• International Journal of Naval Architecture and Ocean Engineering
• /
• v.6 no.2
• /
• pp.431-441
• /
• 2014

The effects of hull-girder vibration on the fatigue strength of a Post-Panamax container ship are discussed in the present paper. Firstly, the short-term sea states are categorized according to the occurrence probability of each sea state. Time histories of hull-girder stress in short-term sea states are calculated by means of a nonlinear simulation code of ship response assuming that the hull-girder is rigid and flexible. Then, the calculated stress peaks are processed by the rainflow counting method, where two different counting procedures are used based on the considerations of crack propagation behaviors. Finally, the fatigue damage in life time of the ship in each categorized short-term sea state is estimated by means of Miner's rule. Based on the calculated results, the effects of hull-girder vibrations on the fatigue damage are clarified by disaggregated damage from short-term sea state.

• Journal of Korean Tunnelling and Underground Space Association
• /
• v.4 no.1
• /
• pp.57-70
• /
• 2002

Since early in the 90's, the need for construction of underground rock structures such as long and large section traffic tunnel, energy storage cavern, industrial facility, etc. has been largely increased because the Korean territory is not wide and about 65 % of the land consists of mountainous region. The initial rock stress measurement has been widely conducted to provide the quantitative information on the stress state of engineering site at the design stage of underground rock structures. Among the diverse methods developed for measuring rock stress, hydraulic fracturing test is most popularly used because it is applicable at pre-construction stage and has no limit in testing depth. In this paper, the characteristics of initial rock stress state in mountainous region were studied on the basis of the in-situ hydraulic fracturing stress measurement results from the 60 test boreholes in various parts of Korea.

• KCI Concrete Journal
• /
• v.11 no.3
• /
• pp.53-64
• /
• 1999

A theory is proposed to predict the response of the load-deformation relationship of the reinforced concrete structures under the service state after cracking. The crack direction and concrete strains through the loading history before failure can be estimated by this theory based on the rotating crack model, which considers equilibrium, compatibility conditions, and average stress-strain relationship. The proposed crack direction and deformation show good agreement with test results under service state. The behavior of a variety of concrete structures, such as shear walls, deep beams and the web of box girders, can be predicted by this proposed theory under service state.

• Journal of the Korean Society of Safety
• /
• v.8 no.4
• /
• pp.27-40
• /
• 1993

High temperature tensile tests, steady state creep tests, Internal stress tests and creep rupture tests using A17075 alloy( $T_{6}$ ) were performed over the temperature range of 9$0^{\circ}C$~50$0^{\circ}C$ (0.4 $T_{m}$ ~0.85 $T_{m}$ ) and stress range of 0.64~17.2(kgf/$\textrm{mm}^2$). The main results obtained in this paper were as follows. (1) The activation energies for yielding at the temperature of 0.4 $T_{m}$ ~0.75 $T_{m}$ were calculated to be 25.7~36.5kcal/mol, which were nearly equal to the activation energies for creep. (2) At around the temperature of 9$0^{\circ}C$~12$0^{\circ}C$ and under the stress level of 10~17.2(kgf/$\textrm{mm}^2$), and at around the temperature of 200~41$0^{\circ}C$ and under the stress level of 1.53~9.55(kgf/$\textrm{mm}^2$) and again at around the temperature of 470~50$0^{\circ}C$ and under the stress level of 0.62~l.02(kgf/$\textrm{mm}^2$), the applied stress dependence of steady state creep rate $n_{measu}$ measured were, respectively, 3.15, 6.62 and 1.1, which were in good agreement the calculated stress dependence $n_{ealeu}$ obtained by the difference of the applied stress dependence of the Internal stress and the ratio of the internal stress to the applied stress. (3) At the temperature range of 0.4~0.43 $T_{m}$ , and at the temperature range of 0.52~0.75 $T_{m}$ and again at the temperature range of 0.82~0.85 $T_{m}$ , the activation energies $Q_{measu}$ obtained by steady state creep rate, respective, 26. 16, 34.9, 36.2 and 36.1kcal/mol, which were in good agreement with those obtained with the activation energies under constant effective stress and the temperature dependence of Internal stress. (4) At the temperature range of the 0.52~0.73 $T_{m}$ and under the stress level of 1.53~9.55(kgf/$\textrm{mm}^2$), the stress dependence of rupture life(n’) measured was 6.3~6.6, which was in good agreement with the stress dependence of steady state creep rate(n). And at the same condition the activation energy for rupture( $Q_{f}$ ) measured was 32.0~36.9kca1/mol, which was also in good agreement with the activation energy obtained by steady state creep rate ( $Q_{c}$ ). (5) The rupture life( $t_{f}$ ) might be represented by athermal process attributed to the difference of the applied stress dependence of the internal stress and the ratio of the internal stress to the applied stress, and the thermal activated process attributied to the temperature dependence of the internal stress as $t_{f}$ = A'$\sigma$$_{a}$ ｛n(1-d $\sigma$$_{i}$ /d $\sigma$$_{a}$ )/(1-$\sigma$$_{i}$ / $\sigma$$_{a}$ )｝.exp[｛ $Q_{c}$ $^{*}$-( $n_{o}$ R $T^2$/ $E_{(T)}$) (d $E_{(T)}$/dT) - ( $n_{0}$ R $T^2$/ $\sigma$$_{a}$ - $\sigma$$_{i}$ ) (d $\sigma$$_{i}$ /dT)｝/RT]. (6) The relationship betwween Larson-Miller rupture parameter and logarithmic stress was linearly decreased, so creep rupture life of Al 7075 alloy seemed to be predicted exactly with Larson-Miller parameter.meter.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.13
• /
• pp.5201-5205
• /
• 2014

Emodin, a natural anthraquinone isolated from the traditional Chinese medicine Radix rhizoma Rhei, can induce apoptosis in many kinds of cancer cells. This study demonstrated that emodin induces apoptosis in human colon cancer HCT116 cells by provoking oxidative stress, which subsequently triggers a p53-mitochondrial apoptotic pathway. Emodin induced mitochondrial transmembrane potential loss, increase in Bax and decrease in Bcl-2 expression and mitochondrial translocation and release of cytochrome c to cytosol in HCT116 cells. In response to emodin-treatment, ROS increased rapidly, and subsequently p53 was overexpressed. Pretreatment with the antioxidant NAC diminished apoptosis and p53 overexpression induced by emodin. Transfecting p53 siRNA also attenuated apoptosis induced by emodin, Bax expression and mitochondrial translocation being reduced compared to treatment with emodin alone. Taken together, these results indicate that ROS is a trigger of emodin-induced apoptosis in HCT116 cells, and p53 expression increases under oxidative stress, leading to Bax-mediated mitochondrial apoptosis.

• Journal of Microbiology and Biotechnology
• /
• v.23 no.12
• /
• pp.1737-1746
• /
• 2013

IbMYB1, a transcription factor (TF) for R2R3-type MYB TFs, is a key regulator of anthocyanin biosynthesis during storage of sweet potatoes. Anthocyanins provide important antioxidants of nutritional value to humans, and also protect plants from oxidative stress. This study aimed to increase transgenic potatoes' (Solanum tuberosum cv. LongShu No.3) tolerance to environmental stress and enhance their nutritional value. Transgenic potato plants expressing IbMYB1 genes under the control of an oxidative stress-inducible peroxidase (SWPA2) promoter (referred to as SM plants) were successfully generated through Agrobacterium-mediated transformation. Two representative transgenic SM5 and SM12 lines were evaluated for enhanced tolerance to salinity, UV-B rays, and drought conditions. Following treatment of 100 mM NaCl, seedlings of SM5 and SM12 lines showed less root damage and more shoot growth than control lines expressing only an empty vector. Transgenic potato plants in pots treated with 400 mM NaCl showed high amounts of secondary metabolites, including phenols, anthocyanins, and flavonoids, compared with control plants. After treatment of 400 mM NaCl, transgenic potato plants also showed high DDPH radical scavenging activity and high PS II photochemical efficiency compared with the control line. Furthermore, following treatment of NaCl, UV-B, and drought stress, the expression levels of IbMYB1 and several structural genes in the flavonoid biosynthesis such as CHS, DFR, and ANS in transgenic plants were found to be correlated with plant phenotype. The results suggest that enhanced IbMYB1 expression affects secondary metabolism, which leads to improved tolerance ability in transgenic potatoes.

• Journal of the Earthquake Engineering Society of Korea
• /
• v.12 no.1
• /
• pp.29-42
• /
• 2008

The objective of this study is to investigate the effects of rigid end platens on effective stresses in soil mass during consolidation. The friction between the teeth of top cap/base pedestal and the specimen during consolidation decreases the radial and tangential effective stresses in RC specimens. However, it is unpractical to measure the effective stresses in the soil specimen. Two approaches were used to evaluate the state of stress in RC specimens during consolidation. First, careful measurements were made of small strain shear modulus, $G_{max}$ in specimens with carefully controlled void ratios and stress histories, to infer the state of stress. And second, a finite element analysis was performed to analytically evaluate the effect of various soil parameters on the state of stress in RC specimens during consolidation. By combining these experimental and analytical results, an example was performed to predict the average state of stress in RC specimens during consolidation.

• Child Health Nursing Research
• /
• v.12 no.3
• /
• pp.417-425
• /
• 2006

Purpose: This study was done to investigate stress, coping and social support of mothers of children with seizure disorders, and to identify the relationship between these variables. Method: The participants were 105 mothers of children with seizure disorders. Data were collected through self-report questionnaires which were constructed to include stress, coping and social support. The data were analyzed using the SAS program. Result: Stress of mothers was significantly different according to number of times the child had been hospitalized and the mothers perception of the state of the child's health. Coping by mothers was significantly different according to religion, general health state and if mother knew the child's diagnosis. Social support for mothers was significantly different according to education level, monthly medical expenses and number of times the child had been hospitalized. Social support for mothers was correlated with stress and coping. Conclusion: The above findings indicate that coping in mothers of children with seizure disorder is related to social support. Therefore nursing interventions to reduce stress and improve coping should be provided for mothers of children with seizure disorder.

• Restorative Dentistry and Endodontics
• /
• v.43 no.4
• /
• pp.48.1-48.13
• /
• 2018

Objectives: To analyze the influence of thickness and incisal extension of indirect veneers on the stress and strain generated in maxillary canine teeth. Materials and Methods: A 3-dimensional maxillary canine model was validated with an in vitro strain gauge and exported to computer-assisted engineering software. Materials were considered homogeneous, isotropic, and elastic. Each canine tooth was then subjected to a 0.3 and 0.8 mm reduction on the facial surface, in preparations with and without incisal covering, and restored with a lithium disilicate veneer. A 50 N load was applied at $45^{\circ}$ to the long axis of the tooth, on the incisal third of the palatal surface of the crown. Results: The results showed a mean of $218.16{\mu}strain$ of stress in the in vitro experiment, and $210.63{\mu}strain$ in finite element analysis (FEA). The stress concentration on prepared teeth was higher at the palatal root surface, with a mean value of 11.02 MPa and varying less than 3% between the preparation designs. The veneers concentrated higher stresses at the incisal third of the facial surface, with a mean of 3.88 MPa and a 40% increase in less-thick veneers. The incisal cover generated a new stress concentration area, with values over 48.18 MPa. Conclusions: The mathematical model for a maxillary canine tooth was validated using FEA. The thickness (0.3 or 0.8 mm) and the incisal covering showed no difference for the tooth structure. However, the incisal covering was harmful for the veneer, of which the greatest thickness was beneficial.

• Geomechanics and Engineering
• /
• v.9 no.5
• /
• pp.645-667
• /
• 2015

Single treatment and staged treatments in vertical wells are widely applied in sandstone and mudstone thin interbedded (SMTI) reservoir to stimulate the reservoir. The keys and difficulties of stimulating this category of formations are to avoid hydraulic fracture propagating through the interface between shale and sand as well as control the fracture height. In this paper, the cohesive zone method was utilized to build the 3-dimensional fracture dynamic propagation model in shale and sand interbedded formation based on the cohesive damage element. Staged treatments and single treatment were simulated by single fracture propagation model and double fractures propagation model respectively. Study on the changes of fracture vicinity stress field during propagation is to compare and analyze the parameters which influence the interfacial induced stresses between two different fracturing methods. As a result, we can prejudge how difficult it is that the fracture propagates along its height direction. The induced stress increases as the pumping rate increasing and it changes as a parabolic function of the fluid viscosity. The optimized pump rate is $4.8m^3/min$ and fluid viscosity is $0.1Pa{\cdot}s$ to avoid the over extending of hydraulic fracture in height direction. The simulation outcomes were applied in the field to optimize the treatment parameters and the staged treatments was suggested to get a better production than single treatment.