• Title/Summary/Keyword: standard of diagnosis

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An Aggressive Large Epithelioid Hemangioendothelioma of the Anterior Mediastinum in a Young Woman

  • Dutta, Roman;Pal, Harish;Garg, Garima;Mohanty, Sambit
    • Journal of Chest Surgery
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    • v.51 no.6
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    • pp.419-422
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    • 2018
  • Hemangioendothelioma is a rare vascular tumor with involvement of the liver, brain, long bones, and lung. Among the 6 histological subtypes, epithelioid hemangioendothelioma (EHE) is the most aggressive. Its occurrence in the mediastinum is quite rare, and very few cases have been documented. The reported cases in the literature have described difficulties in the preoperative diagnosis due to the unusual histological appearance of the tumor. Immunohistochemistry remains the mainstay for a definitive diagnosis. Due to its low incidence, there is no standard treatment for mediastinal EHE, but curative resection is the preferred treatment option where possible, with chemotherapy used as an adjuvant treatment or in cases of widespread inoperable disease. The present case study describes an aggressive EHE occurring in an 18-year-old woman in the anterior mediastinum.

Implementation of a portable telemetry system based on wavelet transform. (웨이블릿 알고리즘을 적용한 휴대용 텔레미트리 시스템)

  • 박차훈;서희돈
    • Proceedings of the IEEK Conference
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    • 2000.06e
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    • pp.113-116
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    • 2000
  • In this paper presents the portable wireless ECG data detection and diagnosis system based on discreet wavelet transform. An algorithm based on wavelet transform suitable for real time implementation has been developed in order to detect ECG characteristics. In particular, QRS complex, S and T waves may be distinguished form noise, baseline drift or artifacts. Proposed telemetry system that a transmitting media using radio frequency(RF) for the middle range measurement of the physiological signals and receiving media using optical for electromagnetic interference problem. A standard hi-directional serial communication interface between the telemetry system and a personal computer or laptop, allows read-time controlling, diagnosing and monitoring of system. A portable telemetry system within a size. of 65${\times}$125${\times}$45mm consists of three parts: a digital signal processing part for physiological signal detect or diagnose, RF transmitter for data transfer and a optical receiver for command receive. Advantages of proposed telemetry system is wireless middle range(50m) FM transmission, reduce electromagnetic interference to a minimum. which enables a comfortable diagnosis system at home.

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Maturity-onset Diabetes of the Young: Update on Diagnosis and Treatment

  • Jang, Kyung Mi
    • Journal of Interdisciplinary Genomics
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    • v.3 no.1
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    • pp.1-6
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    • 2021
  • Maturity-onset diabetes of the young (MODY) is characterized by a heterogeneous group of monogenic diabetes. MODY has autosomal dominant inheritance, a primary defect in pancreatic β-cell, and an early onset. Discriminating MODY from type 1 or type 2 diabetes is often challenging at first. To date, 14 different disease causing mutations have been identified in MODY patients worldwide. Targeted DNA sequencing is the gold standard to diagnose MODY and their asymptomatic relatives. Next-generation sequencing may help successfully to diagnose MODY patients and identify new MODY genes. In this review, the current perspectives on diagnosis and treatment of MODY and discrepancy in the disease-causing mutations between the Asian and Caucasian patients with MODY are summarized.

A Study on the Improvement of Test and Diagnosis Device for Audio Frequency Track Circuit (가청주파수 궤도회로의 진단 및 시험 장비 개선에 대한 연구)

  • Kang, Jang-Kyu;Kim, Jae-Chul
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.24 no.12
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    • pp.147-155
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    • 2010
  • We studied on performance improvement of TTM(TI21 Test Meter) that is test and diagnosis devices for jointless audio frequency track circuit on Korean electric railway TI21 standard. Upgraded devices is AD-TTM(Advanced TI21 Test Meter). This can measure alternating frequency USB(Upper signal band) and LSB(Lower signal band). In the audio frequency track circuit, ${\pm}17[Hz]$ of nominal frequency are demodulated and supplied to track relay through AND gate. It is important that measurement function which is error between USB and LSB. Need of AD-TTM will stand out in the electric railway system because this is simple and accurate rather than the former device.

Non-epileptic paroxysmal events during sleep - Differentiation from epileptic seizures - (수면시 발생하는 비간질성 발작 - 간질 발작과의 비교 -)

  • Lee, In Kyu
    • Clinical and Experimental Pediatrics
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    • v.50 no.8
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    • pp.726-731
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    • 2007
  • This review describes the wide spectrum of paroxysmal events during sleep in infancy and childhood. The differential diagnosis between sleep-related non-epileptic paroxysmal events and epileptic seizures is difficult in special occasions. The nocturnal frontal lobe seizure and of the more common nonepileptic paroxysmal events during sleep are described. The main differentiating features characterizing parasomnias are: onset in early childhood, rare episodes of long duration, relatively lower frequency per night, absence of stereotypy, gradual disappearance of older age. Video-polysomnography is the gold standard to diagnosing and differentiating parasomnias from nocturnal frontal lobe seizures.

Augmented renal clearance

  • Atkinson, Arthur J. Jr.
    • Translational and Clinical Pharmacology
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    • v.26 no.3
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    • pp.111-114
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    • 2018
  • Adding to the complexity of caring for critically ill patients is the fact that many of them have a creatinine clearance that exceeds $130mL/min/1.73m^2$. This phenomenon, termed augmented renal clearance (ARC), has only recently been widely recognized and its pathogenesis remains incompletely understood. However, ARC has been shown to result in increased dose requirements for drugs that are primarily eliminated by renal excretion, including many antimicrobial agents and enoxaparin. Recognition of ARC is hampered by the fact that the standard creatinine-based equations used to estimate renal function are not accurate in this clinical setting and the diagnosis is best established using both serum and urine creatinine measurements to calculate clearance. So a high index of clinical suspicion and awareness is usually required before this step is taken to confirm the diagnosis of ARC.

Development of Milk Progesterone Test(EIA) using Monoclonal Antibody and It's Application to Estrus-and Early Pregnancy Detection in Dairy Cattle (단일클론항체를 이용한 Milk Progesterone Test(EIA) 측정법의 개발과 이에 의한 소의 발정 및 임신조기진단의 정확도 향상에 관한 연구)

  • 김정우;홍승욱
    • Korean Journal of Animal Reproduction
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    • v.14 no.3
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    • pp.165-173
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    • 1990
  • A simple and sensitive microplate enzyme immunoassay(ELISA) was developed for progesterone, based on progesterone monoclonal antibody as anti-progesterone, horseradish peroxise(HRP) as enzyme-label and tetramethylbenzidine(TMB) as substrate. The assay has a sensitivity of 5pg-120pg/well and intra- and inter assay coefficients of variation for progesterone standard curve(0.1ng-3.2ng/ml) were ranged 4.4-10.6% and 5.-12.6%, respectively. They assay is performed in less than two hours and provide reliable values to differentiate among samples from day 0(A.I.), day 14 and day 19. The discriminatory levels for early pregnancy diagnosis are [>10ng(day 19) & decreasing rate <1.5 : pregnancy] and [ 7ng & decreasing rate 1.5 : non-pregnancy]. The accuracy of the pregnancy diagnosis for cows classified as positive(pregnancy) and negative(non-pregnancy) were 96% and 100%, respectively.

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Current Diagnosis and Management of Hypersensitivity Pneumonitis

  • Leone, Paolo Maria;Richeldi, Luca
    • Tuberculosis and Respiratory Diseases
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    • v.83 no.2
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    • pp.122-131
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    • 2020
  • Hypersensitivity Pneumonitis (HP) one of the most common interstitial lung diseases (ILDs) is characterized by exposure to an inhaled inciting antigen that leads to a host immunologic reaction determining interstitial inflammation and architectural distortion. The underlying pathogenetic mechanisms are unclear. The absence of international shared diagnostic guidelines and the lack of a "gold-standard" test for HP combined with the presence of several clinical and radiologic overlapping features makes it particularly challenging to differentiate HP from other ILDs, also in expert contests. Radiology is playing a more crucial role in this process; recently the headcheese sign was recognized as a more specific for chronic-HP than the extensive mosaic attenuation. Several classification proposals and diagnostic models have been advanced by different groups, with no prospective validation. Therapeutic options for HP have been limited to antigen avoidance and immunosuppressant drugs over the last decades. Several questions about this condition remain unanswered and there is a need for more studies.

A Study on the Diagnosis of Cutting Tool States Using Cutting Conditions and Cutting Force Parameters(II) -Decision Making- (절삭조건과 절삭력 파라메타를 이용한 공구상태 진단에 관한 연구(II) -의사결정 -)

  • 정진용;서남섭
    • Journal of the Korean Society for Precision Engineering
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    • v.15 no.4
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    • pp.105-110
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    • 1998
  • In this study, statistical and neural network methods were used to recognize the cutting tool states. This system employed the tool dynamometer and cutting force signals which are processed from the tool dynamometer sensor using linear discriminent function. To learn the necessary input/output mapping for turning operation diagnosis, the weights and thresholds of the neural network were adjusted according to the error back propagation method during off-line training. The cutting conditions, cutting force ratios and statistical values(standard deviation, coefficient of variation) attained from the cutting force signals were used as the inputs to the neural network. Through the suggested neural network a cutting tool states may be successfully diagnosed.

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A study on the 3-D standard value of mandible for the diagnosis of facial asymmetry (안면비대칭 진단을 위한 하악골 3차원영상 계측기준치에 관한 연구)

  • Ahn, Jeong-Soon;Lee, Ki-Heon;Hwang, Hyeon-Shik
    • The korean journal of orthodontics
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    • v.35 no.2 s.109
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    • pp.91-105
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    • 2005
  • For af accurate diagnosis and treatment planning of facial asymmetry, the use of 3-dimensional (3-D) image is indispensable. The purpose of this study was to get standard data for the 3-D analysis of facial asymmetry Computerized tomography (CT) was taken in the 60 normal occlusion individuals (30 male. 30 female) who did not have any apparent facial asymmetry. The acquired 2D CT DICOM data were input on a computer, and the reformatted 3-D images were created using a 3-D image software. Twenty three measurements were established in order to evaluate asymmetry; 15 ;omear measurements (6 for ramus length. 1 for condylar neck length, and 8 for mandibular body length) and 8 angular measurements (4 for gonial angle. 2 for frontal ramal inclination. and 2 for lateral ramal inclination) The right aid left difference of each measurement was calculated and analyzed. It is suggested that the right and left differences of the measurements obtained from the study could be used as references for the diagnosis of facial asymmetric patients.