• 대한한의학원전학회지
• /
• 제24권6호
• /
• pp.29-38
• /
• 2011

The concept of Blood Stasis had been cognized merely as a sign in disorder of blood circulation since "Huangjenaegyeong(黃帝內經)" until "Sanhanron(傷寒論)" and "Geumgweyoryak(金匱要略)" started to describe, explain and apply independent symptom of blood stasis to practice. In this article, establishing the estimate feature of symptom of blood stasis in "Geumgweyoryak(金匱要略)" is the main subject, in sequence the pathological mechanism and targets of prescriptions suggested in "Geumgweyoryak(金匱要略)" are analyzed and restructured. In conclusion, the symptom of blood stasis in "Geumgweyoryak(金匱要略)" is caused not only from disorder of blood circulation but also from metal depression, therefore there are always appearances of excessive and deficient status simultaneously, in the process of symptom. The research on concept of blood stasis from the literatures in early ages will be the basis of future studies about disease of circulation in Korean Traditional Medicine.

• 대한한방부인과학회지
• /
• 제23권4호
• /
• pp.130-145
• /
• 2010

Purpose: The purpose of this study is to know stress and blood stasis pattern for the patients who had hysterectomy related with uterine myoma, adenomyosis, endometriosis. Methods: We got questionnaires from 55 patients among 243 patients who had hysterectomy related with uterine myoma, adenomyosis, endometriosis in the department of obstetrics and gynecology, OO medical center from April 11th 2010 to October 14th 2010, and analyzed them. We conducted correlation analysis between age, pain(VAS), duration of pain and blood stasis score, and between duration of pain, blood stasis score and the sum of Stress Response Index. We compared the sum of Stress Response Index, blood stasis score, VAS according to the result of pathology. For statistics, we used Pearson's correlation coefficient, Mann-Whitney test, oneway analysis of variances(ANOVA) and SPSS version 17.0 for windows. Results: The correlation between duration of pain and blood stasis score showed statistical significance. The correlation between sum of the Stress Response Index and blood stasis score showed statistical significance. There is no statistically correlation between age, VAS, duration of the pain and blood stasis score. There is no statistically significant difference in sum of Stress Response Index, blood stasis score, VAS according to the result of pathology. Conclusion: The result showed that Stress is related with static blood, and the longer patients suffer from pain, the easier patients' blood to be static. Further study will be needed.

• 한방재활의학과학회지
• /
• 제23권4호
• /
• pp.159-167
• /
• 2013

Objectives In this study, we wanted to find out the characteristics - gender, SLR test, valsalva test, duration, ESR, CRP and night pain - of lumbar disc herniation being classified as blood stasis and phlegm-retained fluid. Methods We surveyed 42 patients suffering from lumbar disc herniation using the diagnosis blood stasis syndrome, water retention syndrome of the comprehensive diagnosis of QI blood water. Blood stasis and phlegm-retained fluid are identical with blood stasis syndrome, water retention syndrome. Then we analyzed the characteristics - gender, SLR test, valsalva test, duration, ESR, CRP and night pain - of the patients suffering from lumbar disc herniation who were diagnosed as blood stasis and phlegm-retained fluid. Results Patients were sorted into two groups: 18 blood stasis patients and 30 phlegm-retained fluid patients. Gender (Woman), acute phase and night pain are related to blood stasis. Acute phase, positive of SLR test is related to phlegm-retained fluid. There was no correlation between blood stasis and SLR test, valsalva test, duration, ESR, CRP. Also no correlation between phlegm-fluid and gender, valsalva test, duration, ESR, CRP and night pain. Conclusions By Considering the characteristics - gender, SLR test, valsalva test, duration, ESR, CRP and night pain - of lumbar disc herniation patients, it can help to analyze the pattern of its symptoms.

• 동의생리병리학회지
• /
• 제26권5호
• /
• pp.778-783
• /
• 2012

We report a rare case of non-traumatic spontaneous intramuscular mass of blood stasis, especially gastrocnemius muscle, associated with alcoholic liver cirrhosis. A 53-year-old man with alcoholic liver cirrhosis was admitted to our hospital for ICH. It was improved by Korean Medicine treatments, however, he was complaint of severe pain in left calf. Ultrasound revealed intramuscular hypoechoic mass at the left gastrocnemius muscle and we diagnose it as mass of blood stasis, which is similarly called 'hematoma' in Western medicine. Herbal extracts, acupuncture and indirect moxibustion reduced it, but the effects could not be compared as there were no reports of these kinds. It seems important to consider intramuscular mass of blood stasis as a complication of alcoholic liver cirrhosis and Ultrasound seems to be very useful in diagnosis and observation of intramuscular mass of blood stasis.

• 대한한방부인과학회지
• /
• 제24권1호
• /
• pp.132-143
• /
• 2011

Objectives: The purpose of this study is to know the correlation of transvaginal sonography findings, CA-125 and blood stasis pattern for 15 adenomyosis patients. Methods: We got questionnaires from 15 patients among 243 patients who had hysterectomy related with adenomyosis in the department of obstetrics and gynecology, OO medical center from April 11th 2010 to November 15th 2010, and analyzed them. We conducted correlation analysis between age, pain(VAS), duration of pain and blood stasis score, and between difference and sum of uterine walls, CA-125 and blood stasis score. For statistics, we used Spearman correlation coefficient and SPSS version 17.0 for windows. Results: The correlation between sum of uterine walls and CA-125 showed statistical significance. The correlation between CA-125 and blood stasis score showed statistical significance. There is no statistically correlation between age, VAS, duration of the pain and blood stasis score. There is no statistically correlation between difference of uterine walls and CA-125, and between difference and sum of uterine walls and blood stasis score. Conclusion: The result showed that sum of uterine walls is related with CA-125. We need a further study to develop blood stasis indicators with a validated questionnaire, and more subjects involved at multiple institutions.

• 대한예방한의학회지
• /
• 제24권2호
• /
• pp.95-102
• /
• 2020

Objectives : The objective of this study was to revise the modified Blood Stasis Questionnaire II. Methods : This revision focused on refining the Korean literature expression of Blood Stasis Questionnaire II consisting of 30-question questionnaire. Seven external experts and five researchers of Korean Institute of Oriental Medicine reviewed the questionnaire and its protocol, while the addition or deletion of questions and changes in scoring method were not dealt with in this revision. Results : Among thirty questions, four questions were corrected to appropriate expressions. In case of eight questions, explanations in Korean or Chinese were added. Thirteen questions in the phrase were changed in sentence form to unify the whole questionnaire. Conclusions : This study introduces the revised version of the modified Blood Stasis Questionnaire II. It is expected that clinical demand of this questionnaire will increase and it will be used vigorously in blood stasis research.

• 대한한의학회지
• /
• 제27권3호
• /
• pp.241-250
• /
• 2006

Backgrounds: Blood stasis is hon as an important pathologic factor for vascular disorder in Oriental medicine. Despite its clinical importance there have been few objective tests for diagnosing blood stasis. Objectives: This study was designed to examine the relationship between blood stasis and arterial stiffness measured by cardio-ankle vascular index (CAVI). Methods: The subjects were 104 ischemic stroke patients with onset after 14 days. Their general characteristics, lipid profiles and uric acid were recorded. The degree of arterial stiffness was assessed by CAVI, and blood stasis was evaluated by diagnostic criteria. The data were analyze4 by chi-square test, student t-test, spearman correlation analysis, and pearson correlation analysis. Then, stepwise multiple logistic regression analysis was applied in order to exclude the interactions among several factors. Results: There were significant differences in right, left and higher CAVI between the blood stasis group and the non blood stasis group (p-value<0.01). Age, systolic blood pressure, triglyceride and CAVI had relationships with blood static scores. In multiple logistic regression analysis, the adjusted odds ratio of blood stasis for arterial stiffness with CAVI above 9 were 7.091 (95% confidence interval, $1.641\sim30.638$). Conclusions: The results demonstrated the relationship between blood stasis and arterial stiffness measured by CAVI. Therefore, we suggest that CAVI should be one of the objective tests for diagnosing blood stasis.

• 대한한방부인과학회지
• /
• 제18권4호
• /
• pp.165-182
• /
• 2005

Purpose : To investigate the stress degree of infertile women and its correlations with Qi-stasis. Methods : 162 women, enrolled for treatment at oriental hospital, completed Infertility Stress Scale, Stress Response Inventory and Qi-stasis questionnaire. Their demographic features and infertility-related factors were recorded. 137 infertile women and 25 normal subjects were analyzed. Results : 1. 43 infertile women(33.86%) among the sample group were diagnosed as Qi-stasis. 2. There were close score correlations among Infertility Stress Scale, Stress Response Inventory, and Qi-stasis(p=.000). 3. Experience of Assisted Reproductive Technology (ART), possibility of spontaneous pregnancy, coitus frequency, whether the spouse is the eldest son or not had the influences on Infertility Stress. Abortion experience had influences on stress response and Qi-stasis. 4. It was revealed that Infertile women(n=137) had significantly higher scores of 'Infertility Stress' and subscales such as 'sexual satisfaction', 'marital satisfaction', 'familial adjustment', 'social adjustment' as well than control group(n=25). Conclusion : The results provide that the stress degree of infertile women had significant correlations with Qi-stasis and show the possibilities of oriental medicine treatment for stresses of infertile women.

• 동의신경정신과학회지
• /
• 제28권2호
• /
• pp.137-143
• /
• 2017

Objectives: Insomnia is a common disease in the general population. The purpose of this paper was to suggest that insomnia subtype of blood stasis can be effectively treated with Danggwisu-san and acupuncture. Methods: This is a clinical case report of a patient with chronic insomnia that was diagnosed with blood stasis subtype. I treated him with Danggwisu-san (Dangguixu-san) two to three times daily and with acupuncture and moxibustion two to three times weekly. Results: After short-term treatment, the patient was gradually recovering from deteriorating chronic insomnia and multiple accompanying symptoms such as severe constipation, spontaneous bleeding and edema, darkened face, depressive moods, etc. Conclusions: Results revealed a possibility that chronic insomnia subtype of blood stasis may be successfully treated with Danggwisu-san and acupuncture and moxibustion.

• 대한약침학회지
• /
• 제17권2호
• /
• pp.41-45
• /
• 2014

Objectives: This study was performed to analyze the single-dose toxicity of neutral natured blood stasis pharmacopuncture extracts. Methods: All experiments were conducted at Biotoxtech, an institution authorized to perform non-clinical studies, under the regulations of Good Laboratory Practice (GLP). Sprague-Dawley rats were chosen for the pilot study. Doses of neutral natured blood stasis pharmacopuncture extracts, 0.1, 0.5 and 1.0 mL, were administered to the experimental group, and the same doses of normal saline solution were administered to the control group. This study was conducted under the approval of the Institutional Animal Ethics Committee. Results: In all 4 groups, no deaths occurred, and the neutral natured blood stasis pharmacopuncture extracts administered by intramuscular (IM) injection was over 1.0 mL/animal. No significant changes in the body weights between the control group and the experimental group were observed. To check for abnormalities in organs and tissues, we used microscopy to examine representative histological sections of each specified organ; the results showed no significant differences in any organs or tissues. Conclusion: The above findings suggest that treatment with neutral natured blood stasis pharmacopuncture extracts is relatively safe. Further studies on this subject should be conducted to yield more concrete evidence.