magnetic fields are still remained unclear. In this study, we examined the in vitro effects of static magnetic fields (SMF) on murine peritoneal macrophages. The cells were exposed in vitro to SMF of $150{\sim}250$ or $350{\sim}450$ G in 5% $CO_2$-incubator. The phagocytic activity of murine peritoneal macrophages was inhibited under exposure to SMF. In order to provide a more complete picture of molecular mechanism for the biological effect of SMF, we compared the levels of total proteins from macrophages with or without exposure to SMF using quantitative proteomic analysis. Proteins which were differentially expressed in macrophages exposed to SMF compared with non-exposed macrophages, were identified. Among them, the levels of trypsinogen 16, lactose-binding lectin Mac-2, galactoside-binding lectin, actin-like (Put. ${\beta}-actin$, vimentin) and electron transferring flavoprotein beta polypeptide were enhanced under exposure to SMF. These results suggest that SMF can affect the phagocytic activity of macrophages via diverse mechanisms.

• 대한치과교정학회지
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• 제27권6호
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• pp.929-941
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• 1997

가장 바람직한 교정력은 환자에게 불편감을 주지 않고 치조골 상실과 치근흡수와 같은 조직의 손상없이 가장 빨리 치아를 이동시키는 힘이다. 최적의 교정력을 얻기 위하여 그 동안 많은 방법들이 시도되어 왔으며 최근에는 자석의 사용이 고려되고 있다. 본 연구는 Sm-Co 자석의 정자기장이 효소와 세포 활성에 미치는 영향을 알아보기 위하여 시행되었다. 적혈구 침강속도가 측정되었으며, 철이온과 관련된 효소 (Catalase, NO synthase)와 철이온과 무관한 효소 (Lactic dehydrogenase)의 활성과 세포내 합성은 Spectrophotometer를 이용하여 측정되었으며, 조골세포 $MC_{3}T_3-E_1$의 성장과 증식은 Crystal violet 염색법과 ${^3}H$-thymidine incorporation에 의한 DNA합성능을 측정하였다. 실험군의 적혈구는 표면자기장이 1,400 G (gauss)인 자석에, 효소와 조골세포는 7,000 G의 정자기장에 노출시키고, 정자기장에 노출시키지 않은 경우와 비교하여 다음과 같은 결과를 얻었다. 1. 적혈구 침강속도는 정자기장의 영향을 받지 않았다. 2. Catalase와 Lactic dehydrogenase의 활성은 정자기장의 영향을 받지 않았다. 3. NO synthase와 Lactic dehydrogenase의 세포내 합성은 정자기장의 영향을 받지 않았다. 4. 세포배양된 조골세포 $MC_{3}T_3-E_1$의 성장과 증식은 정자기장의 영향을 받지 않았다. 이상의 결과로 보아 정자기장은 효소와 세포 활성에 대한 영향이 없는 것으로 사료되었다.

• 한국안전학회지
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• 제22권6호
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• pp.87-90
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• 2007

최근 의료분야에서 인체의 생리학적 조직에 정자계가 영향을 미치는 것으로 밝혀짐에 따라 정자계를 사용하는 의료장비의 중요성이 대두되고 있다. 본 연구의 목적은 자속의 영향에 의한 혈중 산소 포화 농도의 변화를 평가하는 것이다. 본 연구의 결과는 검지 손가락에 정자계 쌍극자가 맞추어졌을 때 혈중 산소포화 농도가 증가한다는 것을 보여준다.

• 한국전자파학회:학술대회논문집
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• 한국전자파학회 1999년도 제3회 전자장의 생체영향에 관한 워크숍
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• pp.117-129
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• 1999

Acute effects of locally applied of static magnetic field (SMF) and extremely low frequency electromagnetic field(ELF-EMF) to the cutaneous tissue within a rabbit ear chamber (REC)were evaluated under conscious conditions. Rabbits with the REC were subjected to intravital microscopical investigation by use of microphotoelectric plethysmography(MPPG). There was no dose-response relationship between the extent of vasomotion changes and frequencies(0,20,50, 100Hz)or power levels (1, 5, 10, 25, 50, 100, 200 mT). Under low vascular tone the both fields induce vasodilatation. The effects of SMF (1 mT) on the cutaneous microcirculatory system induced the vasodilatation with enhanced vasomotion under nor-adrenaline-induced high vascular tone as well as the vasoconstriction with reduced vasomotion under acetylcholine-induced low vascular tone. This suggests that the SMF can modulate vascular tone due to the modification of vasomotion biphasically in the cutaneous tissue.

• Journal of Radiation Protection and Research
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• 제20권3호
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• pp.143-154
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• 1995

최근에 정자기장을 사용하는 새로운 기술이 개발되어 인체가 정자기장에 노출될 가능성이 커지게 되어 건강에 영향을 줄 우려도 증가되었다. 여러 나라에서 정부를 비롯한 권위 있는 기관들이 주로 자기공명 영상법(MRI)이나 고에너지물리학에서의 입자가속기와 같은 특수 용도를 위해 노출한도를 제시해 왔다. 산업적인 면과 의학에서의 정자기장의 응용이 앞으로 더 많아져서 직업적이거나 일반공중이거나 간에 노출 가능성이 증가되고, 또 정자기장(static magnetic field)에 영향을 받는 강자성(强磁性) 이식조직 이나 전자장치를 부착한 사람들의 수도 증가하고 있으므로 국제적인 노출한도에 대한 지침이 필요하게 되었다. 본고에서는 비 이온화방사선(NIR)에 대한 국제방사선방어학회/비이온방사선방어위원회(IRPA/ICNIRP)의 제반지침을 검토하기 위하여 이 IRPA/ICNIRP(이전의 INIRC의 것도 포함)의 기본지침 중 정자기장에 대한 노출한도에 관한 지침을 택하여 논하였다.

• 대한전기학회논문지
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• 제38권12호
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• pp.1033-1047
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• 1989

A finite element method for the analysis of magnetic fields with hysteresis characteristics is proposed. The method employs Preisach model to describe hysteresis of magnetic material, so that even multi-branch or minor-loop characteristics can be taken into account. The problem can be considered as the analysis of a nonlinear equation where magnetization depends not only on the present value of the magnetic field but also on the past values, and the problem can be solved by the iteration method. Measurements were carried out on soft ferrite EI core for the comparison with computer solution, and good agreements were obtained. is investigated. A theoretical approach to gait study is proposed in which the static stability margins for periodic gaits are expressed in terms of the kinematic gait formula. The effects fo the stride length on static stability are analyzed and the relations between static stability and initial body configurations are examined. It is shown that the moving velocity can be increased to some extent without affecting stability margins for a given initial body configuration. Computer simulations are performed to verify the analysis.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.113-113
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• 2003

A number of studies have demonstrated recently nonthermal interactions of extremely low frequency electromagnetic fields with cellular systems, such as the cells of the immune system. Particular concern came from epidemiological findings, which correlated environmental exposure of human body to weak electromagnetic fields with an elevated risk for developing certain type of leukemias and cancers. Several home/environmental sources generating extremely low frequency electromagnetic fields, such as 50 - 60 Hz high-voltage transmission lines, video display terminals, electric blankets, clinical nuclear magnetic resonance imaging procedures, etc., may interact with the human body. In this study we examined the effects of static magnetic fields (SMF) on the phagocytosis of the murine peritoneal macrophages (C57BL/6). The cells were exposed in vitro for 24 h at 37$^{\circ}C$ to 400 G SMF. The phagocytic activity of peritoneal macrophages was determined with a luminometer. Exposure to the SMF decreased phagocytic activity of murine peritoneal macrophages. In order to provide a more exact mechanism of the phenomenon, we analyzed peritoneal macrophages for alteration in their proteomes. The expression levels of these 5 proteins were increased in the SMF. In total 5 proteins which were differentially expressed in the SMF compared with control group were identified. The expression levels of these 5 proteins were increased in the SMF.

• Bulletin of the Korean Chemical Society
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• 제34권3호
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• pp.823-826
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• 2013

A low-${\varepsilon}$ solid-state NMR(Nuclear Magnetic Resonance) probe was developed for the spectroscopic analysis of two-dimensional $^{15}N-^1H$ heteronuclear dipolar coupling in dilute membrane proteins oriented in hydrated and dielectrically lossy lipid environments. The system employed a 800 MHz narrow-bore magnet. A solenoid coil strip shield was used to reduce deleterious RF sample heating by minimizing the conservative electric fields generated by the double-tuned resonator at high magnetic fields. The probe's design, construction, and performance in solid-state NMR experiments at high magnetic fields are described here. Such high-resolution solid-state NMR spectroscopic analysis of static oriented samples in hydrated phospholipid bilayers or bicelles could aid the structural analysis of dilute biological membrane proteins.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2002년도 Proceedings of International Symposium on Remote Sensing
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• pp.242-242
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• 2002

The Earth's magnetic field acquired from KOMPSAT-1's TAM (Three-Axis Magnetometer) between June 19th and 21st 2000 was analyzed. The TAM, one of the KOMPSAT-1's Attitude and Orbit Control Subsystems, plays an important role in determining and controlling the satellite's attitude. This also can provide new insight on the Earth's magnetic field. By transforming the satellite coordinate from ECI to ECEF, spherical coordinate of total magnetic field was achieved. These data were grouped into dusk (ascending) and dawn (descending) data sets, based on their local magnetic times. This partitioning is essential for performing 1-D WCA (Wavenumber Correlation Analysis). Also, this enhances the perception of external fields in the Kompsat-1's TAM magnetic maps that were compiled according to different local. The dusk and dawn data are processed independently and then merged to produce a total field magnetic anomaly map. To extract static and dynamic components, the 1-D and 2-D WCAs were applied to the sub-parallel neighboring tracks and dawn-dusk data sets. The static components were compared with the IGRF, the global spherical harmonic magnetic field model. The static and dynamic components were analyzed in terms of corefield, external, and crustal signals based on their origins.

• Steel and Composite Structures
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• 제26권4호
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• pp.513-531
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• 2018

In this article, static, buckling and free vibration analyses of a sinusoidal micro composite beam reinforced by single-walled carbon nanotubes (SWCNTs) with considering temperature-dependent material properties embedded in an elastic medium in the presence of magnetic field under transverse uniform load are presented. This system is used at micro or sub micro scales to enhance the stiffness of micro composite structures such as bar, beam, plate and shell. In the present work, the size dependent effects based on surface stress effect and modified strain gradient theory (MSGT) are considered. The generalized rule of mixture is employed to predict temperature-dependent mechanical and thermal properties of micro composite beam. Then, the governing equations of motions are derived using Hamilton's principle and energy method. Numerical results are presented to investigate the influences of material length scale parameters, elastic foundation, composite fiber angle, magnetic intensity, temperature changes and carbon nanotubes volume fraction on the bending, buckling and free vibration behaviors of micro composite beam. There is a good agreement between the obtained results by this research and the literature results. The obtained results of this study demonstrate that the magnetic intensity, temperature changes, and two parameters elastic foundations have important effects on micro composite stiffness, while the magnetic field has greater effects on the bending, buckling and free vibration responses of micro composite beams. Moreover, it is shown that the effects of surface layers are important, and observed that the changes of carbon nanotubes volume fraction, beam length-to-thickness ratio and material length scale parameter have noticeable effects on the maximum deflection, critical buckling load and natural frequencies of micro composite beams.